{"id":"https://openalex.org/W4401049602","doi":"https://doi.org/10.1080/27694127.2024.2382659","title":"Autophagy of glycogen is non-selective in Komagataella phaffii","display_name":"Autophagy of glycogen is non-selective in Komagataella phaffii","publication_year":2024,"publication_date":"2024-07-27","ids":{"openalex":"https://openalex.org/W4401049602","doi":"https://doi.org/10.1080/27694127.2024.2382659","pmid":"https://pubmed.ncbi.nlm.nih.gov/39091992","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11290452"},"language":"en","primary_location":{"id":"doi:10.1080/27694127.2024.2382659","doi":"https://doi.org/10.1080/27694127.2024.2382659","is_oa":true,"landing_page_url":"https://doi.org/10.1080/27694127.2024.2382659","pdf_url":null,"source":{"id":"https://openalex.org/S4387278989","display_name":"Autophagy Reports","issn_l":"2769-4127","issn":["2769-4127"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy Reports","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1080/27694127.2024.2382659","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075956912","display_name":"Taras Y. Nazarko","orcid":"https://orcid.org/0000-0001-5322-8496","observed_orcids":["https://orcid.org/0000-0001-5322-8496"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Taras Y. Nazarko","raw_affiliation_strings":["Department of Biology, Georgia State University, Atlanta, USA"],"raw_orcid":"https://orcid.org/0000-0001-5322-8496","affiliations":[{"raw_affiliation_string":"Department of Biology, Georgia State University, Atlanta, USA","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075956912"],"corresponding_institution_ids":["https://openalex.org/I181565077"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12604","display_name":"Glycogen Storage Diseases and Myoclonus","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycogen","display_name":"glycogen","score":0.7590000033378601},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.8539999723434448},{"id":"https://openalex.org/keywords/komagataella-phaffii","display_name":"Pichia pastoris","score":0.9139999747276306},{"id":"https://openalex.org/keywords/selective-autophagy","display_name":"selective autophagy","score":0.8510000109672546},{"id":"https://openalex.org/keywords/glycogen-granules","display_name":"glycogen granules","score":0.828000009059906},{"id":"https://openalex.org/keywords/vacuoles","display_name":"vacuoles","score":0.8339999914169312},{"id":"https://openalex.org/keywords/nitrogen-starvation","display_name":"nitrogen starvation","score":0.7409999966621399},{"id":"https://openalex.org/keywords/pompe-disease","display_name":"Pompe disease","score":0.859000027179718},{"id":"https://openalex.org/keywords/yeast-model","display_name":"yeast model","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.8812237977981567},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.41939088702201843},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37832990288734436},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37427443265914917},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3527058959007263},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.349767804145813},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2963845133781433},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1080/27694127.2024.2382659","doi":"https://doi.org/10.1080/27694127.2024.2382659","is_oa":true,"landing_page_url":"https://doi.org/10.1080/27694127.2024.2382659","pdf_url":null,"source":{"id":"https://openalex.org/S4387278989","display_name":"Autophagy Reports","issn_l":"2769-4127","issn":["2769-4127"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy Reports","raw_type":"journal-article"},{"id":"pmid:39091992","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39091992","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11290452","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11290452","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11290452/pdf/KAUO_3_2382659.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Autophagy Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:f5199e224d824f8b9808cc55836ee371","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/f5199e224d824f8b9808cc55836ee371","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Autophagy Reports, Vol 3, Iss 1 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/27694127.2024.2382659","doi":"https://doi.org/10.1080/27694127.2024.2382659","is_oa":true,"landing_page_url":"https://doi.org/10.1080/27694127.2024.2382659","pdf_url":null,"source":{"id":"https://openalex.org/S4387278989","display_name":"Autophagy Reports","issn_l":"2769-4127","issn":["2769-4127"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Autophagy Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G494486989","display_name":"Mechanisms of lipophagy, the selective autophagy of lipid droplets","funder_award_id":"R35GM119571","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320317015","display_name":"Alzheimer's Society","ror":"https://ror.org/0472gwq90"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401049602.pdf","grobid_xml":"https://content.openalex.org/works/W4401049602.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W4392550171"],"related_works":["https://openalex.org/W4392550171","https://openalex.org/W6973597313","https://openalex.org/W4407798782","https://openalex.org/W4403979264","https://openalex.org/W4281892643","https://openalex.org/W3174288279","https://openalex.org/W4395670748","https://openalex.org/W4304958866","https://openalex.org/W2023851699","https://openalex.org/W2807662729"],"abstract_inverted_index":{"Glycogen":[0,25],"is":[1,11,49,84],"an":[2],"important":[3],"reserve":[4],"polysaccharide":[5],"from":[6],"bacteria":[7],"to":[8,39,64,123,142],"human.":[9],"It":[10,61],"organized":[12],"in":[13,22,30,75,86,109,168],"glycogen":[14,108,128,138,166],"granules":[15,26,139],"that":[16,136,155],"also":[17],"contain":[18],"several":[19],"proteins":[20],"involved":[21],"their":[23],"metabolism.":[24],"can":[27],"be":[28,65,161],"mobilized":[29],"mammalian":[31,170],"lysosomes":[32],"and":[33,67,94,129],"yeast":[34,118],"vacuoles.":[35],"They":[36],"are":[37,99,140],"delivered":[38,141],"these":[40],"organelles":[41],"by":[42,102,145],"macroautophagy":[43],"(hereafter":[44],"autophagy).":[45],"However,":[46,78],"whether":[47],"this":[48,82,132,156],"a":[50,53,57,120],"selective":[51,66,71],"or":[52],"non-selective":[54,146],"process":[55],"remains":[56],"matter":[58],"of":[59,73,81,107,127,158],"debate.":[60],"was":[62],"proposed":[63],"called":[68],"\u201cglycophagy\u201d":[69],"(for":[70],"autophagy":[72,159],"glycogen)":[74],"mouse":[76],"liver.":[77],"the":[79,92,103,115,125,143,164],"evidence":[80],"selectivity":[83],"lacking":[85],"other":[87],"glycogen-rich":[88],"organs,":[89],"such":[90],"as":[91,119],"heart":[93],"skeletal":[95],"muscle,":[96],"which":[97],"both":[98],"heavily":[100],"impacted":[101],"aberrant":[104],"lysosomal":[105,165],"accumulation":[106],"Pompe":[110],"disease.":[111],"We":[112,153],"recently":[113],"developed":[114],"Komagataella":[116],"phaffii":[117],"simple":[121],"model":[122],"study":[124],"relationship":[126],"autophagy.":[130],"Using":[131],"model,":[133],"we":[134],"showed":[135],"cytosolic":[137],"vacuole":[144],"autophagy,":[147],"at":[148],"least":[149],"during":[150],"nitrogen":[151],"starvation.":[152],"speculate":[154],"type":[157],"might":[160],"responsible":[162],"for":[163],"turnover":[167],"non-hepatic":[169],"tissues.Abbreviations":[171],"GFP,":[172],"green":[173],"fluorescent":[174],"protein.":[175]},"counts_by_year":[{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-07-31T00:00:00"}