{"id":"https://openalex.org/W4401484392","doi":"https://doi.org/10.3390/jcm13164684","title":"Markers of Futile Resuscitation in Traumatic Hemorrhage: A Review of the Evidence and a Proposal for Futility Time-Outs during Massive Transfusion","display_name":"Markers of Futile Resuscitation in Traumatic Hemorrhage: A Review of the Evidence and a Proposal for Futility Time-Outs during Massive Transfusion","publication_year":2024,"publication_date":"2024-08-09","ids":{"openalex":"https://openalex.org/W4401484392","doi":"https://doi.org/10.3390/jcm13164684","pmid":"https://pubmed.ncbi.nlm.nih.gov/39200824","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11355875"},"language":"en","primary_location":{"id":"doi:10.3390/jcm13164684","doi":"https://doi.org/10.3390/jcm13164684","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164684","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4684/pdf?version=1723199631","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/13/16/4684/pdf?version=1723199631","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041923386","display_name":"Mark M. Walsh","orcid":"https://orcid.org/0000-0002-5795-1144","observed_orcids":["https://orcid.org/0000-0002-5795-1144"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark M. Walsh","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0000-0002-5795-1144","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073802278","display_name":"Mark D. Fox","orcid":"https://orcid.org/0000-0002-4544-2350","observed_orcids":["https://orcid.org/0000-0002-4544-2350"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark D. Fox","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041612225","display_name":"Ernest Eugene Moore","orcid":"https://orcid.org/0000-0002-0419-4848","observed_orcids":["https://orcid.org/0000-0002-0419-4848"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ernest E. Moore","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0000-0002-0419-4848","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068867603","display_name":"Jeffrey L. Johnson","orcid":"https://orcid.org/0009-0003-3849-0746","observed_orcids":["https://orcid.org/0009-0003-3849-0746"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey L. Johnson","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022908607","display_name":"Connor M. Bunch","orcid":"https://orcid.org/0000-0002-8566-7001","observed_orcids":["https://orcid.org/0000-0002-8566-7001"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Connor M. Bunch","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058352251","display_name":"Joseph B Miller","orcid":"https://orcid.org/0000-0002-9451-1359","observed_orcids":["https://orcid.org/0000-0002-9451-1359"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph B. Miller","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0000-0002-9451-1359","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110504359","display_name":"Ileana Lopez\u2010Plaza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ileana Lopez-Plaza","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051869320","display_name":"Rachel L. Brancamp","orcid":"https://orcid.org/0000-0002-5054-0991","observed_orcids":["https://orcid.org/0000-0002-5054-0991"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel L. Brancamp","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0000-0002-5054-0991","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110093326","display_name":"Dan A. Waxman","orcid":"https://orcid.org/0009-0008-0967-0605","observed_orcids":["https://orcid.org/0009-0008-0967-0605"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan A. Waxman","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0009-0008-0967-0605","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108812562","display_name":"Scott G. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott G. Thomas","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046637252","display_name":"Daniel H. Fulkerson","orcid":"https://orcid.org/0000-0003-4624-971X","observed_orcids":["https://orcid.org/0000-0003-4624-971X"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel H. Fulkerson","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111249233","display_name":"Emmanuel J. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emmanuel J. Thomas","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102655145","display_name":"Hassaan A. Khan","orcid":"https://orcid.org/0009-0006-7431-1946","observed_orcids":["https://orcid.org/0009-0006-7431-1946"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hassaan A. Khan","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0009-0006-7431-1946","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113329194","display_name":"Sufyan K. Zackariya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sufyan K. Zackariya","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068850078","display_name":"Mahmoud D. Al-Fadhl","orcid":"https://orcid.org/0000-0002-3481-1966","observed_orcids":["https://orcid.org/0000-0002-3481-1966"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahmoud D. Al-Fadhl","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0000-0002-3481-1966","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112460696","display_name":"Saniya K. Zackariya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saniya K. Zackariya","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040603113","display_name":"Samuel Thomas","orcid":"https://orcid.org/0009-0004-1644-7074","observed_orcids":["https://orcid.org/0009-0004-1644-7074"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel J. Thomas","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044634460","display_name":"Michael W. Aboukhaled","orcid":"https://orcid.org/0009-0001-1244-072X","observed_orcids":["https://orcid.org/0009-0001-1244-072X"]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael W. Aboukhaled","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA"],"raw_orcid":"https://orcid.org/0009-0001-1244-072X","affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine\u2014South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]},{"author_position":"last","author":{"id":null,"display_name":"the Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134870","display_name":"Indiana University South Bend","ror":"https://ror.org/02s1hvj37","country_code":"US","type":"education","lineage":["https://openalex.org/I4210134870","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"the Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group","raw_affiliation_strings":["Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine-South Bend, South Bend, IN 46617, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Futile Indicators for Stopping Transfusion in Trauma (FISTT) Collaborative Group, Indiana University School of Medicine-South Bend, South Bend, IN 46617, USA","institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041923386"],"corresponding_institution_ids":["https://openalex.org/I4210134870","https://openalex.org/I4394709130"],"apc_list":{"value":2600,"currency":"CHF","value_usd":2955},"apc_paid":{"value":2600,"currency":"CHF","value_usd":2955},"fwci":0.7757,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.62830061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"13","issue":"16","first_page":"4684","last_page":"4684"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.03579999879002571,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11467","display_name":"Trauma and Emergency Care Studies","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/massive-transfusion","display_name":"massive transfusion","score":0.8040000200271606},{"id":"https://openalex.org/keywords/traumatic-hemorrhage","display_name":"traumatic hemorrhage","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hemorrhagic-shock","display_name":"hemorrhagic shock","score":0.9449999928474426},{"id":"https://openalex.org/keywords/blood-shortage","display_name":"blood shortage","score":0.6940000057220459},{"id":"https://openalex.org/keywords/viscoelastic-parameters","display_name":"viscoelastic parameters","score":0.6110000014305115},{"id":"https://openalex.org/keywords/scoring-system","display_name":"scoring system","score":0.5210000276565552},{"id":"https://openalex.org/keywords/whole-blood-transfusion","display_name":"whole blood transfusion","score":0.6299999952316284},{"id":"https://openalex.org/keywords/urban-trauma","display_name":"urban trauma","score":0.4830000102519989}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9285226464271545},{"id":"https://openalex.org/C2778165595","wikidata":"https://www.wikidata.org/wiki/Q5491454","display_name":"Resuscitation","level":2,"score":0.7733038067817688},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.7256398797035217},{"id":"https://openalex.org/C2777950569","wikidata":"https://www.wikidata.org/wiki/Q17021836","display_name":"Stewardship (theology)","level":3,"score":0.43021702766418457},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.4213804602622986},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.41958245635032654},{"id":"https://openalex.org/C2993366118","wikidata":"https://www.wikidata.org/wiki/Q1320276","display_name":"Hemorrhagic shock","level":3,"score":0.4124097526073456},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.30688923597335815},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2044171392917633},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/jcm13164684","doi":"https://doi.org/10.3390/jcm13164684","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164684","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4684/pdf?version=1723199631","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11355875","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11355875","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11355875/pdf/jcm-13-04684.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmid:39200824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39200824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:scholarworks.indianapolis.iu.edu:1805/43972","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1805/43972","pdf_url":"https://scholarworks.indianapolis.iu.edu/bitstreams/9eea6e73-2bd8-4205-9138-2efbad4441e6/download","source":{"id":"https://openalex.org/S4306400987","display_name":"IUScholarWorks (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3390/jcm13164684","doi":"https://doi.org/10.3390/jcm13164684","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm13164684","pdf_url":"https://www.mdpi.com/2077-0383/13/16/4684/pdf?version=1723199631","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401484392.pdf","grobid_xml":"https://content.openalex.org/works/W4401484392.grobid-xml"},"referenced_works_count":180,"referenced_works":["https://openalex.org/W350585951","https://openalex.org/W1524466537","https://openalex.org/W1544743270","https://openalex.org/W1882687129","https://openalex.org/W1904245217","https://openalex.org/W1926685310","https://openalex.org/W1965011920","https://openalex.org/W1966172124","https://openalex.org/W1976085421","https://openalex.org/W1981714421","https://openalex.org/W2004298154","https://openalex.org/W2005358181","https://openalex.org/W2008233100","https://openalex.org/W2016934435","https://openalex.org/W2018161340","https://openalex.org/W2018525094","https://openalex.org/W2026535276","https://openalex.org/W2026926630","https://openalex.org/W2038378391","https://openalex.org/W2041110264","https://openalex.org/W2046976003","https://openalex.org/W2048075299","https://openalex.org/W2052051058","https://openalex.org/W2056257490","https://openalex.org/W2057251172","https://openalex.org/W2063854911","https://openalex.org/W2070366986","https://openalex.org/W2071903196","https://openalex.org/W2073315399","https://openalex.org/W2077008458","https://openalex.org/W2082479261","https://openalex.org/W2084280207","https://openalex.org/W2085024400","https://openalex.org/W2086514018","https://openalex.org/W2087391363","https://openalex.org/W2088395198","https://openalex.org/W2089129241","https://openalex.org/W2091129382","https://openalex.org/W2092158875","https://openalex.org/W2104850224","https://openalex.org/W2119506222","https://openalex.org/W2127379488","https://openalex.org/W2133226878","https://openalex.org/W2137591871","https://openalex.org/W2142472354","https://openalex.org/W2156938534","https://openalex.org/W2157314996","https://openalex.org/W2159708171","https://openalex.org/W2163169165","https://openalex.org/W2178434425","https://openalex.org/W2204494898","https://openalex.org/W2232998350","https://openalex.org/W2253667090","https://openalex.org/W2295828145","https://openalex.org/W2316771574","https://openalex.org/W2331792724","https://openalex.org/W2341975075","https://openalex.org/W2343558750","https://openalex.org/W2410894778","https://openalex.org/W2430704969","https://openalex.org/W2473136558","https://openalex.org/W2519131163","https://openalex.org/W2598456297","https://openalex.org/W2735170016","https://openalex.org/W2738279333","https://openalex.org/W2755279753","https://openalex.org/W2768137696","https://openalex.org/W2783348064","https://openalex.org/W2783799442","https://openalex.org/W2794394975","https://openalex.org/W2798210309","https://openalex.org/W2801161899","https://openalex.org/W2804609267","https://openalex.org/W2842106323","https://openalex.org/W2846419763","https://openalex.org/W2887734090","https://openalex.org/W2889582355","https://openalex.org/W2895367375","https://openalex.org/W2896626774","https://openalex.org/W2904347322","https://openalex.org/W2907165236","https://openalex.org/W2938462293","https://openalex.org/W2945752094","https://openalex.org/W2972225317","https://openalex.org/W2980833278","https://openalex.org/W2990174568","https://openalex.org/W2996788226","https://openalex.org/W3010832985","https://openalex.org/W3011070433","https://openalex.org/W3012690896","https://openalex.org/W3015688864","https://openalex.org/W3020023975","https://openalex.org/W3021588373","https://openalex.org/W3026628563","https://openalex.org/W3031572816","https://openalex.org/W3037252086","https://openalex.org/W3037935766","https://openalex.org/W3039544106","https://openalex.org/W3047907463","https://openalex.org/W3088762507","https://openalex.org/W3098592597","https://openalex.org/W3099645908","https://openalex.org/W3111755222","https://openalex.org/W3115840276","https://openalex.org/W3118545496","https://openalex.org/W3123497531","https://openalex.org/W3123786131","https://openalex.org/W3124046584","https://openalex.org/W3126579648","https://openalex.org/W3129379324","https://openalex.org/W3132140525","https://openalex.org/W3134016656","https://openalex.org/W3152414427","https://openalex.org/W3159466199","https://openalex.org/W3169887039","https://openalex.org/W3177752229","https://openalex.org/W3178282441","https://openalex.org/W3180174496","https://openalex.org/W3185014489","https://openalex.org/W3196788678","https://openalex.org/W3206761275","https://openalex.org/W3212910472","https://openalex.org/W3214522378","https://openalex.org/W4205353718","https://openalex.org/W4206308706","https://openalex.org/W4210405574","https://openalex.org/W4210648798","https://openalex.org/W4210917725","https://openalex.org/W4220760129","https://openalex.org/W4220760785","https://openalex.org/W4220776075","https://openalex.org/W4220899685","https://openalex.org/W4224217842","https://openalex.org/W4224947684","https://openalex.org/W4225664306","https://openalex.org/W4226368175","https://openalex.org/W4229057298","https://openalex.org/W4282939860","https://openalex.org/W4283207635","https://openalex.org/W4283391965","https://openalex.org/W4284883195","https://openalex.org/W4285727534","https://openalex.org/W4292731321","https://openalex.org/W4293063868","https://openalex.org/W4293821300","https://openalex.org/W4295979476","https://openalex.org/W4297963393","https://openalex.org/W4304632467","https://openalex.org/W4306294803","https://openalex.org/W4309710906","https://openalex.org/W4310421930","https://openalex.org/W4317234240","https://openalex.org/W4317927748","https://openalex.org/W4318919027","https://openalex.org/W4318923943","https://openalex.org/W4318935414","https://openalex.org/W4319825690","https://openalex.org/W4321003837","https://openalex.org/W4321376860","https://openalex.org/W4323921261","https://openalex.org/W4327905211","https://openalex.org/W4361190312","https://openalex.org/W4362522965","https://openalex.org/W4364352664","https://openalex.org/W4365503534","https://openalex.org/W4366242343","https://openalex.org/W4367309672","https://openalex.org/W4367600458","https://openalex.org/W4367601127","https://openalex.org/W4377694155","https://openalex.org/W4380927210","https://openalex.org/W4382918514","https://openalex.org/W4386172036","https://openalex.org/W4387012506","https://openalex.org/W4388657502","https://openalex.org/W4388831966","https://openalex.org/W4390022378","https://openalex.org/W4391310328","https://openalex.org/W4400329579","https://openalex.org/W4401222108"],"related_works":["https://openalex.org/W4412995407","https://openalex.org/W3214522378","https://openalex.org/W7204619783","https://openalex.org/W4293063868","https://openalex.org/W4367601127","https://openalex.org/W7155088688","https://openalex.org/W7128957684","https://openalex.org/W7213204513","https://openalex.org/W4406087340","https://openalex.org/W7212284936"],"abstract_inverted_index":{"The":[0,162,186],"reduction":[1,32],"in":[2,27,114,141,160,176,184],"the":[3,7,15,34,39,51,65,87,115,174,218,226,229],"blood":[4,22,26,35,42,71,129],"supply":[5,36,48],"following":[6],"2019":[8],"coronavirus":[9],"pandemic":[10],"has":[11,37,63,105],"been":[12,106],"exacerbated":[13],"by":[14,86],"increased":[16,68],"use":[17,251],"of":[18,33,41,57,89,136,164,173,182,188,192,220,231],"balanced":[19],"resuscitation":[20,233],"with":[21,54,212,236],"components":[23],"including":[24],"whole":[25],"urban":[28,58],"trauma":[29,59,78],"centers.":[30],"This":[31,61,81],"diminished":[38],"ability":[40],"banks":[43],"to":[44,49,110,168,178,248],"maintain":[45],"a":[46,107,170,197,205,243],"constant":[47],"meet":[50],"demands":[52],"associated":[53],"periodic":[55],"surges":[56],"resuscitation.":[60,138],"scarcity":[62],"highlighted":[64],"need":[66],"for":[67,199,208,217,234,246],"vigilance":[69],"through":[70],"product":[72],"stewardship,":[73],"particularly":[74],"among":[75],"severely":[76],"bleeding":[77],"patients":[79,235],"(SBTPs).":[80],"stewardship":[82],"can":[83,259],"be":[84],"enhanced":[85],"identification":[88],"reliable":[90,180,190],"clinical":[91],"and":[92,117,125,128,146,240,255],"laboratory":[93],"parameters":[94,127,181,191,257],"which":[95,121,152,156,202,258],"accurately":[96],"indicate":[97],"when":[98,210],"massive":[99],"transfusion":[100],"is":[101,148,167],"futile.":[102],"Consequently,":[103],"there":[104,147],"recent":[108],"attempt":[109],"develop":[111],"scoring":[112],"systems":[113],"prehospital":[116],"emergency":[118],"department":[119],"settings":[120],"include":[122],"clinical,":[123,253],"laboratory,":[124,254],"physiologic":[126],"products":[130],"per":[131],"hour":[132],"transfused":[133],"as":[134],"predictors":[135],"futile":[137,232],"Defining":[139],"futility":[140,159,183,193],"SBTPs,":[142],"however,":[143],"remains":[144],"unclear,":[145],"only":[149],"nascent":[150],"literature":[151,175,227],"defines":[153],"those":[154],"criteria":[155],"reliably":[157],"predict":[158],"SBTPs.":[161,185],"purpose":[163],"this":[165],"review":[166],"provide":[169,204],"focused":[171],"examination":[172],"order":[177],"define":[179,196,260],"knowledge":[187],"these":[189],"may":[194],"help":[195,249],"foundation":[198],"drawing":[200],"conclusions":[201],"will":[203],"clear":[206],"roadmap":[207,245],"traumatologists":[209],"confronted":[211],"SBTPs":[213],"who":[214],"are":[215],"candidates":[216],"declaration":[219],"futility.":[221,261],"Therefore,":[222],"we":[223,241],"systematically":[224],"reviewed":[225],"regarding":[228],"definition":[230],"trauma-induced":[237],"hemorrhagic":[238],"shock,":[239],"propose":[242],"concise":[244],"clinicians":[247],"them":[250],"well-defined":[252],"viscoelastic":[256]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-08-11T00:00:00"}