{"id":"https://openalex.org/W4401145292","doi":"https://doi.org/10.1016/j.spc.2024.07.023","title":"Life cycle assessment of Beefy-9 and Beefy-R serum-free culture media for cell-cultivated beef production","display_name":"Life cycle assessment of Beefy-9 and Beefy-R serum-free culture media for cell-cultivated beef production","publication_year":2024,"publication_date":"2024-07-30","ids":{"openalex":"https://openalex.org/W4401145292","doi":"https://doi.org/10.1016/j.spc.2024.07.023"},"language":"en","primary_location":{"id":"doi:10.1016/j.spc.2024.07.023","doi":"https://doi.org/10.1016/j.spc.2024.07.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.spc.2024.07.023","pdf_url":"https://www.sciencedirect.com/science/article/am/pii/S2352550924002161?via%3Dihub","source":{"id":"https://openalex.org/S2764749963","display_name":"Sustainable Production and Consumption","issn_l":"2352-5509","issn":["2352-5509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Sustainable Production and Consumption","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/am/pii/S2352550924002161?via%3Dihub","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089722025","display_name":"Amin Nikkhah","orcid":"https://orcid.org/0000-0002-3008-2401","observed_orcids":["https://orcid.org/0000-0002-3008-2401"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amin Nikkhah","raw_affiliation_strings":["Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092090371","display_name":"Kirsten R. Trinidad","orcid":"https://orcid.org/0000-0002-0409-7095","observed_orcids":["https://orcid.org/0000-0002-0409-7095"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kirsten Trinidad","raw_affiliation_strings":["Biomedical Engineering Department, Tufts University, Medford, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057871048","display_name":"David Lee Kaplan","orcid":"https://orcid.org/0000-0002-9245-7774","observed_orcids":["https://orcid.org/0000-0002-9245-7774"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David L. Kaplan","raw_affiliation_strings":["Biomedical Engineering Department, Tufts University, Medford, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Tufts University, Medford, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076853338","display_name":"Nicole Tichenor Blackstone","orcid":"https://orcid.org/0000-0001-8343-3650","observed_orcids":["https://orcid.org/0000-0001-8343-3650"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nicole Tichenor Blackstone","raw_affiliation_strings":["Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5076853338"],"corresponding_institution_ids":["https://openalex.org/I121934306"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":{"value":3200,"currency":"USD","value_usd":3200},"fwci":2.4047,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.88197532,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"50","issue":null,"first_page":"168","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11259","display_name":"Agriculture Sustainability and Environmental Impact","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11259","display_name":"Agriculture Sustainability and Environmental Impact","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10435","display_name":"Environmental Impact and Sustainability","score":0.045099999755620956,"subfield":{"id":"https://openalex.org/subfields/2305","display_name":"Environmental Engineering"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12896","display_name":"Sustainable Agricultural Systems Analysis","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/life-cycle-assessment","display_name":"life cycle assessment","score":0.8840000033378601},{"id":"https://openalex.org/keywords/serum-free-medium","display_name":"serum-free medium","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cultured-meat","display_name":"cultured meat","score":0.6930000185966492},{"id":"https://openalex.org/keywords/environmental-impact","display_name":"environmental impact","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2778348673","wikidata":"https://www.wikidata.org/wiki/Q739302","display_name":"Production (economics)","level":2,"score":0.6022639870643616},{"id":"https://openalex.org/C2778706760","wikidata":"https://www.wikidata.org/wiki/Q581950","display_name":"Life-cycle assessment","level":3,"score":0.4445280432701111},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.3491228222846985},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.32801902294158936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3255190849304199},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.20013216137886047},{"id":"https://openalex.org/C175444787","wikidata":"https://www.wikidata.org/wiki/Q39072","display_name":"Microeconomics","level":1,"score":0.08671808242797852}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.spc.2024.07.023","doi":"https://doi.org/10.1016/j.spc.2024.07.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.spc.2024.07.023","pdf_url":"https://www.sciencedirect.com/science/article/am/pii/S2352550924002161?via%3Dihub","source":{"id":"https://openalex.org/S2764749963","display_name":"Sustainable Production and Consumption","issn_l":"2352-5509","issn":["2352-5509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Sustainable Production and Consumption","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.spc.2024.07.023","doi":"https://doi.org/10.1016/j.spc.2024.07.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.spc.2024.07.023","pdf_url":"https://www.sciencedirect.com/science/article/am/pii/S2352550924002161?via%3Dihub","source":{"id":"https://openalex.org/S2764749963","display_name":"Sustainable Production and Consumption","issn_l":"2352-5509","issn":["2352-5509"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-2","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Sustainable Production and Consumption","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12","score":0.8799999952316284},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.5666999816894531}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6600000262260437}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6278118770","display_name":null,"funder_award_id":"2021-699012-35978","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G7184914837","display_name":null,"funder_award_id":"2021-699012-35978","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401145292.pdf","grobid_xml":"https://content.openalex.org/works/W4401145292.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W63660586","https://openalex.org/W1941150540","https://openalex.org/W1999023852","https://openalex.org/W2017526894","https://openalex.org/W2091300510","https://openalex.org/W2220742959","https://openalex.org/W2332797918","https://openalex.org/W2549747412","https://openalex.org/W2744784871","https://openalex.org/W2787389823","https://openalex.org/W2801703802","https://openalex.org/W2804395012","https://openalex.org/W2899557174","https://openalex.org/W2966007063","https://openalex.org/W2997505966","https://openalex.org/W3001887149","https://openalex.org/W3111484275","https://openalex.org/W3170462194","https://openalex.org/W4206044308","https://openalex.org/W4206980534","https://openalex.org/W4214512540","https://openalex.org/W4281769629","https://openalex.org/W4283383344","https://openalex.org/W4293066172","https://openalex.org/W4297537041","https://openalex.org/W4309606320","https://openalex.org/W4311153904","https://openalex.org/W4311519780","https://openalex.org/W4315786930","https://openalex.org/W4327923979","https://openalex.org/W4383665132","https://openalex.org/W4386986614","https://openalex.org/W4391252898","https://openalex.org/W4395663753","https://openalex.org/W4399374829"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189","https://openalex.org/W2013243191","https://openalex.org/W1971568933"],"abstract_inverted_index":{"The":[0],"sustainable":[1,240],"production":[2,136],"of":[3,9,33,130,172,184,195,203,222],"cell-cultivated":[4],"meat":[5,35],"requires":[6],"the":[7,17,30,127,179,201],"use":[8],"environmentally":[10],"friendly":[11],"nutrients.":[12],"Culture":[13],"media,":[14,72],"which":[15],"provides":[16],"necessary":[18],"nutrients":[19],"for":[20,63,140,214,242,259],"cell":[21,59],"proliferation":[22],"and":[23,49,53,81,85,90,132,137,147,208,219,226,263],"differentiation":[24],"is":[25,41,253],"a":[26,238],"major":[27],"contributor":[28],"to":[29,44,95,125,167,255],"environmental":[31,109,128,164],"impacts":[32,110,165],"cultivated":[34],"production.":[36,197],"Fetal":[37],"bovine":[38,64,246],"serum":[39],"(FBS)":[40],"problematic":[42],"due":[43],"animal":[45],"sourcing,":[46],"ethical":[47],"concerns,":[48],"high":[50],"cost.":[51],"Beefy-R":[52,86,133,160,185],"Beefy-9":[54,84,131,168,196],"are":[55],"experimentally":[56],"validated,":[57],"serum-free":[58,248],"culture":[60,101,134,267],"media":[61,102,135,249],"designed":[62],"myoblast":[65,247],"culture.":[66],"While":[67,99],"both":[68],"formulations":[69],"include":[70,105],"basal":[71],"ascorbic":[73],"acid":[74],",":[75,80],"sodium":[76],"selenite,":[77],"recombinant":[78,88,204,206,243,261],"proteins":[79,207,262],"growth":[82,209,264],"factors,":[83],"contain":[87],"albumin":[89,244],"rapeseed":[91],"protein":[92],"isolates":[93],"(RPI)":[94],"replace":[96],"FBS,":[97],"respectively.":[98,230],"these":[100],"do":[103],"not":[104,112],"animal-sourced":[106],"components,":[107],"their":[108],"have":[111],"yet":[113],"been":[114],"investigated.":[115],"In":[116,198],"this":[117],"study,":[118],"life":[119],"cycle":[120],"assessment":[121],"(LCA)":[122],"was":[123,143,186],"performed":[124],"estimate":[126],"burdens":[129],"identify":[138,256],"hotspots":[139],"optimization.":[141],"Uncertainty":[142],"assessed":[144],"through":[145],"sensitivity":[146],"scenario":[148],"analyses,":[149],"as":[150,152],"well":[151],"Monte":[153],"Carlo":[154],"simulation.":[155],"Our":[156],"results":[157],"demonstrate":[158],"that":[159,194,234],"has":[161],"significantly":[162],"lower":[163,190],"compared":[166,192],"in":[169,245,266],"13":[170],"out":[171],"18":[173],"evaluated":[174],"impact":[175],"categories.":[176],"For":[177],"instance,":[178],"global":[180],"warming":[181],"potential":[182],"(GWP)":[183],"almost":[187],"five":[188],"times":[189],"when":[191],"against":[193],"Beefy-R,":[199],"despite":[200],"absence":[202],"albumin,":[205],"factors":[210,265],"were":[211],"hotspots,":[212],"accounting":[213],"41":[215],"%,":[216,218],"5.9":[217],"12":[220],"%":[221],"GWP,":[223],"land":[224],"use,":[225],"water":[227],"consumption":[228],"impacts,":[229],"This":[231],"study":[232],"confirms":[233],"RPI":[235],"can":[236],"be":[237],"more":[239],"substitute":[241],"formulations.":[250],"Additional":[251],"research":[252],"required":[254],"low-impact":[257],"alternatives":[258],"other":[260],"media.":[268]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
