{"id":"https://openalex.org/W4402012777","doi":"https://doi.org/10.6019/empiar-11711","title":"Cryo-EM micrographs of human DNA polymerase \u03b8 helicase domain bound to inhibitor AB25583","display_name":"Cryo-EM micrographs of human DNA polymerase \u03b8 helicase domain bound to inhibitor AB25583","publication_year":2023,"publication_date":"2023-09-18","ids":{"openalex":"https://openalex.org/W4402012777","doi":"https://doi.org/10.6019/empiar-11711"},"language":"en","primary_location":{"id":"doi:10.6019/empiar-11711","doi":"https://doi.org/10.6019/empiar-11711","is_oa":true,"landing_page_url":"http://dx.doi.org/10.6019/empiar-11711","pdf_url":null,"source":{"id":"https://openalex.org/S4363605424","display_name":"EMPIAR dataset","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMPIAR dataset","raw_type":"dataset"},"volume":null,"type":"dataset","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://dx.doi.org/10.6019/empiar-11711","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062506748","display_name":"Fumiaki Ito","orcid":"https://orcid.org/0000-0002-2274-118X","observed_orcids":["https://orcid.org/0000-0002-2274-118X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ito F","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2274-118X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100415193","display_name":"Zhijian Li","orcid":"https://orcid.org/0000-0002-1523-1333","observed_orcids":["https://orcid.org/0000-0002-1523-1333"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li Z","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029887812","display_name":"\u041c\u0438\u043d\u0430\u0445\u0438\u043d \u041b\u0435\u043e\u043d\u0438\u0434 \u0421\u0442\u0430\u043d\u0438\u0441\u043b\u0430\u0432\u043e\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0003-0301-7054","observed_orcids":["https://orcid.org/0000-0003-0301-7054"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Minakhin L","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026651627","display_name":"Gurushankar Chandramouly","orcid":"https://orcid.org/0000-0002-4258-9859","observed_orcids":["https://orcid.org/0000-0002-4258-9859"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chandramouly G","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Tyagi M","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tyagi M","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093330872","display_name":"Robert G. Betsch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Betsch R","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085528587","display_name":"John J. Krais","orcid":"https://orcid.org/0000-0002-3916-3435","observed_orcids":["https://orcid.org/0000-0002-3916-3435"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krais JJ","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093653773","display_name":"Bernadette Tiberi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tiberi B","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Johnson N","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johnson N","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113288670","display_name":"Chen XS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chen XS","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5082223399","display_name":"Richard T. Pomerantz","orcid":"https://orcid.org/0000-0003-1194-9871","observed_orcids":["https://orcid.org/0000-0003-1194-9871"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pomerantz RT","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.420199990272522,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.420199990272522,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.32420000433921814,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.17550000548362732,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-polymerase-theta","display_name":"DNA polymerase theta","score":0.8690000176429749},{"id":"https://openalex.org/keywords/helicase-domain","display_name":"helicase domain","score":0.9940000176429749},{"id":"https://openalex.org/keywords/inhibitor-binding","display_name":"inhibitor binding","score":0.652999997138977},{"id":"https://openalex.org/keywords/protein-inhibitor-complex","display_name":"protein-inhibitor complex","score":0.7720000147819519},{"id":"https://openalex.org/keywords/dna-replication","display_name":"DNA replication","score":0.4189999997615814},{"id":"https://openalex.org/keywords/cryo-electron-microscopy","display_name":"cryo-electron microscopy","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C161223559","wikidata":"https://www.wikidata.org/wiki/Q138864","display_name":"Helicase","level":4,"score":0.6341714859008789},{"id":"https://openalex.org/C82381507","wikidata":"https://www.wikidata.org/wiki/Q416878","display_name":"Polymerase","level":3,"score":0.5446902513504028},{"id":"https://openalex.org/C2756471","wikidata":"https://www.wikidata.org/wiki/Q206286","display_name":"DNA polymerase","level":3,"score":0.4813997745513916},{"id":"https://openalex.org/C3018767501","wikidata":"https://www.wikidata.org/wiki/Q130416","display_name":"Electron micrographs","level":3,"score":0.4606059193611145},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.41327226161956787},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3948919177055359},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3394838869571686},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3261395990848541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3191603422164917},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.23427847027778625},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20809215307235718},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14913800358772278},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.10049259662628174},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.055606842041015625},{"id":"https://openalex.org/C93877712","wikidata":"https://www.wikidata.org/wiki/Q132560","display_name":"Electron microscope","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.6019/empiar-11711","doi":"https://doi.org/10.6019/empiar-11711","is_oa":true,"landing_page_url":"http://dx.doi.org/10.6019/empiar-11711","pdf_url":null,"source":{"id":"https://openalex.org/S4363605424","display_name":"EMPIAR dataset","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMPIAR dataset","raw_type":"dataset"}],"best_oa_location":{"id":"doi:10.6019/empiar-11711","doi":"https://doi.org/10.6019/empiar-11711","is_oa":true,"landing_page_url":"http://dx.doi.org/10.6019/empiar-11711","pdf_url":null,"source":{"id":"https://openalex.org/S4363605424","display_name":"EMPIAR dataset","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMPIAR dataset","raw_type":"dataset"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6926288287","https://openalex.org/W6963591090","https://openalex.org/W4410235435","https://openalex.org/W4412172468","https://openalex.org/W2995519603","https://openalex.org/W6958748876","https://openalex.org/W6907777367","https://openalex.org/W2995890430","https://openalex.org/W6964110231","https://openalex.org/W6963893608"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2024-08-30T00:00:00"}