{"id":"https://openalex.org/W4401749556","doi":"https://doi.org/10.1109/isbi56570.2024.10635570","title":"Automated Measurement of Pericoronary Adipose Tissue Attenuation and Volume in Ct Angiography","display_name":"Automated Measurement of Pericoronary Adipose Tissue Attenuation and Volume in Ct Angiography","publication_year":2024,"publication_date":"2024-05-27","ids":{"openalex":"https://openalex.org/W4401749556","doi":"https://doi.org/10.1109/isbi56570.2024.10635570"},"language":"en","primary_location":{"id":"doi:10.1109/isbi56570.2024.10635570","doi":"https://doi.org/10.1109/isbi56570.2024.10635570","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635570","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["arxiv","crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2311.13100","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089433097","display_name":"Andrew Nguyen","orcid":"https://orcid.org/0000-0003-1416-0729","observed_orcids":["https://orcid.org/0000-0003-1416-0729"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew M. Nguyen","raw_affiliation_strings":["Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048201234","display_name":"Tejas Sudharshan Mathai","orcid":"https://orcid.org/0009-0005-8440-1702","observed_orcids":["https://orcid.org/0009-0005-8440-1702"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tejas Sudharshan Mathai","raw_affiliation_strings":["Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018607348","display_name":"Liangchen Liu","orcid":"https://orcid.org/0000-0002-6539-5408","observed_orcids":["https://orcid.org/0000-0002-6539-5408"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liangchen Liu","raw_affiliation_strings":["Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101543446","display_name":"Jianfei Liu","orcid":"https://orcid.org/0000-0003-2145-7205","observed_orcids":["https://orcid.org/0000-0003-2145-7205"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianfei Liu","raw_affiliation_strings":["Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016047550","display_name":"Ronald M. Summers","orcid":"https://orcid.org/0000-0001-8081-7376","observed_orcids":["https://orcid.org/0000-0001-8081-7376"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald M. Summers","raw_affiliation_strings":["Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Sciences, National Institutes of Health Clinical Center,Imaging Biomarkers and Computer-Aided Diagnosis Laboratory,Bethesda,MD,USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4413,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.77847911,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.7904999852180481,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.1459999978542328,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.041099999099969864,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pericoronary-adipose-tissue","display_name":"pericoronary adipose tissue","score":1.0},{"id":"https://openalex.org/keywords/coronary-ct-angiography","display_name":"coronary CT angiography","score":0.8949999809265137},{"id":"https://openalex.org/keywords/coronary-inflammation","display_name":"coronary inflammation","score":0.6000000238418579},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.8999999761581421},{"id":"https://openalex.org/keywords/coronary-artery-segmentation","display_name":"coronary artery segmentation","score":0.625},{"id":"https://openalex.org/keywords/left-coronary-artery","display_name":"left coronary artery","score":0.7269999980926514},{"id":"https://openalex.org/keywords/right-coronary-artery","display_name":"right coronary artery","score":1.0},{"id":"https://openalex.org/keywords/adipose-tissue-volume","display_name":"adipose tissue volume","score":0.9639999866485596},{"id":"https://openalex.org/keywords/nnu-net","display_name":"nnU-Net","score":0.8080000281333923},{"id":"https://openalex.org/keywords/automated-image-analysis","display_name":"automated image analysis","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C184652730","wikidata":"https://www.wikidata.org/wiki/Q2357982","display_name":"Attenuation","level":2,"score":0.7175943851470947},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.6389222145080566},{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.6157877445220947},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.4952785074710846},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3829217553138733},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3788670301437378},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32156115770339966},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2567470073699951},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15856635570526123},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12918972969055176},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.11839085817337036},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi56570.2024.10635570","doi":"https://doi.org/10.1109/isbi56570.2024.10635570","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi56570.2024.10635570","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:arXiv.org:2311.13100","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2311.13100","pdf_url":"https://arxiv.org/pdf/2311.13100","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2311.13100","doi":"https://doi.org/10.48550/arxiv.2311.13100","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2311.13100","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2311.13100","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2311.13100","pdf_url":"https://arxiv.org/pdf/2311.13100","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4206843316","display_name":"Computer Aided Detection for Radiologic Images","funder_award_id":"Z01CL040004","funder_id":"https://openalex.org/F4320337376","funder_display_name":"NIH Clinical Center"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401749556.pdf","grobid_xml":"https://content.openalex.org/works/W4401749556.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W2101234009","https://openalex.org/W2883495901","https://openalex.org/W2888909234","https://openalex.org/W2915032895","https://openalex.org/W2917025828","https://openalex.org/W2963753252","https://openalex.org/W3004870713","https://openalex.org/W3014974815","https://openalex.org/W3017406301","https://openalex.org/W3045560880","https://openalex.org/W3095173492","https://openalex.org/W3149060137","https://openalex.org/W4282923764","https://openalex.org/W4294125996","https://openalex.org/W4313644769","https://openalex.org/W4383218413","https://openalex.org/W4385813883","https://openalex.org/W6785104013"],"related_works":["https://openalex.org/W7154248031","https://openalex.org/W7130681751","https://openalex.org/W4313644769","https://openalex.org/W3144930148","https://openalex.org/W6889684182","https://openalex.org/W7214187120","https://openalex.org/W4407020140","https://openalex.org/W3164138037","https://openalex.org/W3094172308","https://openalex.org/W3158127321"],"abstract_inverted_index":{"Pericoronary":[0],"adipose":[1],"tissue":[2],"(PCAT)":[3],"is":[4,17,34],"the":[5,10,13,41,61,67,83,92,107,132,151,171,191,194,201,217],"deposition":[6],"of":[7,12,20,40,46,85,104,145,158,163,178,183,196,235],"fat":[8,47],"in":[9,91,131],"vicinity":[11],"coronary":[14,21,26,30,63,69,96],"arteries.":[15,97],"It":[16],"an":[18],"indicator":[19],"inflammation":[22,236],"and":[23,44,89,124,160,180,213,219,237],"associated":[24],"with":[25],"artery":[27,64,70],"disease.":[28,239],"Non-invasive":[29],"CT":[31],"angiography":[32],"(CCTA)":[33],"presently":[35],"used":[36,100],"to":[37,114,121,203,209],"obtain":[38],"measures":[39],"thickness,":[42],"volume,":[43],"attenuation":[45,88,162,182,212],"deposition.":[48],"However,":[49],"prior":[50],"works":[51],"solely":[52],"focus":[53],"on":[54,140],"measuring":[55],"PCAT":[56,86,130,161,181,211,226],"using":[57],"semi-automated":[58],"approaches":[59],"at":[60,215],"right":[62],"(RCA)":[65],"over":[66],"left":[68],"(LCA).":[71],"In":[72],"this":[73],"pilot":[74],"work,":[75],"we":[76,99,127,199],"developed":[77],"a":[78,101,116,141,174,205,231],"fully":[79,206],"automated":[80,207,225],"approach":[81],"for":[82,170,190,233],"measurement":[84,227],"mean":[87,155,175],"volume":[90,214],"region":[93],"around":[94],"both":[95,216],"First,":[98],"large":[102],"subset":[103],"patients":[105,146],"from":[106,150],"public":[108],"Im-ageCAS":[109],"dataset":[110],"(n":[111,147],"=":[112,148],"735)":[113],"train":[115],"3D":[117],"full":[118],"resolution":[119],"nnUNet":[120],"segment":[122],"LCA":[123],"RCA.":[125],"Then,":[126],"automatically":[128],"measured":[129],"surrounding":[133],"arterial":[134],"regions.":[135],"We":[136],"evaluated":[137],"our":[138,197],"method":[139,208],"held-out":[142],"test":[143],"set":[144],"183)":[149],"same":[152],"dataset.":[153],"A":[154],"Dice":[156,176],"score":[157,177],"83%":[159],"-73.81":[164],"\u00b1":[165,185],"12.69":[166],"HU":[167,187],"was":[168,188],"calculated":[169],"RCA,":[172],"while":[173],"81%":[179],"-77.51":[184],"7.94":[186],"computed":[189],"LCA.":[192,220],"To":[193],"best":[195],"knowledge,":[198],"are":[200],"first":[202],"develop":[204],"measure":[210],"RCA":[218],"Our":[221],"work":[222],"underscores":[223],"how":[224],"holds":[228],"promise":[229],"as":[230],"biomarker":[232],"identification":[234],"cardiac":[238]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-08-23T00:00:00"}