{"id":"https://openalex.org/W4401728946","doi":"https://doi.org/10.1038/s41467-024-51409-3","title":"Nickel(II)/BINOL-catalyzed enantioselective C\u2013H activation via desymmetrization and kinetic resolution","display_name":"Nickel(II)/BINOL-catalyzed enantioselective C\u2013H activation via desymmetrization and kinetic resolution","publication_year":2024,"publication_date":"2024-08-20","ids":{"openalex":"https://openalex.org/W4401728946","doi":"https://doi.org/10.1038/s41467-024-51409-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/39164290"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-024-51409-3","doi":"https://doi.org/10.1038/s41467-024-51409-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-51409-3","pdf_url":"https://www.nature.com/articles/s41467-024-51409-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-024-51409-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056567982","display_name":"Qi\u2010Jun Yao","orcid":"https://orcid.org/0000-0002-2872-7688","observed_orcids":["https://orcid.org/0000-0002-2872-7688"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi-Jun Yao","raw_affiliation_strings":["Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China"],"raw_orcid":"https://orcid.org/0000-0002-2872-7688","affiliations":[{"raw_affiliation_string":"Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024809370","display_name":"Fan\u2010Rui Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fan-Rui Huang","raw_affiliation_strings":["Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101957373","display_name":"Jiahao Chen","orcid":"https://orcid.org/0000-0002-4581-1152","observed_orcids":["https://orcid.org/0000-0002-4581-1152"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia-Hao Chen","raw_affiliation_strings":["Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058718448","display_name":"Bing\u2010Feng Shi","orcid":"https://orcid.org/0000-0003-0375-955X","observed_orcids":["https://orcid.org/0000-0003-0375-955X"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bing-Feng Shi","raw_affiliation_strings":["Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China. bfshi@zju.edu.cn","Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China"],"raw_orcid":"https://orcid.org/0000-0003-0375-955X","affiliations":[{"raw_affiliation_string":"Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China. bfshi@zju.edu.cn","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058718448"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":{"value":6790,"currency":"USD","value_usd":6790},"apc_paid":{"value":6790,"currency":"USD","value_usd":6790},"fwci":3.389,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.9414454,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"7135","last_page":"7135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.4584999978542328,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.4584999978542328,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis","score":0.24210000038146973,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.20520000159740448,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nickel-ii-catalysis","display_name":"nickel(II) catalysis","score":0.8619999885559082},{"id":"https://openalex.org/keywords/enantioselective-c-h-activation","display_name":"enantioselective C\u2013H activation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/binol-ligands","display_name":"BINOL ligands","score":0.7360000014305115},{"id":"https://openalex.org/keywords/desymmetrization","display_name":"desymmetrization","score":0.8600000143051147},{"id":"https://openalex.org/keywords/kinetic-resolution","display_name":"kinetic resolution","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nickelacycles","display_name":"nickelacycles","score":0.6660000085830688},{"id":"https://openalex.org/keywords/deuterium-labeling","display_name":"deuterium labeling","score":0.7459999918937683},{"id":"https://openalex.org/keywords/chiral-ligands","display_name":"chiral ligands","score":0.6370000243186951},{"id":"https://openalex.org/keywords/air-stable-catalysts","display_name":"air-stable catalysts","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.9429666996002197},{"id":"https://openalex.org/C2777190055","wikidata":"https://www.wikidata.org/wiki/Q3045251","display_name":"Desymmetrization","level":4,"score":0.9302383065223694},{"id":"https://openalex.org/C28173026","wikidata":"https://www.wikidata.org/wiki/Q337361","display_name":"Kinetic resolution","level":4,"score":0.8063463568687439},{"id":"https://openalex.org/C504270822","wikidata":"https://www.wikidata.org/wiki/Q744","display_name":"Nickel","level":2,"score":0.745611310005188},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.7322999238967896},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6258160471916199},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.6008168458938599},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.4615170657634735},{"id":"https://openalex.org/C2776910235","wikidata":"https://www.wikidata.org/wiki/Q18574","display_name":"Reactivity (psychology)","level":3,"score":0.4252763092517853},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3878073990345001},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.23336049914360046},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1038/s41467-024-51409-3","doi":"https://doi.org/10.1038/s41467-024-51409-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-51409-3","pdf_url":"https://www.nature.com/articles/s41467-024-51409-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmid:39164290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39164290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11336223","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11336223","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11336223/pdf/41467_2024_Article_51409.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-51409-3","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-024-51409-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:8abc66a18a8549d9bf2b9e29b403c31b","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/8abc66a18a8549d9bf2b9e29b403c31b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-024-51409-3","doi":"https://doi.org/10.1038/s41467-024-51409-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-51409-3","pdf_url":"https://www.nature.com/articles/s41467-024-51409-3.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1188701664","display_name":null,"funder_award_id":"92256302","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1904885188","display_name":null,"funder_award_id":"U22A20388","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2552757462","display_name":null,"funder_award_id":"21925109, U22A20388 and 92256302","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G32912696","display_name":null,"funder_award_id":"226\u20132024\u201300003","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G3735776375","display_name":null,"funder_award_id":"21925109","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5980382992","display_name":"\u94af\u50ac\u5316\u7532\u57fa\u78b3\u6c22\u952e\u4e0d\u5bf9\u79f0\u5b98\u80fd\u56e2\u5316\u5408\u6210\u5948\u8bfa\u6c99\u661f","funder_award_id":"LD22B030003","funder_id":"https://openalex.org/F4320338464","funder_display_name":"Natural Science Foundation of Zhejiang Province"},{"id":"https://openalex.org/G8858542747","display_name":null,"funder_award_id":"U22A20388 and 92256302","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G994836788","display_name":null,"funder_award_id":"226202200224","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322927","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401728946.pdf","grobid_xml":"https://content.openalex.org/works/W4401728946.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W1972577346","https://openalex.org/W1978851116","https://openalex.org/W1988085628","https://openalex.org/W1994390276","https://openalex.org/W2010617308","https://openalex.org/W2040203021","https://openalex.org/W2069467262","https://openalex.org/W2077657121","https://openalex.org/W2092137385","https://openalex.org/W2109932330","https://openalex.org/W2114424373","https://openalex.org/W2117049860","https://openalex.org/W2126982344","https://openalex.org/W2135346135","https://openalex.org/W2156241789","https://openalex.org/W2164565807","https://openalex.org/W2314934082","https://openalex.org/W2321571989","https://openalex.org/W2324322254","https://openalex.org/W2327227881","https://openalex.org/W2328190216","https://openalex.org/W2333335708","https://openalex.org/W2509460884","https://openalex.org/W2580645602","https://openalex.org/W2589065087","https://openalex.org/W2729962413","https://openalex.org/W2769850912","https://openalex.org/W2787869092","https://openalex.org/W2793022800","https://openalex.org/W2796901376","https://openalex.org/W2891239222","https://openalex.org/W2903181213","https://openalex.org/W2924916858","https://openalex.org/W2937194210","https://openalex.org/W2945957549","https://openalex.org/W2960433444","https://openalex.org/W2965344939","https://openalex.org/W2981241106","https://openalex.org/W3002672871","https://openalex.org/W3003192628","https://openalex.org/W3010023003","https://openalex.org/W3012159926","https://openalex.org/W3013842774","https://openalex.org/W3014364773","https://openalex.org/W3036599194","https://openalex.org/W3037718333","https://openalex.org/W3048340448","https://openalex.org/W3080777656","https://openalex.org/W3103948041","https://openalex.org/W3126612208","https://openalex.org/W3195250230","https://openalex.org/W4205886786","https://openalex.org/W4303432680","https://openalex.org/W4307385618","https://openalex.org/W4366163487","https://openalex.org/W4385444121","https://openalex.org/W4392137671"],"related_works":["https://openalex.org/W3158793999","https://openalex.org/W2112828623","https://openalex.org/W2783172341","https://openalex.org/W2067914620","https://openalex.org/W2088967451","https://openalex.org/W2342448947","https://openalex.org/W2073542213","https://openalex.org/W4254791068","https://openalex.org/W4254909358","https://openalex.org/W3004942978"],"abstract_inverted_index":{"The":[0],"field":[1],"of":[2,15,27,73,106,116,139,146,175],"nickel":[3,16,155],"catalysis":[4],"has":[5],"witnessed":[6],"remarkable":[7],"growth":[8],"in":[9,18,77],"recent":[10],"years.":[11],"However,":[12],"the":[13,71,107,112,125,129,137,168],"use":[14],"catalysts":[17],"enantioselective":[19,43,97,161,172],"C\u2013H":[20,44,98,122,163,173],"activation":[21,45,164,174],"remains":[22,165],"a":[23,63,178],"daunting":[24],"challenge":[25],"because":[26],"their":[28],"variable":[29],"oxidation":[30],"states,":[31],"intricate":[32],"coordination":[33],"chemistry,":[34],"and":[35,51,57,85,100,114,132],"unpredictable":[36],"reactivity":[37],"patterns.":[38],"Herein,":[39],"we":[40],"report":[41,170],"an":[42,171],"reaction":[46],"catalyzed":[47],"by":[48,154],"commercially":[49],"available":[50,56],"air-stable":[52],"nickel(II)":[53,118],"catalyst.":[54],"Readily":[55],"simple":[58,68],"(S)-BINOL":[59],"is":[60,124,158],"used":[61],"as":[62],"chiral":[64,75,90,117],"ligand.":[65],"This":[66],"operationally":[67],"protocol":[69],"enables":[70],"synthesis":[72,131],"planar":[74,89],"metallocenes":[76,176],"high":[78],"yields":[79],"with":[80],"excellent":[81],"enantioselectivity":[82],"through":[83],"desymmetrization":[84],"kinetic":[86],"resolution.":[87],"Air-stable":[88],"nickelacycle":[91],"intermediates":[92,105],"are":[93],"first":[94],"synthesized":[95],"via":[96,177],"nickelation":[99],"shown":[101],"to":[102,151],"be":[103,152],"possible":[104],"reaction.":[108],"Deuterium-labeling":[109],"studies,":[110],"alongside":[111],"characterization":[113],"transformation":[115],"species,":[119],"suggest":[120],"that":[121],"cleavage":[123],"enantio-determining":[126],"step.":[127],"Moreover,":[128],"large-scale":[130],"diverse":[133],"synthetic":[134],"transformations":[135],"underscore":[136],"practicality":[138],"this":[140],"protocol.":[141],"While":[142],"many":[143],"catalytic":[144,180],"modes":[145],"palladium":[147],"have":[148],"been":[149],"able":[150],"supplanted":[153],"catalysis,":[156],"which":[157],"more":[159],"Earth-abundant,":[160],"nickel-catalysed":[162],"unexplored.":[166],"Here,":[167],"authors":[169],"nickel\u20131\u2032-bi-2-naphthol":[179],"system.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":3}],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2025-10-10T00:00:00"}
