{"id":"https://openalex.org/W4401894698","doi":"https://doi.org/10.3390/ijms25169120","title":"Elucidating Chiral Resolution of Aromatic Amino Acids Using Glycopeptide Selectors: A Combined Molecular Docking and Chromatographic Study","display_name":"Elucidating Chiral Resolution of Aromatic Amino Acids Using Glycopeptide Selectors: A Combined Molecular Docking and Chromatographic Study","publication_year":2024,"publication_date":"2024-08-22","ids":{"openalex":"https://openalex.org/W4401894698","doi":"https://doi.org/10.3390/ijms25169120","pmid":"https://pubmed.ncbi.nlm.nih.gov/39201804","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11354492"},"language":"en","primary_location":{"id":"doi:10.3390/ijms25169120","doi":"https://doi.org/10.3390/ijms25169120","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25169120","pdf_url":"https://www.mdpi.com/1422-0067/25/16/9120/pdf?version=1724327398","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/25/16/9120/pdf?version=1724327398","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013014374","display_name":"Dehbiya Gherdaoui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128965","display_name":"University Yahia Fares of Medea","ror":"https://ror.org/02e2yc259","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210128965"]},{"id":"https://openalex.org/I4210133935","display_name":"\u00c9cole Normale Sup\u00e9rieure de Kouba","ror":"https://ror.org/03kh2rb68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210133935"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Dehbiya Gherdaoui","raw_affiliation_strings":["Higher Normal School, Laboratory of Research on Bio-Active Products and Valorization of Biomasse, Old-Kouba, Algiers 16050, Algeria","Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Higher Normal School, Laboratory of Research on Bio-Active Products and Valorization of Biomasse, Old-Kouba, Algiers 16050, Algeria","institution_ids":["https://openalex.org/I4210133935"]},{"raw_affiliation_string":"Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002389647","display_name":"Madiha Melha Yahoum","orcid":"https://orcid.org/0000-0002-7204-8260","observed_orcids":["https://orcid.org/0000-0002-7204-8260"]},"institutions":[{"id":"https://openalex.org/I4210128965","display_name":"University Yahia Fares of Medea","ror":"https://ror.org/02e2yc259","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210128965"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Madiha Melha Yahoum","raw_affiliation_strings":["Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","Materials and Environmental Laboratory (LME), University of Medea, New Urban Pole, Medea 26000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]},{"raw_affiliation_string":"Materials and Environmental Laboratory (LME), University of Medea, New Urban Pole, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002864567","display_name":"Selma Toumi","orcid":"https://orcid.org/0000-0002-1569-8195","observed_orcids":["https://orcid.org/0000-0002-1569-8195"]},"institutions":[{"id":"https://openalex.org/I4210128965","display_name":"University Yahia Fares of Medea","ror":"https://ror.org/02e2yc259","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210128965"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Selma Toumi","raw_affiliation_strings":["Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060574366","display_name":"Sabrina Lekmine","orcid":"https://orcid.org/0000-0002-4945-7170","observed_orcids":["https://orcid.org/0000-0002-4945-7170"]},"institutions":[{"id":"https://openalex.org/I4210130929","display_name":"Abb\u00e8s Laghrour University of Khenchela","ror":"https://ror.org/02yyskm09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210130929"]}],"countries":["DZ"],"is_corresponding":true,"raw_author_name":"Sabrina Lekmine","raw_affiliation_strings":["Biotechnology, Water, Environment and Health Laboratory, Abbes Laghrour University, Khenchela 40000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnology, Water, Environment and Health Laboratory, Abbes Laghrour University, Khenchela 40000, Algeria","institution_ids":["https://openalex.org/I4210130929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019062327","display_name":"Sonia Lefnaoui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128965","display_name":"University Yahia Fares of Medea","ror":"https://ror.org/02e2yc259","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210128965"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Sonia Lefnaoui","raw_affiliation_strings":["Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003969428","display_name":"Ouided Benslama","orcid":"https://orcid.org/0000-0002-7946-219X","observed_orcids":["https://orcid.org/0000-0002-7946-219X"]},"institutions":[{"id":"https://openalex.org/I3132180716","display_name":"Larbi Ben M'hidi University of Oum El Bouaghi","ror":"https://ror.org/0034tbg85","country_code":"DZ","type":"education","lineage":["https://openalex.org/I3132180716"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Ouided Benslama","raw_affiliation_strings":["Laboratory of Natural Substances, Biomolecules and Biotechnological Applications, Department of Natural and Life Sciences, Larbi Ben M\u2019Hidi University, Oum El Bouaghi 04000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Natural Substances, Biomolecules and Biotechnological Applications, Department of Natural and Life Sciences, Larbi Ben M\u2019Hidi University, Oum El Bouaghi 04000, Algeria","institution_ids":["https://openalex.org/I3132180716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057601960","display_name":"Rachida Bouallouche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157169809","display_name":"University of Sciences and Technology Houari Boumediene","ror":"https://ror.org/02kb89c09","country_code":"DZ","type":"education","lineage":["https://openalex.org/I157169809"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Rachida Bouallouche","raw_affiliation_strings":["Reaction Engineering Laboratory, Faculty of Mechanical and Process Engineering, University of Science and Technology Houari Boumediene, BP32 El Alia, Bab Ezzouar, Algiers 16111, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Reaction Engineering Laboratory, Faculty of Mechanical and Process Engineering, University of Science and Technology Houari Boumediene, BP32 El Alia, Bab Ezzouar, Algiers 16111, Algeria","institution_ids":["https://openalex.org/I157169809"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004124007","display_name":"Hichem Tahraoui","orcid":"https://orcid.org/0000-0003-2209-6405","observed_orcids":["https://orcid.org/0000-0003-2209-6405"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I40193446","display_name":"University Ferhat Abbas of Setif","ror":"https://ror.org/02rzqza52","country_code":"DZ","type":"education","lineage":["https://openalex.org/I40193446"]},{"id":"https://openalex.org/I4210090783","display_name":"Institut des Sciences Chimiques de Rennes","ror":"https://ror.org/00adwkx90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I28221208","https://openalex.org/I4210090783","https://openalex.org/I4210115835","https://openalex.org/I4210128300","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I4210128965","display_name":"University Yahia Fares of Medea","ror":"https://ror.org/02e2yc259","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210128965"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["DZ","FR"],"is_corresponding":false,"raw_author_name":"Hichem Tahraoui","raw_affiliation_strings":["Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","Laboratory of Chemical Process Engineering, Department of Process Engineering, Faculty of Technology, Ferhat Abbas University, Setif-1, Setif 19000, Algeria","National Higher School of Chemistry of Rennes, Scientific Research National Center (CNRS), Rennes Institute of Chemical Sciences\u2014Mixed Research Unit (ISCR\u2014UMR6226), Rennes University, 35000 Rennes, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomaterials and Transport Phenomena (LBMPT), New Urban Pole, Medea University, Medea 26000, Algeria","institution_ids":["https://openalex.org/I4210128965"]},{"raw_affiliation_string":"Laboratory of Chemical Process Engineering, Department of Process Engineering, Faculty of Technology, Ferhat Abbas University, Setif-1, Setif 19000, Algeria","institution_ids":["https://openalex.org/I40193446"]},{"raw_affiliation_string":"National Higher School of Chemistry of Rennes, Scientific Research National Center (CNRS), Rennes Institute of Chemical Sciences\u2014Mixed Research Unit (ISCR\u2014UMR6226), Rennes University, 35000 Rennes, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210090783","https://openalex.org/I56067802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049683535","display_name":"Mohammad Shamsul Ola","orcid":"https://orcid.org/0000-0002-7479-8970","observed_orcids":["https://orcid.org/0000-0002-7479-8970"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mohammad Shamsul Ola","raw_affiliation_strings":["Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0002-7479-8970","affiliations":[{"raw_affiliation_string":"Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019571867","display_name":"Ahmad Ali","orcid":"https://orcid.org/0000-0003-4467-5387","observed_orcids":["https://orcid.org/0000-0003-4467-5387"]},"institutions":[{"id":"https://openalex.org/I169877490","display_name":"University of Mumbai","ror":"https://ror.org/032hdk172","country_code":"IN","type":"education","lineage":["https://openalex.org/I169877490"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ahmad Ali","raw_affiliation_strings":["Department of Life Sciences, University of Mumbai, Vidyanagari, Mumbai 400098, India"],"raw_orcid":"https://orcid.org/0000-0003-4467-5387","affiliations":[{"raw_affiliation_string":"Department of Life Sciences, University of Mumbai, Vidyanagari, Mumbai 400098, India","institution_ids":["https://openalex.org/I169877490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100685752","display_name":"Jie Zhang","orcid":"https://orcid.org/0000-0002-9745-664X","observed_orcids":["https://orcid.org/0000-0002-9745-664X","https://orcid.org/0009-0008-8664-0290"]},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jie Zhang","raw_affiliation_strings":["School of Engineering, Merz Court, Newcastle University, Newcastle upon Tyne NE1 7RU, UK"],"raw_orcid":"https://orcid.org/0000-0002-9745-664X","affiliations":[{"raw_affiliation_string":"School of Engineering, Merz Court, Newcastle University, Newcastle upon Tyne NE1 7RU, UK","institution_ids":["https://openalex.org/I84884186"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044752255","display_name":"Abdeltif Amrane","orcid":"https://orcid.org/0000-0003-2622-2384","observed_orcids":["https://orcid.org/0000-0003-2622-2384"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210090783","display_name":"Institut des Sciences Chimiques de Rennes","ror":"https://ror.org/00adwkx90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I28221208","https://openalex.org/I4210090783","https://openalex.org/I4210115835","https://openalex.org/I4210128300","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Abdeltif Amrane","raw_affiliation_strings":["National Higher School of Chemistry of Rennes, Scientific Research National Center (CNRS), Rennes Institute of Chemical Sciences\u2014Mixed Research Unit (ISCR\u2014UMR6226), Rennes University, 35000 Rennes, France"],"raw_orcid":"https://orcid.org/0000-0003-2622-2384","affiliations":[{"raw_affiliation_string":"National Higher School of Chemistry of Rennes, Scientific Research National Center (CNRS), Rennes Institute of Chemical Sciences\u2014Mixed Research Unit (ISCR\u2014UMR6226), Rennes University, 35000 Rennes, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210090783","https://openalex.org/I56067802"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5060574366"],"corresponding_institution_ids":["https://openalex.org/I4210130929"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3296},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3296},"fwci":1.0089,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.66187415,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"25","issue":"16","first_page":"9120","last_page":"9120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12748","display_name":"Molecular spectroscopy and chirality","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enantiomeric-separation","display_name":"enantiomer separation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/aromatic-amino-acids","display_name":"aromatic amino acids","score":0.9900000095367432},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.8840000033378601},{"id":"https://openalex.org/keywords/chiral-mobile-phase-additive","display_name":"chiral mobile phase additive","score":0.7210000157356262},{"id":"https://openalex.org/keywords/tryptophan-enantiomers","display_name":"tryptophan enantiomers","score":0.8690000176429749},{"id":"https://openalex.org/keywords/phenylalanine","display_name":"phenylalanine","score":0.9629999995231628},{"id":"https://openalex.org/keywords/phenylglycine","display_name":"phenylglycine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/chiral-recognition-mechanism","display_name":"chiral recognition mechanism","score":0.7609999775886536},{"id":"https://openalex.org/keywords/binding-affinity","display_name":"binding affinity","score":0.5950000286102295}],"concepts":[{"id":"https://openalex.org/C486523","wikidata":"https://www.wikidata.org/wiki/Q494483","display_name":"Enantiomer","level":2,"score":0.8437476754188538},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.6974759101867676},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6955850720405579},{"id":"https://openalex.org/C2780152424","wikidata":"https://www.wikidata.org/wiki/Q4826062","display_name":"AutoDock","level":4,"score":0.6483993530273438},{"id":"https://openalex.org/C156217769","wikidata":"https://www.wikidata.org/wiki/Q1050046","display_name":"Chiral resolution","level":3,"score":0.5801724791526794},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5247619152069092},{"id":"https://openalex.org/C73826308","wikidata":"https://www.wikidata.org/wiki/Q684907","display_name":"Elution","level":2,"score":0.496437132358551},{"id":"https://openalex.org/C47849319","wikidata":"https://www.wikidata.org/wiki/Q5101829","display_name":"Chiral derivatizing agent","level":4,"score":0.48671630024909973},{"id":"https://openalex.org/C16838498","wikidata":"https://www.wikidata.org/wiki/Q5101828","display_name":"Chiral column chromatography","level":3,"score":0.3950035870075226},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35538285970687866},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3502989709377289},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08380728960037231},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006020","descriptor_name":"Glycopeptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014640","descriptor_name":"Vancomycin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D024322","descriptor_name":"Amino Acids, Aromatic","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.3390/ijms25169120","doi":"https://doi.org/10.3390/ijms25169120","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25169120","pdf_url":"https://www.mdpi.com/1422-0067/25/16/9120/pdf?version=1724327398","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11354492","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11354492","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11354492/pdf/ijms-25-09120.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:39201804","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39201804","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04693024v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04693024","pdf_url":"https://hal.science/hal-04693024/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, 2024, 25 (16), pp.9120. ⟨10.3390/ijms25169120⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.25405/ncl.34505451","doi":"https://doi.org/10.25405/ncl.34505451","is_oa":true,"landing_page_url":"https://doi.org/10.25405/ncl.34505451","pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.25405/ncl.34505451.v1","doi":"https://doi.org/10.25405/ncl.34505451.v1","is_oa":true,"landing_page_url":"https://doi.org/10.25405/ncl.34505451.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306402485","display_name":"Newcastle University ePrints (Newcastle Univesity)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I84884186","host_organization_name":"Newcastle University","host_organization_lineage":["https://openalex.org/I84884186"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.3390/ijms25169120","doi":"https://doi.org/10.3390/ijms25169120","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25169120","pdf_url":"https://www.mdpi.com/1422-0067/25/16/9120/pdf?version=1724327398","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321145","display_name":"King Saud University","ror":"https://ror.org/02f81g417"},{"id":"https://openalex.org/F4320335007","display_name":"Direction G\u00e9n\u00e9rale de la Recherche Scientifique et du D\u00e9veloppement Technologique","ror":"https://ror.org/04jpfrv51"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401894698.pdf","grobid_xml":"https://content.openalex.org/works/W4401894698.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1205728809","https://openalex.org/W1968982597","https://openalex.org/W1982453052","https://openalex.org/W2001816314","https://openalex.org/W2023011118","https://openalex.org/W2026199113","https://openalex.org/W2027346893","https://openalex.org/W2066609771","https://openalex.org/W2084983500","https://openalex.org/W2088282077","https://openalex.org/W2091274993","https://openalex.org/W2094532595","https://openalex.org/W2134967712","https://openalex.org/W2149523040","https://openalex.org/W2484548469","https://openalex.org/W2608736098","https://openalex.org/W2783662659","https://openalex.org/W2810409743","https://openalex.org/W2884323962","https://openalex.org/W2913500214","https://openalex.org/W2943893168","https://openalex.org/W3000220411","https://openalex.org/W3049363456","https://openalex.org/W3102318441","https://openalex.org/W3113307769","https://openalex.org/W3186957570","https://openalex.org/W3195752047","https://openalex.org/W4200256651","https://openalex.org/W4206509885","https://openalex.org/W4212777366","https://openalex.org/W4281739141","https://openalex.org/W4283515345","https://openalex.org/W4303943922","https://openalex.org/W4317725491","https://openalex.org/W4327685821","https://openalex.org/W4362453719","https://openalex.org/W4377041849","https://openalex.org/W4381487432","https://openalex.org/W4384822311","https://openalex.org/W4386523944","https://openalex.org/W4387563099","https://openalex.org/W4389310530","https://openalex.org/W4390049991","https://openalex.org/W4390914878","https://openalex.org/W4399041980","https://openalex.org/W6715279657"],"related_works":["https://openalex.org/W7221184851","https://openalex.org/W2004037554","https://openalex.org/W2884425999","https://openalex.org/W7029054508","https://openalex.org/W2066528704","https://openalex.org/W2067875468","https://openalex.org/W1977486441","https://openalex.org/W2007790326","https://openalex.org/W2152104256","https://openalex.org/W2025878190"],"abstract_inverted_index":{"An":[0],"asymmetric":[1],"synthesis":[2],"is":[3],"a":[4,52,110,122,130,135],"favorable":[5],"approach":[6,199],"for":[7,141,159,213],"obtaining":[8],"enantiomerically":[9],"pure":[10],"substances,":[11],"but":[12],"racemic":[13],"resolution":[14,26,98,123,131,138],"remains":[15],"an":[16,65],"efficient":[17],"strategy.":[18],"This":[19,197],"study":[20],"aims":[21],"to":[22,80,92,150,173],"elucidate":[23,101,151],"the":[24,56,70,116,152,166,184,194,201],"chiral":[25,38,53,102,137,188,205,217],"of":[27,112,118,124,132,154],"aromatic":[28],"amino":[29,67],"acids":[30],"and":[31,89,100,126,143,156,161,193,207,215],"their":[32],"elution":[33,157],"order":[34,158],"using":[35,49],"glycopeptides":[36],"as":[37,51,69,107],"selectors":[39],"through":[40],"molecular":[41,82,208],"docking":[42,83,146,169],"analysis.":[43],"Chiral":[44],"separation":[45,117,155,218],"experiments":[46],"were":[47,171],"conducted":[48],"Vancomycin":[50,90,106],"additive":[54],"in":[55,175,190],"mobile":[57],"phase":[58],"(CMPA)":[59],"at":[60,109],"various":[61],"concentrations,":[62],"coupled":[63],"with":[64,121,129,178],"achiral":[66],"column":[68],"stationary":[71],"phase.":[72],"The":[73],"Autodock":[74],"Vina":[75],"1.1.2":[76],"software":[77],"was":[78,139,148],"employed":[79,149],"perform":[81],"simulations":[84],"between":[85,204],"each":[86],"enantiomer":[87],"(ligand)":[88],"(receptor)":[91],"evaluate":[93],"binding":[94,167],"affinities,":[95],"demonstrate":[96],"enantiomeric":[97],"feasibility,":[99],"recognition":[103,189],"mechanisms.":[104],"Utilizing":[105],"CMPA":[108],"concentration":[111],"1.5":[113],"mM":[114],"enabled":[115],"tryptophan":[119,160],"enantiomers":[120,128],"3.98":[125],"tyrosine":[127,162],"2.97.":[133],"However,":[134],"poor":[136],"observed":[140],"phenylalanine":[142],"phenylglycine.":[144],"Molecular":[145],"analysis":[147],"lack":[153],"enantiomers.":[163],"By":[164],"calculating":[165],"energy,":[168],"results":[170],"found":[172],"be":[174],"good":[176],"agreement":[177],"experimental":[179],"findings,":[180],"providing":[181],"insights":[182],"into":[183],"underlying":[185],"mechanisms":[186],"governing":[187],"this":[191],"system":[192],"interaction":[195],"sites.":[196],"comprehensive":[198],"clarifies":[200],"complex":[202],"relationship":[203],"discrimination":[206],"architecture,":[209],"offering":[210],"valuable":[211],"information":[212],"creating":[214],"improving":[216],"protocols.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-08-27T00:00:00"}