{"id":"https://openalex.org/W4401428136","doi":"https://doi.org/10.1038/s41556-024-01468-x","title":"Spermidine is essential for fasting-mediated autophagy and longevity","display_name":"Spermidine is essential for fasting-mediated autophagy and longevity","publication_year":2024,"publication_date":"2024-08-08","ids":{"openalex":"https://openalex.org/W4401428136","doi":"https://doi.org/10.1038/s41556-024-01468-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/39117797","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11392816"},"language":"en","primary_location":{"id":"doi:10.1038/s41556-024-01468-x","doi":"https://doi.org/10.1038/s41556-024-01468-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41556-024-01468-x","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1038/s41556-024-01468-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024515933","display_name":"Sebastian J. Hofer","orcid":"https://orcid.org/0000-0002-0756-0014","observed_orcids":["https://orcid.org/0000-0002-0756-0014"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Sebastian J. Hofer","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Field of Excellence BioHealth, University of Graz, Graz, Austria","Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":"https://orcid.org/0000-0002-0756-0014","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002614931","display_name":"Ioanna Daskalaki","orcid":"https://orcid.org/0000-0002-2423-9660","observed_orcids":["https://orcid.org/0000-0002-2423-9660"]},"institutions":[{"id":"https://openalex.org/I142617266","display_name":"University of Crete","ror":"https://ror.org/00dr28g20","country_code":"GR","type":"education","lineage":["https://openalex.org/I142617266"]},{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]},{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Ioanna Daskalaki","raw_affiliation_strings":["Department of Biology, School of Sciences and Engineering, University of Crete, Heraklion, Greece","Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, School of Sciences and Engineering, University of Crete, Heraklion, Greece","institution_ids":["https://openalex.org/I142617266"]},{"raw_affiliation_string":"Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042365285","display_name":"Martina Bergmann","orcid":"https://orcid.org/0000-0002-1537-748X","observed_orcids":["https://orcid.org/0000-0002-1537-748X"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Martina Bergmann","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005136228","display_name":"Jasna Fri\u0161\u010di\u0107","orcid":"https://orcid.org/0000-0001-6136-1967","observed_orcids":["https://orcid.org/0000-0001-6136-1967"]},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jasna Fri\u0161\u010di\u0107","raw_affiliation_strings":["Department of Dermatology, Allergy and Venerology, University of L\u00fcbeck, L\u00fcbeck, Germany","Institute for Systemic Inflammation Research, University of L\u00fcbeck, L\u00fcbeck, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Allergy and Venerology, University of L\u00fcbeck, L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Institute for Systemic Inflammation Research, University of L\u00fcbeck, L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006218856","display_name":"Andreas Zimmermann","orcid":"https://orcid.org/0000-0003-2249-944X","observed_orcids":["https://orcid.org/0000-0003-2249-944X"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andreas Zimmermann","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Field of Excellence BioHealth, University of Graz, Graz, Austria","Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0003-2249-944X","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087254887","display_name":"Melanie I. Mueller","orcid":"https://orcid.org/0000-0002-7472-2677","observed_orcids":["https://orcid.org/0000-0002-7472-2677"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Melanie I. Mueller","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-7472-2677","affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091865962","display_name":"Mahmoud Abdellatif","orcid":"https://orcid.org/0000-0002-5042-9054","observed_orcids":["https://orcid.org/0000-0002-5042-9054"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Mahmoud Abdellatif","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Division of Cardiology, Medical University of Graz, Graz, Austria","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":"https://orcid.org/0000-0002-5042-9054","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Division of Cardiology, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070901525","display_name":"Raffaele Nicastro","orcid":"https://orcid.org/0000-0002-5420-2228","observed_orcids":["https://orcid.org/0000-0002-5420-2228"]},"institutions":[{"id":"https://openalex.org/I154338468","display_name":"University of Fribourg","ror":"https://ror.org/022fs9h90","country_code":"CH","type":"education","lineage":["https://openalex.org/I154338468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Raffaele Nicastro","raw_affiliation_strings":["Department of Biology, University of Fribourg, Fribourg, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-5420-2228","affiliations":[{"raw_affiliation_string":"Department of Biology, University of Fribourg, Fribourg, Switzerland","institution_ids":["https://openalex.org/I154338468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005380441","display_name":"Sarah Masser","orcid":"https://orcid.org/0000-0002-5195-0650","observed_orcids":["https://orcid.org/0000-0002-5195-0650"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Sarah Masser","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-5195-0650","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090572918","display_name":"Sylv\u00e8re Durand","orcid":"https://orcid.org/0000-0001-6356-1006","observed_orcids":["https://orcid.org/0000-0001-6356-1006"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylv\u00e8re Durand","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106360063","display_name":"Alexander Nartey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Alexander Nartey","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044749920","display_name":"Mara Waltenstorfer","orcid":"https://orcid.org/0000-0001-7541-8338","observed_orcids":["https://orcid.org/0000-0001-7541-8338"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Mara Waltenstorfer","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0001-7541-8338","affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106365732","display_name":"Sarah Enzenhofer","orcid":"https://orcid.org/0009-0006-7474-5226","observed_orcids":["https://orcid.org/0009-0006-7474-5226"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Sarah Enzenhofer","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0009-0006-7474-5226","affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116445846","display_name":"Isabella Faimann","orcid":"https://orcid.org/0009-0001-5897-3791","observed_orcids":["https://orcid.org/0009-0001-5897-3791"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Isabella Faimann","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076349757","display_name":"Verena Gschiel","orcid":"https://orcid.org/0000-0002-1090-9010","observed_orcids":["https://orcid.org/0000-0002-1090-9010"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Verena Gschiel","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-1090-9010","affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023182072","display_name":"Thomas Bajaj","orcid":"https://orcid.org/0000-0001-6153-6608","observed_orcids":["https://orcid.org/0000-0001-6153-6608"]},"institutions":[{"id":"https://openalex.org/I2799391451","display_name":"University Hospital Bonn","ror":"https://ror.org/01xnwqx93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799391451"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Bajaj","raw_affiliation_strings":["Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany","institution_ids":["https://openalex.org/I2799391451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026264708","display_name":"Christine Niemeyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799391451","display_name":"University Hospital Bonn","ror":"https://ror.org/01xnwqx93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799391451"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christine Niemeyer","raw_affiliation_strings":["Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany","institution_ids":["https://openalex.org/I2799391451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024082875","display_name":"Ilias Gkikas","orcid":"https://orcid.org/0000-0002-5899-551X","observed_orcids":["https://orcid.org/0000-0002-5899-551X"]},"institutions":[{"id":"https://openalex.org/I142617266","display_name":"University of Crete","ror":"https://ror.org/00dr28g20","country_code":"GR","type":"education","lineage":["https://openalex.org/I142617266"]},{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]},{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Ilias Gkikas","raw_affiliation_strings":["Department of Biology, School of Sciences and Engineering, University of Crete, Heraklion, Greece","Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, School of Sciences and Engineering, University of Crete, Heraklion, Greece","institution_ids":["https://openalex.org/I142617266"]},{"raw_affiliation_string":"Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044200378","display_name":"Lukas Pein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Lukas Pein","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010523895","display_name":"Giulia Cerrato","orcid":"https://orcid.org/0000-0003-2755-2860","observed_orcids":["https://orcid.org/0000-0003-2755-2860"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Giulia Cerrato","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hui Pan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Hui Pan","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086085551","display_name":"YongTian Liang","orcid":"https://orcid.org/0000-0002-5802-1045","observed_orcids":["https://orcid.org/0000-0002-5802-1045"]},"institutions":[{"id":"https://openalex.org/I4405268531","display_name":"NeuroCure Cluster of Excellence","ror":"https://ror.org/0188nsq50","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405268531"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"YongTian Liang","raw_affiliation_strings":["Cluster of Excellence, NeuroCure, Berlin, Germany","Institute for Biology and Genetics, Freie Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-5802-1045","affiliations":[{"raw_affiliation_string":"Cluster of Excellence, NeuroCure, Berlin, Germany","institution_ids":["https://openalex.org/I4405268531"]},{"raw_affiliation_string":"Institute for Biology and Genetics, Freie Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002970442","display_name":"Jelena Tadi\u0107","orcid":"https://orcid.org/0000-0001-6232-5378","observed_orcids":["https://orcid.org/0000-0001-6232-5378"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Jelena Tadic","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Field of Excellence BioHealth, University of Graz, Graz, Austria","Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0001-6232-5378","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037883749","display_name":"Andrea Jerkovic","orcid":"https://orcid.org/0000-0002-0442-712X","observed_orcids":["https://orcid.org/0000-0002-0442-712X"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andrea Jerkovic","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-0442-712X","affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003267360","display_name":"Fanny Aprahamian","orcid":"https://orcid.org/0000-0002-2457-8435","observed_orcids":["https://orcid.org/0000-0002-2457-8435"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fanny Aprahamian","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082983870","display_name":"Christine Reiser Robbins","orcid":"https://orcid.org/0000-0003-1976-9242","observed_orcids":["https://orcid.org/0000-0003-1976-9242"]},"institutions":[{"id":"https://openalex.org/I4405255059","display_name":"University of New Mexico Health Sciences Center","ror":"https://ror.org/02jvjmd55","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine E. Robbins","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I4405255059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060113824","display_name":"Nitharsshini Nirmalathasan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nitharsshini Nirmalathasan","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018751069","display_name":"Hansj\u00f6rg Habisch","orcid":"https://orcid.org/0000-0001-5537-506X","observed_orcids":["https://orcid.org/0000-0001-5537-506X"]},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Hansj\u00f6rg Habisch","raw_affiliation_strings":["Research Unit Integrative Structural Biology, Otto Loewi Research Center, Medicinal Chemistry, Medical University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0001-5537-506X","affiliations":[{"raw_affiliation_string":"Research Unit Integrative Structural Biology, Otto Loewi Research Center, Medicinal Chemistry, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106365733","display_name":"Elisabeth Annerer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Elisabeth Annerer","raw_affiliation_strings":["Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006051840","display_name":"Frederik Dethloff","orcid":"https://orcid.org/0009-0002-1114-2621","observed_orcids":["https://orcid.org/0009-0002-1114-2621"]},"institutions":[{"id":"https://openalex.org/I4210153965","display_name":"Max Planck Institute for Biology of Ageing","ror":"https://ror.org/04xx1tc24","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210153965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Frederik Dethloff","raw_affiliation_strings":["Max Planck Institute for Biology of Ageing, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Max Planck Institute for Biology of Ageing, Cologne, Germany","institution_ids":["https://openalex.org/I4210153965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071678095","display_name":"Michael Stumpe","orcid":"https://orcid.org/0000-0002-9443-9326","observed_orcids":["https://orcid.org/0000-0002-9443-9326"]},"institutions":[{"id":"https://openalex.org/I154338468","display_name":"University of Fribourg","ror":"https://ror.org/022fs9h90","country_code":"CH","type":"education","lineage":["https://openalex.org/I154338468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Stumpe","raw_affiliation_strings":["Department of Biology, University of Fribourg, Fribourg, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Fribourg, Fribourg, Switzerland","institution_ids":["https://openalex.org/I154338468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059510564","display_name":"Franziska Grundler","orcid":"https://orcid.org/0000-0002-4352-3990","observed_orcids":["https://orcid.org/0000-0002-4352-3990"]},"institutions":[{"id":"https://openalex.org/I4210138397","display_name":"Buchinger Wilhelmi","ror":"https://ror.org/04d2erj26","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210138397"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Franziska Grundler","raw_affiliation_strings":["Buchinger Wilhelmi Clinic, \u00dcberlingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Buchinger Wilhelmi Clinic, \u00dcberlingen, Germany","institution_ids":["https://openalex.org/I4210138397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081829222","display_name":"Fran\u00e7oise Wilhelmi de Toledo","orcid":"https://orcid.org/0000-0002-4578-5812","observed_orcids":["https://orcid.org/0000-0002-4578-5812"]},"institutions":[{"id":"https://openalex.org/I4210138397","display_name":"Buchinger Wilhelmi","ror":"https://ror.org/04d2erj26","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210138397"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fran\u00e7oise Wilhelmi de Toledo","raw_affiliation_strings":["Buchinger Wilhelmi Clinic, \u00dcberlingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Buchinger Wilhelmi Clinic, \u00dcberlingen, Germany","institution_ids":["https://openalex.org/I4210138397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073837547","display_name":"Daniel E. Heinz","orcid":"https://orcid.org/0000-0001-7103-9621","observed_orcids":["https://orcid.org/0000-0001-7103-9621"]},"institutions":[{"id":"https://openalex.org/I2799391451","display_name":"University Hospital Bonn","ror":"https://ror.org/01xnwqx93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799391451"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel E. Heinz","raw_affiliation_strings":["Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany","institution_ids":["https://openalex.org/I2799391451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022184505","display_name":"Daniela A. Koppold","orcid":"https://orcid.org/0000-0003-3367-3327","observed_orcids":["https://orcid.org/0000-0003-3367-3327"]},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210154591","display_name":"Immanuel Krankenhaus","ror":"https://ror.org/055z45c63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210154591"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniela A. Koppold","raw_affiliation_strings":["Department of Internal Medicine and Nature-based Therapies, Immanuel Hospital Berlin, Berlin, Germany","Department of Pediatrics, Division of Oncology and Hematology, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Berlin, Germany","Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Nature-based Therapies, Immanuel Hospital Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4210154591"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Oncology and Hematology, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany","institution_ids":["https://openalex.org/I75951250","https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034511120","display_name":"Anika Rajput Khokhar","orcid":"https://orcid.org/0000-0002-0135-9643","observed_orcids":["https://orcid.org/0000-0002-0135-9643"]},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anika Rajput Khokhar","raw_affiliation_strings":["Department of Dermatology, Venereology and Allergology, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Berlin, Germany","Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0135-9643","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Venereology and Allergology, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany","institution_ids":["https://openalex.org/I75951250","https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020497141","display_name":"Andreas Michalsen","orcid":"https://orcid.org/0000-0002-9145-7246","observed_orcids":["https://orcid.org/0000-0002-9145-7246"]},"institutions":[{"id":"https://openalex.org/I4210154591","display_name":"Immanuel Krankenhaus","ror":"https://ror.org/055z45c63","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210154591"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andreas Michalsen","raw_affiliation_strings":["Department of Internal Medicine and Nature-based Therapies, Immanuel Hospital Berlin, Berlin, Germany","Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Nature-based Therapies, Immanuel Hospital Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4210154591"]},{"raw_affiliation_string":"Institute of Social Medicine, Epidemiology and Health Economics, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t, Charit\u00e9-Universit\u00e4tsmedizin, Berlin, Germany","institution_ids":["https://openalex.org/I75951250","https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067997007","display_name":"Norbert Joachim Tripolt","orcid":"https://orcid.org/0000-0002-7566-2047","observed_orcids":["https://orcid.org/0000-0002-7566-2047"]},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Norbert J. Tripolt","raw_affiliation_strings":["Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]},{"raw_affiliation_string":"Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056821482","display_name":"Harald Sourij","orcid":"https://orcid.org/0000-0003-3510-9594","observed_orcids":["https://orcid.org/0000-0003-3510-9594"]},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Harald Sourij","raw_affiliation_strings":["Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]},{"raw_affiliation_string":"Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023877066","display_name":"Thomas Rudolf Pieber","orcid":"https://orcid.org/0000-0003-3554-0405","observed_orcids":["https://orcid.org/0000-0003-3554-0405"]},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]},{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas R. Pieber","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","HEALTH - Institute for Biomedical Research and Technologies, Joanneum Research Forschungsgesellschaft, Graz, Austria","Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]},{"raw_affiliation_string":"HEALTH - Institute for Biomedical Research and Technologies, Joanneum Research Forschungsgesellschaft, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]},{"raw_affiliation_string":"Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rafael de Cabo","orcid":"https://orcid.org/0000-0002-3354-2442","observed_orcids":["https://orcid.org/0000-0002-3354-2442"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafael de Cabo","raw_affiliation_strings":["Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-3354-2442","affiliations":[{"raw_affiliation_string":"Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067712370","display_name":"Mark A. McCormick","orcid":"https://orcid.org/0000-0002-4916-8280","observed_orcids":["https://orcid.org/0000-0002-4916-8280"]},"institutions":[{"id":"https://openalex.org/I4405255059","display_name":"University of New Mexico Health Sciences Center","ror":"https://ror.org/02jvjmd55","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark A. McCormick","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of New Mexico Health Sciences Center, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I4405255059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022216027","display_name":"Christoph Magnes","orcid":"https://orcid.org/0000-0002-5153-7444","observed_orcids":["https://orcid.org/0000-0002-5153-7444"]},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christoph Magnes","raw_affiliation_strings":["HEALTH - Institute for Biomedical Research and Technologies, Joanneum Research Forschungsgesellschaft, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-5153-7444","affiliations":[{"raw_affiliation_string":"HEALTH - Institute for Biomedical Research and Technologies, Joanneum Research Forschungsgesellschaft, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056768522","display_name":"Oliver Kepp","orcid":"https://orcid.org/0000-0002-6081-9558","observed_orcids":["https://orcid.org/0000-0002-6081-9558"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Oliver Kepp","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":"https://orcid.org/0000-0002-6081-9558","affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060883946","display_name":"J\u00f6rn Dengjel","orcid":"https://orcid.org/0000-0002-9453-4614","observed_orcids":["https://orcid.org/0000-0002-9453-4614"]},"institutions":[{"id":"https://openalex.org/I154338468","display_name":"University of Fribourg","ror":"https://ror.org/022fs9h90","country_code":"CH","type":"education","lineage":["https://openalex.org/I154338468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Joern Dengjel","raw_affiliation_strings":["Department of Biology, University of Fribourg, Fribourg, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-9453-4614","affiliations":[{"raw_affiliation_string":"Department of Biology, University of Fribourg, Fribourg, Switzerland","institution_ids":["https://openalex.org/I154338468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047265098","display_name":"Stephan J. Sigrist","orcid":"https://orcid.org/0000-0002-1698-5815","observed_orcids":["https://orcid.org/0000-0002-1698-5815"]},"institutions":[{"id":"https://openalex.org/I4405268531","display_name":"NeuroCure Cluster of Excellence","ror":"https://ror.org/0188nsq50","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405268531"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan J. Sigrist","raw_affiliation_strings":["Cluster of Excellence, NeuroCure, Berlin, Germany","Institute for Biology and Genetics, Freie Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1698-5815","affiliations":[{"raw_affiliation_string":"Cluster of Excellence, NeuroCure, Berlin, Germany","institution_ids":["https://openalex.org/I4405268531"]},{"raw_affiliation_string":"Institute for Biology and Genetics, Freie Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030860744","display_name":"Nils C. Gassen","orcid":"https://orcid.org/0000-0002-4265-3398","observed_orcids":["https://orcid.org/0000-0002-4265-3398"]},"institutions":[{"id":"https://openalex.org/I2799391451","display_name":"University Hospital Bonn","ror":"https://ror.org/01xnwqx93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799391451"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nils C. Gassen","raw_affiliation_strings":["Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany"],"raw_orcid":"https://orcid.org/0000-0002-4265-3398","affiliations":[{"raw_affiliation_string":"Neurohomeostasis Research Group, Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany","institution_ids":["https://openalex.org/I2799391451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082405402","display_name":"Simon Sedej","orcid":"https://orcid.org/0000-0002-4419-6821","observed_orcids":["https://orcid.org/0000-0002-4419-6821"]},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]},{"id":"https://openalex.org/I37696226","display_name":"University of Maribor","ror":"https://ror.org/01d5jce07","country_code":"SI","type":"education","lineage":["https://openalex.org/I37696226"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT","SI"],"is_corresponding":false,"raw_author_name":"Simon Sedej","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Division of Cardiology, Medical University of Graz, Graz, Austria","Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia"],"raw_orcid":"https://orcid.org/0000-0002-4419-6821","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Division of Cardiology, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]},{"raw_affiliation_string":"Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia","institution_ids":["https://openalex.org/I37696226"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065508395","display_name":"Tobias Madl","orcid":"https://orcid.org/0000-0002-9725-5231","observed_orcids":["https://orcid.org/0000-0002-9725-5231"]},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Tobias Madl","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Research Unit Integrative Structural Biology, Otto Loewi Research Center, Medicinal Chemistry, Medical University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-9725-5231","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Research Unit Integrative Structural Biology, Otto Loewi Research Center, Medicinal Chemistry, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037927525","display_name":"Claudio DE VIRGILIO","orcid":"https://orcid.org/0000-0001-8826-4323","observed_orcids":["https://orcid.org/0000-0001-8826-4323"]},"institutions":[{"id":"https://openalex.org/I154338468","display_name":"University of Fribourg","ror":"https://ror.org/022fs9h90","country_code":"CH","type":"education","lineage":["https://openalex.org/I154338468"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Claudio De Virgilio","raw_affiliation_strings":["Department of Biology, University of Fribourg, Fribourg, Switzerland"],"raw_orcid":"https://orcid.org/0000-0001-8826-4323","affiliations":[{"raw_affiliation_string":"Department of Biology, University of Fribourg, Fribourg, Switzerland","institution_ids":["https://openalex.org/I154338468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005914773","display_name":"Ulrich Stelzl","orcid":"https://orcid.org/0000-0003-2500-3585","observed_orcids":["https://orcid.org/0000-0003-2500-3585"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ulrich Stelzl","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Field of Excellence BioHealth, University of Graz, Graz, Austria","Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0003-2500-3585","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035589285","display_name":"Markus H. Hoffmann","orcid":"https://orcid.org/0000-0001-9698-9922","observed_orcids":["https://orcid.org/0000-0001-9698-9922"]},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Markus H. Hoffmann","raw_affiliation_strings":["Department of Dermatology, Allergy and Venerology, University of L\u00fcbeck, L\u00fcbeck, Germany","Institute for Systemic Inflammation Research, University of L\u00fcbeck, L\u00fcbeck, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Allergy and Venerology, University of L\u00fcbeck, L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]},{"raw_affiliation_string":"Institute for Systemic Inflammation Research, University of L\u00fcbeck, L\u00fcbeck, Germany","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018303103","display_name":"Tobias Eisenberg","orcid":"https://orcid.org/0000-0003-3559-1130","observed_orcids":["https://orcid.org/0000-0003-3559-1130"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Tobias Eisenberg","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria","Field of Excellence BioHealth, University of Graz, Graz, Austria","Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0003-3559-1130","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071420074","display_name":"Nektarios Tavernarakis","orcid":"https://orcid.org/0000-0002-5253-1466","observed_orcids":["https://orcid.org/0000-0002-5253-1466"]},"institutions":[{"id":"https://openalex.org/I142617266","display_name":"University of Crete","ror":"https://ror.org/00dr28g20","country_code":"GR","type":"education","lineage":["https://openalex.org/I142617266"]},{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]},{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Nektarios Tavernarakis","raw_affiliation_strings":["Division of Basic Sciences, School of Medicine, University of Crete, Heraklion, Greece. tavernarakis@imbb.forth.gr","Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece. tavernarakis@imbb.forth.gr","Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology \u2013 Hellas, Heraklion, Greece"],"raw_orcid":"https://orcid.org/0000-0002-5253-1466","affiliations":[{"raw_affiliation_string":"Division of Basic Sciences, School of Medicine, University of Crete, Heraklion, Greece. tavernarakis@imbb.forth.gr","institution_ids":["https://openalex.org/I142617266"]},{"raw_affiliation_string":"Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Greece. tavernarakis@imbb.forth.gr","institution_ids":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]},{"raw_affiliation_string":"Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology \u2013 Hellas, Heraklion, Greece","institution_ids":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075296559","display_name":"Guido Kroemer","orcid":"https://orcid.org/0000-0002-9334-4405","observed_orcids":["https://orcid.org/0000-0002-9334-4405"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I185839726","display_name":"Institut Universitaire de France","ror":"https://ror.org/055khg266","country_code":"FR","type":"education","lineage":["https://openalex.org/I185839726"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210092322","display_name":"Centre de Recherche des Cordeliers","ror":"https://ror.org/00dmms154","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210102325","display_name":"H\u00f4pital Europ\u00e9en Georges-Pompidou","ror":"https://ror.org/016vx5156","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210120235"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Guido Kroemer","raw_affiliation_strings":["Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France. kroemer@orange.fr","Institut du Cancer Paris CARPEM, Department of Biology, H\u00f4pital Europ\u00e9en Georges Pompidou, AP-HP, Paris, France. kroemer@orange.fr","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France. kroemer@orange.fr","Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France"],"raw_orcid":"https://orcid.org/0000-0002-9334-4405","affiliations":[{"raw_affiliation_string":"Centre de Recherche des Cordeliers, \u00c9quipe Labellis\u00e9e par la Ligue Contre le Cancer, Universit\u00e9 de Paris Cit\u00e9, Sorbonne Universit\u00e9, Inserm U1138, Institut Universitaire de France, Paris, France. kroemer@orange.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210092322"]},{"raw_affiliation_string":"Institut du Cancer Paris CARPEM, Department of Biology, H\u00f4pital Europ\u00e9en Georges Pompidou, AP-HP, Paris, France. kroemer@orange.fr","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210102325"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France. kroemer@orange.fr","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]},{"raw_affiliation_string":"Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Universit\u00e9 Paris Saclay, Villejuif, France","institution_ids":["https://openalex.org/I277688954","https://openalex.org/I2801843802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078054009","display_name":"Frank Madeo","orcid":"https://orcid.org/0000-0002-5070-1329","observed_orcids":["https://orcid.org/0000-0002-5070-1329"]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I4210117258","display_name":"BioTechMed-Graz","ror":"https://ror.org/02jfbm483","country_code":"AT","type":"facility","lineage":["https://openalex.org/I4210117258"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Frank Madeo","raw_affiliation_strings":["BioTechMed Graz, Graz, Austria. frank.madeo@uni-graz.at","Field of Excellence BioHealth, University of Graz, Graz, Austria. frank.madeo@uni-graz.at","Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria. frank.madeo@uni-graz.at","BioTechMed Graz, Graz, Austria"],"raw_orcid":"https://orcid.org/0000-0002-5070-1329","affiliations":[{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria. frank.madeo@uni-graz.at","institution_ids":["https://openalex.org/I4210117258"]},{"raw_affiliation_string":"Field of Excellence BioHealth, University of Graz, Graz, Austria. frank.madeo@uni-graz.at","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria. frank.madeo@uni-graz.at","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]},{"raw_affiliation_string":"BioTechMed Graz, Graz, Austria","institution_ids":["https://openalex.org/I4210117258"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":31,"corresponding_author_ids":["https://openalex.org/A5071420074","https://openalex.org/A5075296559","https://openalex.org/A5078054009"],"corresponding_institution_ids":["https://openalex.org/I142617266","https://openalex.org/I154526488","https://openalex.org/I15766117","https://openalex.org/I185839726","https://openalex.org/I204730241","https://openalex.org/I277688954","https://openalex.org/I2801843802","https://openalex.org/I39804081","https://openalex.org/I4210092322","https://openalex.org/I4210097159","https://openalex.org/I4210102325","https://openalex.org/I4210105723","https://openalex.org/I4210108044","https://openalex.org/I4210117258","https://openalex.org/I8901234"],"apc_list":{"value":12290,"currency":"USD","value_usd":12290},"apc_paid":{"value":12290,"currency":"USD","value_usd":12290},"fwci":21.5937,"has_fulltext":false,"cited_by_count":179,"citation_normalized_percentile":{"value":0.99561018,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"26","issue":"9","first_page":"1571","last_page":"1584"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.8877000212669373,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.8877000212669373,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11924","display_name":"Polyamine Metabolism and Applications","score":0.09000000357627869,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.015799999237060547,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spermidine","display_name":"spermidine","score":1.0},{"id":"https://openalex.org/keywords/polyamine-metabolism","display_name":"polyamine metabolism","score":0.7179999947547913},{"id":"https://openalex.org/keywords/fasting","display_name":"fasting","score":0.7059999704360962},{"id":"https://openalex.org/keywords/caloric-restriction","display_name":"caloric restriction","score":0.9649999737739563},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/longevity","display_name":"longevity","score":0.8519999980926514},{"id":"https://openalex.org/keywords/healthspan","display_name":"healthspan","score":0.9309999942779541},{"id":"https://openalex.org/keywords/eif5a","display_name":"eIF5A","score":0.7789999842643738},{"id":"https://openalex.org/keywords/hypusination","display_name":"hypusination","score":0.9100000262260437},{"id":"https://openalex.org/keywords/polyamine-synthesis-inhibition","display_name":"polyamine biosynthesis inhibition","score":0.5820000171661377},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.9369999766349792},{"id":"https://openalex.org/keywords/anti-arthritic-activity","display_name":"anti-arthritic activity","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lifespan-extension","display_name":"lifespan extension","score":0.5260000228881836}],"concepts":[{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.9161317944526672},{"id":"https://openalex.org/C2777497464","wikidata":"https://www.wikidata.org/wiki/Q418834","display_name":"Spermidine","level":3,"score":0.8985965251922607},{"id":"https://openalex.org/C2776759703","wikidata":"https://www.wikidata.org/wiki/Q1066907","display_name":"Longevity","level":2,"score":0.8276703357696533},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7174004316329956},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4019553065299988},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36836355924606323},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21322962641716003},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07603374123573303},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07136717438697815},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.046455442905426025}],"mesh":[{"descriptor_ui":"D000097574","descriptor_name":"Eukaryotic Translation Initiation Factor 5A","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005215","descriptor_name":"Fasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008136","descriptor_name":"Longevity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010448","descriptor_name":"Peptide Initiation Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010448","descriptor_name":"Peptide Initiation Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013095","descriptor_name":"Spermidine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013095","descriptor_name":"Spermidine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D031204","descriptor_name":"Caloric Restriction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41556-024-01468-x","doi":"https://doi.org/10.1038/s41556-024-01468-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41556-024-01468-x","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11392816","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11392816","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Cell Biol","raw_type":"Text"},{"id":"pmid:39117797","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39117797","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04888817v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04888817","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Cell Biology, 2024, 26 (9), pp.1571-1584. &#x27E8;10.1038/s41556-024-01468-x&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/s41556-024-01468-x","doi":"https://doi.org/10.1038/s41556-024-01468-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41556-024-01468-x","pdf_url":null,"source":{"id":"https://openalex.org/S151741590","display_name":"Nature Cell Biology","issn_l":"1465-7392","issn":["1465-7392","1476-4679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Cell Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1584703871","display_name":"Next-generation phenotypic screening for oncological applications","funder_award_id":"ANR-21-ESRE-0028","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G1780931065","display_name":"Amino acid signaling and growth control in yeast","funder_award_id":"166474","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G2129363707","display_name":null,"funder_award_id":"672032","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3620370544","display_name":"EXC 2167: Pr\u00e4zisionsmedizin f\u00fcr Chronische Entz\u00fcndungserkrankungen (PMI)","funder_award_id":"390884018","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3832214737","display_name":null,"funder_award_id":"SI 849/14-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4376162972","display_name":"Stimulus- and time-dependent protein dynamics in autophagy analyzed by quantitative mass spectrometry","funder_award_id":"184781","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G5324368231","display_name":null,"funder_award_id":"FOR2886/2-TP08","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7763750272","display_name":"Amino Acid Signaling and Growth Control in Yeast","funder_award_id":"184671","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8538166538","display_name":"Universit\u00e9 de Paris","funder_award_id":"ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G8690818240","display_name":null,"funder_award_id":"310030","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G9000908223","display_name":"Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.","funder_award_id":"P20GM121176","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320325582","display_name":"Karl-Franzens-Universit\u00e4t Graz","ror":"https://ror.org/01faaaf77"},{"id":"https://openalex.org/F4320326239","display_name":"Medizinische Universit\u00e4t Graz","ror":"https://ror.org/02n0bts35"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":115,"referenced_works":["https://openalex.org/W115026104","https://openalex.org/W1513618424","https://openalex.org/W1614347411","https://openalex.org/W1921244251","https://openalex.org/W1944127002","https://openalex.org/W1963871367","https://openalex.org/W1979098269","https://openalex.org/W1985046929","https://openalex.org/W1992654016","https://openalex.org/W2006022142","https://openalex.org/W2011580247","https://openalex.org/W2012418095","https://openalex.org/W2013865593","https://openalex.org/W2021632384","https://openalex.org/W2038120788","https://openalex.org/W2045200845","https://openalex.org/W2045611938","https://openalex.org/W2046989794","https://openalex.org/W2050532980","https://openalex.org/W2052722944","https://openalex.org/W2064609969","https://openalex.org/W2067837318","https://openalex.org/W2074037083","https://openalex.org/W2077083630","https://openalex.org/W2077612844","https://openalex.org/W2081465448","https://openalex.org/W2100347223","https://openalex.org/W2117296173","https://openalex.org/W2120925033","https://openalex.org/W2121211842","https://openalex.org/W2126415488","https://openalex.org/W2130008571","https://openalex.org/W2130682212","https://openalex.org/W2132247100","https://openalex.org/W2134138119","https://openalex.org/W2138138136","https://openalex.org/W2150420891","https://openalex.org/W2154046032","https://openalex.org/W2157765869","https://openalex.org/W2162670203","https://openalex.org/W2166957980","https://openalex.org/W2167279371","https://openalex.org/W2255001343","https://openalex.org/W2419653009","https://openalex.org/W2440558121","https://openalex.org/W2473146109","https://openalex.org/W2485649401","https://openalex.org/W2508214571","https://openalex.org/W2518747826","https://openalex.org/W2554740475","https://openalex.org/W2555226278","https://openalex.org/W2611504779","https://openalex.org/W2795455346","https://openalex.org/W2799312938","https://openalex.org/W2804083274","https://openalex.org/W2804257223","https://openalex.org/W2810175432","https://openalex.org/W2845601613","https://openalex.org/W2884126215","https://openalex.org/W2891906292","https://openalex.org/W2894329930","https://openalex.org/W2896541023","https://openalex.org/W2900678737","https://openalex.org/W2907649002","https://openalex.org/W2909477364","https://openalex.org/W2915823245","https://openalex.org/W2944840932","https://openalex.org/W2950793644","https://openalex.org/W2970160838","https://openalex.org/W2971067538","https://openalex.org/W2977961280","https://openalex.org/W2982418507","https://openalex.org/W2985784301","https://openalex.org/W2991106430","https://openalex.org/W2998467274","https://openalex.org/W2998847910","https://openalex.org/W2999130535","https://openalex.org/W3024261138","https://openalex.org/W3029220716","https://openalex.org/W3033380947","https://openalex.org/W3080493459","https://openalex.org/W3092001828","https://openalex.org/W3106696187","https://openalex.org/W3108232640","https://openalex.org/W3108934829","https://openalex.org/W3112391596","https://openalex.org/W3119825929","https://openalex.org/W3120496591","https://openalex.org/W3126512625","https://openalex.org/W3133954608","https://openalex.org/W3134516572","https://openalex.org/W3149977270","https://openalex.org/W3154641364","https://openalex.org/W3155861482","https://openalex.org/W3159052154","https://openalex.org/W3159995035","https://openalex.org/W3164799781","https://openalex.org/W3165766592","https://openalex.org/W3176288756","https://openalex.org/W3177433188","https://openalex.org/W3190631166","https://openalex.org/W3198853168","https://openalex.org/W3199223754","https://openalex.org/W3202239352","https://openalex.org/W3203834151","https://openalex.org/W3213888013","https://openalex.org/W4213245602","https://openalex.org/W4225095638","https://openalex.org/W4229011537","https://openalex.org/W4254687493","https://openalex.org/W4282939243","https://openalex.org/W4307441073","https://openalex.org/W4312181028","https://openalex.org/W4376610991","https://openalex.org/W4376648498"],"related_works":["https://openalex.org/W4402054171","https://openalex.org/W4402232147","https://openalex.org/W2045611938","https://openalex.org/W2896631314","https://openalex.org/W2013431910","https://openalex.org/W2751714201","https://openalex.org/W66742448","https://openalex.org/W2988683343","https://openalex.org/W2035227838","https://openalex.org/W4414151924"],"abstract_inverted_index":{"Caloric":[0],"restriction":[1,51,71],"and":[2,8,13,29,34,46,52,76,93,106,114,127,151],"intermittent":[3],"fasting":[4,53,68],"prolong":[5],"the":[6,44,98,104,112,130,136],"lifespan":[7],"healthspan":[9],"of":[10,32,49,67,83,117,129],"model":[11],"organisms":[12],"improve":[14],"human":[15,77,94],"health.":[16],"The":[17],"natural":[18],"polyamine":[19,56,99],"spermidine":[20,61,85,120],"has":[21],"been":[22],"similarly":[23],"linked":[24],"to":[25],"autophagy":[26,89,125,149],"enhancement,":[27],"geroprotection":[28],"reduced":[30,87],"incidence":[31],"cardiovascular":[33],"neurodegenerative":[35],"diseases":[36],"across":[37],"species":[38],"borders.":[39],"Here,":[40],"we":[41],"asked":[42],"whether":[43],"cellular":[45],"physiological":[47],"consequences":[48,116],"caloric":[50,70],"depend":[54],"on":[55],"metabolism.":[57],"We":[58],"report":[59],"that":[60],"levels":[62],"increased":[63],"upon":[64],"distinct":[65],"regimens":[66],"or":[69,80],"in":[72,90,101],"yeast,":[73,91],"flies,":[74],"mice":[75],"volunteers.":[78],"Genetic":[79],"pharmacological":[81],"blockade":[82],"endogenous":[84],"synthesis":[86],"fasting-induced":[88],"nematodes":[92],"cells.":[95],"Furthermore,":[96],"perturbing":[97],"pathway":[100],"vivo":[102],"abrogated":[103],"lifespan-":[105],"healthspan-extending":[107],"effects,":[108],"as":[109,111,140],"well":[110],"cardioprotective":[113],"anti-arthritic":[115],"fasting.":[118],"Mechanistically,":[119],"mediated":[121],"these":[122],"effects":[123],"via":[124],"induction":[126],"hypusination":[128],"translation":[131],"regulator":[132],"eIF5A.":[133],"In":[134],"summary,":[135],"polyamine-hypusination":[137],"axis":[138],"emerges":[139],"a":[141],"phylogenetically":[142],"conserved":[143],"metabolic":[144],"control":[145],"hub":[146],"for":[147],"fasting-mediated":[148],"enhancement":[150],"longevity.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":95},{"year":2025,"cited_by_count":74},{"year":2024,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-08-09T00:00:00"}
