{"id":"https://openalex.org/W4402139592","doi":"https://doi.org/10.1177/02698811241275627","title":"Is lack of goal-conflict-specific rhythmicity a biomarker for treatment resistance in generalised anxiety but not social anxiety or major depression?","display_name":"Is lack of goal-conflict-specific rhythmicity a biomarker for treatment resistance in generalised anxiety but not social anxiety or major depression?","publication_year":2024,"publication_date":"2024-09-01","ids":{"openalex":"https://openalex.org/W4402139592","doi":"https://doi.org/10.1177/02698811241275627","pmid":"https://pubmed.ncbi.nlm.nih.gov/39219452"},"language":"en","primary_location":{"id":"doi:10.1177/02698811241275627","doi":"https://doi.org/10.1177/02698811241275627","is_oa":true,"landing_page_url":"https://doi.org/10.1177/02698811241275627","pdf_url":null,"source":{"id":"https://openalex.org/S136368880","display_name":"Journal of Psychopharmacology","issn_l":"0269-8811","issn":["0269-8811","1461-7285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1177/02698811241275627","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055556361","display_name":"Shabah M. Shadli","orcid":"https://orcid.org/0000-0002-3607-3469","observed_orcids":["https://orcid.org/0000-0002-3607-3469"]},"institutions":[{"id":"https://openalex.org/I153230381","display_name":"Charles Sturt University","ror":"https://ror.org/00wfvh315","country_code":"AU","type":"education","lineage":["https://openalex.org/I153230381"]},{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["AU","NZ"],"is_corresponding":false,"raw_author_name":"Shabah M Shadli","raw_affiliation_strings":["Department of Psychology, University of Otago, Dunedin, New Zealand","School of Psychology, Charles Sturt University, Bathurst, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"School of Psychology, Charles Sturt University, Bathurst, NSW, Australia","institution_ids":["https://openalex.org/I153230381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107168524","display_name":"Carina Joy Donegan","orcid":"https://orcid.org/0009-0005-6936-4587","observed_orcids":["https://orcid.org/0009-0005-6936-4587"]},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Carina J Donegan","raw_affiliation_strings":["Department of Psychology, University of Otago, Dunedin, New Zealand","School of Psychology, University of Auckland, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"School of Psychology, University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Muhammad SS Bin Mohd Fahmi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Muhammad SS Bin Mohd Fahmi","raw_affiliation_strings":["Department of Psychology, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bruce R Russell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Bruce R Russell","raw_affiliation_strings":["School of Pharmacy, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022110262","display_name":"Paul Glue","orcid":"https://orcid.org/0000-0002-7305-2800","observed_orcids":["https://orcid.org/0000-0002-7305-2800"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Paul Glue","raw_affiliation_strings":["Department of Psychological Medicine, University of Otago, Dunedin, New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-7305-2800","affiliations":[{"raw_affiliation_string":"Department of Psychological Medicine, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010069066","display_name":"Neil McNaughton","orcid":"https://orcid.org/0000-0003-4348-8221","observed_orcids":["https://orcid.org/0000-0003-4348-8221"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Neil McNaughton","raw_affiliation_strings":["Department of Psychology, University of Otago, Dunedin, New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-4348-8221","affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5010069066"],"corresponding_institution_ids":["https://openalex.org/I80281795"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":{"value":4200,"currency":"USD","value_usd":4200},"fwci":0.804,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.77444422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"38","issue":"9","first_page":"789","last_page":"797"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/treatment-resistance","display_name":"treatment resistance","score":0.8190000057220459},{"id":"https://openalex.org/keywords/generalized-anxiety-disorder","display_name":"generalized anxiety disorder","score":0.9829999804496765},{"id":"https://openalex.org/keywords/social-anxiety-disorder","display_name":"social anxiety disorder","score":0.8970000147819519},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.8100000023841858},{"id":"https://openalex.org/keywords/neural-markers","display_name":"neural markers","score":0.6269999742507935},{"id":"https://openalex.org/keywords/stop-signal-task","display_name":"stop-signal task","score":0.9520000219345093},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"EEG","score":0.4009999930858612},{"id":"https://openalex.org/keywords/low-frequency-oscillations","display_name":"low-frequency oscillations","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.818041980266571},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.6254045963287354},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.5948500633239746},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5792867541313171},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.5386867523193359},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5012519359588623},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.472432941198349},{"id":"https://openalex.org/C2777545354","wikidata":"https://www.wikidata.org/wiki/Q3557657","display_name":"Social anxiety","level":3,"score":0.46001550555229187},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000072861","descriptor_name":"Phobia, Social","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003220","descriptor_name":"Conflict, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Depressive Disorder, Major","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006040","descriptor_name":"Goals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D061218","descriptor_name":"Depressive Disorder, Treatment-Resistant","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1177/02698811241275627","doi":"https://doi.org/10.1177/02698811241275627","is_oa":true,"landing_page_url":"https://doi.org/10.1177/02698811241275627","pdf_url":null,"source":{"id":"https://openalex.org/S136368880","display_name":"Journal of Psychopharmacology","issn_l":"0269-8811","issn":["0269-8811","1461-7285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychopharmacology","raw_type":"journal-article"},{"id":"pmid:39219452","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39219452","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of psychopharmacology (Oxford, England)","raw_type":"Journal Article"},{"id":"pmh:oai:rune.une.edu.au:1959.11/63337","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1959.11/63337","pdf_url":"https://rune.une.edu.au/bitstreams/c22b978a-df75-4f41-94f7-104064462b3c/download","source":{"id":"https://openalex.org/S7407055448","display_name":"RUNE (Research UNE)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11453030","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11453030","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11453030/pdf/10.1177_02698811241275627.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Psychopharmacol","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:publications/5c5b45ed-17ff-4849-829e-d29ec7d00601","doi":null,"is_oa":true,"landing_page_url":"https://researchoutput.csu.edu.au/en/publications/5c5b45ed-17ff-4849-829e-d29ec7d00601","pdf_url":null,"source":{"id":"https://openalex.org/S7407055442","display_name":"Charles Sturt University Research Output (CRO)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Shadli, S M, Donegan, C J, Bin Mohd Fahmi, M S S, Russell, B R, Glue, P & McNaughton, N 2024, 'Is lack of goal-conflict-specific rhythmicity a biomarker for treatment resistance in generalised anxiety but not social anxiety or major depression?', Journal of Psychopharmacology, vol. 38, no. 9, pp. 789-797. https://doi.org/10.1177/02698811241275627","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1177/02698811241275627","doi":"https://doi.org/10.1177/02698811241275627","is_oa":true,"landing_page_url":"https://doi.org/10.1177/02698811241275627","pdf_url":null,"source":{"id":"https://openalex.org/S136368880","display_name":"Journal of Psychopharmacology","issn_l":"0269-8811","issn":["0269-8811","1461-7285"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Psychopharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7900000214576721,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G965319961","display_name":null,"funder_award_id":"20-112","funder_id":"https://openalex.org/F4320334749","funder_display_name":"Health Research Council of New Zealand"}],"funders":[{"id":"https://openalex.org/F4320320290","display_name":"University of Oxford","ror":"https://ror.org/052gg0110"},{"id":"https://openalex.org/F4320334749","display_name":"Health Research Council of New Zealand","ror":"https://ror.org/00zbf3d93"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W756771814","https://openalex.org/W1040825594","https://openalex.org/W1138769378","https://openalex.org/W1969010498","https://openalex.org/W1977465442","https://openalex.org/W1979171795","https://openalex.org/W1980039722","https://openalex.org/W1985480297","https://openalex.org/W1992656257","https://openalex.org/W2000872281","https://openalex.org/W2004030076","https://openalex.org/W2004241099","https://openalex.org/W2039218905","https://openalex.org/W2039729702","https://openalex.org/W2052902755","https://openalex.org/W2072646528","https://openalex.org/W2077888611","https://openalex.org/W2082945637","https://openalex.org/W2090762740","https://openalex.org/W2093427998","https://openalex.org/W2094748465","https://openalex.org/W2094955630","https://openalex.org/W2098750462","https://openalex.org/W2119314959","https://openalex.org/W2122660499","https://openalex.org/W2124516067","https://openalex.org/W2172219833","https://openalex.org/W2200777730","https://openalex.org/W2233618464","https://openalex.org/W2254793667","https://openalex.org/W2310068783","https://openalex.org/W2406028382","https://openalex.org/W2519174895","https://openalex.org/W2607995088","https://openalex.org/W2608289281","https://openalex.org/W2625860417","https://openalex.org/W2745262067","https://openalex.org/W2752067567","https://openalex.org/W2767038418","https://openalex.org/W2789464286","https://openalex.org/W2945604426","https://openalex.org/W2949370843","https://openalex.org/W2952574438","https://openalex.org/W2952777334","https://openalex.org/W2981767691","https://openalex.org/W3011728974","https://openalex.org/W3155007213","https://openalex.org/W3203275095","https://openalex.org/W4247665917","https://openalex.org/W4280546770","https://openalex.org/W4366658060","https://openalex.org/W4399746595"],"related_works":["https://openalex.org/W1978188354","https://openalex.org/W3141224953","https://openalex.org/W2155091457","https://openalex.org/W4240532399","https://openalex.org/W2765738011","https://openalex.org/W4387318495","https://openalex.org/W2157868280","https://openalex.org/W2002142585","https://openalex.org/W2964000526","https://openalex.org/W2378173657"],"abstract_inverted_index":{"BACKGROUND:":[0],"Anxiety":[1],"and":[2,11,50,72,93,96,108,124,127,135,197,202,210,216],"depression":[3],"cause":[4],"major":[5],"detriment":[6],"to":[7,28,105,237],"the":[8,58,64,143,155,162,203,227],"patient,":[9],"family,":[10],"society":[12],"-":[13],"particularly":[14],"in":[15,47,151,161,170,189],"treatment-resistant":[16],"(TR)":[17],"cases,":[18],"which":[19],"are":[20,233],"highly":[21],"prevalent.":[22],"TR":[23,92,118,166],"prevalence":[24],"may":[25,62,187],"be":[26,222],"due":[27],"current":[29],"diagnoses":[30,102],"being":[31,199,212],"based":[32],"not":[33,178],"on":[34,38],"biological":[35],"measures":[36],"but":[37],"symptom":[39,48],"lists":[40],"that":[41,87,185,232],"suffer":[42],"from":[43,116,194,206],"clinical":[44],"subjectivity,":[45],"variation":[46],"presentation,":[49],"comorbidity.":[51],"AIMS:":[52],"Goal-conflict-specific":[53],"rhythmicity":[54],"(GCSR)":[55],"measured":[56],"using":[57],"Stop-Signal":[59],"Task":[60],"(SST)":[61],"provide":[63],"first":[65],"neural":[66],"biomarker":[67],"for":[68,82],"an":[69],"anxiety":[70],"process":[71],"disorder.":[73],"This":[74],"GCSR":[75,88,150,160,196,220],"has":[76],"been":[77],"validated":[78],"with":[79,175],"selective":[80,106],"drugs":[81],"anxiety.":[83],"So,":[84],"we":[85],"proposed":[86],"could":[89,221],"differ":[90],"between":[91,100],"non-TR":[94,129],"individuals":[95],"do":[97],"so":[98,198,211],"differently":[99],"those":[101,109],"normally":[103,234],"sensitive":[104,236],"anxiolytics":[107],"not.":[110],"METHODS:":[111],"We":[112],"recorded":[113],"electroencephalograms":[114],"(EEG)":[115],"20":[117],"participants":[119,130],"(4":[120,131],"GAD,":[121,132],"5":[122,133],"SAD":[123,134,171,215],"11":[125],"MDD)":[126],"24":[128],"15":[136],"Comorbid":[137],"GAD/MDD":[138],"(GMD))":[139],"while":[140],"they":[141],"performed":[142],"SST.":[144],"RESULTS:":[145],"There":[146],"was":[147],"significant":[148],"positive":[149],"all":[152],"groups":[153],"except":[154],"GAD-TR":[156,158],"group.":[157],"lacked":[159],"low-frequency":[163],"range.":[164],"However,":[165],"had":[167],"little":[168],"effect":[169],"or":[172],"MDD/GMD":[173],"populations":[174],"apparent":[176],"increases":[177],"decreases.":[179],"CONCLUSIONS:":[180],"Overall,":[181],"these":[182],"results":[183],"suggest":[184],"GAD":[186],"occur":[188],"two":[190],"forms:":[191],"one":[192],"resulting":[193,205],"excessive":[195],"drug":[200],"sensitive,":[201],"other":[204,208],"some":[207],"mechanism":[209],"TR.":[213],"In":[214],"MDD":[217],"groups,":[218],"heightened":[219],"a":[223],"consequence":[224],"rather":[225],"than":[226],"cause,":[228],"driven":[229],"by":[230],"mechanisms":[231],"more":[235],"non-selective":[238],"panicolytic":[239],"antidepressants.":[240]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}