{"id":"https://openalex.org/W4401809246","doi":"https://doi.org/10.1109/atsip62566.2024.10638993","title":"Enhancing Medication Safety with Large Language Models: Advanced Detection and Prediction of Drug-Drug Interactions","display_name":"Enhancing Medication Safety with Large Language Models: Advanced Detection and Prediction of Drug-Drug Interactions","publication_year":2024,"publication_date":"2024-07-11","ids":{"openalex":"https://openalex.org/W4401809246","doi":"https://doi.org/10.1109/atsip62566.2024.10638993"},"language":"en","primary_location":{"id":"doi:10.1109/atsip62566.2024.10638993","doi":"https://doi.org/10.1109/atsip62566.2024.10638993","is_oa":false,"landing_page_url":"https://doi.org/10.1109/atsip62566.2024.10638993","pdf_url":null,"source":{"id":"https://openalex.org/S4306423244","display_name":"International Conference on Advanced Technologies for Signal and Image Processing","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE 7th International Conference on Advanced Technologies, Signal and Image Processing (ATSIP)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5106677010","display_name":"Basma Mohammed J. Alshehri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Basma Mohammed J. Alshehri","raw_affiliation_strings":["King Khalid University,College of Computer Science,Abha,Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Khalid University,College of Computer Science,Abha,Saudi Arabia","institution_ids":["https://openalex.org/I82952536"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062918876","display_name":"Naoufel Kra\u00efem","orcid":"https://orcid.org/0000-0003-1798-2883","observed_orcids":["https://orcid.org/0000-0003-1798-2883"]},"institutions":[{"id":"https://openalex.org/I4405260920","display_name":"National School of Computer Science","ror":"https://ror.org/04g1met76","country_code":"TN","type":"education","lineage":["https://openalex.org/I4405260920"]},{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]},{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["SA","TN"],"is_corresponding":false,"raw_author_name":"Naoufel Kraiem","raw_affiliation_strings":["King Khalid University RIADI Laboratory, ENSI; Manouba University, Tunisia,College of Computer Science,Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Khalid University RIADI Laboratory, ENSI; Manouba University, Tunisia,College of Computer Science,Saudi Arabia","institution_ids":["https://openalex.org/I4405260920","https://openalex.org/I82952536","https://openalex.org/I83259278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020556015","display_name":"Houneida Sakly","orcid":"https://orcid.org/0000-0001-8018-5129","observed_orcids":["https://orcid.org/0000-0001-8018-5129"]},"institutions":[{"id":"https://openalex.org/I4405260920","display_name":"National School of Computer Science","ror":"https://ror.org/04g1met76","country_code":"TN","type":"education","lineage":["https://openalex.org/I4405260920"]},{"id":"https://openalex.org/I83259278","display_name":"Manouba University","ror":"https://ror.org/0503ejf32","country_code":"TN","type":"education","lineage":["https://openalex.org/I83259278"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Houneida Sakly","raw_affiliation_strings":["Manouba University,Center for Research on Microelectronics and Nanotechnology (CRMN) RIADI Laboratory, ENSI,Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manouba University,Center for Research on Microelectronics and Nanotechnology (CRMN) RIADI Laboratory, ENSI,Tunisia","institution_ids":["https://openalex.org/I4405260920","https://openalex.org/I83259278"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015556666","display_name":"Nada Abdulaziz Alasbali","orcid":"https://orcid.org/0000-0003-2541-7876","observed_orcids":["https://orcid.org/0000-0003-2541-7876"]},"institutions":[{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Nada Alasbali","raw_affiliation_strings":["King Khalid University,College of Computer Science,Abha,Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King Khalid University,College of Computer Science,Abha,Saudi Arabia","institution_ids":["https://openalex.org/I82952536"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.9364,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.97237077,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"547","last_page":"552"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.5615000128746033,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.20499999821186066,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.10679999738931656,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.9869999885559082},{"id":"https://openalex.org/keywords/large-language-models","display_name":"large language models","score":0.828000009059906},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.8140000104904175},{"id":"https://openalex.org/keywords/polypharmacy","display_name":"polypharmacy","score":0.972000002861023},{"id":"https://openalex.org/keywords/natural-language-processing","display_name":"natural language processing","score":0.6259999871253967},{"id":"https://openalex.org/keywords/patient-safety","display_name":"patient safety","score":0.6129999756813049},{"id":"https://openalex.org/keywords/treatment-regimen-optimization","display_name":"treatment regimen optimization","score":0.7160000205039978},{"id":"https://openalex.org/keywords/clinical-decision-support","display_name":"clinical decision support","score":0.8529999852180481}],"concepts":[{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.797579288482666},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6198464035987854},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.4046565592288971},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.21915432810783386},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21422970294952393}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/atsip62566.2024.10638993","doi":"https://doi.org/10.1109/atsip62566.2024.10638993","is_oa":false,"landing_page_url":"https://doi.org/10.1109/atsip62566.2024.10638993","pdf_url":null,"source":{"id":"https://openalex.org/S4306423244","display_name":"International Conference on Advanced Technologies for Signal and Image Processing","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE 7th International Conference on Advanced Technologies, Signal and Image Processing (ATSIP)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9789000153541565,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1926073906","https://openalex.org/W4280639694","https://openalex.org/W4310014465","https://openalex.org/W4318150241"],"related_works":["https://openalex.org/W7163627746","https://openalex.org/W7217215626","https://openalex.org/W6893339732","https://openalex.org/W7221965164","https://openalex.org/W7154382446","https://openalex.org/W7216347470","https://openalex.org/W7161251217","https://openalex.org/W4416971715","https://openalex.org/W4413440773","https://openalex.org/W6912154974"],"abstract_inverted_index":{"Poly-pharmacy":[0],"means":[1],"the":[2,13,16,45,54,63,102,110,126],"use":[3,62],"of":[4,15,18,47,56,129],"multiple":[5,8],"medications":[6],"for":[7,112],"Diseases,":[9],"with":[10],"impact":[11],"to":[12,28,40,52,61,92,96,118],"increases":[14],"risk":[17],"drug-drug":[19],"interactions":[20],"(DDIs),":[21],"and":[22,38,60,86,100,115,139,144],"it":[23],"may":[24],"cause":[25],"a":[26,76],"threat":[27],"patient":[29,81,142],"safety.":[30],"Traditional":[31],"DDI":[32,58],"detection":[33],"methods":[34],"are":[35],"often":[36],"manual":[37],"leads":[39],"errors.":[41],"This":[42],"study":[43],"investigates":[44],"potential":[46,128],"large":[48],"language":[49,70],"models":[50],"(LLMs)":[51],"improve":[53,101,119],"efficiency":[55],"personalized":[57],"prediction":[59,120],"AI":[64],"advancements.":[65],"By":[66],"using":[67],"LLMs\u2019":[68],"natural":[69],"processing":[71],"capabilities,":[72],"we":[73],"will":[74],"develop":[75],"system":[77,90],"that":[78],"analyzes":[79],"comprehensive":[80],"data,":[82],"including":[83],"medical":[84],"history,":[85],"individual":[87],"characteristics.":[88],"The":[89],"aims":[91],"enabling":[93],"healthcare":[94],"providers":[95],"make":[97],"informed":[98],"decisions":[99],"treatment":[103,137,145],"plans.":[104],"Initial":[105],"results,":[106],"while":[107],"promising,":[108],"highlight":[109],"need":[111],"further":[113],"refinement":[114],"larger":[116],"datasets":[117],"accuracy.":[121],"However,":[122],"this":[123],"research":[124],"demonstrates":[125],"significant":[127],"LLM-based":[130],"systems":[131],"in":[132],"transforming":[133],"medication":[134],"safety,":[135],"optimizing":[136],"regimens,":[138],"ultimately":[140],"enhancing":[141],"care":[143],"process.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-08-24T00:00:00"}