{"id":"https://openalex.org/W4402390887","doi":"https://doi.org/10.12688/f1000research.154761.1","title":"UPLC-MS/MS analysis and chemical profile of Ficus pertusa L. bark, an ethnomedicinal resource from intertropical America.","display_name":"UPLC-MS/MS analysis and chemical profile of Ficus pertusa L. bark, an ethnomedicinal resource from intertropical America.","publication_year":2024,"publication_date":"2024-09-10","ids":{"openalex":"https://openalex.org/W4402390887","doi":"https://doi.org/10.12688/f1000research.154761.1","pmid":"https://pubmed.ncbi.nlm.nih.gov/41480482","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12754363"},"language":"en","primary_location":{"id":"doi:10.12688/f1000research.154761.1","doi":"https://doi.org/10.12688/f1000research.154761.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.154761.1","pdf_url":"https://f1000research.com/articles/13-1042/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4402390887"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://f1000research.com/articles/13-1042/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074947503","display_name":"Ricardo Diego Duarte Galhardo de Albuquerque","orcid":"https://orcid.org/0000-0002-8442-3849","observed_orcids":["https://orcid.org/0000-0002-8442-3849"]},"institutions":[{"id":"https://openalex.org/I4210091554","display_name":"National University of Trujillo","ror":"https://ror.org/001b4cb05","country_code":"PE","type":"education","lineage":["https://openalex.org/I4210091554"]}],"countries":["PE"],"is_corresponding":true,"raw_author_name":"Ricardo D.D.G. de Albuquerque","raw_affiliation_strings":["Laboratorio de Control de Calidad, Facultad de Farmacia y Bioqu\u00edmica, Universidad Nacional de Trujillo, Trujillo, La Libertad, 13001, Peru"],"raw_orcid":"https://orcid.org/0000-0002-8442-3849","affiliations":[{"raw_affiliation_string":"Laboratorio de Control de Calidad, Facultad de Farmacia y Bioqu\u00edmica, Universidad Nacional de Trujillo, Trujillo, La Libertad, 13001, Peru","institution_ids":["https://openalex.org/I4210091554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082854413","display_name":"Mayar Luis Ganoza-Yupanqui","orcid":"https://orcid.org/0000-0002-6114-1451","observed_orcids":["https://orcid.org/0000-0002-6114-1451"]},"institutions":[{"id":"https://openalex.org/I4210091554","display_name":"National University of Trujillo","ror":"https://ror.org/001b4cb05","country_code":"PE","type":"education","lineage":["https://openalex.org/I4210091554"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Mayar L. Ganoza-Yupanqui","raw_affiliation_strings":["Laboratorio de Control de Calidad, Facultad de Farmacia y Bioqu\u00edmica, Universidad Nacional de Trujillo, Trujillo, La Libertad, 13001, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Control de Calidad, Facultad de Farmacia y Bioqu\u00edmica, Universidad Nacional de Trujillo, Trujillo, La Libertad, 13001, Peru","institution_ids":["https://openalex.org/I4210091554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018067521","display_name":"Frank Romel Le\u00f3n-Vargas","orcid":"https://orcid.org/0000-0003-4874-743X","observed_orcids":["https://orcid.org/0000-0003-4874-743X"]},"institutions":[{"id":"https://openalex.org/I3130743028","display_name":"Universidad Nacional de la Amazon\u00eda Peruana","ror":"https://ror.org/05h6yvy73","country_code":"PE","type":"education","lineage":["https://openalex.org/I3130743028"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Frank Romel Le\u00f3n-Vargas","raw_affiliation_strings":["Departamento de Ingenier\u00eda Qu\u00edmica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazonia Peruana, Iquitos, Loreto, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Ingenier\u00eda Qu\u00edmica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazonia Peruana, Iquitos, Loreto, Peru","institution_ids":["https://openalex.org/I3130743028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107100479","display_name":"Rosa Isabel Souza-N\u00e1jar","orcid":"https://orcid.org/0000-0002-7359-3332","observed_orcids":["https://orcid.org/0000-0002-7359-3332"]},"institutions":[{"id":"https://openalex.org/I3130743028","display_name":"Universidad Nacional de la Amazon\u00eda Peruana","ror":"https://ror.org/05h6yvy73","country_code":"PE","type":"education","lineage":["https://openalex.org/I3130743028"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Rosa Souza-N\u00e1jar","raw_affiliation_strings":["Departamento de Quimica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazon\u00eda Peruana, Iquitos, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Quimica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazon\u00eda Peruana, Iquitos, Peru","institution_ids":["https://openalex.org/I3130743028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107100480","display_name":"Daniel D. Carrasco-Monta\u00f1ez","orcid":"https://orcid.org/0000-0002-2317-3911","observed_orcids":["https://orcid.org/0000-0002-2317-3911"]},"institutions":[{"id":"https://openalex.org/I3130743028","display_name":"Universidad Nacional de la Amazon\u00eda Peruana","ror":"https://ror.org/05h6yvy73","country_code":"PE","type":"education","lineage":["https://openalex.org/I3130743028"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Daniel Carrasco-Monta\u00f1ez","raw_affiliation_strings":["Departamento de Quimica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazon\u00eda Peruana, Iquitos, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Quimica, Facultad de Ingenier\u00eda Qu\u00edmica, Universidad Nacional de la Amazon\u00eda Peruana, Iquitos, Peru","institution_ids":["https://openalex.org/I3130743028"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107100481","display_name":"Yessenia Vanessa Sherrezade Ramos-Rivas","orcid":"https://orcid.org/0000-0003-3781-3163","observed_orcids":["https://orcid.org/0000-0003-3781-3163"]},"institutions":[{"id":"https://openalex.org/I3130743028","display_name":"Universidad Nacional de la Amazon\u00eda Peruana","ror":"https://ror.org/05h6yvy73","country_code":"PE","type":"education","lineage":["https://openalex.org/I3130743028"]}],"countries":["PE"],"is_corresponding":false,"raw_author_name":"Yessenia Ramos-Rivas","raw_affiliation_strings":["Departamento de Ciencias Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de la Amazonia Peruana, Iquitos, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Ciencias Cl\u00ednicas, Facultad de Medicina, Universidad Nacional de la Amazonia Peruana, Iquitos, Peru","institution_ids":["https://openalex.org/I3130743028"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5074947503"],"corresponding_institution_ids":["https://openalex.org/I4210091554"],"apc_list":{"value":1350,"currency":"USD","value_usd":1350},"apc_paid":{"value":1350,"currency":"USD","value_usd":1350},"fwci":0.4106,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54890434,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"13","issue":null,"first_page":"1042","last_page":"1042"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13422","display_name":"Phytochemistry and biological activities of Ficus species","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13422","display_name":"Phytochemistry and biological activities of Ficus species","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ficus-pertusa","display_name":"Ficus pertusa","score":1.0},{"id":"https://openalex.org/keywords/phytochemical-profile","display_name":"phytochemical composition","score":0.8379999995231628},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.6959999799728394},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9980000257492065},{"id":"https://openalex.org/keywords/proanthocyanidins","display_name":"proanthocyanidins","score":0.949999988079071},{"id":"https://openalex.org/keywords/phenolic-acids","display_name":"phenolic acids","score":0.8489999771118164},{"id":"https://openalex.org/keywords/procyanidins","display_name":"procyanidins","score":0.9789999723434448},{"id":"https://openalex.org/keywords/chlorogenic-acid","display_name":"chlorogenic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/luteolin","display_name":"luteolin","score":1.0},{"id":"https://openalex.org/keywords/ethnomedicinal-plants","display_name":"ethnomedicinal plants","score":0.7910000085830688},{"id":"https://openalex.org/keywords/hydroalcoholic-extract","display_name":"hydroalcoholic extract","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C2779362140","wikidata":"https://www.wikidata.org/wiki/Q1938846","display_name":"Ficus","level":2,"score":0.790074348449707},{"id":"https://openalex.org/C2983643791","wikidata":"https://www.wikidata.org/wiki/Q1999993","display_name":"Open peer review","level":3,"score":0.7791179418563843},{"id":"https://openalex.org/C2992936677","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Plant biology","level":2,"score":0.6831164956092834},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6483733057975769},{"id":"https://openalex.org/C133446333","wikidata":"https://www.wikidata.org/wiki/Q38681","display_name":"Bark (sound)","level":2,"score":0.5184266567230225},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4138081669807434},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3682044744491577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3011277914047241},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.29088228940963745},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.11162340641021729}],"mesh":[{"descriptor_ui":"D000097922","descriptor_name":"Liquid Chromatography-Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008519","descriptor_name":"Medicine, Traditional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D024301","descriptor_name":"Plant Bark","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D030681","descriptor_name":"Ficus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.12688/f1000research.154761.1","doi":"https://doi.org/10.12688/f1000research.154761.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.154761.1","pdf_url":"https://f1000research.com/articles/13-1042/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12754363","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12754363/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12754363/pdf/f1000research-13-169829.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Res","raw_type":"Text"},{"id":"pmid:41480482","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41480482","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9930fa4a524e45c3859eb8711b9374b8","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9930fa4a524e45c3859eb8711b9374b8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"F1000Research, Vol 13 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.12688/f1000research.154761.1","doi":"https://doi.org/10.12688/f1000research.154761.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/f1000research.154761.1","pdf_url":"https://f1000research.com/articles/13-1042/pdf","source":{"id":"https://openalex.org/S4210239046","display_name":"F1000Research","issn_l":"2046-1402","issn":["2046-1402"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320357","host_organization_name":"Faculty of 1000","host_organization_lineage":["https://openalex.org/P4310320357","https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Faculty of 1000","Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"F1000Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402390887.pdf","grobid_xml":"https://content.openalex.org/works/W4402390887.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W191813855","https://openalex.org/W1496576573","https://openalex.org/W1970714857","https://openalex.org/W2063490142","https://openalex.org/W2107180488","https://openalex.org/W2149475331","https://openalex.org/W2203232460","https://openalex.org/W2216606325","https://openalex.org/W2257510145","https://openalex.org/W2804636211","https://openalex.org/W2896926495","https://openalex.org/W2999394628","https://openalex.org/W3133277844","https://openalex.org/W4200495843","https://openalex.org/W4394794291"],"related_works":["https://openalex.org/W1942442339","https://openalex.org/W2795808022","https://openalex.org/W2975536244","https://openalex.org/W4378902486","https://openalex.org/W2186679677","https://openalex.org/W4311445073","https://openalex.org/W2606175308","https://openalex.org/W3006534999","https://openalex.org/W4295813843"],"abstract_inverted_index":{"Background":[0],"Ficus":[1],"pertusa":[2,47,125],"is":[3,22],"a":[4,89],"native":[5],"species":[6],"from":[7],"intertropical":[8],"America":[9],"used":[10],"for":[11],"medicinal":[12],"purpouses.":[13],"However,":[14],"despite":[15],"its":[16,27,54,132,145],"importance":[17],"as":[18,51,53,110],"ethnobotanical":[19],"resource,":[20],"there":[21],"poor":[23],"chemical":[24,61],"information":[25],"about":[26],"extracts.":[28],"Therefore,":[29],"the":[30,38,42,74,100,120,129,137,140],"objective":[31],"of":[32,41,45,102,119,123,131,139],"this":[33],"study":[34],"was":[35,63],"to":[36,70],"evaluate":[37],"phytochemical":[39],"profile":[40],"hydroalcoholic":[43],"extract":[44],"F.":[46,124],"barks":[48],"through":[49,84],"UPLC-MS/MS,":[50],"well":[52],"phenolic":[55,105],"and":[56,78,107,114,128],"flavonoid":[57],"content.":[58],"Methodology":[59],"The":[60,117],"identification":[62,118],"performed":[64],"by":[65],"Ultra-High":[66],"Liquid":[67],"Chromatography":[68],"coupled":[69],"Mass":[71],"Spectrometry,":[72],"whereas":[73],"Total":[75,79],"Phenolic":[76],"content":[77,134],"Flavonoid":[80],"quantification":[81],"were":[82,93],"measured":[83],"UV":[85],"spectrometry.":[86],"Results":[87],"As":[88],"result,":[90],"19":[91],"substances":[92,122],"identified,":[94],"which":[95],"are":[96],"mostly":[97],"included":[98],"within":[99],"group":[101],"condensed":[103],"tannins,":[104],"acids":[106],"flavonoids,":[108],"such":[109],"procyanidins,":[111],"chlorogenic":[112],"acid":[113],"luteolin.":[115],"Conclusion":[116],"main":[121],"\u2019s":[126],"bark":[127],"measurement":[130],"polyphenols":[133],"can":[135],"guide":[136],"understanding":[138],"pharmacological":[141],"mechanisms":[142],"involved":[143],"in":[144],"ethnomedicinal":[146],"uses.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2024-09-11T00:00:00"}