{"id":"https://openalex.org/W4401012242","doi":"https://doi.org/10.1186/s12864-024-10606-6","title":"Chlamydia suis undergoes interclade recombination promoting Tet-island exchange","display_name":"Chlamydia suis undergoes interclade recombination promoting Tet-island exchange","publication_year":2024,"publication_date":"2024-07-26","ids":{"openalex":"https://openalex.org/W4401012242","doi":"https://doi.org/10.1186/s12864-024-10606-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/39060998","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11282597"},"language":"en","primary_location":{"id":"doi:10.1186/s12864-024-10606-6","doi":"https://doi.org/10.1186/s12864-024-10606-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-024-10606-6","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-024-10606-6","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-024-10606-6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071441030","display_name":"Helena M. B. Seth-Smith","orcid":"https://orcid.org/0000-0002-6082-5114","observed_orcids":["https://orcid.org/0000-0002-6082-5114"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Helena Seth-Smith","raw_affiliation_strings":["Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-6082-5114","affiliations":[{"raw_affiliation_string":"Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086536359","display_name":"Sankhya Bommana","orcid":"https://orcid.org/0000-0002-4469-7925","observed_orcids":["https://orcid.org/0000-0002-4469-7925"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210110664","display_name":"University of California San Francisco Medical Center","ror":"https://ror.org/01t8svj65","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210110664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sankhya Bommana","raw_affiliation_strings":["Division of Infectious Diseases and Global Health, Departments of Medicine and Pediatrics, University of California San Francisco School of Medicine, San Francisco, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-4469-7925","affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Global Health, Departments of Medicine and Pediatrics, University of California San Francisco School of Medicine, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4210110664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028181302","display_name":"Deborah Dean","orcid":"https://orcid.org/0000-0002-4490-1746","observed_orcids":["https://orcid.org/0000-0002-4490-1746","https://orcid.org/0000-0003-3847-8838"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210110664","display_name":"University of California San Francisco Medical Center","ror":"https://ror.org/01t8svj65","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210110664"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah Dean","raw_affiliation_strings":["Division of Infectious Diseases and Global Health, Departments of Medicine and Pediatrics, University of California San Francisco School of Medicine, San Francisco, CA, USA","Joint Graduate Program in Bioengineering, University of California Berkeley, University of California San Francisco, Berkeley and San Francisco, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-4490-1746","affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Global Health, Departments of Medicine and Pediatrics, University of California San Francisco School of Medicine, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4210110664"]},{"raw_affiliation_string":"Joint Graduate Program in Bioengineering, University of California Berkeley, University of California San Francisco, Berkeley and San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050672427","display_name":"Timothy D. Read","orcid":"https://orcid.org/0000-0001-8966-9680","observed_orcids":["https://orcid.org/0000-0001-8966-9680"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy D. Read","raw_affiliation_strings":["Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA","Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8966-9680","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081508064","display_name":"Hanna Marti","orcid":"https://orcid.org/0000-0002-8398-4708","observed_orcids":["https://orcid.org/0000-0002-8398-4708"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Hanna Marti","raw_affiliation_strings":["Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland. hanna.marti@uzh.ch","Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-8398-4708","affiliations":[{"raw_affiliation_string":"Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland. hanna.marti@uzh.ch","institution_ids":["https://openalex.org/I202697423"]},{"raw_affiliation_string":"Institute of Veterinary Pathology, University of Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5081508064"],"corresponding_institution_ids":["https://openalex.org/I202697423"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2913,"currency":"EUR","value_usd":3141},"fwci":0.7017,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65249114,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"25","issue":"1","first_page":"724","last_page":"724"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.3034999966621399,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.3034999966621399,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.19130000472068787,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.16110000014305115,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chlamydia-suis","display_name":"Chlamydia suis","score":1.0},{"id":"https://openalex.org/keywords/tetracycline-resistance","display_name":"tetracycline resistance","score":0.8330000042915344},{"id":"https://openalex.org/keywords/genomic-islands","display_name":"genomic islands","score":0.6140000224113464},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"horizontal gene transfer","score":0.9789999723434448},{"id":"https://openalex.org/keywords/chlamydiaceae","display_name":"Chlamydiaceae","score":0.7979999780654907},{"id":"https://openalex.org/keywords/pigs","display_name":"pigs","score":0.49300000071525574},{"id":"https://openalex.org/keywords/field-isolates","display_name":"field isolates","score":0.593999981880188},{"id":"https://openalex.org/keywords/phylogeny","display_name":"phylogeny","score":0.6269999742507935},{"id":"https://openalex.org/keywords/rifampicin-resistance","display_name":"rifampicin resistance","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.892545759677887},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6173754334449768},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5587095618247986},{"id":"https://openalex.org/C2777038808","wikidata":"https://www.wikidata.org/wiki/Q13474598","display_name":"Chlamydiaceae","level":3,"score":0.5150189399719238},{"id":"https://openalex.org/C156695909","wikidata":"https://www.wikidata.org/wiki/Q3373825","display_name":"Recombination","level":3,"score":0.5022792816162109},{"id":"https://openalex.org/C2780258820","wikidata":"https://www.wikidata.org/wiki/Q5195454","display_name":"Genomic island","level":4,"score":0.5006449222564697},{"id":"https://openalex.org/C2780923616","wikidata":"https://www.wikidata.org/wiki/Q193045","display_name":"Tetracycline","level":3,"score":0.4950098395347595},{"id":"https://openalex.org/C102744134","wikidata":"https://www.wikidata.org/wiki/Q22280388","display_name":"Homologous recombination","level":3,"score":0.46626266837120056},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.4491646885871887},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.39018014073371887},{"id":"https://openalex.org/C2780122209","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia","level":2,"score":0.26464203000068665},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.07927045226097107}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002689","descriptor_name":"Chlamydia","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013753","descriptor_name":"Tetracycline Resistance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022761","descriptor_name":"Gene Transfer, Horizontal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044404","descriptor_name":"Genomic Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1186/s12864-024-10606-6","doi":"https://doi.org/10.1186/s12864-024-10606-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-024-10606-6","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-024-10606-6","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11282597","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11282597","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11282597/pdf/12864_2024_Article_10606.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"Text"},{"id":"pmid:39060998","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39060998","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC genomics","raw_type":"Journal Article"},{"id":"pmh:oai:www.zora.uzh.ch:265048","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/id/eprint/265048/1/12864_2024_Article_10606.pdf","pdf_url":"https://www.zora.uzh.ch/id/eprint/265048/1/12864_2024_Article_10606.pdf","source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Seth-Smith, Helena; Bommana, Sankhya; Dean, Deborah; Read, Timothy D; Marti, Hanna (2024). Chlamydia suis undergoes interclade recombination promoting Tet-island exchange. BMC Genomics, 25(1):724.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt8pb6k1dz","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/8pb6k1dz","pdf_url":"https://escholarship.org/uc/item/8pb6k1dz","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Genomics, vol 25, iss 1","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:b16ff1c3689f425b8cc6c54ac1a5c52d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b16ff1c3689f425b8cc6c54ac1a5c52d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Genomics, Vol 25, Iss 1, Pp 1-7 (2024)","raw_type":"article"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/223322","doi":null,"is_oa":true,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/223322","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Seth-Smith, H., Bommana, S., Dean, D., Read, T. D., & Marti, H. (2024). Chlamydia suis undergoes interclade recombination promoting Tet-island exchange. BMC Genomics, 25, 724. https://doi.org/10.1186/s12864-024-10606-6","raw_type":"Journal Article"},{"id":"doi:10.5167/uzh-265048","doi":"https://doi.org/10.5167/uzh-265048","is_oa":true,"landing_page_url":"https://doi.org/10.5167/uzh-265048","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1186/s12864-024-10606-6","doi":"https://doi.org/10.1186/s12864-024-10606-6","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-024-10606-6","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-024-10606-6","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4152814798","display_name":null,"funder_award_id":"323530","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G6553689411","display_name":"Understanding the transmission mechanism of the tetracycline resistance gene C (tetC) in Chlamydia suis","funder_award_id":"177579","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320325165","display_name":"Schweizerische Akademie der Medizinischen Wissenschaften","ror":"https://ror.org/011cav305"},{"id":"https://openalex.org/F4320336859","display_name":"Functional Genomics Center Zurich","ror":"https://ror.org/04tgr1802"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4401012242.pdf","grobid_xml":"https://content.openalex.org/works/W4401012242.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1972145956","https://openalex.org/W2009606240","https://openalex.org/W2039978286","https://openalex.org/W2053292987","https://openalex.org/W2054120191","https://openalex.org/W2096093282","https://openalex.org/W2109478863","https://openalex.org/W2112217212","https://openalex.org/W2115140994","https://openalex.org/W2117678274","https://openalex.org/W2132926880","https://openalex.org/W2170488656","https://openalex.org/W2170551597","https://openalex.org/W2170964688","https://openalex.org/W2179708451","https://openalex.org/W2287520872","https://openalex.org/W2512427890","https://openalex.org/W2524786991","https://openalex.org/W2593666742","https://openalex.org/W2893947770","https://openalex.org/W2949182334","https://openalex.org/W2950753995","https://openalex.org/W2973043909","https://openalex.org/W2981607390","https://openalex.org/W2981774759","https://openalex.org/W3176627386","https://openalex.org/W4221022280"],"related_works":["https://openalex.org/W6902284167","https://openalex.org/W2524786991","https://openalex.org/W2593666742","https://openalex.org/W2115140994","https://openalex.org/W200711523","https://openalex.org/W2109478863","https://openalex.org/W3176627386","https://openalex.org/W7096224635","https://openalex.org/W2512427890","https://openalex.org/W2146288037"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"obligate":[2],"intracellular":[3],"bacterial":[4],"family":[5,39,77],"Chlamydiaceae":[6,38,76],"comprises":[7],"a":[8,48,72,79,114,219,279],"number":[9],"of":[10,30,36,56,68,117,121,141,162,168,173,186,195,230,250,264,270],"different":[11],"species":[12,35],"that":[13,65,97,159,172,203,238,261],"cause":[14],"disease":[15],"in":[16,26,108,133,150,198,213,247,267],"various":[17],"vertebrate":[18],"hosts":[19],"including":[20],"humans.":[21],"Chlamydia":[22],"suis,":[23],"primarily":[24],"found":[25,158,237],"the":[27,33,37,54,66,69,75,118,122,160,166,169,174,184,193,205,227,233,242,251,259,262],"gastrointestinal":[28],"tract":[29],"pigs,":[31],"is":[32,104],"only":[34],"to":[40,112,132,202,226],"have":[41,63,95],"naturally":[42],"gained":[43],"tetracycline":[44,220],"resistance":[45],"(TetR),":[46],"through":[47,88,275],"genomic":[49],"island":[50],"(Tet-island),":[51],"integrated":[52],"into":[53],"middle":[55],"chromosomal":[57],"invasin-like":[58],"gene":[59,283],"inv.":[60],"Previous":[61],"studies":[62,94],"hypothesised":[64],"uptake":[67],"Tet-island":[70,98,170,243,252],"from":[71],"host":[73],"outside":[74],"was":[78,111],"unique":[80],"event,":[81],"followed":[82],"by":[83],"spread":[84],"among":[85,124],"C.":[86,101,127,142,271],"suis":[87,102,128,143,272],"homologous":[89],"recombination.":[90],"In":[91],"vitro":[92],"recombination":[93,120,178,231,277],"shown":[96],"exchange":[99],"between":[100,192],"strains":[103,130,145,200,266],"possible.":[105],"Our":[106,256],"aim":[107],"this":[109],"study":[110,257],"gain":[113],"deeper":[115],"understanding":[116],"interclade":[119,239,276],"Tet-island,":[123],"currently":[125],"circulating":[126],"field":[129,144,206],"compared":[131,201],"vitro-generated":[134,151,199,214],"recombinants,":[135],"using":[136],"published":[137],"whole":[138,175],"genome":[139],"sequences":[140],"(n":[146,153],"=":[147,154],"35)":[148],"and":[149,221],"recombinants":[152,215],"63).":[155],"RESULTS:":[156],"We":[157],"phylogeny":[161,167],"inv":[163],"better":[164],"reflected":[165],"than":[171,180,253],"genome,":[176],"supporting":[177],"rather":[179],"site-specific":[181],"insertion":[182],"as":[183],"means":[185],"transfer.":[187],"There":[188],"were":[189,216,244],"considerable":[190],"differences":[191,209],"distribution":[194],"recombinations":[196,240],"within":[197,204],"strains.":[207],"These":[208],"are":[210],"likely":[211],"because":[212],"selected":[217],"for":[218],"rifamycin/rifampicin":[222],"resistant":[223],"background,":[224],"leading":[225],"largest":[228],"peak":[229],"across":[232,241],"Tet-island.":[234],"Finally,":[235],"we":[236],"more":[245],"variable":[246],"length":[248],"downstream":[249],"upstream.":[254],"CONCLUSIONS:":[255],"supports":[258],"hypothesis":[260],"occurrence":[263],"TetR":[265],"both":[268],"clades":[269],"came":[273],"about":[274],"after":[278],"single":[280],"ancestral":[281],"horizontal":[282],"transfer":[284],"event.":[285]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-07-27T00:00:00"}