{"id":"https://openalex.org/W4401856476","doi":"https://doi.org/10.3390/jcm13164902","title":"Pallidal Versus Subthalamic Deep-Brain Stimulation for Generalized Isolated Dystonia: A Retrospective Study","display_name":"Pallidal Versus Subthalamic Deep-Brain Stimulation for Generalized Isolated Dystonia: A Retrospective Study","publication_year":2024,"publication_date":"2024-08-20","ids":{"openalex":"https://openalex.org/W4401856476","doi":"https://doi.org/10.3390/jcm13164902","pmid":"https://pubmed.ncbi.nlm.nih.gov/39201044"},"language":"en","primary_location":{"id":"doi:10.3390/jcm13164902","doi":"https://doi.org/10.3390/jcm13164902","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164902","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4902/pdf?version=1724134751","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/13/16/4902/pdf?version=1724134751","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101811478","display_name":"Jingchao Wu","orcid":"https://orcid.org/0000-0003-0569-2328","observed_orcids":["https://orcid.org/0000-0003-0569-2328"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]},{"id":"https://openalex.org/I4210102371","display_name":"Tianjin Huanhu Hospital","ror":"https://ror.org/00q6wbs64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210102371"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingchao Wu","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin 300000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]},{"raw_affiliation_string":"Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin 300000, China","institution_ids":["https://openalex.org/I4210102371"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042800587","display_name":"Guanyu Zhu","orcid":"https://orcid.org/0000-0002-8679-7473","observed_orcids":["https://orcid.org/0000-0002-8679-7473"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanyu Zhu","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022944399","display_name":"Yifei Gan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifei Gan","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101805929","display_name":"Fangang Meng","orcid":"https://orcid.org/0000-0002-8577-6443","observed_orcids":["https://orcid.org/0000-0002-8577-6443"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fangang Meng","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051255797","display_name":"Anchao Yang","orcid":"https://orcid.org/0000-0001-9179-5571","observed_orcids":["https://orcid.org/0000-0001-9179-5571"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anchao Yang","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100461787","display_name":"Jianguo Zhang","orcid":"https://orcid.org/0000-0002-0009-0574","observed_orcids":["https://orcid.org/0000-0002-0009-0574"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210087691","display_name":"Beijing Tian Tan Hospital","ror":"https://ror.org/003regz62","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210087691"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianguo Zhang","raw_affiliation_strings":["Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China"],"raw_orcid":"https://orcid.org/0000-0002-0009-0574","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100461787"],"corresponding_institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210087691"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2955},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2955},"fwci":0.6999,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.69897777,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"13","issue":"16","first_page":"4902","last_page":"4902"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11123","display_name":"Obsessive-Compulsive Spectrum Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11274","display_name":"Botulinum Toxin and Related Neurological Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"deep brain stimulation","score":0.9100000262260437},{"id":"https://openalex.org/keywords/subthalamic-nucleus","display_name":"subthalamic nucleus","score":0.9139999747276306},{"id":"https://openalex.org/keywords/globus-pallidus-internus","display_name":"globus pallidus internus","score":0.9350000023841858},{"id":"https://openalex.org/keywords/burke-fahn-marsden-dystonia-rating-scale","display_name":"Burke-Fahn-Marsden Dystonia Rating Scale","score":0.8859999775886536},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9340000152587891},{"id":"https://openalex.org/keywords/functional-outcome","display_name":"functional outcome","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.962321400642395},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.9245232343673706},{"id":"https://openalex.org/C2778559928","wikidata":"https://www.wikidata.org/wiki/Q906492","display_name":"Dystonia","level":2,"score":0.7992027997970581},{"id":"https://openalex.org/C2777319143","wikidata":"https://www.wikidata.org/wiki/Q2270424","display_name":"Subthalamic nucleus","level":5,"score":0.6789777278900146},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5270312428474426},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.42742565274238586},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3737233877182007},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.35235869884490967},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33962738513946533},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20025280117988586},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.19783371686935425},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.16544044017791748},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.06837838888168335},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/jcm13164902","doi":"https://doi.org/10.3390/jcm13164902","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164902","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4902/pdf?version=1724134751","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmid:39201044","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39201044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11355894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11355894","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11355894/pdf/jcm-13-04902.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Clin Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/jcm13164902","doi":"https://doi.org/10.3390/jcm13164902","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164902","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4902/pdf?version=1724134751","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2740011327","display_name":null,"funder_award_id":"82201634","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2796231011","display_name":null,"funder_award_id":"21JCYBJC01440","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401856476.pdf","grobid_xml":"https://content.openalex.org/works/W4401856476.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1575398403","https://openalex.org/W2008123743","https://openalex.org/W2015213210","https://openalex.org/W2037377025","https://openalex.org/W2039589042","https://openalex.org/W2050540607","https://openalex.org/W2055760087","https://openalex.org/W2074509248","https://openalex.org/W2075021671","https://openalex.org/W2091046222","https://openalex.org/W2110255132","https://openalex.org/W2131134103","https://openalex.org/W2132704449","https://openalex.org/W2159518696","https://openalex.org/W2258466720","https://openalex.org/W2417300586","https://openalex.org/W2807310819","https://openalex.org/W2901841139","https://openalex.org/W2939884160","https://openalex.org/W4213070787","https://openalex.org/W4223521132","https://openalex.org/W4280631735","https://openalex.org/W4292806894","https://openalex.org/W4292877285"],"related_works":["https://openalex.org/W2518873333","https://openalex.org/W2093780015","https://openalex.org/W3030846630","https://openalex.org/W3136337443","https://openalex.org/W4289755640","https://openalex.org/W3029352154","https://openalex.org/W4244840723","https://openalex.org/W4301179225","https://openalex.org/W2607326016","https://openalex.org/W4310267060"],"abstract_inverted_index":{"Objectives:":[0],"Deep-brain":[1],"stimulation":[2,180],"(DBS)":[3],"has":[4],"been":[5],"used":[6,95,113],"for":[7,31],"the":[8,24,55,61,66,88,98,116,127,135,142,148,153,159,171,182],"treatment":[9,52],"of":[10,27,68,87,100,107,120,170,181,196],"medically":[11],"refractory":[12],"dystonia":[13,47,90],"with":[14,44,217],"excellent":[15],"results.":[16],"In":[17,36],"this":[18,37],"study,":[19,39],"we":[20,40],"compared":[21],"in":[22,65,126,141,147,162,204,215],"detail":[23],"therapeutic":[25],"advantages":[26,212],"two":[28],"DBS":[29,51,169],"targets":[30],"generalized":[32,45],"isolated":[33,46],"dystonia.":[34,220],"Methods:":[35],"retrospective":[38],"recruited":[41],"29":[42],"patients":[43,216],"who":[48],"had":[49,198,222],"undergone":[50],"targeting":[53],"either":[54],"globus":[56],"pallidus":[57],"interna":[58],"(GPi)":[59],"or":[60],"subthalamic":[62],"nucleus":[63],"(STN)":[64],"Department":[67],"Functional":[69],"Neurosurgery":[70],"at":[71,130],"Tiantan":[72],"Hospital,":[73],"Beijing,":[74],"China,":[75],"between":[76],"January":[77],"2016":[78],"and":[79,84,104,156,175,186],"December":[80],"2021.":[81],"The":[82,123],"movement":[83],"disability":[85],"subscales":[86,203],"Burke\u2013Fahn\u2013Marsden":[89],"rating":[91],"scale":[92],"(BFMDRS)":[93],"were":[94],"to":[96,114,134],"assess":[97],"severity":[99],"their":[101,105],"dystonic":[102],"symptoms":[103,164],"activities":[106],"daily":[108],"living,":[109],"respectively.":[110],"SF-36":[111,202],"was":[112,138,165],"evaluate":[115],"patients\u2019":[117],"health-related":[118],"quality":[119,195],"life.":[121],"Results:":[122],"percentage":[124,160],"improvement":[125,161],"BFMDRS-M":[128],"score":[129,137],"6":[131,230],"months":[132,191,231],"relative":[133],"baseline":[136],"clearly":[139],"higher":[140,167],"STN":[143,172],"group":[144,150],"(63.91%)":[145],"than":[146,178,213,227],"GPi":[149,183],"(38.36%).":[151],"At":[152,189],"3-,":[154],"6-,":[155],"12-month":[157],"follow-ups,":[158],"arm":[163,219],"significantly":[166],"after":[168,179,192,232],"(70.64%,":[173],"80.66%,":[174],"76.89%,":[176],"respectively)":[177],"(36.75%,":[184],"34.21%,":[185],"38.47%,":[187],"respectively).":[188],"12":[190],"surgery,":[193],"patient":[194],"life":[197],"improved":[199],"on":[200],"all":[201],"both":[205],"groups.":[206],"Conclusions:":[207],"STN-DBS":[208,221],"may":[209],"have":[210],"more":[211],"GPi-DBS":[214,228],"obvious":[218],"a":[223],"better":[224],"clinical":[225],"effect":[226],"within":[229],"surgery.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-10T00:00:00"}