{"id":"https://openalex.org/W4401029616","doi":"https://doi.org/10.1111/pin.13469","title":"Histopathology of peritonitis due to infectious mononucleosis with background Chlamydia trachomatis infection: A case report and literature review","display_name":"Histopathology of peritonitis due to infectious mononucleosis with background Chlamydia trachomatis infection: A case report and literature review","publication_year":2024,"publication_date":"2024-07-26","ids":{"openalex":"https://openalex.org/W4401029616","doi":"https://doi.org/10.1111/pin.13469","pmid":"https://pubmed.ncbi.nlm.nih.gov/39056535"},"language":"en","primary_location":{"id":"doi:10.1111/pin.13469","doi":"https://doi.org/10.1111/pin.13469","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/pin.13469","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pin.13469","source":{"id":"https://openalex.org/S70002872","display_name":"Pathology International","issn_l":"1320-5463","issn":["1320-5463","1440-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathology International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pin.13469","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031416152","display_name":"Yuto Kaimi","orcid":"https://orcid.org/0000-0003-0606-7524","observed_orcids":["https://orcid.org/0000-0003-0606-7524"]},"institutions":[{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuto Kaimi","raw_affiliation_strings":["Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0003-0606-7524","affiliations":[{"raw_affiliation_string":"Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069850430","display_name":"Tomoaki Naka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoaki Naka","raw_affiliation_strings":["Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054549197","display_name":"Hiroshi Yoshida","orcid":"https://orcid.org/0000-0002-7569-7813","observed_orcids":["https://orcid.org/0000-0002-7569-7813"]},"institutions":[{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Yoshida","raw_affiliation_strings":["Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7569-7813","affiliations":[{"raw_affiliation_string":"Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073304279","display_name":"Masaya Uno","orcid":"https://orcid.org/0000-0001-8549-1635","observed_orcids":["https://orcid.org/0000-0001-8549-1635"]},"institutions":[{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaya Uno","raw_affiliation_strings":["Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049768782","display_name":"Akiko Miyagi Maeshima","orcid":"https://orcid.org/0000-0001-7251-7920","observed_orcids":["https://orcid.org/0000-0001-7251-7920"]},"institutions":[{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Akiko Miyagi Maeshima","raw_affiliation_strings":["Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0001-7251-7920","affiliations":[{"raw_affiliation_string":"Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049768782"],"corresponding_institution_ids":["https://openalex.org/I4405285273"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14818849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"74","issue":"10","first_page":"611","last_page":"617"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/infectious-mononucleosis","display_name":"infectious mononucleosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.9639999866485596},{"id":"https://openalex.org/keywords/peritonitis","display_name":"peritonitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/ascites","display_name":"ascites","score":0.9890000224113464},{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":0.972000002861023},{"id":"https://openalex.org/keywords/b-cell-lymphoproliferative-disorders","display_name":"B-cell lymphoproliferative disorders","score":0.8069999814033508},{"id":"https://openalex.org/keywords/peritoneal-biopsy","display_name":"peritoneal biopsy","score":0.7440000176429749},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.4659999907016754},{"id":"https://openalex.org/keywords/young-women","display_name":"young women","score":0.4359999895095825},{"id":"https://openalex.org/keywords/atypical-lymphocytosis","display_name":"atypical lymphocytosis","score":0.6769999861717224},{"id":"https://openalex.org/keywords/elevated-liver-enzymes","display_name":"elevated liver enzymes","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.6972313523292542},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6287950277328491},{"id":"https://openalex.org/C2776129502","wikidata":"https://www.wikidata.org/wiki/Q207367","display_name":"Mononucleosis","level":3,"score":0.6253972053527832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6156681776046753},{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.4820462167263031},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.45110124349594116},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.42439427971839905},{"id":"https://openalex.org/C2780494569","wikidata":"https://www.wikidata.org/wiki/Q5384031","display_name":"Epstein\u2013Barr virus infection","level":4,"score":0.4237237274646759},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36607879400253296},{"id":"https://openalex.org/C2781375147","wikidata":"https://www.wikidata.org/wiki/Q6900","display_name":"Epstein\u2013Barr virus","level":3,"score":0.2732345461845398},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23629212379455566},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.17313644289970398}],"mesh":[{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004854","descriptor_name":"Herpesvirus 4, Human","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007244","descriptor_name":"Infectious Mononucleosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007244","descriptor_name":"Infectious Mononucleosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007244","descriptor_name":"Infectious Mononucleosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/pin.13469","doi":"https://doi.org/10.1111/pin.13469","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/pin.13469","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pin.13469","source":{"id":"https://openalex.org/S70002872","display_name":"Pathology International","issn_l":"1320-5463","issn":["1320-5463","1440-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathology International","raw_type":"journal-article"},{"id":"pmid:39056535","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39056535","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathology international","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1111/pin.13469","doi":"https://doi.org/10.1111/pin.13469","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/pin.13469","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pin.13469","source":{"id":"https://openalex.org/S70002872","display_name":"Pathology International","issn_l":"1320-5463","issn":["1320-5463","1440-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pathology International","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401029616.pdf","grobid_xml":"https://content.openalex.org/works/W4401029616.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W145712263","https://openalex.org/W151657078","https://openalex.org/W1597693535","https://openalex.org/W1999852381","https://openalex.org/W2019239918","https://openalex.org/W2039643944","https://openalex.org/W2061217342","https://openalex.org/W2082284469","https://openalex.org/W2098087204","https://openalex.org/W2114890741","https://openalex.org/W2129961222","https://openalex.org/W2161790138","https://openalex.org/W2261772206","https://openalex.org/W2322690467","https://openalex.org/W2324451125","https://openalex.org/W2806864917","https://openalex.org/W2998971528","https://openalex.org/W3128678924","https://openalex.org/W4386877890"],"related_works":["https://openalex.org/W2061217342","https://openalex.org/W4394743779","https://openalex.org/W2980036646","https://openalex.org/W1999852381","https://openalex.org/W2017815410","https://openalex.org/W2086592964","https://openalex.org/W4210959537","https://openalex.org/W2512962102","https://openalex.org/W1966322319","https://openalex.org/W3023466405"],"abstract_inverted_index":{"Epstein-Barr":[0],"virus":[1],"(EBV)":[2],"is":[3,26],"a":[4,27,35,45,49,78,108,191],"major":[5],"cause":[6],"of":[7,38,104,115,124,136,153],"infectious":[8],"mononucleosis":[9],"(IM),":[10],"characterized":[11],"by":[12,158],"fever,":[13],"fatigue,":[14],"sore":[15],"throat,":[16],"lymphadenopathy,":[17],"atypical":[18,64],"lymphocytosis,":[19],"and":[20,42,58,70,91,106,122,133,176],"elevated":[21,71],"liver":[22,72],"enzymes.":[23,73],"However,":[24],"ascites":[25,41,90,174],"rare":[28,36],"complication":[29],"associated":[30],"with":[31,40,56,182,197],"IM.":[32],"We":[33],"present":[34],"case":[37],"IM":[39,105,186],"peritonitis":[43,181],"in":[44,66,167,194],"patient":[46],"who":[47],"underwent":[48],"peritoneal":[50],"biopsy.":[51],"A":[52],"20-year-old":[53],"woman":[54],"presented":[55],"fatigue":[57],"abdominal":[59],"distension.":[60],"Laboratory":[61],"examination":[62],"revealed":[63,77,88],"lymphocytes":[65],"peripheral":[67],"blood":[68],"(54%)":[69],"EBV":[74],"serological":[75],"tests":[76],"recent":[79],"primary":[80],"infection":[81],"(EBV":[82],"VCA":[83],"IgM":[84],"1:160).":[85],"Computed":[86],"tomography":[87],"moderate":[89],"peritonitis.":[92],"Adenocarcinoma":[93],"was":[94,111,179],"suspected":[95],"based":[96],"on":[97],"the":[98,119,125,177],"ascites'":[99],"cytology.":[100],"Considering":[101],"possible":[102],"complications":[103],"adenocarcinoma,":[107],"laparoscopic":[109],"biopsy":[110,116],"performed.":[112],"Histological":[113],"findings":[114],"specimens":[117],"from":[118],"peritoneum,":[120],"omentum,":[121],"fimbria":[123],"fallopian":[126],"tube":[127],"demonstrated":[128],"severe":[129],"inflammatory":[130],"cell":[131],"infiltration":[132],"focal":[134],"aggregation":[135],"large":[137],"EBV-encoded":[138],"RNA-1":[139],"(EBER1)-positive":[140],"B":[141],"cells,":[142],"mimicking":[143],"EBV-positive":[144],"polymorphous":[145],"B-cell":[146],"lymphoproliferative":[147],"disorder.":[148],"Furthermore,":[149],"intracytoplasmic":[150],"inclusion":[151],"bodies":[152],"Chlamydia":[154],"trachomatis":[155,166,184],"were":[156],"observed":[157],"immunohistochemistry.":[159],"Real-time":[160],"polymerase":[161],"chain":[162],"reaction":[163],"detected":[164],"C.":[165,183],"cervical":[168],"secretions.":[169],"Two":[170],"months":[171],"after":[172],"laparoscopy,":[173],"decreased,":[175],"diagnosis":[178,193],"IM-associated":[180],"infection.":[185],"should":[187],"be":[188],"considered":[189],"as":[190],"differential":[192],"young":[195],"patients":[196],"ascites.":[198]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-07-27T00:00:00"}