{"id":"https://openalex.org/W4400974149","doi":"https://doi.org/10.3390/obesities4030020","title":"The Metabolic Syndrome: An Overview and Proposed Mechanisms","display_name":"The Metabolic Syndrome: An Overview and Proposed Mechanisms","publication_year":2024,"publication_date":"2024-07-22","ids":{"openalex":"https://openalex.org/W4400974149","doi":"https://doi.org/10.3390/obesities4030020"},"language":"en","primary_location":{"id":"doi:10.3390/obesities4030020","doi":"https://doi.org/10.3390/obesities4030020","is_oa":true,"landing_page_url":"https://doi.org/10.3390/obesities4030020","pdf_url":null,"source":{"id":"https://openalex.org/S4210198178","display_name":"Obesities","issn_l":"2673-4168","issn":["2673-4168"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesities","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/obesities4030020","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085340639","display_name":"Fernanda Santos Thomaz","orcid":"https://orcid.org/0000-0003-2480-7290","observed_orcids":["https://orcid.org/0000-0003-2480-7290"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Fernanda Santos Thomaz","raw_affiliation_strings":["School of Chemistry and Molecular Bioscience, University of Queensland, St. Lucia, QLD 4067, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry and Molecular Bioscience, University of Queensland, St. Lucia, QLD 4067, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061316705","display_name":"Oliver Dean John","orcid":"https://orcid.org/0000-0001-5035-1878","observed_orcids":["https://orcid.org/0000-0001-5035-1878"]},"institutions":[{"id":"https://openalex.org/I4210099732","display_name":"Asia Pacific International University","ror":"https://ror.org/00m2sk374","country_code":"TH","type":"education","lineage":["https://openalex.org/I4210099732"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Oliver Dean John","raw_affiliation_strings":["Faculty of Science, Asia-Pacific International University, Muak Lek, Saraburi 18180, Thailand"],"raw_orcid":"https://orcid.org/0000-0001-5035-1878","affiliations":[{"raw_affiliation_string":"Faculty of Science, Asia-Pacific International University, Muak Lek, Saraburi 18180, Thailand","institution_ids":["https://openalex.org/I4210099732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074006613","display_name":"Payel Sinha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185523456","display_name":"University of Southern Queensland","ror":"https://ror.org/04sjbnx57","country_code":"AU","type":"education","lineage":["https://openalex.org/I185523456"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Payel Sinha","raw_affiliation_strings":["Centre for Agricultural Engineering, University of Southern Queensland, Toowoomba, QLD 4350, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Agricultural Engineering, University of Southern Queensland, Toowoomba, QLD 4350, Australia","institution_ids":["https://openalex.org/I185523456"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038686574","display_name":"Siti Raihanah Shafie","orcid":"https://orcid.org/0000-0003-2983-7536","observed_orcids":["https://orcid.org/0000-0003-2983-7536"]},"institutions":[{"id":"https://openalex.org/I130343225","display_name":"Universiti Putra Malaysia","ror":"https://ror.org/02e91jd64","country_code":"MY","type":"education","lineage":["https://openalex.org/I130343225"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Siti Raihanah Shafie","raw_affiliation_strings":["Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia"],"raw_orcid":"https://orcid.org/0000-0003-2983-7536","affiliations":[{"raw_affiliation_string":"Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia","institution_ids":["https://openalex.org/I130343225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030304038","display_name":"Simon Worrall","orcid":"https://orcid.org/0000-0001-5902-5809","observed_orcids":["https://orcid.org/0000-0001-5902-5809"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Simon Worrall","raw_affiliation_strings":["School of Chemistry and Molecular Bioscience, University of Queensland, St. Lucia, QLD 4067, Australia"],"raw_orcid":"https://orcid.org/0000-0001-5902-5809","affiliations":[{"raw_affiliation_string":"School of Chemistry and Molecular Bioscience, University of Queensland, St. Lucia, QLD 4067, Australia","institution_ids":["https://openalex.org/I165143802"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5085340639"],"corresponding_institution_ids":["https://openalex.org/I165143802"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1137},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1137},"fwci":7.7403,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.98109508,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"4","issue":"3","first_page":"226","last_page":"255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9398999810218811,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.039799999445676804,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":1.0},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.996999979019165},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9620000123977661},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lipoprotein-metabolism","display_name":"lipoprotein metabolism","score":0.9800000190734863},{"id":"https://openalex.org/keywords/ferroptosis","display_name":"ferroptosis","score":0.8889999985694885},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":0.8579999804496765},{"id":"https://openalex.org/keywords/lipotoxicity","display_name":"lipotoxicity","score":0.9760000109672546},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.9789999723434448},{"id":"https://openalex.org/keywords/adipose-tissue-macrophages","display_name":"adipose tissue macrophages","score":0.9980000257492065},{"id":"https://openalex.org/keywords/metabolic-crosstalk","display_name":"metabolic crosstalk","score":0.9309999942779541},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.7144006490707397},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.6814796328544617},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.6617156267166138},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5709379315376282},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5445088148117065},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.5090991854667664},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.49604806303977966},{"id":"https://openalex.org/C2777693730","wikidata":"https://www.wikidata.org/wiki/Q1140549","display_name":"Abdominal obesity","level":4,"score":0.47458386421203613},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.45731210708618164},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.45294803380966187},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.43876829743385315},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.415335088968277},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.2799586057662964},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27811723947525024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22558832168579102},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20565801858901978},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/obesities4030020","doi":"https://doi.org/10.3390/obesities4030020","is_oa":true,"landing_page_url":"https://doi.org/10.3390/obesities4030020","pdf_url":null,"source":{"id":"https://openalex.org/S4210198178","display_name":"Obesities","issn_l":"2673-4168","issn":["2673-4168"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesities","raw_type":"journal-article"},{"id":"pmh:oai:psasir.upm.edu.my:118284","doi":null,"is_oa":true,"landing_page_url":"http://psasir.upm.edu.my/id/eprint/118284/1/118284.pdf","pdf_url":"http://psasir.upm.edu.my/id/eprint/118284/1/118284.pdf","source":{"id":"https://openalex.org/S4377196260","display_name":"Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I130343225","host_organization_name":"Universiti Putra Malaysia","host_organization_lineage":["https://openalex.org/I130343225"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:cf4549c256674749ba2009dca84a75cb","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cf4549c256674749ba2009dca84a75cb","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Obesities, Vol 4, Iss 3, Pp 226-255 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/obesities4030020","doi":"https://doi.org/10.3390/obesities4030020","is_oa":true,"landing_page_url":"https://doi.org/10.3390/obesities4030020","pdf_url":null,"source":{"id":"https://openalex.org/S4210198178","display_name":"Obesities","issn_l":"2673-4168","issn":["2673-4168"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesities","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400974149.pdf","grobid_xml":"https://content.openalex.org/works/W4400974149.grobid-xml"},"referenced_works_count":290,"referenced_works":["https://openalex.org/W140545298","https://openalex.org/W207584000","https://openalex.org/W226375095","https://openalex.org/W231592701","https://openalex.org/W344801229","https://openalex.org/W392890894","https://openalex.org/W636215702","https://openalex.org/W795119008","https://openalex.org/W1012070930","https://openalex.org/W1465091374","https://openalex.org/W1501986283","https://openalex.org/W1508245019","https://openalex.org/W1511417959","https://openalex.org/W1607892649","https://openalex.org/W1800853464","https://openalex.org/W1954270231","https://openalex.org/W1969643223","https://openalex.org/W1970225752","https://openalex.org/W1970377569","https://openalex.org/W1971915082","https://openalex.org/W1972068188","https://openalex.org/W1972900673","https://openalex.org/W1973610105","https://openalex.org/W1974020172","https://openalex.org/W1975610756","https://openalex.org/W1976829005","https://openalex.org/W1981711832","https://openalex.org/W1984438362","https://openalex.org/W1985538633","https://openalex.org/W1987601141","https://openalex.org/W1987954357","https://openalex.org/W1990834174","https://openalex.org/W1990898737","https://openalex.org/W1991760464","https://openalex.org/W1992292929","https://openalex.org/W1998836938","https://openalex.org/W2000205368","https://openalex.org/W2001986473","https://openalex.org/W2007306221","https://openalex.org/W2009354643","https://openalex.org/W2011185005","https://openalex.org/W2011555594","https://openalex.org/W2013753604","https://openalex.org/W2016399806","https://openalex.org/W2021523302","https://openalex.org/W2022338332","https://openalex.org/W2025607561","https://openalex.org/W2026804593","https://openalex.org/W2030845044","https://openalex.org/W2031585142","https://openalex.org/W2035247356","https://openalex.org/W2035898219","https://openalex.org/W2042229706","https://openalex.org/W2043348456","https://openalex.org/W2046406719","https://openalex.org/W2051040739","https://openalex.org/W2051522090","https://openalex.org/W2051903648","https://openalex.org/W2052914236","https://openalex.org/W2053154947","https://openalex.org/W2056696439","https://openalex.org/W2061421745","https://openalex.org/W2068817437","https://openalex.org/W2070089423","https://openalex.org/W2071718508","https://openalex.org/W2076310317","https://openalex.org/W2079195246","https://openalex.org/W2082468819","https://openalex.org/W2082776945","https://openalex.org/W2083585500","https://openalex.org/W2088359631","https://openalex.org/W2088744527","https://openalex.org/W2093089132","https://openalex.org/W2093386835","https://openalex.org/W2095324809","https://openalex.org/W2096205853","https://openalex.org/W2100233996","https://openalex.org/W2100784798","https://openalex.org/W2102946509","https://openalex.org/W2116006961","https://openalex.org/W2120559894","https://openalex.org/W2122367003","https://openalex.org/W2125689907","https://openalex.org/W2126218858","https://openalex.org/W2128190429","https://openalex.org/W2129377253","https://openalex.org/W2130064617","https://openalex.org/W2130092335","https://openalex.org/W2134673828","https://openalex.org/W2140406095","https://openalex.org/W2140777557","https://openalex.org/W2141076601","https://openalex.org/W2141998683","https://openalex.org/W2146466098","https://openalex.org/W2147821881","https://openalex.org/W2148403865","https://openalex.org/W2159586070","https://openalex.org/W2162940414","https://openalex.org/W2165611065","https://openalex.org/W2172053085","https://openalex.org/W2189205651","https://openalex.org/W2232504117","https://openalex.org/W2274178968","https://openalex.org/W2526536530","https://openalex.org/W2534555913","https://openalex.org/W2585652554","https://openalex.org/W2593099486","https://openalex.org/W2607482065","https://openalex.org/W2610797963","https://openalex.org/W2620436731","https://openalex.org/W2752320193","https://openalex.org/W2762198627","https://openalex.org/W2766921609","https://openalex.org/W2770916293","https://openalex.org/W2789432975","https://openalex.org/W2793512096","https://openalex.org/W2794678145","https://openalex.org/W2799659527","https://openalex.org/W2800088564","https://openalex.org/W2800658350","https://openalex.org/W2800884547","https://openalex.org/W2803317673","https://openalex.org/W2889143556","https://openalex.org/W2890131318","https://openalex.org/W2894233329","https://openalex.org/W2894986562","https://openalex.org/W2904246900","https://openalex.org/W2909981430","https://openalex.org/W2919387066","https://openalex.org/W2921646079","https://openalex.org/W2939175683","https://openalex.org/W2941491147","https://openalex.org/W2947925531","https://openalex.org/W2948039315","https://openalex.org/W2949177955","https://openalex.org/W2956930953","https://openalex.org/W2961328380","https://openalex.org/W2978150420","https://openalex.org/W2978840913","https://openalex.org/W2987292023","https://openalex.org/W2997323331","https://openalex.org/W3001490928","https://openalex.org/W3012295934","https://openalex.org/W3012329906","https://openalex.org/W3013314180","https://openalex.org/W3014223308","https://openalex.org/W3019705932","https://openalex.org/W3024380269","https://openalex.org/W3041210126","https://openalex.org/W3042494222","https://openalex.org/W3046962722","https://openalex.org/W3048556449","https://openalex.org/W3090558236","https://openalex.org/W3092631461","https://openalex.org/W3092998012","https://openalex.org/W3104014022","https://openalex.org/W3109716884","https://openalex.org/W3119247691","https://openalex.org/W3120744005","https://openalex.org/W3122153668","https://openalex.org/W3126868240","https://openalex.org/W3129074300","https://openalex.org/W3132170817","https://openalex.org/W3132255180","https://openalex.org/W3134632803","https://openalex.org/W3153618412","https://openalex.org/W3155528909","https://openalex.org/W3158281207","https://openalex.org/W3162305544","https://openalex.org/W3165301388","https://openalex.org/W3169621007","https://openalex.org/W3174413811","https://openalex.org/W3176281729","https://openalex.org/W3179110972","https://openalex.org/W3182892402","https://openalex.org/W3194308116","https://openalex.org/W3196858127","https://openalex.org/W3197752975","https://openalex.org/W3198259760","https://openalex.org/W3199622092","https://openalex.org/W3201187022","https://openalex.org/W3205422331","https://openalex.org/W3205952484","https://openalex.org/W3207756665","https://openalex.org/W3207848283","https://openalex.org/W3212959806","https://openalex.org/W3216899816","https://openalex.org/W3216955477","https://openalex.org/W4200140669","https://openalex.org/W4200619278","https://openalex.org/W4206243999","https://openalex.org/W4206724673","https://openalex.org/W4207036939","https://openalex.org/W4210582716","https://openalex.org/W4214520246","https://openalex.org/W4220847559","https://openalex.org/W4220879829","https://openalex.org/W4220965411","https://openalex.org/W4224218598","https://openalex.org/W4225746642","https://openalex.org/W4225985147","https://openalex.org/W4238567307","https://openalex.org/W4280560819","https://openalex.org/W4281698709","https://openalex.org/W4281850484","https://openalex.org/W4284890877","https://openalex.org/W4285742736","https://openalex.org/W4290653248","https://openalex.org/W4293176551","https://openalex.org/W4293723582","https://openalex.org/W4294044968","https://openalex.org/W4294168213","https://openalex.org/W4294739761","https://openalex.org/W4295758683","https://openalex.org/W4300689649","https://openalex.org/W4303633910","https://openalex.org/W4307229478","https://openalex.org/W4307313355","https://openalex.org/W4307581221","https://openalex.org/W4308365150","https://openalex.org/W4308724314","https://openalex.org/W4310999169","https://openalex.org/W4312094691","https://openalex.org/W4312114245","https://openalex.org/W4312196136","https://openalex.org/W4313409528","https://openalex.org/W4313461270","https://openalex.org/W4317749697","https://openalex.org/W4318208160","https://openalex.org/W4318613259","https://openalex.org/W4321004410","https://openalex.org/W4321163868","https://openalex.org/W4321786273","https://openalex.org/W4323255431","https://openalex.org/W4323530524","https://openalex.org/W4324061320","https://openalex.org/W4360614496","https://openalex.org/W4366393083","https://openalex.org/W4366594842","https://openalex.org/W4367396610","https://openalex.org/W4367623942","https://openalex.org/W4376138860","https://openalex.org/W4377819991","https://openalex.org/W4378978906","https://openalex.org/W4380200767","https://openalex.org/W4380789025","https://openalex.org/W4382011091","https://openalex.org/W4382182252","https://openalex.org/W4382239618","https://openalex.org/W4384338818","https://openalex.org/W4385064298","https://openalex.org/W4385463045","https://openalex.org/W4385506229","https://openalex.org/W4386096664","https://openalex.org/W4386728322","https://openalex.org/W4386741787","https://openalex.org/W4387229859","https://openalex.org/W4387230110","https://openalex.org/W4387230320","https://openalex.org/W4387310201","https://openalex.org/W4387322431","https://openalex.org/W4387357759","https://openalex.org/W4387651658","https://openalex.org/W4388230704","https://openalex.org/W4388483256","https://openalex.org/W4388982160","https://openalex.org/W4389242691","https://openalex.org/W4389301829","https://openalex.org/W4389348751","https://openalex.org/W4389381603","https://openalex.org/W4389432272","https://openalex.org/W4389624871","https://openalex.org/W4390112952","https://openalex.org/W4390538301","https://openalex.org/W4390666969","https://openalex.org/W4390944282","https://openalex.org/W4391174695","https://openalex.org/W4391781492","https://openalex.org/W4391883674","https://openalex.org/W4392001777","https://openalex.org/W4392973253","https://openalex.org/W4393155483","https://openalex.org/W4393950442","https://openalex.org/W4393970961","https://openalex.org/W4394004582","https://openalex.org/W4394855511","https://openalex.org/W4396765020","https://openalex.org/W6681105747","https://openalex.org/W6847466302","https://openalex.org/W7099414481"],"related_works":["https://openalex.org/W7130650556","https://openalex.org/W4390666969","https://openalex.org/W2095664708","https://openalex.org/W4416202995","https://openalex.org/W4405828520","https://openalex.org/W4378650290","https://openalex.org/W2330293594","https://openalex.org/W2212140938","https://openalex.org/W7133234201","https://openalex.org/W4323255431"],"abstract_inverted_index":{"Obesity":[0],"has":[1],"emerged":[2],"as":[3],"a":[4,22],"major":[5,70],"public":[6],"health":[7,26,71,150],"challenge":[8],"in":[9,87],"the":[10,15,57,77,97,108,113,133,146],"21st":[11],"century,":[12],"contributing":[13],"to":[14,62,89,96,126],"rising":[16],"prevalence":[17],"of":[18,24,53,59,68,79,99,110,115,148],"metabolic":[19,54,130],"syndrome":[20],"(MetS),":[21],"cluster":[23],"interrelated":[25],"risk":[27,151],"factors.":[28,152],"These":[29,101],"factors":[30],"include":[31,104],"obesity":[32],"or":[33],"abdominal":[34],"obesity,":[35],"type":[36],"2":[37],"diabetes":[38],"mellitus":[39],"(T2DM),":[40],"hypertension":[41],"(HTN),":[42],"and":[43,56,92,112,137,144],"dyslipidaemia.":[44],"In":[45],"this":[46,123],"review,":[47],"we":[48,74],"will":[49,75],"explore":[50],"important":[51],"aspects":[52],"regulation":[55],"dynamics":[58],"lipoprotein":[60],"metabolism":[61],"see":[63],"how":[64],"they":[65],"underlie":[66],"each":[67],"these":[69,121,149],"risks.":[72],"Additionally,":[73],"highlight":[76],"role":[78,114],"ferroptosis,":[80],"an":[81],"iron-dependent":[82],"regulated":[83],"cell":[84],"death":[85],"process,":[86],"relation":[88],"inflammatory":[90,102],"responses":[91,103],"its":[93],"critical":[94],"contribution":[95],"pathophysiology":[98],"MetS.":[100],"inflammasome":[105],"activation,":[106],"lipotoxicity,":[107],"influence":[109],"adipocytokines,":[111],"adipose":[116],"tissue":[117],"macrophages.":[118],"By":[119],"exploring":[120],"interconnections,":[122],"review":[124],"aims":[125],"provide":[127],"insights":[128],"into":[129],"crosstalk,":[131],"outline":[132],"pathological":[134],"mechanisms":[135],"occurring,":[136],"identify":[138],"potential":[139],"therapeutic":[140],"targets":[141],"for":[142],"managing":[143],"preventing":[145],"progression":[147]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":12}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-07-26T00:00:00"}
