{"id":"https://openalex.org/W4401413633","doi":"https://doi.org/10.1016/j.yebeh.2024.109949","title":"Trends in prescription of anti-seizure medications in Japan between 2018 and 2021: A retrospective study using the National Database Open Data Japan","display_name":"Trends in prescription of anti-seizure medications in Japan between 2018 and 2021: A retrospective study using the National Database Open Data Japan","publication_year":2024,"publication_date":"2024-08-08","ids":{"openalex":"https://openalex.org/W4401413633","doi":"https://doi.org/10.1016/j.yebeh.2024.109949","pmid":"https://pubmed.ncbi.nlm.nih.gov/39121754"},"language":"en","primary_location":{"id":"doi:10.1016/j.yebeh.2024.109949","doi":"https://doi.org/10.1016/j.yebeh.2024.109949","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yebeh.2024.109949","pdf_url":null,"source":{"id":"https://openalex.org/S109517664","display_name":"Epilepsy & Behavior","issn_l":"1525-5050","issn":["1525-5050","1525-5069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy & Behavior","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046705146","display_name":"Hiroyuki Ura","orcid":"https://orcid.org/0000-0003-3869-4370","observed_orcids":["https://orcid.org/0000-0003-3869-4370"]},"institutions":[{"id":"https://openalex.org/I4210141149","display_name":"Shonan University of Medical Sciences","ror":"https://ror.org/03jqeq923","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210141149"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiroyuki Ura","raw_affiliation_strings":["Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan; Department of Pharmacy Services, Shiomidai Hospital, Yokohama, Japan. Electronic address: urahiroyuki@gmail.com"],"raw_orcid":"https://orcid.org/0000-0003-3869-4370","affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan; Department of Pharmacy Services, Shiomidai Hospital, Yokohama, Japan. Electronic address: urahiroyuki@gmail.com","institution_ids":["https://openalex.org/I4210141149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114205016","display_name":"Noriko Matsuoka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093346","display_name":"Nippon Medical School Musashi Kosugi Hospital","ror":"https://ror.org/00h5ck659","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210093346"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriko Matsuoka","raw_affiliation_strings":["Department of Pharmacy Services, Nippon Medical School Musashi Kosugi Hospital, Kawasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Nippon Medical School Musashi Kosugi Hospital, Kawasaki, Japan","institution_ids":["https://openalex.org/I4210093346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077702002","display_name":"Kiyoshi Kubota","orcid":"https://orcid.org/0000-0001-6092-8685","observed_orcids":["https://orcid.org/0000-0001-6092-8685"]},"institutions":[{"id":"https://openalex.org/I4210141149","display_name":"Shonan University of Medical Sciences","ror":"https://ror.org/03jqeq923","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210141149"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyoshi Kubota","raw_affiliation_strings":["Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan","institution_ids":["https://openalex.org/I4210141149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000364938","display_name":"Kiyomi Sadamoto","orcid":"https://orcid.org/0000-0001-7670-8687","observed_orcids":["https://orcid.org/0000-0001-7670-8687"]},"institutions":[{"id":"https://openalex.org/I4210141149","display_name":"Shonan University of Medical Sciences","ror":"https://ror.org/03jqeq923","country_code":"JP","type":"education","lineage":["https://openalex.org/I4210141149"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyomi Sadamoto","raw_affiliation_strings":["Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, Shonan University of Medical Science, Yokohama, Japan","institution_ids":["https://openalex.org/I4210141149"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046705146"],"corresponding_institution_ids":["https://openalex.org/I4210141149"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":2.1323,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.86661504,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"159","issue":null,"first_page":"109949","last_page":"109949"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.953000009059906},{"id":"https://openalex.org/keywords/prescribing-trends","display_name":"prescribing trends","score":0.8799999952316284},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.7059999704360962},{"id":"https://openalex.org/keywords/levetiracetam","display_name":"levetiracetam","score":0.8450000286102295},{"id":"https://openalex.org/keywords/lamotrigine","display_name":"lamotrigine","score":1.0},{"id":"https://openalex.org/keywords/valproic-acid","display_name":"valproic acid","score":0.9950000047683716},{"id":"https://openalex.org/keywords/phenytoin","display_name":"phenytoin","score":0.9890000224113464},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8870000243186951},{"id":"https://openalex.org/keywords/women-of-reproductive-age","display_name":"women of reproductive age","score":0.9950000047683716},{"id":"https://openalex.org/keywords/sex-differences-in-prescribing","display_name":"sex differences in prescribing","score":0.843999981880188},{"id":"https://openalex.org/keywords/pediatric-epilepsy","display_name":"pediatric epilepsy","score":0.5019999742507935},{"id":"https://openalex.org/keywords/generic-drug-use","display_name":"generic drug use","score":0.6549999713897705},{"id":"https://openalex.org/keywords/japan","display_name":"Japan","score":0.3070000112056732}],"concepts":[{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.7473701238632202},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6432793736457825},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5275076627731323},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.519499659538269},{"id":"https://openalex.org/C3018723762","wikidata":"https://www.wikidata.org/wiki/Q3071343","display_name":"National database","level":2,"score":0.45590347051620483},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.4257379174232483},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.394178181886673},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3286142349243164},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.14220449328422546},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1310890018939972},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.07286164164543152},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.06311231851577759}],"mesh":[{"descriptor_ui":"D000077213","descriptor_name":"Lamotrigine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000077287","descriptor_name":"Levetiracetam","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011307","descriptor_name":"Drug Prescriptions","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014635","descriptor_name":"Valproic Acid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.yebeh.2024.109949","doi":"https://doi.org/10.1016/j.yebeh.2024.109949","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yebeh.2024.109949","pdf_url":null,"source":{"id":"https://openalex.org/S109517664","display_name":"Epilepsy & Behavior","issn_l":"1525-5050","issn":["1525-5050","1525-5069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy & Behavior","raw_type":"journal-article"},{"id":"pmid:39121754","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39121754","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy & behavior : E&B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1963845179","https://openalex.org/W1969159860","https://openalex.org/W1969611215","https://openalex.org/W1975807583","https://openalex.org/W1983142641","https://openalex.org/W1992717675","https://openalex.org/W1999926752","https://openalex.org/W2014297915","https://openalex.org/W2053816089","https://openalex.org/W2058176042","https://openalex.org/W2062565331","https://openalex.org/W2065151935","https://openalex.org/W2070728679","https://openalex.org/W2070915719","https://openalex.org/W2082629538","https://openalex.org/W2127345802","https://openalex.org/W2129298507","https://openalex.org/W2138521331","https://openalex.org/W2146629358","https://openalex.org/W2163842154","https://openalex.org/W2306843755","https://openalex.org/W2399360087","https://openalex.org/W2580764146","https://openalex.org/W2619774390","https://openalex.org/W2726071308","https://openalex.org/W2790292583","https://openalex.org/W2795125461","https://openalex.org/W2908603053","https://openalex.org/W2922528234","https://openalex.org/W2932379030","https://openalex.org/W2987803466","https://openalex.org/W3005756617","https://openalex.org/W3043248661","https://openalex.org/W3099802627","https://openalex.org/W3110806716","https://openalex.org/W3130456059","https://openalex.org/W3138684152","https://openalex.org/W3203880789","https://openalex.org/W4214901238","https://openalex.org/W4220843692","https://openalex.org/W4221115273","https://openalex.org/W4224038331","https://openalex.org/W4225948273","https://openalex.org/W4297236004","https://openalex.org/W4322389355","https://openalex.org/W4361248023","https://openalex.org/W6648327462"],"related_works":["https://openalex.org/W4287576240","https://openalex.org/W3194575546","https://openalex.org/W4220819943","https://openalex.org/W3165809038","https://openalex.org/W4220995569","https://openalex.org/W4224038331","https://openalex.org/W3082130711","https://openalex.org/W4389150743","https://openalex.org/W4317535205","https://openalex.org/W4280607422"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-08-09T00:00:00"}