{"id":"https://openalex.org/W4400917811","doi":"https://doi.org/10.1128/spectrum.03946-23","title":"Maximum likelihood estimators for colony-forming units","display_name":"Maximum likelihood estimators for colony-forming units","publication_year":2024,"publication_date":"2024-07-23","ids":{"openalex":"https://openalex.org/W4400917811","doi":"https://doi.org/10.1128/spectrum.03946-23","pmid":"https://pubmed.ncbi.nlm.nih.gov/39041814","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11371269"},"language":"en","primary_location":{"id":"doi:10.1128/spectrum.03946-23","doi":"https://doi.org/10.1128/spectrum.03946-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/spectrum.03946-23","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1128/spectrum.03946-23","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030584398","display_name":"K. Michael Martini","orcid":"https://orcid.org/0000-0002-5946-1122","observed_orcids":["https://orcid.org/0000-0002-5946-1122"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"K. Michael Martini","raw_affiliation_strings":["Department of Physics, Emory University","Initiative in Theory and Modeling of Living Systems, Emory University","Department of Physics, Emory University, Atlanta, Georgia, USA","Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072277449","display_name":"Satya Spandana Boddu","orcid":"https://orcid.org/0000-0001-9727-2894","observed_orcids":["https://orcid.org/0000-0001-9727-2894"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Satya Spandana Boddu","raw_affiliation_strings":["Department of Physics, Emory University","Department of Physics, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071388278","display_name":"Ilya M. Nemenman","orcid":"https://orcid.org/0000-0003-3024-4244","observed_orcids":["https://orcid.org/0000-0003-3024-4244"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ilya Nemenman","raw_affiliation_strings":["Department of Biology, Emory University","Department of Physics, Emory University","Initiative in Theory and Modeling of Living Systems, Emory University","Department of Biology, Emory University, Atlanta, Georgia, USA","Department of Physics, Emory University, Atlanta, Georgia, USA","Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biology, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019789222","display_name":"Nic M. Vega","orcid":"https://orcid.org/0000-0002-9929-6109","observed_orcids":["https://orcid.org/0000-0002-9929-6109"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nic Vega","raw_affiliation_strings":["Department of Biology, Emory University","Department of Physics, Emory University","Initiative in Theory and Modeling of Living Systems, Emory University","Department of Biology, Emory University, Atlanta, Georgia, USA","Department of Physics, Emory University, Atlanta, Georgia, USA","Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Biology, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Physics, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Initiative in Theory and Modeling of Living Systems, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019789222","https://openalex.org/A5030584398"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":{"value":2500,"currency":"USD","value_usd":2500},"fwci":1.7215,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.88095238,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"12","issue":"9","first_page":"e0394623","last_page":"e0394623"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13500","display_name":"Probability and Statistical Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13500","display_name":"Probability and Statistical Research","score":0.5839999914169312,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10968","display_name":"Statistical Distribution Estimation and Applications","score":0.054999999701976776,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11791","display_name":"Microbial Community Ecology and Physiology","score":0.03229999914765358,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colony-forming-units","display_name":"colony-forming units","score":0.9890000224113464},{"id":"https://openalex.org/keywords/maximum-likelihood-estimation","display_name":"maximum likelihood estimation","score":0.8040000200271606},{"id":"https://openalex.org/keywords/most-probable-number","display_name":"most probable number","score":0.8730000257492065},{"id":"https://openalex.org/keywords/serial-dilution","display_name":"serial dilution","score":0.890999972820282},{"id":"https://openalex.org/keywords/growth-plate","display_name":"growth plate","score":0.49399998784065247},{"id":"https://openalex.org/keywords/poisson-distribution","display_name":"Poisson distribution","score":0.7129999995231628},{"id":"https://openalex.org/keywords/truncated-poisson-distribution","display_name":"truncated Poisson distribution","score":0.925000011920929},{"id":"https://openalex.org/keywords/error-bounds","display_name":"error bounds","score":0.6990000009536743},{"id":"https://openalex.org/keywords/bacterial-concentration","display_name":"bacterial concentration","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C185429906","wikidata":"https://www.wikidata.org/wiki/Q1130160","display_name":"Estimator","level":2,"score":0.6925985217094421},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.6339156627655029},{"id":"https://openalex.org/C49781872","wikidata":"https://www.wikidata.org/wiki/Q1045555","display_name":"Maximum likelihood","level":2,"score":0.5123816728591919},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.4356447756290436},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.35295653343200684},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.32282257080078125}],"mesh":[{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D015169","descriptor_name":"Colony Count, Microbial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016012","descriptor_name":"Poisson Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016013","descriptor_name":"Likelihood Functions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1128/spectrum.03946-23","doi":"https://doi.org/10.1128/spectrum.03946-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/spectrum.03946-23","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},{"id":"doi:10.1101/2023.05.18.541301","doi":"https://doi.org/10.1101/2023.05.18.541301","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.05.18.541301","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/05/29/2023.05.18.541301.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:11371269","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11371269","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiol Spectr","raw_type":"Text"},{"id":"pmid:39041814","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39041814","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology spectrum","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:0509344d904a471ea3da9ff49cf1ba39","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/0509344d904a471ea3da9ff49cf1ba39","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Microbiology Spectrum, Vol 12, Iss 9 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1128/spectrum.03946-23","doi":"https://doi.org/10.1128/spectrum.03946-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/spectrum.03946-23","pdf_url":null,"source":{"id":"https://openalex.org/S2764766708","display_name":"Microbiology Spectrum","issn_l":"2165-0497","issn":["2165-0497"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology Spectrum","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2132649348","display_name":"Modeling Sources of Variation in Interaction Networks Using a C. Elegans Microbiome Model","funder_award_id":"2014173","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306164","display_name":"Simons Foundation","ror":"https://ror.org/01cmst727"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W108945167","https://openalex.org/W631307220","https://openalex.org/W1507153296","https://openalex.org/W1526127239","https://openalex.org/W1547960773","https://openalex.org/W1553793542","https://openalex.org/W1557517307","https://openalex.org/W1569706723","https://openalex.org/W1586957091","https://openalex.org/W1658446649","https://openalex.org/W1692079094","https://openalex.org/W1854458960","https://openalex.org/W1924308243","https://openalex.org/W1945277959","https://openalex.org/W1964271812","https://openalex.org/W1970597031","https://openalex.org/W1982263515","https://openalex.org/W1983628124","https://openalex.org/W2002974037","https://openalex.org/W2006818005","https://openalex.org/W2008034064","https://openalex.org/W2008255403","https://openalex.org/W2008701887","https://openalex.org/W2020965769","https://openalex.org/W2028006400","https://openalex.org/W2029348027","https://openalex.org/W2043314270","https://openalex.org/W2063984832","https://openalex.org/W2067716370","https://openalex.org/W2072723793","https://openalex.org/W2072916612","https://openalex.org/W2073389192","https://openalex.org/W2074938420","https://openalex.org/W2079258766","https://openalex.org/W2092348049","https://openalex.org/W2093443755","https://openalex.org/W2096353907","https://openalex.org/W2100218708","https://openalex.org/W2107975574","https://openalex.org/W2124566025","https://openalex.org/W2170343590","https://openalex.org/W2185119698","https://openalex.org/W2290266545","https://openalex.org/W2318357371","https://openalex.org/W2327274075","https://openalex.org/W2416114075","https://openalex.org/W2587508995","https://openalex.org/W2885775116","https://openalex.org/W2913110404","https://openalex.org/W2950265898","https://openalex.org/W3012610922","https://openalex.org/W4233471163","https://openalex.org/W4235962806","https://openalex.org/W4242237425","https://openalex.org/W4298439982","https://openalex.org/W4299997335"],"related_works":["https://openalex.org/W2043314270","https://openalex.org/W3115433794","https://openalex.org/W2067716370","https://openalex.org/W2104027579","https://openalex.org/W2034729887","https://openalex.org/W3012610922","https://openalex.org/W2103948255","https://openalex.org/W1991635596","https://openalex.org/W2011285864","https://openalex.org/W2215727874"],"abstract_inverted_index":{"Measuring":[0],"the":[1,82,120,123,129,139,175,213,277,306],"abundance":[2,248],"of":[3,39,84,96,122,146,170,212,215,244,249,264,272,296],"microbes":[4,216,250],"in":[5,50,217,305],"a":[6,9,13,71,87,109,147,218,225,242,253],"sample":[7,219],"is":[8,220],"common":[10,56,229],"procedure":[11],"with":[12,224],"long":[14,226],"history,":[15],"but":[16],"best":[17],"practices":[18],"are":[19,28],"not":[20],"well-conserved":[21],"across":[22,300],"microbiological":[23],"\ufb01elds.":[24],"Serial":[25],"dilution":[26,89],"methods":[27,57,186,245],"commonly":[29],"used":[30],"to":[31,35,45,58,118,138,151,158,260,293],"dilute":[32],"bacterial":[33,47],"cultures":[34],"produce":[36],"countable":[37],"numbers":[38],"colonies,":[40],"and":[41,75,165,177,202,251],"from":[42,128,235],"these":[43,94,113,210],"counts,":[44,173],"infer":[46],"concentrations":[48],"measured":[49],"colony-forming":[51,273],"units":[52,274],"(CFUs).":[53],"The":[54],"most":[55,124],"generate":[59],"data":[60,97,279],"for":[61,133,209,246,282,291],"CFU":[62,284],"point":[63,184],"estimates":[64,271],"involve":[65],"plating":[66],"bacteria":[67],"on":[68],"(or":[69],"in)":[70],"solid":[72],"growth":[73,140],"medium":[74],"counting":[76,81],"their":[77,196,262],"resulting":[78],"colonies":[79],"or":[80],"number":[83,126,214],"tubes":[85,131],"at":[86,162],"given":[88],"that":[90],"have":[91,98],"growth.":[92],"Traditionally,":[93],"types":[95],"been":[99],"analyzed":[100],"separately":[101],"using":[102,188,276],"different":[103,163,236,256],"analytic":[104],"methods.":[105,180,286],"Here,":[106],"we":[107,166,194,288],"build":[108],"direct":[110],"correspondence":[111],"between":[112,255],"approaches,":[114],"which":[115,134,258],"allows":[116,259],"one":[117],"extend":[119,261],"use":[121],"probable":[125],"method":[127],"liquid":[130],"experiments,":[132],"it":[135],"was":[136],"developed,":[137],"plates":[141],"by":[142],"viewing":[143],"colony-sized":[144],"patches":[145],"plate":[148],"as":[149,232],"equivalent":[150],"individual":[152],"tubes.":[153],"We":[154,181,204,240],"also":[155],"discuss":[156,195],"how":[157,292],"combine":[159,294],"measurements":[160,295],"taken":[161,299],"dilutions,":[164,301],"review":[167],"several":[168,303],"ways":[169],"analyzing":[171],"colony":[172,297],"including":[174],"Poisson":[176,179],"truncated":[178],"test":[182],"all":[183,192],"estimate":[185],"computationally":[187],"simulated":[189],"data.":[190],"For":[191],"methods,":[193,257],"relevant":[197],"error":[198],"bounds,":[199],"assumptions,":[200],"strengths,":[201],"weaknesses.":[203],"provide":[205,241,289],"an":[206,221],"online":[207],"calculator":[208],"estimators.Estimation":[211],"important":[222],"problem":[223],"history.":[227],"Yet":[228],"practices,":[230],"such":[231],"combining":[233],"results":[234],"measurements,":[237],"remain":[238],"sub-optimal.":[239],"comparison":[243],"estimating":[247],"detail":[252],"mapping":[254,267],"range":[263],"applicability.":[265],"This":[266],"enables":[268],"higher":[269],"precision":[270],"(CFUs)":[275],"same":[278],"already":[280],"collected":[281],"traditional":[283],"estimation":[285],"Furthermore,":[287],"recommendations":[290],"counts":[298],"correcting":[302],"misconceptions":[304],"literature.":[307]},"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2024-07-24T00:00:00"}