{"id":"https://openalex.org/W4401919986","doi":"https://doi.org/10.1192/j.eurpsy.2024.1417","title":"Cerebral-cognitive reserve: concept and functions of the cerebral-cognitive reserve","display_name":"Cerebral-cognitive reserve: concept and functions of the cerebral-cognitive reserve","publication_year":2024,"publication_date":"2024-04-01","ids":{"openalex":"https://openalex.org/W4401919986","doi":"https://doi.org/10.1192/j.eurpsy.2024.1417","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11860335"},"language":"en","primary_location":{"id":"doi:10.1192/j.eurpsy.2024.1417","doi":"https://doi.org/10.1192/j.eurpsy.2024.1417","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2024.1417","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/349DEC08B5CF9925CC702F8699DA5E98/S0924933824014172a.pdf/div-class-title-cerebral-cognitive-reserve-concept-and-functions-of-the-cerebral-cognitive-reserve-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/349DEC08B5CF9925CC702F8699DA5E98/S0924933824014172a.pdf/div-class-title-cerebral-cognitive-reserve-concept-and-functions-of-the-cerebral-cognitive-reserve-div.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082442629","display_name":"Alena Petrovna Sidenkova","orcid":"https://orcid.org/0000-0001-5142-3992","observed_orcids":["https://orcid.org/0000-0001-5142-3992"]},"institutions":[{"id":"https://openalex.org/I4210093938","display_name":"Ural State Medical University","ror":"https://ror.org/00fycgp36","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210093938"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"A. Sidenkova","raw_affiliation_strings":["Psychiatry, Ural State Medical University, Yekaterinburg, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ural State Medical University, Yekaterinburg, Russian Federation","institution_ids":["https://openalex.org/I4210093938"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5082442629"],"corresponding_institution_ids":["https://openalex.org/I4210093938"],"apc_list":{"value":3150,"currency":"USD","value_usd":3150},"apc_paid":{"value":3150,"currency":"USD","value_usd":3150},"fwci":0.4475,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.59450777,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"67","issue":"S1","first_page":"S681","last_page":"S682"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10465","display_name":"Neurobiology of Language and Bilingualism","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cognitive-reserve","display_name":"cognitive reserve","score":0.9760000109672546},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9919999837875366},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.6399999856948853},{"id":"https://openalex.org/keywords/brain-vulnerability","display_name":"brain vulnerability","score":0.5740000009536743},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.7260000109672546},{"id":"https://openalex.org/keywords/dementia-risk","display_name":"dementia risk","score":0.890999972820282},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.5690000057220459},{"id":"https://openalex.org/keywords/compensatory-mechanisms","display_name":"compensatory mechanisms","score":0.7049999833106995},{"id":"https://openalex.org/keywords/brain-atrophy","display_name":"brain atrophy","score":0.5370000004768372},{"id":"https://openalex.org/keywords/preclinical-alzheimer-s-disease","display_name":"preclinical Alzheimer's disease","score":0.7210000157356262},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.41600000858306885},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C67739388","wikidata":"https://www.wikidata.org/wiki/Q579471","display_name":"Cognitive reserve","level":4,"score":0.8887128829956055},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5948526263237},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41233232617378235},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.32026195526123047},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.30279117822647095},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.19582751393318176}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1192/j.eurpsy.2024.1417","doi":"https://doi.org/10.1192/j.eurpsy.2024.1417","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2024.1417","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/349DEC08B5CF9925CC702F8699DA5E98/S0924933824014172a.pdf/div-class-title-cerebral-cognitive-reserve-concept-and-functions-of-the-cerebral-cognitive-reserve-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11860335","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11860335","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11860335/pdf/S0924933824014172a.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur Psychiatry","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:decf68606faa40c0a800be3c452cc08c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/decf68606faa40c0a800be3c452cc08c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Psychiatry, Vol 67, Pp S681-S682 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1192/j.eurpsy.2024.1417","doi":"https://doi.org/10.1192/j.eurpsy.2024.1417","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2024.1417","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/349DEC08B5CF9925CC702F8699DA5E98/S0924933824014172a.pdf/div-class-title-cerebral-cognitive-reserve-concept-and-functions-of-the-cerebral-cognitive-reserve-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401919986.pdf","grobid_xml":"https://content.openalex.org/works/W4401919986.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4401934160","https://openalex.org/W2028453477","https://openalex.org/W4401935095","https://openalex.org/W2117971276","https://openalex.org/W2346084410","https://openalex.org/W2917268948","https://openalex.org/W2733553215","https://openalex.org/W4321599477","https://openalex.org/W7221096672","https://openalex.org/W2908877869"],"abstract_inverted_index":{"Introduction":[0],"The":[1,39,63,103,140,258,291,314],"modern":[2],"understanding":[3],"of":[4,14,18,25,41,49,54,60,65,73,97,118,123,133,145,153,168,181,195,205,221,253,261,272,316,322,328,337,358,366,369,375],"AD":[5,218,265,296,370],"allows":[6],"us":[7],"to":[8,69,76,111,345],"consider":[9],"it":[10],"through":[11,115,172],"the":[12,19,29,33,52,58,71,74,95,124,166,179,186,193,222,251,273,280,304,320,323,333,335,338,340,347,349,355,359,364],"constructs":[13],"\u201cvulnerability\u201d":[15],"and":[16,32,57,267,285,288,295,342],"\u201cstability\u201d":[17],"brain":[20,55,75,98,125,127,196,223,305],"as":[21,89,108,250],"a":[22,77,82,90,225,269],"dynamic":[23],"system":[24],"dialectical":[26],"interaction":[27],"between":[28,51,282,293],"pathogenic":[30],"process":[31,35],"protective":[34,91,244,259],"that":[36,93,211],"prevents":[37],"neurodegeneration.":[38],"concept":[40,64,315],"cognitive":[42,101,113,157,201,230,289,329,372],"reserve":[43,318],"(CR)":[44],"is":[45],"based":[46],"on":[47,100,156,178,246],"observations":[48],"discrepancy":[50],"degree":[53],"pathology":[56,99,197,297],"severity":[59],"clinical":[61,247],"manifestations.":[62],"\u201creserve\u201d":[66],"was":[67],"proposed":[68],"describe":[70],"resistance":[72],"developing":[78],"damage":[79],"caused":[80],"by":[81],"pathological":[83,183],"process.":[84],"Stern":[85],"(2002)":[86],"considered":[87],"CR":[88,107,154,163,189,236,243,262,278,312],"factor":[92,228],"modifies":[94],"impact":[96],"function.":[102],"researchers":[104],"have":[105,159],"defined":[106],"an":[109,143],"ability":[110],"optimize":[112],"function":[114],"differential":[116],"involvement":[117],"structures":[119],"or":[120,170,198,203,214,299],"neural":[121],"networks":[122],"into":[126,371],"activity.":[128],"Objectives":[129],"A":[130],"systematic":[131],"review":[132,141],"scientific":[134],"studies":[135],"has":[136,208],"been":[137,160,209],"conducted":[138],"Methods":[139],"includes":[142],"analysis":[144],"full-text":[146],"literature":[147],"sources.":[148],"Results":[149],"Several":[150],"possible":[151],"directions":[152],"influence":[155],"functions":[158],"described:":[161],"1)":[162],"may":[164,306],"reduce":[165,249],"risk":[167,204,227],"MCI":[169],"dementia":[171],"mechanisms,":[173],"which":[174,361],"do":[175],"not":[176],"depend":[177],"level":[180,298],"neurodegenerative":[182],"changes":[184,279,302],"in":[185,216,232,238,303,308,331],"brain.":[187],"2)":[188],"can":[190,362],"interact":[191],"with":[192,234,240,310],"markers":[194],"healthaffectingthe":[199],"future":[200],"decline":[202],"progression.":[206],"It":[207],"found":[210],"smaller":[212],"volumes":[213],"thickness":[215],"some":[217],"vulnerable":[219],"areas":[220],"represent":[224],"stronger":[226],"for":[229,325],"impairment":[231],"people":[233,239,309],"low":[235,270],"than":[237],"higher":[241,311],"CR.":[242],"effects":[245],"outcomes":[248],"number":[252],"damaged":[254,274],"neurons":[255],"increases.":[256],"3)":[257],"effect":[260],"increasesduring":[263],"late":[264],"onset":[266],"at":[268],"rate":[271],"substrate":[275],"accumulation.":[276],"4)":[277],"relationship":[281,292],"genetic":[283],"factors":[284],"aging":[286],"withclinical":[287],"outcomes.":[290],"age":[294],"age-related":[300],"structural":[301],"weaken":[307],"Conclusions":[313],"cerebral-cognitive":[317],"actualizes":[319],"problem":[321],"search":[324],"compensatory":[326],"mechanisms":[327],"deficit":[330],"AD,":[332],"assessmentof":[334],"structure":[336],"reserve,":[339,348],"development":[341],"implementationof":[343],"programs":[344],"maintain":[346],"preventionof":[350],"its":[351],"depletion,":[352],"starting":[353],"from":[354],"preclinical":[356,367],"stage":[357],"disease,":[360],"prevent":[363],"transformation":[365],"manifestations":[368],"disorders":[373],"Disclosure":[374],"Interest":[376],"None":[377],"Declared":[378]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2024-08-28T00:00:00"}