{"id":"https://openalex.org/W4401199738","doi":"https://doi.org/10.2147/ppa.s463354","title":"Preference for a Novel Oral Alternative to Parenterally Administered Medications","display_name":"Preference for a Novel Oral Alternative to Parenterally Administered Medications","publication_year":2024,"publication_date":"2024-07-01","ids":{"openalex":"https://openalex.org/W4401199738","doi":"https://doi.org/10.2147/ppa.s463354","pmid":"https://pubmed.ncbi.nlm.nih.gov/39100431","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11298207"},"language":"en","primary_location":{"id":"doi:10.2147/ppa.s463354","doi":"https://doi.org/10.2147/ppa.s463354","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ppa.s463354","pdf_url":null,"source":{"id":"https://openalex.org/S66639021","display_name":"Patient Preference and Adherence","issn_l":"1177-889X","issn":["1177-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Patient Preference and Adherence","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2147/ppa.s463354","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048799109","display_name":"Joshua T. Myers","orcid":"https://orcid.org/0009-0002-1467-6282","observed_orcids":["https://orcid.org/0009-0002-1467-6282"]},"institutions":[{"id":"https://openalex.org/I4210163868","display_name":"Rani Therapeutics (United States)","ror":"https://ror.org/05ekwg650","country_code":"US","type":"company","lineage":["https://openalex.org/I4210163868"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joshua Myers","raw_affiliation_strings":["Rani Therapeutics, San Jose, CA, USA"],"raw_orcid":"https://orcid.org/0009-0002-1467-6282","affiliations":[{"raw_affiliation_string":"Rani Therapeutics, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210163868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103848717","display_name":"Jacques Van Dam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163868","display_name":"Rani Therapeutics (United States)","ror":"https://ror.org/05ekwg650","country_code":"US","type":"company","lineage":["https://openalex.org/I4210163868"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jacques Van Dam","raw_affiliation_strings":["Rani Therapeutics, San Jose, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rani Therapeutics, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210163868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104085323","display_name":"Mir Imran","orcid":"https://orcid.org/0009-0009-8150-3825","observed_orcids":["https://orcid.org/0009-0009-8150-3825"]},"institutions":[{"id":"https://openalex.org/I4210163868","display_name":"Rani Therapeutics (United States)","ror":"https://ror.org/05ekwg650","country_code":"US","type":"company","lineage":["https://openalex.org/I4210163868"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mir Imran","raw_affiliation_strings":["Rani Therapeutics, San Jose, CA, USA"],"raw_orcid":"https://orcid.org/0009-0009-8150-3825","affiliations":[{"raw_affiliation_string":"Rani Therapeutics, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210163868"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112471908","display_name":"Mir A. Hashim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163868","display_name":"Rani Therapeutics (United States)","ror":"https://ror.org/05ekwg650","country_code":"US","type":"company","lineage":["https://openalex.org/I4210163868"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mir Hashim","raw_affiliation_strings":["Rani Therapeutics, San Jose, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rani Therapeutics, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210163868"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043772939","display_name":"Arvinder K. Dhalla","orcid":"https://orcid.org/0000-0002-1415-7928","observed_orcids":["https://orcid.org/0000-0002-1415-7928"]},"institutions":[{"id":"https://openalex.org/I4210163868","display_name":"Rani Therapeutics (United States)","ror":"https://ror.org/05ekwg650","country_code":"US","type":"company","lineage":["https://openalex.org/I4210163868"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arvinder Dhalla","raw_affiliation_strings":["Rani Therapeutics, San Jose, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rani Therapeutics, San Jose, CA, USA","institution_ids":["https://openalex.org/I4210163868"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043772939","https://openalex.org/A5048799109","https://openalex.org/A5103848717","https://openalex.org/A5104085323","https://openalex.org/A5112471908"],"corresponding_institution_ids":["https://openalex.org/I4210163868"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":5.8683,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.97420902,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"Volume 18","issue":null,"first_page":"1547","last_page":"1562"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.48579999804496765,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.48579999804496765,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.22529999911785126,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11620","display_name":"Medication Adherence and Compliance","score":0.02290000021457672,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.6480000019073486},{"id":"https://openalex.org/keywords/parenteral-administration","display_name":"parenteral administration","score":0.6480000019073486},{"id":"https://openalex.org/keywords/patient-preferences","display_name":"patient preferences","score":0.6060000061988831},{"id":"https://openalex.org/keywords/biologic-drugs","display_name":"biologic drugs","score":0.5180000066757202},{"id":"https://openalex.org/keywords/dosing-frequency","display_name":"dosing frequency","score":0.7369999885559082},{"id":"https://openalex.org/keywords/patient-adherence","display_name":"patient adherence","score":0.4749999940395355},{"id":"https://openalex.org/keywords/physician-preferences","display_name":"physician preferences","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9565643668174744},{"id":"https://openalex.org/C81603835","wikidata":"https://www.wikidata.org/wiki/Q3457430","display_name":"Pill","level":2,"score":0.7408974170684814},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.6849761009216309},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4406949281692505},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.4361491799354553},{"id":"https://openalex.org/C3019315460","wikidata":"https://www.wikidata.org/wiki/Q285166","display_name":"Oral route","level":2,"score":0.4200614392757416},{"id":"https://openalex.org/C2781249084","wikidata":"https://www.wikidata.org/wiki/Q908656","display_name":"Preference","level":2,"score":0.4183427393436432},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.33692991733551025},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3030737042427063},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2319229245185852},{"id":"https://openalex.org/C175444787","wikidata":"https://www.wikidata.org/wiki/Q39072","display_name":"Microeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/ppa.s463354","doi":"https://doi.org/10.2147/ppa.s463354","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ppa.s463354","pdf_url":null,"source":{"id":"https://openalex.org/S66639021","display_name":"Patient Preference and Adherence","issn_l":"1177-889X","issn":["1177-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Patient Preference and Adherence","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11298207","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11298207","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11298207/pdf/ppa-18-1547.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Patient Prefer Adherence","raw_type":"Text"},{"id":"pmid:39100431","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39100431","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Patient preference and adherence","raw_type":"Journal Article"},{"id":"pmh:oai:dovepress.com/94648","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/preference-for-a-novel-oral-alternative-to-parenterally-administered-m-peer-reviewed-fulltext-article-PPA","pdf_url":"https://www.dovepress.com/article/download/94648","source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:01d6125c93064099bb5288df912e236b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/01d6125c93064099bb5288df912e236b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Patient Preference and Adherence, Vol Volume 18, Pp 1547-1562 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2147/ppa.s463354","doi":"https://doi.org/10.2147/ppa.s463354","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ppa.s463354","pdf_url":null,"source":{"id":"https://openalex.org/S66639021","display_name":"Patient Preference and Adherence","issn_l":"1177-889X","issn":["1177-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Patient Preference and Adherence","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401199738.pdf","grobid_xml":"https://content.openalex.org/works/W4401199738.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W75919856","https://openalex.org/W1987467697","https://openalex.org/W1991146506","https://openalex.org/W1995634245","https://openalex.org/W1995693115","https://openalex.org/W1996879430","https://openalex.org/W2017716530","https://openalex.org/W2021907443","https://openalex.org/W2026496436","https://openalex.org/W2036387352","https://openalex.org/W2058407858","https://openalex.org/W2066677251","https://openalex.org/W2067732792","https://openalex.org/W2088998005","https://openalex.org/W2113057023","https://openalex.org/W2115977452","https://openalex.org/W2116154858","https://openalex.org/W2127083129","https://openalex.org/W2147325147","https://openalex.org/W2155990793","https://openalex.org/W2156108549","https://openalex.org/W2158350833","https://openalex.org/W2165473026","https://openalex.org/W2181136160","https://openalex.org/W2209332382","https://openalex.org/W2306917199","https://openalex.org/W2412378911","https://openalex.org/W2463562243","https://openalex.org/W2548985910","https://openalex.org/W2596498480","https://openalex.org/W2622210331","https://openalex.org/W2776016310","https://openalex.org/W2910702365","https://openalex.org/W2963429312","https://openalex.org/W2977374807","https://openalex.org/W2977666074","https://openalex.org/W3039300106","https://openalex.org/W3095909321","https://openalex.org/W3110897709","https://openalex.org/W3127011561","https://openalex.org/W3129419639","https://openalex.org/W3131844831","https://openalex.org/W3145781730","https://openalex.org/W3157844831","https://openalex.org/W3173128820","https://openalex.org/W3194332938","https://openalex.org/W3195042853","https://openalex.org/W3197317315","https://openalex.org/W4200355173","https://openalex.org/W4206717797","https://openalex.org/W4226408133","https://openalex.org/W4244227182","https://openalex.org/W4284704501","https://openalex.org/W4285802154","https://openalex.org/W4309660134","https://openalex.org/W4312066738","https://openalex.org/W4378516296","https://openalex.org/W4387361095","https://openalex.org/W4387361158","https://openalex.org/W4387380231"],"related_works":["https://openalex.org/W1983511470","https://openalex.org/W2401175782","https://openalex.org/W4321442911","https://openalex.org/W2148417448","https://openalex.org/W7162316374","https://openalex.org/W4396694191","https://openalex.org/W2326576502","https://openalex.org/W2897781055","https://openalex.org/W2109374857","https://openalex.org/W4410339309"],"abstract_inverted_index":{"Background:":[0],"that":[1],"can":[2],"deliver":[3],"a":[4,27,34,73,124,128,204,222],"number":[5],"of":[6,79,123,135,155,185,243],"biotherapeutics":[7],"with":[8,249],"high":[9],"bioavailability;":[10],"eliminating":[11],"the":[12,106,109,121,160,169,177,193,250,255],"need":[13],"for":[14,26,51,64,98,117,176],"injections.":[15],"While":[16],"patients":[17],"in":[18,192],"general":[19],"prefer":[20,221,237],"oral":[21,30,52,65,147,178,238,251],"to":[22,33,46,88,101,143,145,167,202,208,240],"injectable":[23,37,54],"therapies,":[24],"preference":[25,50,63,100,175],"more":[28,200],"frequent":[29,36,197],"regimen":[31,38],"compared":[32,207],"less":[35],"is":[39,257],"unknown.":[40],"Two":[41],"marketing":[42],"surveys":[43],"were":[44,94,165,199],"conducted":[45],"gather":[47],"data":[48,60],"on":[49,61],"versus":[53,180],"therapies.":[55],"A":[56,77],"clinical":[57,110,161,194],"study":[58,195,213],"gathered":[59],"participant":[62],"pills":[66],"vs":[67],"injections":[68,83,116,198,232],"before":[69],"and":[70,126,171,190,233],"after":[71],"swallowing":[72],"Mock-RP":[74,125,170],"capsule.":[75],"Methods:":[76],"total":[78],"1689":[80],"adults":[81],"taking":[82,115,231],"(mean":[84],"duration":[85],"3-7":[86],"years)":[87],"treat":[89],"endocrine":[90],"or":[91,157],"inflammatory":[92],"conditions":[93,119],"anonymously":[95],"surveyed":[96,137],"online":[97],"their":[99,131,150,174,181,226],"administer/prescribe":[102],"medications":[103],"orally":[104],"via":[105],"RP.":[107],"In":[108,159],"study,":[111,162],"150":[112],"participants":[113,164,214],"currently":[114],"chronic":[118],"evaluated":[120],"swallowability":[122],"completed":[127],"questionnaire":[129],"regarding":[130],"preferences.":[132],"Results:":[133],"Majority":[134],"respondents":[136,189],"stated":[138],"they":[139],"would":[140,220],"be":[141],"willing":[142,201],"convert":[144],"an":[146],"alternative":[148],"over":[149,225],"current":[151,182],"parenteral":[152,183,241],"therapy":[153],"regardless":[154],"drug":[156,186],"disease.":[158],"all":[163],"able":[166],"swallow":[168],"91%":[172],"indicated":[173],"route":[179,184],"administration.":[187],"Survey":[188],"those":[191,209],"using":[196],"select":[203],"once-daily":[205,223],"capsule":[206],"injecting":[210],"infrequently.":[211],"Even":[212],"who":[215],"inject":[216],"infrequently":[217],"(\u2265monthly:":[218],"80%)":[219],"pill":[224],"injection":[227],"regimen.":[228],"Conclusion:":[229],"Patients":[230],"prescribing":[234],"physicians":[235],"strongly":[236],"dosing":[239,247],"administration":[242],"biologics":[244],"even":[245],"if":[246],"frequency":[248],"option,":[252],"such":[253],"as":[254],"RP,":[256],"increased.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":24},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-08-01T00:00:00"}
