{"id":"https://openalex.org/W4402137264","doi":"https://doi.org/10.26434/chemrxiv-2024-4t52c","title":"Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva","display_name":"Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva","publication_year":2024,"publication_date":"2024-09-02","ids":{"openalex":"https://openalex.org/W4402137264","doi":"https://doi.org/10.26434/chemrxiv-2024-4t52c"},"language":"en","primary_location":{"id":"doi:10.26434/chemrxiv-2024-4t52c","doi":"https://doi.org/10.26434/chemrxiv-2024-4t52c","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2024-4t52c","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.26434/chemrxiv-2024-4t52c","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087840752","display_name":"N. Leigh Anderson","orcid":"https://orcid.org/0000-0003-2699-3998","observed_orcids":["https://orcid.org/0000-0003-2699-3998"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Leigh Anderson","raw_affiliation_strings":["SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039552909","display_name":"A.G. Bailey","orcid":"https://orcid.org/0000-0003-0023-8679","observed_orcids":["https://orcid.org/0000-0003-0023-8679"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alistair Bailey","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068146676","display_name":"Perdita E. Barran","orcid":"https://orcid.org/0000-0002-7720-586X","observed_orcids":["https://orcid.org/0000-0002-7720-586X"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Perdita Barran","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106934433","display_name":"Philip Brownbridge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Philip Brownbridge","raw_affiliation_strings":["Centre for Proteome Research, University of Liverpool, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteome Research, University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101979287","display_name":"Kathleen M. Cain","orcid":"https://orcid.org/0000-0002-1446-5170","observed_orcids":["https://orcid.org/0000-0002-1446-5170"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kathleen Cain","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0002-1446-5170","affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060393064","display_name":"Rachel S. Carling","orcid":"https://orcid.org/0000-0003-1988-3088","observed_orcids":["https://orcid.org/0000-0003-1988-3088"]},"institutions":[{"id":"https://openalex.org/I200166805","display_name":"Guy's and St Thomas' NHS Foundation Trust","ror":"https://ror.org/00j161312","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200166805"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rachel S Carling","raw_affiliation_strings":["Biochemical Sciences, Synnovis, Guys & St Thomas' NHSFT, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemical Sciences, Synnovis, Guys & St Thomas' NHSFT, London, UK","institution_ids":["https://openalex.org/I200166805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016772331","display_name":"Rainer Cramer","orcid":"https://orcid.org/0000-0002-8037-2511","observed_orcids":["https://orcid.org/0000-0002-8037-2511"]},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rainer Cramer","raw_affiliation_strings":["Department of Chemistry, University of Reading, Reading, UK"],"raw_orcid":"https://orcid.org/0000-0002-8037-2511","affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Reading, Reading, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108534756","display_name":"R. Neil Dalton","orcid":"https://orcid.org/0000-0001-9201-5266","observed_orcids":["https://orcid.org/0000-0001-9201-5266"]},"institutions":[{"id":"https://openalex.org/I4210144851","display_name":"Evelina London Children's Healthcare","ror":"https://ror.org/058pgtg13","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200166805","https://openalex.org/I4210144851"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R Neil Dalton","raw_affiliation_strings":["Evelina London Children\u2019s Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evelina London Children\u2019s Hospital, London, UK","institution_ids":["https://openalex.org/I4210144851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065833652","display_name":"Matthew E. Daly","orcid":"https://orcid.org/0000-0001-7795-8477","observed_orcids":["https://orcid.org/0000-0001-7795-8477"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew E Daly","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082355845","display_name":"Kayleigh Davis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200166805","display_name":"Guy's and St Thomas' NHS Foundation Trust","ror":"https://ror.org/00j161312","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200166805"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kayleigh Davis","raw_affiliation_strings":["Biochemical Sciences, Synnovis, Guys & St Thomas' NHSFT, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemical Sciences, Synnovis, Guys & St Thomas' NHSFT, London, UK","institution_ids":["https://openalex.org/I200166805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055233619","display_name":"Ivan Doykov","orcid":"https://orcid.org/0000-0002-4580-6396","observed_orcids":["https://orcid.org/0000-0002-4580-6396"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ivan Doykov","raw_affiliation_strings":["Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028270504","display_name":"Mar\u00eda Emilia Due\u00f1as","orcid":"https://orcid.org/0000-0003-3411-4068","observed_orcids":["https://orcid.org/0000-0003-3411-4068"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maria Emilia Due\u00f1as","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":"https://orcid.org/0000-0003-3411-4068","affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059881489","display_name":"Edward Emmott","orcid":"https://orcid.org/0000-0002-3239-8178","observed_orcids":["https://orcid.org/0000-0002-3239-8178"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Edward Emmott","raw_affiliation_strings":["Centre for Proteome Research, University of Liverpool, Liverpool, UK"],"raw_orcid":"https://orcid.org/0000-0002-3239-8178","affiliations":[{"raw_affiliation_string":"Centre for Proteome Research, University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017388215","display_name":"Claire E. Eyers","orcid":"https://orcid.org/0000-0002-3223-5926","observed_orcids":["https://orcid.org/0000-0002-3223-5926"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Claire E Eyers","raw_affiliation_strings":["Centre for Proteome Research, University of Liverpool, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteome Research, University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075187254","display_name":"Akshada Gajbhiye","orcid":"https://orcid.org/0000-0002-6525-7603","observed_orcids":["https://orcid.org/0000-0002-6525-7603"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Akshada Gajbhiye","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055126440","display_name":"Bethany Geary","orcid":"https://orcid.org/0000-0002-5592-5532","observed_orcids":["https://orcid.org/0000-0002-5592-5532"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bethany Geary","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067560859","display_name":"Pankaj Gupta","orcid":"https://orcid.org/0000-0001-9481-6067","observed_orcids":["https://orcid.org/0000-0001-9481-6067"]},"institutions":[{"id":"https://openalex.org/I2800281165","display_name":"Leicester Royal Infirmary","ror":"https://ror.org/03jkz2y73","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800281165","https://openalex.org/I2802445252"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pankaj Gupta","raw_affiliation_strings":["The Department of Chemical Pathology and Metabolic Diseases, Leicester Royal Infirmary, Leicester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Chemical Pathology and Metabolic Diseases, Leicester Royal Infirmary, Leicester, UK","institution_ids":["https://openalex.org/I2800281165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073106404","display_name":"Jenny H\u00e4llqvist","orcid":"https://orcid.org/0000-0001-6709-3211","observed_orcids":["https://orcid.org/0000-0001-6709-3211"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jenny H\u00e4llqvist","raw_affiliation_strings":["Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044030686","display_name":"Evita Hartmane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Evita Hartmane","raw_affiliation_strings":["Department of Chemistry, University of Reading, Reading, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Reading, Reading, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028735233","display_name":"Simon Heales","orcid":"https://orcid.org/0000-0002-9906-0200","observed_orcids":["https://orcid.org/0000-0002-9906-0200"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Simon Heales","raw_affiliation_strings":["UCL Great Ormond Street Institute of Child Health, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Great Ormond Street Institute of Child Health, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020473108","display_name":"Tiaan D. J. Heunis","orcid":"https://orcid.org/0000-0003-1987-9484","observed_orcids":["https://orcid.org/0000-0003-1987-9484"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tiaan Heunis","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022560693","display_name":"Wendy Heywood","orcid":"https://orcid.org/0000-0003-2106-8760","observed_orcids":["https://orcid.org/0000-0003-2106-8760"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Wendy Heywood","raw_affiliation_strings":["Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036759787","display_name":"Katherine A. Hollywood","orcid":"https://orcid.org/0000-0002-7028-047X","observed_orcids":["https://orcid.org/0000-0002-7028-047X"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Katherine A Hollywood","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048846344","display_name":"Rosalind E. Jenkins","orcid":"https://orcid.org/0000-0002-3730-1136","observed_orcids":["https://orcid.org/0000-0002-3730-1136"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rosalind E Jenkins","raw_affiliation_strings":["CDSS Bioanalytical Facility, University of Liverpool, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CDSS Bioanalytical Facility, University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067262313","display_name":"Donald J. L. Jones","orcid":"https://orcid.org/0000-0001-6583-870X","observed_orcids":["https://orcid.org/0000-0001-6583-870X"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Donald JL Jones","raw_affiliation_strings":["Leicester van Geest Multi-OMICs facility, University of Leicester, Leicester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leicester van Geest Multi-OMICs facility, University of Leicester, Leicester, UK","institution_ids":["https://openalex.org/I153648349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069236946","display_name":"Brian George Keevil","orcid":"https://orcid.org/0000-0002-0684-9318","observed_orcids":["https://orcid.org/0000-0002-0684-9318"]},"institutions":[{"id":"https://openalex.org/I4210092852","display_name":"Manchester University NHS Foundation Trust","ror":"https://ror.org/00he80998","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210092852"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Brian Keevil","raw_affiliation_strings":["Manchester University NHS Foundation Trust, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester University NHS Foundation Trust, Manchester, UK","institution_ids":["https://openalex.org/I4210092852"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031607601","display_name":"Henriette Krenkel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Henriette Krenkel","raw_affiliation_strings":["Department of Chemistry, University of Reading, Reading, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Reading, Reading, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004414447","display_name":"Dan Lane","orcid":"https://orcid.org/0000-0001-9211-2971","observed_orcids":["https://orcid.org/0000-0001-9211-2971"]},"institutions":[{"id":"https://openalex.org/I2800281165","display_name":"Leicester Royal Infirmary","ror":"https://ror.org/03jkz2y73","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800281165","https://openalex.org/I2802445252"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dan Lane","raw_affiliation_strings":["The Department of Chemical Pathology and Metabolic Diseases, Leicester Royal Infirmary, Leicester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Chemical Pathology and Metabolic Diseases, Leicester Royal Infirmary, Leicester, UK","institution_ids":["https://openalex.org/I2800281165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064767405","display_name":"Catherine S. Lane","orcid":"https://orcid.org/0000-0003-2076-3411","observed_orcids":["https://orcid.org/0000-0003-2076-3411"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catherine S Lane","raw_affiliation_strings":["SCIEX, Macclesfield, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SCIEX, Macclesfield, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006090286","display_name":"Sophie E. Lellman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sophie Lellman","raw_affiliation_strings":["Department of Chemistry, University of Reading, Reading, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Reading, Reading, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091032996","display_name":"Ellen Liggett","orcid":"https://orcid.org/0000-0001-6592-0690","observed_orcids":["https://orcid.org/0000-0001-6592-0690"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ellen N Liggett","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0001-6592-0690","affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031753071","display_name":"Xiaoli Meng","orcid":"https://orcid.org/0000-0002-7774-2075","observed_orcids":["https://orcid.org/0000-0002-7774-2075"]},"institutions":[{"id":"https://openalex.org/I146655781","display_name":"University of Liverpool","ror":"https://ror.org/04xs57h96","country_code":"GB","type":"education","lineage":["https://openalex.org/I146655781"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Xiaoli Meng","raw_affiliation_strings":["Dept. of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK","institution_ids":["https://openalex.org/I146655781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035264771","display_name":"Elizabeth N. Clare Mills","orcid":"https://orcid.org/0000-0001-7433-1740","observed_orcids":["https://orcid.org/0000-0001-7433-1740"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Clare Mills","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045744302","display_name":"Kevin A. Mills","orcid":"https://orcid.org/0000-0003-0763-8288","observed_orcids":["https://orcid.org/0000-0003-0763-8288"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kevin Mills","raw_affiliation_strings":["Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034119914","display_name":"Atakan Arda Nalbant","orcid":"https://orcid.org/0000-0002-3705-6601","observed_orcids":["https://orcid.org/0000-0002-3705-6601"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Atakan A Nalbant","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":"https://orcid.org/0000-0002-3705-6601","affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091305818","display_name":"Leong L. Ng","orcid":"https://orcid.org/0000-0002-6553-5749","observed_orcids":["https://orcid.org/0000-0002-6553-5749"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Leong L Ng","raw_affiliation_strings":["Leicester van Geest Multi-OMICs Facility, University of Leicester, Leicester, UK"],"raw_orcid":"https://orcid.org/0000-0002-6553-5749","affiliations":[{"raw_affiliation_string":"Leicester van Geest Multi-OMICs Facility, University of Leicester, Leicester, UK","institution_ids":["https://openalex.org/I153648349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031621453","display_name":"Ben Nicholas","orcid":"https://orcid.org/0000-0003-1467-9643","observed_orcids":["https://orcid.org/0000-0003-1467-9643"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Benjamin Nicholas","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":"https://orcid.org/0000-0003-1467-9643","affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106934432","display_name":"Dan Noels","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dan Noels","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109979209","display_name":"Terry W. Pearson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I212119943","display_name":"University of Victoria","ror":"https://ror.org/04s5mat29","country_code":"CA","type":"education","lineage":["https://openalex.org/I212119943"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Terry W Pearson","raw_affiliation_strings":["SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada","Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada","institution_ids":["https://openalex.org/I212119943"]},{"raw_affiliation_string":"Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada","institution_ids":["https://openalex.org/I212119943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035356657","display_name":"Andrew R. Pitt","orcid":"https://orcid.org/0000-0003-3619-6503","observed_orcids":["https://orcid.org/0000-0003-3619-6503"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Pitt","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073041176","display_name":"Matthew E. Pope","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew E Pope","raw_affiliation_strings":["SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrew Porter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Porter","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038294928","display_name":"George W. Preston","orcid":"https://orcid.org/0000-0003-4812-139X","observed_orcids":["https://orcid.org/0000-0003-4812-139X"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"George W Preston","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0003-4812-139X","affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108254605","display_name":"Morteza Razavi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Morteza Razavi","raw_affiliation_strings":["SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075113571","display_name":"Andrew George Shapanis","orcid":"https://orcid.org/0000-0003-4147-6956","observed_orcids":["https://orcid.org/0000-0003-4147-6956"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Shapanis","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070741568","display_name":"Frances R. Sidgwick","orcid":"https://orcid.org/0000-0001-8792-1096","observed_orcids":["https://orcid.org/0000-0001-8792-1096"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Frances R Sidgwick","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":"https://orcid.org/0000-0001-8792-1096","affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100618640","display_name":"Raj Sukhbir Singh","orcid":"https://orcid.org/0000-0002-1999-4119","observed_orcids":["https://orcid.org/0000-0002-1999-4119"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Raj Singh","raw_affiliation_strings":["Leicester van Geest Multi-OMICS Facility, University of Leicester, Leicester, UK"],"raw_orcid":"https://orcid.org/0000-0002-1999-4119","affiliations":[{"raw_affiliation_string":"Leicester van Geest Multi-OMICS Facility, University of Leicester, Leicester, UK","institution_ids":["https://openalex.org/I153648349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053857955","display_name":"Paul J. S. Skipp","orcid":"https://orcid.org/0000-0002-2995-2959","observed_orcids":["https://orcid.org/0000-0002-2995-2959"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul Skipp","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049687470","display_name":"Reynard Spiess","orcid":"https://orcid.org/0009-0004-4692-9787","observed_orcids":["https://orcid.org/0009-0004-4692-9787"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Reynard Speiss","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0009-0004-4692-9787","affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103867203","display_name":"Justyna \u015apiewak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Justyna Spiewak","raw_affiliation_strings":["Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomics and Genetic Medicine, Great Ormond Street Institute of Child Health, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077814527","display_name":"Anna L. Tierney","orcid":"https://orcid.org/0000-0002-8968-5717","observed_orcids":["https://orcid.org/0000-0002-8968-5717"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna L Tierney","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, and Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Core Technology Facility (3rd Floor), 46 Grafton Street, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0002-8968-5717","affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, and Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Core Technology Facility (3rd Floor), 46 Grafton Street, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089741622","display_name":"Drupad K. Trivedi","orcid":"https://orcid.org/0000-0001-7969-0195","observed_orcids":["https://orcid.org/0000-0001-7969-0195"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Drupad Trivedi","raw_affiliation_strings":["Stoller Biomarker Discovery Centre and Division of Cancer Sciences, The University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre and Division of Cancer Sciences, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000162520","display_name":"Matthias Trost","orcid":"https://orcid.org/0000-0002-5732-700X","observed_orcids":["https://orcid.org/0000-0002-5732-700X"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthias Trost","raw_affiliation_strings":["Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Biological Mass Spectrometry, Newcastle University, Newcastle upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022672574","display_name":"Richard D. Unwin","orcid":"https://orcid.org/0000-0001-7955-9111","observed_orcids":["https://orcid.org/0000-0001-7955-9111"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard D Unwin","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, and Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Core Technology Facility (3rd Floor), 46 Grafton Street, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, and Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Core Technology Facility (3rd Floor), 46 Grafton Street, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078045653","display_name":"Luke Wainwright","orcid":"https://orcid.org/0000-0003-3742-6411","observed_orcids":["https://orcid.org/0000-0003-3742-6411"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Luke Wainwright","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0003-3742-6411","affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051719475","display_name":"Caitlin Walton\u2010Doyle","orcid":"https://orcid.org/0000-0001-7123-3336","observed_orcids":["https://orcid.org/0000-0001-7123-3336"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caitlin Walton-Doyle","raw_affiliation_strings":["Manchester Institute of Biotechnology, University of Manchester, Manchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Institute of Biotechnology, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076360005","display_name":"Anthony David Whetton","orcid":"https://orcid.org/0000-0002-1098-3878","observed_orcids":["https://orcid.org/0000-0002-1098-3878"]},"institutions":[{"id":"https://openalex.org/I2801316944","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2801316944"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210147892","display_name":"CRUK Lung Cancer Centre of Excellence","ror":"https://ror.org/04nm2mq63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210147892"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony D Whetton","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester 9PL; Department of Earth Sciences, University of Oxford, Oxford, UK ; Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK","Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK","Department of Earth Sciences, University of Oxford, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Institute of Cancer Sciences, Faculty of Medical and Human Sciences, University of Manchester, Manchester 9PL; Department of Earth Sciences, University of Oxford, Oxford, UK ; Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK","institution_ids":["https://openalex.org/I2801316944","https://openalex.org/I28407311","https://openalex.org/I40120149"]},{"raw_affiliation_string":"Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK","institution_ids":["https://openalex.org/I2801316944","https://openalex.org/I4210147892"]},{"raw_affiliation_string":"Department of Earth Sciences, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067204485","display_name":"Sandra A. Wilks","orcid":"https://orcid.org/0000-0002-4134-9415","observed_orcids":["https://orcid.org/0000-0002-4134-9415"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sandra Wilks","raw_affiliation_strings":["Centre for Proteomic Research, University of Southampton, Southampton, UK"],"raw_orcid":"https://orcid.org/0000-0002-4134-9415","affiliations":[{"raw_affiliation_string":"Centre for Proteomic Research, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111789595","display_name":"Richard Yip","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Yip","raw_affiliation_strings":["SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SISCAPA Assay Technologies, Inc., Box 53309, Washington, DC 20009, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":15,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.8709999918937683},{"id":"https://openalex.org/keywords/covid-19-diagnosis","display_name":"COVID-19 diagnosis","score":0.8399999737739563},{"id":"https://openalex.org/keywords/antigen-detection","display_name":"antigen detection","score":0.5590000152587891},{"id":"https://openalex.org/keywords/nucleocapsid-protein","display_name":"nucleocapsid protein","score":0.7070000171661377},{"id":"https://openalex.org/keywords/saliva","display_name":"saliva","score":0.43299999833106995},{"id":"https://openalex.org/keywords/lc-ms-ms","display_name":"LC-MS/MS","score":0.7559999823570251},{"id":"https://openalex.org/keywords/clinical-laboratory-testing","display_name":"clinical laboratory testing","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.6525130271911621},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5989104509353638},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5147485733032227},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4688129425048828},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4534655809402466},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.4471144378185272},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40380239486694336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3219679892063141},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2893834710121155},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13393846154212952},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.078998863697052},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0771976113319397},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.26434/chemrxiv-2024-4t52c","doi":"https://doi.org/10.26434/chemrxiv-2024-4t52c","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2024-4t52c","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:pure.atira.dk:openaire/269bf362-cb4c-4fe2-a7fa-bc5511a9ef42","doi":null,"is_oa":true,"landing_page_url":"https://research.manchester.ac.uk/en/publications/269bf362-cb4c-4fe2-a7fa-bc5511a9ef42","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/workingPaper"}],"best_oa_location":{"id":"doi:10.26434/chemrxiv-2024-4t52c","doi":"https://doi.org/10.26434/chemrxiv-2024-4t52c","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2024-4t52c","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320319994","display_name":"Department of Health and Social Care","ror":"https://ror.org/03sbpja79"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1966238900","https://openalex.org/W1987416645","https://openalex.org/W2035037428","https://openalex.org/W2046248204","https://openalex.org/W2117256758","https://openalex.org/W2141091417","https://openalex.org/W2145605402","https://openalex.org/W2200341299","https://openalex.org/W2267583510","https://openalex.org/W3004280078","https://openalex.org/W3009912996","https://openalex.org/W3010223921","https://openalex.org/W3014744264","https://openalex.org/W3016610966","https://openalex.org/W3018072231","https://openalex.org/W3029424699","https://openalex.org/W3036361557","https://openalex.org/W3048795936","https://openalex.org/W3082786414","https://openalex.org/W3085648521","https://openalex.org/W3110538225","https://openalex.org/W3126758556","https://openalex.org/W3143867892","https://openalex.org/W3151746440","https://openalex.org/W3158736959","https://openalex.org/W3172599793","https://openalex.org/W3208220511","https://openalex.org/W3211420494","https://openalex.org/W3212648179","https://openalex.org/W4213419305","https://openalex.org/W4214830881","https://openalex.org/W4283207765","https://openalex.org/W4285087832","https://openalex.org/W4294376416","https://openalex.org/W4309202427","https://openalex.org/W4362609000","https://openalex.org/W4382797336","https://openalex.org/W4391365483","https://openalex.org/W4396693311","https://openalex.org/W4401461906"],"related_works":["https://openalex.org/W3125325049","https://openalex.org/W4211051726","https://openalex.org/W3211420494","https://openalex.org/W4214830881","https://openalex.org/W3181429454","https://openalex.org/W3044855186","https://openalex.org/W4200517531","https://openalex.org/W4309202427","https://openalex.org/W3048849008","https://openalex.org/W4399721664"],"abstract_inverted_index":{"During":[0],"the":[1,12,17,20,105,114,125,133,145,167,193],"COVID-19":[2],"pandemic,":[3],"development":[4],"of":[5,19,26,50,91,104,144,164,178,197],"diagnostic":[6],"tests":[7],"was":[8],"vital":[9],"to":[10,15,33,39,69,85,124,202],"chart":[11],"course":[13],"and":[14,24,77,88,93,116,156,162,195,205],"reduce":[16],"impact":[18],"infection.":[21],"Continued":[22],"testing":[23,42],"surveillance":[25],"vaccine":[27],"escape":[28],"will":[29],"continue":[30],"for":[31,59,127,132,138],"years":[32],"come":[34],"which":[35],"presents":[36],"an":[37,108,176],"opportunity":[38],"integrate":[40],"such":[41],"into":[43],"clinical":[44],"biochemistry":[45],"laboratories":[46],"that":[47],"form":[48],"part":[49],"integrated":[51],"healthcare":[52],"testing.":[53],"Here":[54],"we":[55],"describe":[56],"a":[57,60,152,171],"protocol":[58],"targeted":[61],"mass":[62],"spectrometry":[63],"based":[64],"proteomic":[65],"assay":[66,134,174],"(COVIDCAP)":[67],"developed":[68],"detect":[70],"SARS-CoV-2":[71,95],"peptides":[72,165],"from":[73,166,181],"oro-nasopharyngeal":[74],"swabs":[75],"(ONP)":[76],"saliva.":[78],"This":[79,111],"uses":[80],"novel":[81],"SISCAPA":[82],"antibodies":[83],"bound":[84],"magnetic":[86],"beads":[87],"subsequent":[89,157],"analysis":[90,199],"captured":[92],"purified":[94],"nucleocapsid":[96],"(NCAP)":[97],"peptides.":[98],"The":[99],"method":[100],"involves":[101],"immediate":[102],"deactivation":[103],"sample":[106],"using":[107],"ethanolic":[109],"solution.":[110],"simultaneously":[112],"inactivates":[113],"virus":[115],"denatures":[117],"viral":[118],"proteins":[119],"at":[120],"sampling":[121],"in":[122,170],"contrast":[123],"approach":[126],"RT-PCR":[128],"testing,":[129],"with":[130,175],"benefits":[131],"as":[135,137,190],"well":[136],"downstream":[139],"processing.":[140],"A":[141],"plate-based":[142],"preparation":[143],"samples":[146,188],"involving":[147],"acetone":[148],"precipitation":[149],"followed":[150],"by":[151],"short":[153],"tryptic":[154],"digestion":[155],"immunocapture":[158],"allows":[159],"LC-MS":[160],"detection":[161],"quantification":[163],"NCAP":[168],"protein,":[169],"3-minute":[172],"inject-to-inject":[173],"LOD":[177],"20":[179],"attomoles":[180],"starting":[182],"sample.":[183],"For":[184],"576":[185],"ONP":[186],"swab":[187],"taken":[189],"exemplars":[191],"here,":[192],"sensitivity":[194],"specificity":[196],"this":[198],"is":[200],"shown":[201],"be":[203],"97.0%":[204],"96.6%":[206],"respectively.":[207]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-09-03T00:00:00"}
