{"id":"https://openalex.org/W4402348314","doi":"https://doi.org/10.36233/0372-9311-528","title":"Virulence and tissue tropism of different epidemiologically significant SARS-CoV-2 variants for golden Syrian hamsters","display_name":"Virulence and tissue tropism of different epidemiologically significant SARS-CoV-2 variants for golden Syrian hamsters","publication_year":2024,"publication_date":"2024-09-09","ids":{"openalex":"https://openalex.org/W4402348314","doi":"https://doi.org/10.36233/0372-9311-528"},"language":"en","primary_location":{"id":"doi:10.36233/0372-9311-528","doi":"https://doi.org/10.36233/0372-9311-528","is_oa":true,"landing_page_url":"https://doi.org/10.36233/0372-9311-528","pdf_url":null,"source":{"id":"https://openalex.org/S2764630394","display_name":"Journal of microbiology epidemiology immunobiology","issn_l":"0372-9311","issn":["0372-9311","2686-7613"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4322614451","host_organization_name":"Central Research Institute for Epidemiology","host_organization_lineage":["https://openalex.org/P4322614451"],"host_organization_lineage_names":["Central Research Institute for Epidemiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology, epidemiology and immunobiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.36233/0372-9311-528","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013053131","display_name":"Anastasiia V. Gracheva","orcid":"https://orcid.org/0000-0001-8428-4482","observed_orcids":["https://orcid.org/0000-0001-8428-4482"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anastasiia V. Gracheva","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0000-0001-8428-4482","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094107687","display_name":"Andrey O. Drokov","orcid":"https://orcid.org/0009-0006-3300-8078","observed_orcids":["https://orcid.org/0009-0006-3300-8078"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Andrey O. Drokov","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0009-0006-3300-8078","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073474280","display_name":"Daria I. Smirnova","orcid":"https://orcid.org/0000-0001-7325-0834","observed_orcids":["https://orcid.org/0000-0001-7325-0834"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Daria I. Smirnova","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0000-0001-7325-0834","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047332414","display_name":"Darya M. Khokhlova","orcid":"https://orcid.org/0009-0003-5745-7589","observed_orcids":["https://orcid.org/0009-0003-5745-7589"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Darya M. Khokhlova","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0009-0003-5745-7589","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033439372","display_name":"E. R. Korchevaya","orcid":"https://orcid.org/0000-0002-6417-3301","observed_orcids":["https://orcid.org/0000-0002-6417-3301"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Ekaterina R. Korchevaya","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0000-0002-6417-3301","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040685964","display_name":"Andrey A. Pankratov","orcid":"https://orcid.org/0000-0001-7291-9743","observed_orcids":["https://orcid.org/0000-0001-7291-9743"]},"institutions":[{"id":"https://openalex.org/I4210139937","display_name":"P.A. Hertzen Moscow Oncology Research Institute","ror":"https://ror.org/04rbazs75","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210117042","https://openalex.org/I4210139937"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Andrey A. Pankratov","raw_affiliation_strings":["P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center"],"raw_orcid":"https://orcid.org/0000-0001-7291-9743","affiliations":[{"raw_affiliation_string":"P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center","institution_ids":["https://openalex.org/I4210139937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035299485","display_name":"Galina V. Trunova","orcid":"https://orcid.org/0000-0003-2917-4496","observed_orcids":["https://orcid.org/0000-0003-2917-4496"]},"institutions":[{"id":"https://openalex.org/I4210139937","display_name":"P.A. Hertzen Moscow Oncology Research Institute","ror":"https://ror.org/04rbazs75","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210117042","https://openalex.org/I4210139937"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Galina V. Trunova","raw_affiliation_strings":["P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center"],"raw_orcid":"https://orcid.org/0000-0003-2917-4496","affiliations":[{"raw_affiliation_string":"P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center","institution_ids":["https://openalex.org/I4210139937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003967319","display_name":"\u0425\u043e\u0445\u043b\u043e\u0432\u0430 \u0412\u0430\u0440\u0432\u0430\u0440\u0430 \u0410\u043d\u0434\u0440\u0435\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0002-0339-2068","observed_orcids":["https://orcid.org/0000-0002-0339-2068"]},"institutions":[{"id":"https://openalex.org/I4210139937","display_name":"P.A. Hertzen Moscow Oncology Research Institute","ror":"https://ror.org/04rbazs75","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210117042","https://openalex.org/I4210139937"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Varvara A. Khokhlova","raw_affiliation_strings":["P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center"],"raw_orcid":"https://orcid.org/0000-0002-0339-2068","affiliations":[{"raw_affiliation_string":"P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center","institution_ids":["https://openalex.org/I4210139937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106821520","display_name":"Maria S. Vorontsova","orcid":"https://orcid.org/0000-0002-9320-1746","observed_orcids":["https://orcid.org/0000-0002-9320-1746","https://orcid.org/0000-0002-1791-1375"]},"institutions":[{"id":"https://openalex.org/I4210139937","display_name":"P.A. Hertzen Moscow Oncology Research Institute","ror":"https://ror.org/04rbazs75","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210117042","https://openalex.org/I4210139937"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Maria S. Vorontsova","raw_affiliation_strings":["P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center"],"raw_orcid":"https://orcid.org/0000-0002-9320-1746","affiliations":[{"raw_affiliation_string":"P.A. Hertsen Moscow Oncology Research Institute \u2014 the branch of the National Medical Research Radiological Center","institution_ids":["https://openalex.org/I4210139937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070901028","display_name":"Irina A. Leneva","orcid":"https://orcid.org/0000-0002-7755-2714","observed_orcids":["https://orcid.org/0000-0002-7755-2714"]},"institutions":[{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina A. Leneva","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera"],"raw_orcid":"https://orcid.org/0000-0002-7755-2714","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera","institution_ids":["https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061488168","display_name":"\u041e. \u0410. \u0421\u0432\u0438\u0442\u0438\u0447","orcid":"https://orcid.org/0000-0003-1757-8389","observed_orcids":["https://orcid.org/0000-0003-1757-8389"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Oksana A. Svitich","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera; I.M. Sechenov First Moscow State Medical University (Sechenov University)"],"raw_orcid":"https://orcid.org/0000-0003-1757-8389","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera; I.M. Sechenov First Moscow State Medical University (Sechenov University)","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045371139","display_name":"\u0412. \u0412. \u0417\u0432\u0435\u0440\u0435\u0432","orcid":"https://orcid.org/0000-0001-5808-2246","observed_orcids":["https://orcid.org/0000-0001-5808-2246"]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vitaly V. Zverev","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera; I.M. Sechenov First Moscow State Medical University (Sechenov University)"],"raw_orcid":"https://orcid.org/0000-0001-5808-2246","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera; I.M. Sechenov First Moscow State Medical University (Sechenov University)","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210130895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004889419","display_name":"\u0415. \u0411. \u0424\u0430\u0439\u0437\u0443\u043b\u043e\u0435\u0432","orcid":"https://orcid.org/0000-0001-7385-5083","observed_orcids":["https://orcid.org/0000-0001-7385-5083"]},"institutions":[{"id":"https://openalex.org/I4210108300","display_name":"Russian Medical Academy of Continuous Professional Education","ror":"https://ror.org/01t6bjk79","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210108300","https://openalex.org/I4210117042"]},{"id":"https://openalex.org/I4210130895","display_name":"Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences","ror":"https://ror.org/03bk73w20","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210130895"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Evgeny B. Faizuloev","raw_affiliation_strings":["I.I. Mechnikov Research Institute for Vaccines and Sera; Russian Medical Academy of Continuous Professional Education"],"raw_orcid":"https://orcid.org/0000-0001-7385-5083","affiliations":[{"raw_affiliation_string":"I.I. Mechnikov Research Institute for Vaccines and Sera; Russian Medical Academy of Continuous Professional Education","institution_ids":["https://openalex.org/I4210108300","https://openalex.org/I4210130895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.502,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.79511278,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"101","issue":"4","first_page":"470","last_page":"482"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9399999976158142},{"id":"https://openalex.org/keywords/syrian-hamster","display_name":"golden hamster","score":0.8700000047683716},{"id":"https://openalex.org/keywords/animal-model-of-covid-19","display_name":"animal model of COVID-19","score":0.9070000052452087},{"id":"https://openalex.org/keywords/virus-virulence","display_name":"viral virulence","score":0.871999979019165},{"id":"https://openalex.org/keywords/tissue-tropism","display_name":"tissue tropism","score":0.9990000128746033},{"id":"https://openalex.org/keywords/omicron-ba-1","display_name":"Omicron BA.1","score":0.7990000247955322},{"id":"https://openalex.org/keywords/omicron-ba-5","display_name":"Omicron BA.5","score":0.949999988079071},{"id":"https://openalex.org/keywords/delta-variant","display_name":"Delta variant","score":0.9879999756813049},{"id":"https://openalex.org/keywords/lung-histopathology","display_name":"lung histopathology","score":0.8410000205039978},{"id":"https://openalex.org/keywords/pneumonia-severity","display_name":"pneumonia severity","score":0.7110000252723694},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.8410000205039978},{"id":"https://openalex.org/keywords/central-nervous-system-infection","display_name":"central nervous system infection","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.8069952726364136},{"id":"https://openalex.org/C35693153","wikidata":"https://www.wikidata.org/wiki/Q239762","display_name":"Tropism","level":3,"score":0.8039278984069824},{"id":"https://openalex.org/C33602714","wikidata":"https://www.wikidata.org/wiki/Q7809666","display_name":"Tissue tropism","level":4,"score":0.738071620464325},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.677512526512146},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6259812712669373},{"id":"https://openalex.org/C2910480608","wikidata":"https://www.wikidata.org/wiki/Q204175","display_name":"Syrian hamsters","level":3,"score":0.578045129776001},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.5458959341049194},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5102131366729736},{"id":"https://openalex.org/C2779525107","wikidata":"https://www.wikidata.org/wiki/Q389919","display_name":"Mesocricetus","level":3,"score":0.4823440909385681},{"id":"https://openalex.org/C3020799909","wikidata":"https://www.wikidata.org/wiki/Q85438966","display_name":"Sars virus","level":5,"score":0.478044331073761},{"id":"https://openalex.org/C2778362869","wikidata":"https://www.wikidata.org/wiki/Q204175","display_name":"Golden hamster","level":3,"score":0.43220099806785583},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.41371122002601624},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.4093540906906128},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23351579904556274},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.19071030616760254},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18960914015769958},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.10492148995399475},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.1043873131275177},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0818968415260315},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.07122999429702759},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.062113434076309204},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.05850261449813843}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.36233/0372-9311-528","doi":"https://doi.org/10.36233/0372-9311-528","is_oa":true,"landing_page_url":"https://doi.org/10.36233/0372-9311-528","pdf_url":null,"source":{"id":"https://openalex.org/S2764630394","display_name":"Journal of microbiology epidemiology immunobiology","issn_l":"0372-9311","issn":["0372-9311","2686-7613"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4322614451","host_organization_name":"Central Research Institute for Epidemiology","host_organization_lineage":["https://openalex.org/P4322614451"],"host_organization_lineage_names":["Central Research Institute for Epidemiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology, epidemiology and immunobiology","raw_type":"journal-article"},{"id":"pmh:https://cyberleninka.ru/article/n/virulence-and-tissue-tropism-of-different-epidemiologically-significant-sars-cov-2-variants-for-golden-syrian-hamsters","doi":null,"is_oa":false,"landing_page_url":"https://cyberleninka.ru/article/n/virulence-and-tissue-tropism-of-different-epidemiologically-significant-sars-cov-2-variants-for-golden-syrian-hamsters","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:doaj.org/article:67b3e4c1e1c640dc852ad3f8d140bbbc","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/67b3e4c1e1c640dc852ad3f8d140bbbc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0416\u0443\u0440\u043d\u0430\u043b \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0438, \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u0438\u043c\u043c\u0443\u043d\u043e\u0431\u0438\u043e\u043b\u043e\u0433\u0438\u0438, Vol 101, Iss 4, Pp 470-482 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.36233/0372-9311-528","doi":"https://doi.org/10.36233/0372-9311-528","is_oa":true,"landing_page_url":"https://doi.org/10.36233/0372-9311-528","pdf_url":null,"source":{"id":"https://openalex.org/S2764630394","display_name":"Journal of microbiology epidemiology immunobiology","issn_l":"0372-9311","issn":["0372-9311","2686-7613"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4322614451","host_organization_name":"Central Research Institute for Epidemiology","host_organization_lineage":["https://openalex.org/P4322614451"],"host_organization_lineage_names":["Central Research Institute for Epidemiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology, epidemiology and immunobiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1266297804","https://openalex.org/W2057172638","https://openalex.org/W2474614962","https://openalex.org/W2772980892","https://openalex.org/W2977714223","https://openalex.org/W3009219040","https://openalex.org/W3012831148","https://openalex.org/W3021880084","https://openalex.org/W3025871232","https://openalex.org/W3026265675","https://openalex.org/W3036887118","https://openalex.org/W3041348343","https://openalex.org/W3084027778","https://openalex.org/W3088521725","https://openalex.org/W3107525025","https://openalex.org/W3134034046","https://openalex.org/W3151763409","https://openalex.org/W3173951993","https://openalex.org/W4205521972","https://openalex.org/W4214825457","https://openalex.org/W4214935151","https://openalex.org/W4223572329","https://openalex.org/W4283321764","https://openalex.org/W4283643113","https://openalex.org/W4284701650","https://openalex.org/W4285891468","https://openalex.org/W4288179245","https://openalex.org/W4294669030","https://openalex.org/W4296119731","https://openalex.org/W4306385427","https://openalex.org/W4307650443","https://openalex.org/W4311518275","https://openalex.org/W4313361127","https://openalex.org/W4317213682","https://openalex.org/W4381930561","https://openalex.org/W4385443024","https://openalex.org/W4387079893","https://openalex.org/W4388040217","https://openalex.org/W4391883024","https://openalex.org/W4392295759","https://openalex.org/W4392623528","https://openalex.org/W4393853524"],"related_works":["https://openalex.org/W4307780777","https://openalex.org/W4220729450","https://openalex.org/W4308302988","https://openalex.org/W4311518275","https://openalex.org/W4388451568","https://openalex.org/W4283164367","https://openalex.org/W4214908959","https://openalex.org/W4313727994","https://openalex.org/W4220860951","https://openalex.org/W4297536225"],"abstract_inverted_index":{"Introduction.":[0],"Animal":[1],"models":[2],"for":[3,17,31,50,119,273,293,298],"SARS-CoV-2":[4,55,79,86],"infection,":[5],"reproducing":[6],"the":[7,19,22,26,40,45,92,116,125,142,161,164,168,175,181,191,196,214,228,243,253,264,269,279,286],"clinical":[8],"features":[9],"of":[10,21,25,39,54,85,94,127,155,163,167,180,234,238,245,255,263,275,302],"COVID-19":[11,294],"in":[12,98,103,105,133,141,201,213,226,241,251],"humans,":[13],"are":[14,29],"important":[15],"tools":[16],"studying":[18],"pathogenesis":[20],"disease,":[23],"transmission":[24],"pathogen":[27],"and":[28,35,47,67,71,82,100,107,130,146,151,177,193,219,258,281],"indispensable":[30],"testing":[32],"antiviral":[33,303],"drugs":[34],"vaccines.":[36],"The":[37,111],"aim":[38],"study":[41],"was":[42,122,160,203,237],"to":[43,58,190,278,285],"assess":[44],"virulence":[46,118,272],"tissue":[48,83],"tropism":[49,84],"golden":[51],"Syrian":[52],"hamsters":[53,184,274],"strains":[56,87],"belonging":[57,189,277],"different":[59,78],"epidemiologically":[60],"significant":[61],"variants:":[62],"Wuhan-like,":[63],"Delta,":[64],"Omicron":[65,68,194,282],"BA.1.1":[66],"BA.5.2.":[69],"Materials":[70],"methods.":[72],"Hamsters":[73],"were":[74,88,185],"intranasally":[75],"infected":[76,106,186],"with":[77,187],"strains.":[80],"Virulence":[81],"assessed":[89],"by":[90,124,136],"comparing":[91],"dynamics":[93],"weight,":[95],"viral":[96,211],"load":[97,212],"organs":[99,221],"histopathological":[101],"changes":[102],"lungs":[104],"uninfected":[108],"animals.":[109,182],"Results.":[110],"Wuhan-like":[112,165],"Dubrovka":[113],"strain":[114],"had":[115],"greatest":[117],"hamsters,":[120],"which":[121],"manifested":[123],"development":[126],"severe":[128],"pneumonia":[129],"a":[131,223,260],"delay":[132],"weight":[134,176,199],"gain":[135],"14.6%,":[137],"high":[138],"virus":[139,166,229],"content":[140],"lungs,":[143,215],"nasal":[144,216],"passages":[145],"brain":[147],"\u2014":[148],"6.2,":[149],"5,9":[150],"3.7":[152],"lg":[153],"TCID50/ml":[154],"homogenate,":[156],"respectively.":[157],"Presumably,":[158],"it":[159,248],"infection":[162],"central":[169],"nervous":[170],"system":[171],"that":[172],"negatively":[173],"affected":[174],"general":[178],"condition":[179],"When":[183],"viruses":[188,276],"Delta":[192,280],"variants,":[195],"observed":[197],"minor":[198],"loss":[200],"animals":[202],"uninformative,":[204],"so":[205],"indicators":[206],"such":[207],"as":[208],"lung":[209,235],"histopathology,":[210],"passages,":[217],"heart":[218],"other":[220],"played":[222],"decisive":[224],"role":[225],"assessing":[227,242],"pathogenicity.":[230],"A":[231],"score":[232],"assessment":[233,262],"histopathology":[236],"particular":[239],"value":[240,297],"severity":[244],"pneumonia,":[246],"since":[247],"reduced":[249],"subjectivity":[250],"evaluating":[252],"results":[254],"histological":[256],"examination":[257],"provided":[259],"semi-quantitative":[261],"pathological":[265],"process.":[266],"Conclusion.":[267],"Despite":[268],"revealed":[270],"lower":[271],"variants":[283],"compared":[284],"ancestral":[287],"Wuhan":[288],"virus,":[289],"this":[290],"animal":[291],"model":[292],"retains":[295],"its":[296],"conducting":[299],"preclinical":[300],"trials":[301],"drugs.":[304]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2024-09-10T00:00:00"}