{"id":"https://openalex.org/W4402057714","doi":"https://doi.org/10.1038/s41589-024-01721-2","title":"\u00b5Map proximity labeling in living cells reveals stress granule disassembly mechanisms","display_name":"\u00b5Map proximity labeling in living cells reveals stress granule disassembly mechanisms","publication_year":2024,"publication_date":"2024-08-30","ids":{"openalex":"https://openalex.org/W4402057714","doi":"https://doi.org/10.1038/s41589-024-01721-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/39215100","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11868469"},"language":"en","primary_location":{"id":"doi:10.1038/s41589-024-01721-2","doi":"https://doi.org/10.1038/s41589-024-01721-2","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41589-024-01721-2","pdf_url":null,"source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11868469/pdf/nihms-2049009.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022250942","display_name":"Chenmengxiao Pan","orcid":"https://orcid.org/0009-0002-7990-424X","observed_orcids":["https://orcid.org/0009-0002-7990-424X"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chenmengxiao Pan","raw_affiliation_strings":["Department of Chemistry, Princeton University, Princeton, NJ, USA","Merck Center for Catalysis at Princeton University, Princeton, NJ, USA"],"raw_orcid":"https://orcid.org/0009-0002-7990-424X","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Merck Center for Catalysis at Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080580705","display_name":"Steve D. Knutson","orcid":"https://orcid.org/0000-0001-6822-464X","observed_orcids":["https://orcid.org/0000-0001-6822-464X"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve D. Knutson","raw_affiliation_strings":["Department of Chemistry, Princeton University, Princeton, NJ, USA","Merck Center for Catalysis at Princeton University, Princeton, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Merck Center for Catalysis at Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039315630","display_name":"Sean W. Huth","orcid":"https://orcid.org/0000-0002-4892-2587","observed_orcids":["https://orcid.org/0000-0002-4892-2587"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean W. Huth","raw_affiliation_strings":["Department of Chemistry, Princeton University, Princeton, NJ, USA","Merck Center for Catalysis at Princeton University, Princeton, NJ, USA"],"raw_orcid":"https://orcid.org/0000-0002-4892-2587","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Merck Center for Catalysis at Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025805979","display_name":"David W. C. MacMillan","orcid":"https://orcid.org/0000-0001-6447-0587","observed_orcids":["https://orcid.org/0000-0001-6447-0587"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David W. C. MacMillan","raw_affiliation_strings":["Department of Chemistry, Princeton University, Princeton, NJ, USA. dmacmill@princeton.edu","Merck Center for Catalysis at Princeton University, Princeton, NJ, USA. dmacmill@princeton.edu","Department of Chemistry, Princeton University, Princeton, NJ, USA"],"raw_orcid":"https://orcid.org/0000-0001-6447-0587","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Princeton University, Princeton, NJ, USA. dmacmill@princeton.edu","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Merck Center for Catalysis at Princeton University, Princeton, NJ, USA. dmacmill@princeton.edu","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Department of Chemistry, Princeton University, Princeton, NJ, USA","institution_ids":["https://openalex.org/I20089843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025805979"],"corresponding_institution_ids":["https://openalex.org/I20089843"],"apc_list":{"value":12290,"currency":"USD","value_usd":12290},"apc_paid":null,"fwci":17.2263,"has_fulltext":true,"cited_by_count":76,"citation_normalized_percentile":{"value":0.99778975,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"21","issue":"4","first_page":"490","last_page":"500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies","score":0.9419000148773193,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies","score":0.9419000148773193,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stress-granules","display_name":"stress granules","score":0.9850000143051147},{"id":"https://openalex.org/keywords/stress-granule-disassembly","display_name":"stress granule disassembly","score":0.859000027179718},{"id":"https://openalex.org/keywords/phase-separated-condensates","display_name":"phase-separated condensates","score":0.8109999895095825},{"id":"https://openalex.org/keywords/halotag","display_name":"HaloTag","score":0.5730000138282776},{"id":"https://openalex.org/keywords/e3-ubiquitin-ligase","display_name":"E3 ubiquitin ligase","score":0.7620000243186951},{"id":"https://openalex.org/keywords/pruritus","display_name":"pruritus","score":0.8650000095367432},{"id":"https://openalex.org/keywords/nedd4l","display_name":"NEDD4L","score":1.0},{"id":"https://openalex.org/keywords/tollip","display_name":"Tollip","score":0.9470000267028809},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.9380000233650208},{"id":"https://openalex.org/keywords/biomolecular-condensates","display_name":"biomolecular condensates","score":0.781000018119812},{"id":"https://openalex.org/keywords/protein-protein-interaction-network","display_name":"protein-protein interaction network","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C117838200","wikidata":"https://www.wikidata.org/wiki/Q14592582","display_name":"Stress granule","level":5,"score":0.6411202549934387},{"id":"https://openalex.org/C49760210","wikidata":"https://www.wikidata.org/wiki/Q5596727","display_name":"Granule (geology)","level":2,"score":0.5432941913604736},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.491806298494339},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4791138172149658},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.41904211044311523},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39468914270401},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3434189260005951},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3024798035621643},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1997145116329193},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1904512643814087},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0673736035823822},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000088162","descriptor_name":"Stress Granules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41589-024-01721-2","doi":"https://doi.org/10.1038/s41589-024-01721-2","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41589-024-01721-2","pdf_url":null,"source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},{"id":"pmid:39215100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39215100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature chemical biology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:10768401","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11868469","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11868469/pdf/nihms-2049009.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:11868469","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11868469","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Chem Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:10768401","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11868469","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11868469/pdf/nihms-2049009.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1340549388","display_name":null,"funder_award_id":"R35GM134897","funder_id":"https://openalex.org/F4320337544","funder_display_name":"Office of Extramural Research, National Institutes of Health"},{"id":"https://openalex.org/G4148540197","display_name":null,"funder_award_id":"R35GM134897","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G5535053253","display_name":"High-Resolution Mapping of Subcellular RNA Dynamics Using Photocatalytic Proximity Labeling","funder_award_id":"F32GM142206","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7837136041","display_name":null,"funder_award_id":"1F32GM142206-01","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G8789817137","display_name":null,"funder_award_id":"1F32GM142206-01","funder_id":"https://openalex.org/F4320337544","funder_display_name":"Office of Extramural Research, National Institutes of Health"},{"id":"https://openalex.org/G9000864345","display_name":"Mechanistic Interrogation of Long Non-coding RNAs using Photocatalytic Proximity Labeling and CRISPR Phenotypic Profiling","funder_award_id":"K99GM154140","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000912975","display_name":"Photoredox Catalysis Applications in Organometallics and Chemical Biology","funder_award_id":"R35GM134897","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320309292","display_name":"Princeton University","ror":"https://ror.org/00hx57361"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337415","display_name":"Janssen Research and Development","ror":"https://ror.org/03qd7mz70"},{"id":"https://openalex.org/F4320337544","display_name":"Office of Extramural Research, National Institutes of Health","ror":"https://ror.org/05aq6yn88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402057714.pdf","grobid_xml":"https://content.openalex.org/works/W4402057714.grobid-xml"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W1998340446","https://openalex.org/W2004250476","https://openalex.org/W2007400675","https://openalex.org/W2039778506","https://openalex.org/W2044821390","https://openalex.org/W2048494900","https://openalex.org/W2066107559","https://openalex.org/W2076544864","https://openalex.org/W2091332165","https://openalex.org/W2124420768","https://openalex.org/W2134178604","https://openalex.org/W2150860983","https://openalex.org/W2158368342","https://openalex.org/W2161594732","https://openalex.org/W2236156346","https://openalex.org/W2368986416","https://openalex.org/W2416403255","https://openalex.org/W2463195069","https://openalex.org/W2514004327","https://openalex.org/W2537738364","https://openalex.org/W2556818673","https://openalex.org/W2590568317","https://openalex.org/W2608925462","https://openalex.org/W2767613320","https://openalex.org/W2783151804","https://openalex.org/W2784370070","https://openalex.org/W2784401093","https://openalex.org/W2801471302","https://openalex.org/W2886290321","https://openalex.org/W2890499152","https://openalex.org/W2910213537","https://openalex.org/W2927034536","https://openalex.org/W2928665623","https://openalex.org/W2937251669","https://openalex.org/W2950827955","https://openalex.org/W2977383991","https://openalex.org/W2991106430","https://openalex.org/W3010320439","https://openalex.org/W3016592635","https://openalex.org/W3017159371","https://openalex.org/W3026751717","https://openalex.org/W3033323818","https://openalex.org/W3033695247","https://openalex.org/W3089848576","https://openalex.org/W3106401261","https://openalex.org/W3123064828","https://openalex.org/W3133726503","https://openalex.org/W3164735937","https://openalex.org/W3169371629","https://openalex.org/W3173550943","https://openalex.org/W3174082797","https://openalex.org/W3174904045","https://openalex.org/W3176820067","https://openalex.org/W4220659847","https://openalex.org/W4221117452","https://openalex.org/W4281558609","https://openalex.org/W4281569188","https://openalex.org/W4283159995","https://openalex.org/W4284676017","https://openalex.org/W4284897468","https://openalex.org/W4289261816","https://openalex.org/W4291804711","https://openalex.org/W4294091366","https://openalex.org/W4311825265","https://openalex.org/W4317870345","https://openalex.org/W4319077765","https://openalex.org/W4362602997","https://openalex.org/W4367311935","https://openalex.org/W4382395839","https://openalex.org/W4384925259","https://openalex.org/W4387996891","https://openalex.org/W4388413365","https://openalex.org/W4388694325"],"related_works":["https://openalex.org/W3008140494","https://openalex.org/W7128170229","https://openalex.org/W4409247543","https://openalex.org/W7161027969","https://openalex.org/W4213353800","https://openalex.org/W4405662038","https://openalex.org/W4389043167","https://openalex.org/W7159687979","https://openalex.org/W7116953097","https://openalex.org/W7135336716"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":39},{"year":2025,"cited_by_count":32},{"year":2024,"cited_by_count":5}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2024-08-31T00:00:00"}