{"id":"https://openalex.org/W4402272136","doi":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","title":"Assessment of efficacy of different combination of antihypertensive drugs in the treatment of arterial hypertension","display_name":"Assessment of efficacy of different combination of antihypertensive drugs in the treatment of arterial hypertension","publication_year":2024,"publication_date":"2024-08-14","ids":{"openalex":"https://openalex.org/W4402272136","doi":"https://doi.org/10.69605/ijlbpr_13.8.2024.29"},"language":"en","primary_location":{"id":"doi:10.69605/ijlbpr_13.8.2024.29","doi":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","is_oa":true,"landing_page_url":"http://dx.doi.org/10.69605/ijlbpr_13.8.2024.29","pdf_url":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","source":{"id":"https://openalex.org/S4404663798","display_name":"International journal of life sciences, biotechnology and pharma research.","issn_l":"2250-3137","issn":["2250-3137","2977-0122"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4404663797","host_organization_name":"Chaudhary Ranbir Singh University","host_organization_lineage":["https://openalex.org/P4404663797"],"host_organization_lineage_names":["Chaudhary Ranbir Singh University"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Life Sciences Biotechnology and Pharma Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085422274","display_name":"Amit Gupta","orcid":"https://orcid.org/0000-0002-8395-1201","observed_orcids":["https://orcid.org/0000-0002-8395-1201"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit Gupta","raw_affiliation_strings":["Assistant Professor, Department of Community Medicine , SSJ Govt. IMSR , Almora , Uttarakhand , India","Assistant Professor, Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Community Medicine , SSJ Govt. IMSR , Almora , Uttarakhand , India","institution_ids":[]},{"raw_affiliation_string":"Assistant Professor, Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sneha Mittal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sneha Mittal","raw_affiliation_strings":["Associate Professor & HOD , Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Professor & HOD , Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111502609","display_name":"Pratik Pratik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pratik .","raw_affiliation_strings":["Associate Professor & HOD , Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Associate Professor & HOD , Department of Pharmacology , SSJ Govt. IMSR , Almora , Uttarakhand , India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25017491,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"8","first_page":"178","last_page":"180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8820000290870667},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.9919999837875366},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7639999985694885},{"id":"https://openalex.org/keywords/drug-efficacy","display_name":"drug efficacy","score":0.7080000042915344},{"id":"https://openalex.org/keywords/blood-pressure-reduction","display_name":"blood pressure reduction","score":0.5}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6379594802856445},{"id":"https://openalex.org/C2780192228","wikidata":"https://www.wikidata.org/wiki/Q575890","display_name":"Antihypertensive drug","level":3,"score":0.45963364839553833},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.40558668971061707},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3907507658004761},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3478511869907379},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32403233647346497}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.69605/ijlbpr_13.8.2024.29","doi":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","is_oa":true,"landing_page_url":"http://dx.doi.org/10.69605/ijlbpr_13.8.2024.29","pdf_url":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","source":{"id":"https://openalex.org/S4404663798","display_name":"International journal of life sciences, biotechnology and pharma research.","issn_l":"2250-3137","issn":["2250-3137","2977-0122"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4404663797","host_organization_name":"Chaudhary Ranbir Singh University","host_organization_lineage":["https://openalex.org/P4404663797"],"host_organization_lineage_names":["Chaudhary Ranbir Singh University"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Life Sciences Biotechnology and Pharma Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.69605/ijlbpr_13.8.2024.29","doi":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","is_oa":true,"landing_page_url":"http://dx.doi.org/10.69605/ijlbpr_13.8.2024.29","pdf_url":"https://doi.org/10.69605/ijlbpr_13.8.2024.29","source":{"id":"https://openalex.org/S4404663798","display_name":"International journal of life sciences, biotechnology and pharma research.","issn_l":"2250-3137","issn":["2250-3137","2977-0122"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4404663797","host_organization_name":"Chaudhary Ranbir Singh University","host_organization_lineage":["https://openalex.org/P4404663797"],"host_organization_lineage_names":["Chaudhary Ranbir Singh University"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Life Sciences Biotechnology and Pharma Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402272136.pdf","grobid_xml":"https://content.openalex.org/works/W4402272136.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2410878090","https://openalex.org/W2435339062","https://openalex.org/W2397900540","https://openalex.org/W2400526461","https://openalex.org/W2473604698","https://openalex.org/W2412540701","https://openalex.org/W2409266869","https://openalex.org/W2411852440","https://openalex.org/W2412029749","https://openalex.org/W2423847040"],"abstract_inverted_index":{"Background:":[0],"Despite":[1],"the":[2,16,20,33,40,49,63,72,93,146,166,185,193,201,231,234],"well-established":[3],"epidemiological":[4],"link":[5],"between":[6,200],"high":[7],"blood":[8,25,194],"pressure":[9,26,195],"and":[10,13,15,125,154,173,181,226],"cardiovascular":[11],"morbidity":[12],"mortality,":[14],"substantial":[17],"evidence":[18],"supporting":[19],"need":[21],"for":[22,38,61],"antihypertensive":[23,46,69],"therapy,":[24],"control":[27],"remains":[28],"inadequate":[29],"in":[30,48,71,150,192,199],"many":[31],"cases.Hence;":[32],"present":[34,57],"study":[35,58,100,144,187,203],"was":[36,59,140,176,207],"conducted":[37,60],"comparing":[39,62,198],"efficacy":[41,64],"of":[42,45,51,65,68,74,78,83,91,98,165,168,211,233],"different":[43,66],"combination":[44,67],"drugs":[47,70],"treatment":[50,73],"arterial":[52,75,84],"hypertension.Materials":[53],"&":[54],"methods:":[55],"The":[56],"hypertension.A":[76],"total":[77,97],"60":[79],"patients":[80,94,167,210],"with":[81],"presence":[82],"hypertension":[85,219],"were":[86,95,102,148,155],"enrolled.Complete":[87],"demographic":[88],"clinical":[89],"details":[90],"all":[92],"obtained.A":[96],"three":[99,143,186],"groups":[101,188],"formed":[103],"as":[104],"follows:":[105],"Group":[106,126],"1:":[107],"Calcium":[108,128],"Channel":[109,129],"Blocker":[110,115,120,130,135],"(Amlodipine)":[111,131],"+":[112,122,132,137],"Angiotensin":[113,118,133],"Receptor":[114,119,134],"(Valsartan),Group":[116],"2:":[117],"(Valsartan)":[121,136],"Diuretic":[123,138],"(Hydrochlorothiazide),":[124],"3:":[127],"(Hydrochlorothiazide).Comparison":[139],"made":[141],"among":[142,209],"groups.All":[145],"results":[147],"recorded":[149],"Microsoft":[151],"excel":[152],"sheet":[153],"subjected":[156],"to":[157],"statistical":[158],"analysis":[159],"using":[160],"SPSS":[161],"software.Results:":[162],"Mean":[163],"age":[164],"group":[169,171,174,212],"A,":[170],"B":[172],"C":[175],"42.3":[177],"years,":[178],"45.9":[179],"years":[180,183],"44.1":[182],"respectively.All":[184],"showed":[189],"significant":[190],"improvement":[191,206],"posttreatment.However;":[196],"while":[197],"individual":[202],"groups,":[204],"maximum":[205],"seen":[208],"A.":[213],"Conclusion:":[214],"Key":[215],"words:":[216],"Antihypertensive,":[217],"Arterial":[218],"This":[220],"is":[221],"an":[222],"open":[223],"access":[224],"journal,":[225],"articles":[227],"are":[228],"distributed":[229],"under":[230],"terms":[232],"Creative":[235],"Commons":[236],"Attribution-Non":[237],"Commercial-Share":[238],"Alike":[239],"4.0":[240]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2024-09-06T00:00:00"}
