{"id":"https://openalex.org/W4400966968","doi":"https://doi.org/10.1016/j.jep.2024.118617","title":"In vivo anti-gastric ulcer activity of 7-O-methyl aromadendrin and sakuranetin via mitigating inflammatory and oxidative stress trails","display_name":"In vivo anti-gastric ulcer activity of 7-O-methyl aromadendrin and sakuranetin via mitigating inflammatory and oxidative stress trails","publication_year":2024,"publication_date":"2024-07-23","ids":{"openalex":"https://openalex.org/W4400966968","doi":"https://doi.org/10.1016/j.jep.2024.118617","pmid":"https://pubmed.ncbi.nlm.nih.gov/39053715"},"language":"en","primary_location":{"id":"doi:10.1016/j.jep.2024.118617","doi":"https://doi.org/10.1016/j.jep.2024.118617","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jep.2024.118617","pdf_url":null,"source":{"id":"https://openalex.org/S29564236","display_name":"Journal of Ethnopharmacology","issn_l":"0378-8741","issn":["0378-8741","1872-7573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ethnopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061261953","display_name":"Dalia E. Ali","orcid":"https://orcid.org/0000-0001-5959-733X","observed_orcids":["https://orcid.org/0000-0001-5959-733X"]},"institutions":[{"id":"https://openalex.org/I146977602","display_name":"Pharos University in Alexandria","ror":"https://ror.org/04cgmbd24","country_code":"EG","type":"education","lineage":["https://openalex.org/I146977602"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Dalia E. Ali","raw_affiliation_strings":["Department of Pharmacognosy and Natural Products, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt"],"raw_orcid":"https://orcid.org/0000-0001-5959-733X","affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy and Natural Products, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt","institution_ids":["https://openalex.org/I146977602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060358836","display_name":"Riham A. El\u2010Shiekh","orcid":"https://orcid.org/0000-0002-3179-3352","observed_orcids":["https://orcid.org/0000-0002-3179-3352"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Riham A. El-Shiekh","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: riham.adel@pharma.cu.edu.eg"],"raw_orcid":"https://orcid.org/0000-0002-3179-3352","affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: riham.adel@pharma.cu.edu.eg","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029654007","display_name":"Maged A. El Sawy","orcid":"https://orcid.org/0000-0002-0495-1722","observed_orcids":["https://orcid.org/0000-0002-0495-1722"]},"institutions":[{"id":"https://openalex.org/I146977602","display_name":"Pharos University in Alexandria","ror":"https://ror.org/04cgmbd24","country_code":"EG","type":"education","lineage":["https://openalex.org/I146977602"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Maged A. El Sawy","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt","institution_ids":["https://openalex.org/I146977602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055544576","display_name":"Asmaa A. Khalifa","orcid":"https://orcid.org/0000-0003-2507-3188","observed_orcids":["https://orcid.org/0000-0003-2507-3188","https://orcid.org/0000-0002-1453-1991"]},"institutions":[{"id":"https://openalex.org/I146977602","display_name":"Pharos University in Alexandria","ror":"https://ror.org/04cgmbd24","country_code":"EG","type":"education","lineage":["https://openalex.org/I146977602"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Asmaa A. Khalifa","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt","institution_ids":["https://openalex.org/I146977602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026473018","display_name":"Samar S. Elblehi","orcid":"https://orcid.org/0000-0003-4939-1754","observed_orcids":["https://orcid.org/0000-0003-4939-1754"]},"institutions":[{"id":"https://openalex.org/I84524832","display_name":"Alexandria University","ror":"https://ror.org/00mzz1w90","country_code":"EG","type":"education","lineage":["https://openalex.org/I84524832"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Samar S. Elblehi","raw_affiliation_strings":["Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt","institution_ids":["https://openalex.org/I84524832"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033106809","display_name":"Nahed H. Elsokkary","orcid":"https://orcid.org/0000-0001-8720-4214","observed_orcids":["https://orcid.org/0000-0001-8720-4214"]},"institutions":[{"id":"https://openalex.org/I84524832","display_name":"Alexandria University","ror":"https://ror.org/00mzz1w90","country_code":"EG","type":"education","lineage":["https://openalex.org/I84524832"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Nahed H. Elsokkary","raw_affiliation_strings":["Department of Physiology, Faculty of Medicine, Alexandria University, Alexandria, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Faculty of Medicine, Alexandria University, Alexandria, Egypt","institution_ids":["https://openalex.org/I84524832"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009336309","display_name":"Mennatallah A. Ali","orcid":"https://orcid.org/0000-0003-0732-924X","observed_orcids":["https://orcid.org/0000-0003-0732-924X"]},"institutions":[{"id":"https://openalex.org/I146977602","display_name":"Pharos University in Alexandria","ror":"https://ror.org/04cgmbd24","country_code":"EG","type":"education","lineage":["https://openalex.org/I146977602"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mennatallah A. Ali","raw_affiliation_strings":["Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-0732-924X","affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt","institution_ids":["https://openalex.org/I146977602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5060358836"],"corresponding_institution_ids":["https://openalex.org/I145487455"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":4.1488,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.94599618,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"335","issue":null,"first_page":"118617","last_page":"118617"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.3935999870300293,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.3935999870300293,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.3285999894142151,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.05169999971985817,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sakuranetin","display_name":"sakuranetin","score":0.996999979019165},{"id":"https://openalex.org/keywords/gastroprotective-effect","display_name":"gastroprotection","score":0.8989999890327454},{"id":"https://openalex.org/keywords/ethanol-induced-gastric-lesions","display_name":"ethanol-induced gastric injury","score":0.968999981880188},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8489999771118164},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.46700000762939453},{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.7239999771118164},{"id":"https://openalex.org/keywords/cox-1","display_name":"cyclooxygenase-1","score":0.7850000262260437},{"id":"https://openalex.org/keywords/endothelial-nitric-oxide-synthase","display_name":"endothelial nitric oxide synthase","score":0.8659999966621399},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase","display_name":"inducible nitric oxide synthase","score":0.6460000276565552},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6060000061988831},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.8640000224113464},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.8420000076293945},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.503000020980835},{"id":"https://openalex.org/keywords/omeprazole","display_name":"omeprazole","score":0.7229999899864197},{"id":"https://openalex.org/keywords/eucalyptus","display_name":"Eucalyptus","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7048452496528625},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6542786359786987},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5230109095573425},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.49002349376678467},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.48247554898262024},{"id":"https://openalex.org/C2776672619","wikidata":"https://www.wikidata.org/wiki/Q7623456","display_name":"Stress ulcer","level":2,"score":0.4195857048034668},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4114888906478882},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3202287554740906},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3150618076324463},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2262142300605774},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.06093880534172058}],"mesh":[{"descriptor_ui":"D000094162","descriptor_name":"Phytoalexins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000897","descriptor_name":"Anti-Ulcer Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009853","descriptor_name":"Omeprazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013276","descriptor_name":"Stomach Ulcer","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jep.2024.118617","doi":"https://doi.org/10.1016/j.jep.2024.118617","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jep.2024.118617","pdf_url":null,"source":{"id":"https://openalex.org/S29564236","display_name":"Journal of Ethnopharmacology","issn_l":"0378-8741","issn":["0378-8741","1872-7573"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ethnopharmacology","raw_type":"journal-article"},{"id":"pmid:39053715","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39053715","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of ethnopharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W1538399032","https://openalex.org/W1586722842","https://openalex.org/W1700083195","https://openalex.org/W1775749144","https://openalex.org/W1803283971","https://openalex.org/W1928488802","https://openalex.org/W1932147595","https://openalex.org/W1956779813","https://openalex.org/W1967128906","https://openalex.org/W1968212151","https://openalex.org/W1974911268","https://openalex.org/W1980906720","https://openalex.org/W1990854097","https://openalex.org/W1993353815","https://openalex.org/W1995616574","https://openalex.org/W1997948464","https://openalex.org/W2005630003","https://openalex.org/W2014194037","https://openalex.org/W2024967754","https://openalex.org/W2026390908","https://openalex.org/W2030916015","https://openalex.org/W2032193394","https://openalex.org/W2042961772","https://openalex.org/W2065928443","https://openalex.org/W2066258000","https://openalex.org/W2066301620","https://openalex.org/W2075513485","https://openalex.org/W2095984439","https://openalex.org/W2107277218","https://openalex.org/W2107998704","https://openalex.org/W2112845321","https://openalex.org/W2115899272","https://openalex.org/W2118519973","https://openalex.org/W2120023438","https://openalex.org/W2136028161","https://openalex.org/W2144190078","https://openalex.org/W2145952115","https://openalex.org/W2154403139","https://openalex.org/W2155208388","https://openalex.org/W2221247071","https://openalex.org/W2326522084","https://openalex.org/W2332437538","https://openalex.org/W2483715050","https://openalex.org/W2497429637","https://openalex.org/W2556393896","https://openalex.org/W2610481895","https://openalex.org/W2749710857","https://openalex.org/W2790394240","https://openalex.org/W2905110859","https://openalex.org/W2916946280","https://openalex.org/W2971427106","https://openalex.org/W2996087077","https://openalex.org/W2998026041","https://openalex.org/W3006909126","https://openalex.org/W3020180709","https://openalex.org/W3036335000","https://openalex.org/W3037157510","https://openalex.org/W3154764063","https://openalex.org/W3174592289","https://openalex.org/W3175379777","https://openalex.org/W4285394905","https://openalex.org/W4289941229","https://openalex.org/W4292261386","https://openalex.org/W4297360972","https://openalex.org/W4308860993","https://openalex.org/W4312106825","https://openalex.org/W4313327813","https://openalex.org/W4319298385","https://openalex.org/W4376113237","https://openalex.org/W4388043432","https://openalex.org/W4392438326","https://openalex.org/W4400984314"],"related_works":["https://openalex.org/W2061396218","https://openalex.org/W4400251776","https://openalex.org/W2987817201","https://openalex.org/W2031579650","https://openalex.org/W7171486245","https://openalex.org/W4293083408","https://openalex.org/W7160062666","https://openalex.org/W4412692557","https://openalex.org/W1850974052","https://openalex.org/W2025375750"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-07-25T00:00:00"}