{"id":"https://openalex.org/W4401237451","doi":"https://doi.org/10.3724/sp.j.1123.2023.10013","title":"Simultaneous determination of 10 quaternary ammonium salt bactericides in oral care products by high performance liquid chromatography-evaporative light-scattering detection","display_name":"Simultaneous determination of 10 quaternary ammonium salt bactericides in oral care products by high performance liquid chromatography-evaporative light-scattering detection","publication_year":2024,"publication_date":"2024-08-01","ids":{"openalex":"https://openalex.org/W4401237451","doi":"https://doi.org/10.3724/sp.j.1123.2023.10013","pmid":"https://pubmed.ncbi.nlm.nih.gov/39086247","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11292477"},"language":"zh","primary_location":{"id":"doi:10.3724/sp.j.1123.2023.10013","doi":"https://doi.org/10.3724/sp.j.1123.2023.10013","is_oa":false,"landing_page_url":"http://dx.doi.org/10.3724/sp.j.1123.2023.10013","pdf_url":null,"source":{"id":"https://openalex.org/S4210240353","display_name":"Chinese Journal of Chromatography","issn_l":"1000-8713","issn":["1000-8713","1872-2059"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319982","host_organization_name":"Science Press","host_organization_lineage":["https://openalex.org/P4310319982"],"host_organization_lineage_names":["Science Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Journal of Chromatography","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11292477/pdf/cjc-42-08-783.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101438216","display_name":"Juan Tang","orcid":"https://orcid.org/0000-0001-9801-4774","observed_orcids":["https://orcid.org/0000-0001-9801-4774"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juan TANG","raw_affiliation_strings":["Industrial Products Testing Center, Nanjing Customs, Nanjing 210019, China","Nanjing Jinjian Inspection Co., Ltd., Nanjing 210019, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Products Testing Center, Nanjing Customs, Nanjing 210019, China","institution_ids":[]},{"raw_affiliation_string":"Nanjing Jinjian Inspection Co., Ltd., Nanjing 210019, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110410512","display_name":"Youchao Ding","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Youchao DING","raw_affiliation_strings":["Industrial Products Testing Center, Nanjing Customs, Nanjing 210019, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Industrial Products Testing Center, Nanjing Customs, Nanjing 210019, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081458216","display_name":"Xiao-Qing Fei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaoqing FEI","raw_affiliation_strings":["Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113317227","display_name":"Bin Wu","orcid":"https://orcid.org/0000-0002-6323-5734","observed_orcids":["https://orcid.org/0000-0002-6323-5734"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bin WU","raw_affiliation_strings":["Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035721882","display_name":"Zhijuan Qian","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhijuan QIAN","raw_affiliation_strings":["Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008041408","display_name":"Shan-Dan Chen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shandan CHEN","raw_affiliation_strings":["Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026606042","display_name":"Bai Li","orcid":"https://orcid.org/0000-0002-3047-5061","observed_orcids":["https://orcid.org/0000-0002-3047-5061"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bai LI","raw_affiliation_strings":["Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Light Industrial Products and Children's Products Inspection Center, Nanjing Customs, Yangzhou 225009, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5113317227"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"8","first_page":"783","last_page":"791"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.4350999891757965,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.4350999891757965,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.21170000731945038,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.16110000014305115,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-hygiene-products","display_name":"oral care products","score":0.9639999866485596},{"id":"https://openalex.org/keywords/simultaneous-determination","display_name":"simultaneous determination","score":0.847000002861023},{"id":"https://openalex.org/keywords/hplc-elsd","display_name":"HPLC-ELSD","score":0.9089999794960022},{"id":"https://openalex.org/keywords/sample-dehydration","display_name":"sample dehydration","score":0.7620000243186951},{"id":"https://openalex.org/keywords/anhydrous-sodium-sulfate","display_name":"anhydrous sodium sulfate","score":0.8930000066757202},{"id":"https://openalex.org/keywords/ultrasound-assisted-extraction","display_name":"ultrasound-assisted extraction","score":0.8510000109672546},{"id":"https://openalex.org/keywords/ethanol-extraction","display_name":"ethanol extraction","score":0.8640000224113464},{"id":"https://openalex.org/keywords/benzethonium-chloride","display_name":"benzethonium chloride","score":0.7070000171661377},{"id":"https://openalex.org/keywords/dodecyltrimethylammonium-chloride","display_name":"dodecyltrimethylammonium chloride","score":0.9279999732971191},{"id":"https://openalex.org/keywords/contact-dermatitis","display_name":"contact dermatitis","score":0.5339999794960022},{"id":"https://openalex.org/keywords/scalding","display_name":"scalding","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9039480090141296},{"id":"https://openalex.org/C2779870022","wikidata":"https://www.wikidata.org/wiki/Q190901","display_name":"Ammonium","level":2,"score":0.7659199237823486},{"id":"https://openalex.org/C2776371256","wikidata":"https://www.wikidata.org/wiki/Q12370","display_name":"Salt (chemistry)","level":2,"score":0.7495347261428833},{"id":"https://openalex.org/C2779660836","wikidata":"https://www.wikidata.org/wiki/Q188543","display_name":"Ammonium chloride","level":2,"score":0.6470118761062622},{"id":"https://openalex.org/C110084920","wikidata":"https://www.wikidata.org/wiki/Q381624","display_name":"Chromatography detector","level":3,"score":0.6356834769248962},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6341179609298706},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5481080412864685},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.5137168169021606},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1867065727710724}],"mesh":[{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012542","descriptor_name":"Scattering, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3724/sp.j.1123.2023.10013","doi":"https://doi.org/10.3724/sp.j.1123.2023.10013","is_oa":false,"landing_page_url":"http://dx.doi.org/10.3724/sp.j.1123.2023.10013","pdf_url":null,"source":{"id":"https://openalex.org/S4210240353","display_name":"Chinese Journal of Chromatography","issn_l":"1000-8713","issn":["1000-8713","1872-2059"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319982","host_organization_name":"Science Press","host_organization_lineage":["https://openalex.org/P4310319982"],"host_organization_lineage_names":["Science Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Journal of Chromatography","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11292477","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11292477","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11292477/pdf/cjc-42-08-783.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Se Pu","raw_type":"Text"},{"id":"pmid:39086247","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39086247","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Se pu = Chinese journal of chromatography","raw_type":"English Abstract"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11292477","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11292477","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11292477/pdf/cjc-42-08-783.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Se Pu","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401237451.pdf","grobid_xml":"https://content.openalex.org/works/W4401237451.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W231976150","https://openalex.org/W2027724952","https://openalex.org/W2062118746","https://openalex.org/W2063916033","https://openalex.org/W2208325996","https://openalex.org/W2463284852","https://openalex.org/W2749910900","https://openalex.org/W2793763518","https://openalex.org/W3177969961","https://openalex.org/W3189779348","https://openalex.org/W4210990510","https://openalex.org/W4247967953","https://openalex.org/W4311173383","https://openalex.org/W4322757411","https://openalex.org/W4399321757"],"related_works":["https://openalex.org/W4387229444","https://openalex.org/W1973344590","https://openalex.org/W6936546646","https://openalex.org/W4402567659","https://openalex.org/W2349400069","https://openalex.org/W3111184012","https://openalex.org/W2374838331","https://openalex.org/W2070194197","https://openalex.org/W2392083087","https://openalex.org/W3159056159"],"abstract_inverted_index":{"Quaternary":[0],"ammonium":[1,30,47,77,107,123,325],"salt":[2,31,48,78,108],"bactericides":[3,6,32,49,79,109,141],"are":[4,50,169],"broad-spectrum":[5],"often":[7],"used":[8,154,248,364,515],"in":[9,110,172,176,249,419,433,457,471,537,566],"oral":[10,111,519,568,586],"care":[11,112,520,569,587],"products":[12],"because":[13],"of":[14,28,60,74,105,139,186,216,224,254,276,300,389,396,404,422,436,445,460,534,547,561,585],"their":[15],"high":[16,92,528],"antibacterial":[17],"efficacy,":[18],"strong":[19],"penetration,":[20],"and":[21,39,67,135,159,189,213,229,237,259,280,298,331,380,400,412,454,463,480,487,490,499,524,550,582],"low":[22],"toxicity.":[23],"However,":[24],"the":[25,58,71,102,184,191,214,222,225,244,262,269,277,301,308,405,420,426,434,458,488,500,532,552,558,562,580],"excessive":[26],"use":[27],"quaternary":[29,46,76,106],"may":[33],"cause":[34],"contact":[35],"dermatitis,":[36],"scalding":[37],"poisoning,":[38],"even":[40],"death.":[41],"Existing":[42],"methods":[43,204],"to":[44,52,57,156,516],"determine":[45],"unable":[51],"meet":[53],"current":[54],"requirements":[55],"owing":[56,155],"lack":[59],"determination":[61,104],"components.":[62],"Therefore,":[63],"establishing":[64],"a":[65,85,148,387,577],"simple":[66],"accurate":[68],"method":[69,86,362,513,554],"for":[70,101,290,365,557,579],"simultaneous":[72,103],"detection":[73,97,397,529],"more":[75],"is":[80,555],"necessary.":[81,198],"In":[82,199,439],"this":[83,200,250],"study,":[84,201],"that":[87],"couples":[88],"sample":[89,187,195,303,540],"pretreatment":[90,188],"with":[91,304,322],"performance":[93],"liquid":[94,302],"chromatography-evaporative":[95],"light-scattering":[96,151],"(HPLC-ELSD)":[98],"was":[99,153,197,211,218,239,243,363,514],"developed":[100,512,553],"products,":[113],"including":[114],"dodecyltrimethylammonium":[115],"chloride,":[116,118,120,124,126,128,130,132,134],"dodecyldimethylbenzylammonium":[117],"benzethonium":[119],"tetradecyl":[121],"trimethyl":[122],"tetradecyldimethylbenzylammonium":[125],"N-hexadecyltrimethylammonium":[127],"benzyldimethylhexadecylammonium":[129],"trimethylstearylammonium":[131],"stearyldimethylbenzylammonium":[133,525,535],"docosyltrimethylammonium":[136,413],"chloride.":[137],"Some":[138],"these":[140,179],"do":[142],"not":[143,507],"absorb":[144],"ultraviolet":[145],"light,":[146],"so":[147],"universal":[149],"evaporative":[150],"detector":[152],"testing":[157],"cost":[158],"stability":[160],"concerns.":[161],"The":[162,252,337,368,394,452,494,511,571],"paste":[163,279],"samples":[164,282,309],"contained":[165],"thickening":[166],"agents,":[167],"which":[168],"highly":[170],"soluble":[171],"water":[173],"but":[174],"insoluble":[175],"organic":[177],"solvents;":[178],"agents":[180],"can":[181,574],"seriously":[182],"affect":[183],"results":[185],"damage":[190],"chromatographic":[192],"column.":[193],"Hence,":[194],"dehydration":[196,203],"four":[202],"were":[205,235,265,272,310,341,371,383,408,450,456,469,492,497],"compared.":[206],"Anhydrous":[207],"sodium":[208],"sulfate":[209],"(Na2SO4)":[210],"selected,":[212],"amount":[215,533],"Na2SO4":[217],"optimized.":[219],"Based":[220],"on":[221,261,312],"solubility":[223],"10":[226,369,406,563],"target":[227],"compounds":[228,370,428,565],"extraction":[230,233,242,246,263,275],"efficiency,":[231],"three":[232,485],"solvents":[234],"compared,":[236],"ethanol":[238,284],"selected.":[240],"Ultrasonic":[241],"primary":[245],"process":[247],"study.":[251],"effects":[253],"different":[255],"ultrasonication":[256],"times,":[257],"temperatures,":[258],"powers":[260],"recoveries":[264,489,496],"also":[266],"investigated.":[267],"Ultimately,":[268],"optimized":[270],"conditions":[271],"as":[273,334,342,475,576],"follows:":[274,343],"dehydrated":[278],"powder":[281,482],"using":[283],"at":[285,484],"room":[286],"temperature":[287],"(25":[288],"\u2103)":[289],"20":[291],"min":[292],"under":[293],"100":[294],"W":[295],"ultrasound":[296],"power,":[297],"dilution":[299],"ethanol.":[305],"After":[306],"extraction,":[307],"separated":[311],"an":[313],"Acclaim":[314],"Surfactant":[315],"column":[316],"(150":[317],"mm\u00d74.6":[318],"mm,":[319],"5":[320],"\u03bcm)":[321],"50":[323],"mmol/L":[324],"acetate":[326],"aqueous":[327],"solution":[328],"(pH=5.5)":[329],"(A)":[330],"acetonitrile":[332],"(B)":[333],"mobile":[335],"phases.":[336],"gradient":[338],"elution":[339],"program":[340],"0-5.0":[344],"min,":[345,348,351,354,357],"75%A-35%A,":[346],"5.0-15.0":[347],"35%A-20%A,":[349],"15.0-20.0":[350],"20%A,":[352],"20.0-21.0":[353],"20%A-75%A,":[355],"21.0-25.0":[356],"75%A.":[358],"An":[359],"external":[360],"standard":[361,391,503],"quantitative":[366,559],"determination.":[367],"analyzed":[372],"within":[373],"25":[374],"min.":[375],"Linear":[376],"equations,":[377],"correlation":[378,442],"coefficients,":[379],"linear":[381,417,431],"ranges":[382],"obtained":[384],"by":[385],"analyzing":[386],"series":[388],"mixed":[390],"working":[392],"solutions.":[393],"limits":[395],"(LODs,":[398],"S/N=3)":[399],"quantification":[401],"(LOQs,":[402],"S/N=10)":[403],"components":[407],"determined.":[409],"Stearyldimethylbenzylammonium":[410],"chloride":[411,414,523,526,536],"showed":[415],"good":[416,430,548],"relationships":[418,432],"range":[421,435,459],"10-200":[423],"mg/L,":[424,465],"while":[425],"other":[427],"demonstrated":[429],"5-100":[437],"mg/L.":[438],"all":[440],"cases,":[441],"coefficients":[443],"(R2)":[444],"no":[446],"less":[447],"than":[448],"0.9992":[449],"obtained.":[451],"LODs":[453],"LOQs":[455],"1.42-3.31":[461],"mg/L":[462],"4.25-9.94":[464],"respectively.":[466],"Ten":[467],"analytes":[468],"spiked":[470],"blank":[472],"matrices,":[473],"such":[474],"toothpaste":[476,539],"(paste),":[477],"mouthwash":[478],"(liquid),":[479],"dentifrice":[481],"(powder)":[483],"levels,":[486],"precisions":[491],"calculated.":[493],"average":[495],"87.9%-103.1%,":[498],"corresponding":[501],"relative":[502],"deviations":[504],"(RSDs)":[505],"did":[506],"exceed":[508],"5.5%":[509],"(n=6).":[510],"detect":[517],"109":[518],"products.":[521,570,588],"Benzyldimethylhexadecylammonium":[522],"revealed":[527],"rates.":[530],"Moreover,":[531],"one":[538],"exceeded":[541],"regulatory":[542],"requirements.":[543],"Given":[544],"its":[545],"advantages":[546],"precision":[549],"accuracy,":[551],"suitable":[556],"analysis":[560],"aforementioned":[564],"typical":[567],"study":[572],"findings":[573],"serve":[575],"reference":[578],"quality":[581],"safety":[583],"monitoring":[584]},"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2024-08-02T00:00:00"}