{"id":"https://openalex.org/W4401430268","doi":"https://doi.org/10.1080/17474086.2024.2389997","title":"Applications of artificial intelligence to myeloproliferative neoplasms: a narrative review","display_name":"Applications of artificial intelligence to myeloproliferative neoplasms: a narrative review","publication_year":2024,"publication_date":"2024-08-08","ids":{"openalex":"https://openalex.org/W4401430268","doi":"https://doi.org/10.1080/17474086.2024.2389997","pmid":"https://pubmed.ncbi.nlm.nih.gov/39114884","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11996228"},"language":"en","primary_location":{"id":"doi:10.1080/17474086.2024.2389997","doi":"https://doi.org/10.1080/17474086.2024.2389997","is_oa":true,"landing_page_url":"https://doi.org/10.1080/17474086.2024.2389997","pdf_url":null,"source":{"id":"https://openalex.org/S73682863","display_name":"Expert Review of Hematology","issn_l":"1747-4086","issn":["1747-4086","1747-4094"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Hematology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1080/17474086.2024.2389997","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091014069","display_name":"Andrew Srisuwananukorn","orcid":"https://orcid.org/0000-0002-8736-8726","observed_orcids":["https://orcid.org/0000-0002-8736-8726"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew Srisuwananukorn","raw_affiliation_strings":["Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA","institution_ids":["https://openalex.org/I2799885155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015161583","display_name":"Jordan Edward Krull","orcid":"https://orcid.org/0000-0001-6507-8085","observed_orcids":["https://orcid.org/0000-0001-6507-8085"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jordan E. Krull","raw_affiliation_strings":["Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA","institution_ids":["https://openalex.org/I2799885155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022408570","display_name":"Qin Ma","orcid":"https://orcid.org/0000-0002-3264-8392","observed_orcids":["https://orcid.org/0000-0002-3264-8392","https://orcid.org/0000-0001-6269-398X"]},"institutions":[{"id":"https://openalex.org/I2799885155","display_name":"The Ohio State University Comprehensive Cancer Center \u2013 Arthur G. James Cancer Hospital and Richard J. Solove Research Institute","ror":"https://ror.org/028t46f04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799885155","https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qin Ma","raw_affiliation_strings":["Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA","institution_ids":["https://openalex.org/I2799885155"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050360222","display_name":"Ping Zhang","orcid":"https://orcid.org/0000-0002-4601-0779","observed_orcids":["https://orcid.org/0000-0002-4601-0779"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Zhang","raw_affiliation_strings":["Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","Department of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, OH, USA","Translational Data Analytics Institute, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Translational Data Analytics Institute, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031626209","display_name":"Alexander T. Pearson","orcid":"https://orcid.org/0000-0003-2801-7456","observed_orcids":["https://orcid.org/0000-0003-2801-7456"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander T. Pearson","raw_affiliation_strings":["Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006372952","display_name":"Ronald Hoffman","orcid":"https://orcid.org/0000-0001-6564-6732","observed_orcids":["https://orcid.org/0000-0001-6564-6732"]},"institutions":[{"id":"https://openalex.org/I4390039328","display_name":"Tisch Cancer Institute","ror":"https://ror.org/0317dzj93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813","https://openalex.org/I4390039328","https://openalex.org/I98704320"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald Hoffman","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA","institution_ids":["https://openalex.org/I4390039328","https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5091014069"],"corresponding_institution_ids":["https://openalex.org/I2799885155"],"apc_list":null,"apc_paid":null,"fwci":0.4987,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.46246575,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"17","issue":"10","first_page":"669","last_page":"677"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.04019999876618385,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.8389999866485596},{"id":"https://openalex.org/keywords/myeloproliferative-neoplasms","display_name":"myeloproliferative neoplasms","score":1.0},{"id":"https://openalex.org/keywords/clinical-outcome-prediction","display_name":"clinical outcome prediction","score":0.7620000243186951},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.828000009059906},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.7870000004768372},{"id":"https://openalex.org/keywords/treatment-selection","display_name":"treatment selection","score":0.6669999957084656},{"id":"https://openalex.org/keywords/clinical-decision-support","display_name":"clinical decision support","score":0.6809999942779541},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6430000066757202},{"id":"https://openalex.org/keywords/drug-target-identification","display_name":"drug target identification","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8965268135070801},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.338081419467926}],"mesh":[{"descriptor_ui":"D000066491","descriptor_name":"Clinical Decision-Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009196","descriptor_name":"Myeloproliferative Disorders","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1080/17474086.2024.2389997","doi":"https://doi.org/10.1080/17474086.2024.2389997","is_oa":true,"landing_page_url":"https://doi.org/10.1080/17474086.2024.2389997","pdf_url":null,"source":{"id":"https://openalex.org/S73682863","display_name":"Expert Review of Hematology","issn_l":"1747-4086","issn":["1747-4086","1747-4094"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Hematology","raw_type":"journal-article"},{"id":"pmid:39114884","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39114884","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert review of hematology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11996228","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11996228","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11996228/pdf/nihms-2060710.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Expert Rev Hematol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1080/17474086.2024.2389997","doi":"https://doi.org/10.1080/17474086.2024.2389997","is_oa":true,"landing_page_url":"https://doi.org/10.1080/17474086.2024.2389997","pdf_url":null,"source":{"id":"https://openalex.org/S73682863","display_name":"Expert Review of Hematology","issn_l":"1747-4086","issn":["1747-4086","1747-4094"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Hematology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000865260","display_name":"Myeloproliferative Neoplasms-Research Consortium","funder_award_id":"P01CA108671","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306239","display_name":"Conquer Cancer Foundation","ror":"https://ror.org/027327e78"},{"id":"https://openalex.org/F4320306900","display_name":"Cancer Research Foundation","ror":"https://ror.org/052nngb38"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401430268.pdf","grobid_xml":"https://content.openalex.org/works/W4401430268.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W2010298229","https://openalex.org/W2058342200","https://openalex.org/W2127559749","https://openalex.org/W2620415343","https://openalex.org/W2761473139","https://openalex.org/W2949650786","https://openalex.org/W2989685001","https://openalex.org/W2995327724","https://openalex.org/W3010810358","https://openalex.org/W3044964811","https://openalex.org/W3087670258","https://openalex.org/W3127716924","https://openalex.org/W3132746250","https://openalex.org/W3136552952","https://openalex.org/W3136960503","https://openalex.org/W3157209223","https://openalex.org/W3173393692","https://openalex.org/W3180959755","https://openalex.org/W3206984067","https://openalex.org/W4213435390","https://openalex.org/W4283271244","https://openalex.org/W4283716970","https://openalex.org/W4309821706","https://openalex.org/W4310783782","https://openalex.org/W4312211610","https://openalex.org/W4318066502","https://openalex.org/W4327574712","https://openalex.org/W4327810158","https://openalex.org/W4363645706","https://openalex.org/W4378674294","https://openalex.org/W4379141171","https://openalex.org/W4382918945","https://openalex.org/W4383534950","https://openalex.org/W4384071683","https://openalex.org/W4385322266","https://openalex.org/W4386170929","https://openalex.org/W4387568471","https://openalex.org/W4389232090","https://openalex.org/W4389247899","https://openalex.org/W4389304091","https://openalex.org/W6910681941"],"related_works":["https://openalex.org/W7223264349","https://openalex.org/W4327621884","https://openalex.org/W4405763945","https://openalex.org/W7163549626","https://openalex.org/W7125643047","https://openalex.org/W4409098524","https://openalex.org/W4417021745","https://openalex.org/W4385667029","https://openalex.org/W4405050474","https://openalex.org/W4391486564"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Artificial":[1],"intelligence":[2],"(AI)":[3],"is":[4,119],"a":[5,183],"rapidly":[6],"growing":[7],"field":[8],"of":[9,22,24,55,80,192],"computational":[10],"research":[11,180],"with":[12,135,156],"the":[13,20,29,53,77,161,174,179,190],"potential":[14],"to":[15,97,108,133],"extract":[16],"nuanced":[17],"biomarkers":[18],"for":[19,28,31,34,52,170,186],"prediction":[21,30],"outcomes":[23,33],"interest.":[25],"AI":[26,50,92,124,142,171],"implementations":[27],"clinical":[32,57,137,149,194],"myeloproliferative":[35],"neoplasms":[36],"(MPNs)":[37],"are":[38,167],"currently":[39],"under":[40],"investigation.":[41],"AREAS":[42],"COVERED:":[43],"In":[44],"this":[45,165],"narrative":[46],"review,":[47],"we":[48],"discuss":[49],"investigations":[51,107,169],"improvement":[54],"MPN":[56,127,193],"care":[58,128],"utilizing":[59],"either":[60],"clinically":[61],"available":[62],"data":[63],"or":[64,105],"experimental":[65],"laboratory":[66],"findings.":[67],"Abstracts":[68],"and":[69,76,85,129],"manuscripts":[70],"were":[71],"identified":[72],"upon":[73],"querying":[74],"PubMed":[75],"American":[78],"Society":[79],"Hematology":[81],"conference":[82],"between":[83],"2000":[84],"2023.":[86],"Overall,":[87],"multidisciplinary":[88],"researchers":[89],"have":[90],"developed":[91,155,177],"methods":[93,125],"in":[94,126,164,172,189],"MPNs":[95],"attempting":[96],"improve":[98],"diagnostic":[99],"accuracy,":[100],"risk":[101],"prediction,":[102],"therapy":[103],"selection,":[104],"pre-clinical":[106],"identify":[109],"candidate":[110],"molecules":[111],"as":[112,148],"novel":[113],"therapeutic":[114],"agents.":[115],"EXPERT":[116],"OPINION:":[117],"It":[118],"our":[120],"expert":[121],"opinion":[122],"that":[123,141],"hematology":[130],"will":[131,144],"continue":[132],"grow":[134],"increasing":[136],"utility.":[138],"We":[139],"believe":[140],"models":[143],"assist":[145],"healthcare":[146],"workers":[147],"decision":[150],"support":[151],"tools":[152],"if":[153],"appropriately":[154],"AI-specific":[157],"regulatory":[158],"guidelines.":[159],"Though":[160],"reported":[162],"findings":[163],"review":[166],"early":[168],"MPNs,":[173],"collective":[175],"work":[176],"by":[178],"community":[181],"provides":[182],"promising":[184],"framework":[185],"improving":[187],"decision-making":[188],"future":[191],"care.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-08-09T00:00:00"}