{"id":"https://openalex.org/W4400895694","doi":"https://doi.org/10.1093/cei/uxae065","title":"Investigating immune profile by CyTOF in patients with eosinophilic esophagitis after treatment with orodispersible budesonide","display_name":"Investigating immune profile by CyTOF in patients with eosinophilic esophagitis after treatment with orodispersible budesonide","publication_year":2024,"publication_date":"2024-07-22","ids":{"openalex":"https://openalex.org/W4400895694","doi":"https://doi.org/10.1093/cei/uxae065","pmid":"https://pubmed.ncbi.nlm.nih.gov/39034635","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11404122"},"language":"en","primary_location":{"id":"doi:10.1093/cei/uxae065","doi":"https://doi.org/10.1093/cei/uxae065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/cei/uxae065","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/cei/uxae065","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102771172","display_name":"John E. Plate","orcid":"https://orcid.org/0009-0009-1988-2561","observed_orcids":["https://orcid.org/0009-0009-1988-2561"]},"institutions":[{"id":"https://openalex.org/I4210095705","display_name":"Region V\u00e4stra G\u00f6taland","ror":"https://ror.org/00a4x6777","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210095705"]},{"id":"https://openalex.org/I4210103371","display_name":"NU Hospital Group","ror":"https://ror.org/01fa85441","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210103371"]},{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"John Plate","raw_affiliation_strings":["Department of Otorhinolaryngology Head and Neck Surgery, Region V\u00e4stra G\u00f6taland, NU-Hospital Group , Trollh\u00e4ttan , Sweden","Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden"],"raw_orcid":"https://orcid.org/0009-0009-1988-2561","affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology Head and Neck Surgery, Region V\u00e4stra G\u00f6taland, NU-Hospital Group , Trollh\u00e4ttan , Sweden","institution_ids":["https://openalex.org/I4210095705","https://openalex.org/I4210103371"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059543283","display_name":"Sofie Albinsson","orcid":"https://orcid.org/0000-0003-2038-4286","observed_orcids":["https://orcid.org/0000-0003-2038-4286"]},"institutions":[{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sofie Albinsson H\u00f6gberg","raw_affiliation_strings":["Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden"],"raw_orcid":"https://orcid.org/0000-0003-2038-4286","affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013081719","display_name":"Hardis Rabe","orcid":"https://orcid.org/0000-0003-1184-6135","observed_orcids":["https://orcid.org/0000-0003-1184-6135"]},"institutions":[{"id":"https://openalex.org/I2800664555","display_name":"RISE Research Institutes of Sweden","ror":"https://ror.org/03nnxqz81","country_code":"SE","type":"other","lineage":["https://openalex.org/I2800664555"]},{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hardis Rabe","raw_affiliation_strings":["Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","RISE Research Institutes of Sweden, Bioscience and Materials , Gothenburg , Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","institution_ids":["https://openalex.org/I881427289"]},{"raw_affiliation_string":"RISE Research Institutes of Sweden, Bioscience and Materials , Gothenburg , Sweden","institution_ids":["https://openalex.org/I2800664555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027932114","display_name":"Helen M. Larsson","orcid":"https://orcid.org/0000-0001-5950-3356","observed_orcids":["https://orcid.org/0000-0001-5950-3356"]},"institutions":[{"id":"https://openalex.org/I4210095705","display_name":"Region V\u00e4stra G\u00f6taland","ror":"https://ror.org/00a4x6777","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210095705"]},{"id":"https://openalex.org/I4210103371","display_name":"NU Hospital Group","ror":"https://ror.org/01fa85441","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I4210103371"]},{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Helen Larsson","raw_affiliation_strings":["Department of Otorhinolaryngology Head and Neck Surgery, Region V\u00e4stra G\u00f6taland, NU-Hospital Group , Trollh\u00e4ttan , Sweden","Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology Head and Neck Surgery, Region V\u00e4stra G\u00f6taland, NU-Hospital Group , Trollh\u00e4ttan , Sweden","institution_ids":["https://openalex.org/I4210095705","https://openalex.org/I4210103371"]},{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","institution_ids":["https://openalex.org/I881427289"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065215558","display_name":"Christine Lingblom","orcid":"https://orcid.org/0000-0003-1284-6911","observed_orcids":["https://orcid.org/0000-0003-1284-6911"]},"institutions":[{"id":"https://openalex.org/I2801112325","display_name":"Sahlgrenska University Hospital","ror":"https://ror.org/04vgqjj36","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I2801112325"]},{"id":"https://openalex.org/I881427289","display_name":"University of Gothenburg","ror":"https://ror.org/01tm6cn81","country_code":"SE","type":"education","lineage":["https://openalex.org/I881427289"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Christine Lingblom","raw_affiliation_strings":["Department of Clinical Microbiology, Sahlgrenska University Hospital , Gothenburg , Sweden","Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden"],"raw_orcid":"https://orcid.org/0000-0003-1284-6911","affiliations":[{"raw_affiliation_string":"Department of Clinical Microbiology, Sahlgrenska University Hospital , Gothenburg , Sweden","institution_ids":["https://openalex.org/I2801112325"]},{"raw_affiliation_string":"Institute of Biomedicine, Department of Infectious Diseases, The Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden","institution_ids":["https://openalex.org/I881427289"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5065215558"],"corresponding_institution_ids":["https://openalex.org/I2801112325","https://openalex.org/I881427289"],"apc_list":{"value":3039,"currency":"GBP","value_usd":3884},"apc_paid":{"value":3039,"currency":"GBP","value_usd":3884},"fwci":0.2564,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49458949,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"218","issue":"1","first_page":"1","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eosinophilic-esophagitis","display_name":"eosinophilic esophagitis","score":1.0},{"id":"https://openalex.org/keywords/immunological-profile","display_name":"immunological profile","score":0.652999997138977},{"id":"https://openalex.org/keywords/eosinophils","display_name":"eosinophils","score":0.8289999961853027},{"id":"https://openalex.org/keywords/effector-memory-t-cells","display_name":"effector memory T cells","score":0.9129999876022339},{"id":"https://openalex.org/keywords/galectin-10","display_name":"galectin-10","score":0.8989999890327454},{"id":"https://openalex.org/keywords/type-2-inflammation","display_name":"type 2 inflammation","score":0.7170000076293945},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.7310000061988831},{"id":"https://openalex.org/keywords/blood-based-biomarkers","display_name":"blood-based biomarkers","score":0.7960000038146973},{"id":"https://openalex.org/keywords/esophageal-histology","display_name":"esophageal histology","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2781065132","wikidata":"https://www.wikidata.org/wiki/Q2057356","display_name":"Eosinophilic esophagitis","level":3,"score":0.8858805894851685},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8010576367378235},{"id":"https://openalex.org/C2776136866","wikidata":"https://www.wikidata.org/wiki/Q422212","display_name":"Budesonide","level":3,"score":0.770126461982727},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6520592570304871},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6109330058097839},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5614705085754395},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.4834512174129486},{"id":"https://openalex.org/C2777819096","wikidata":"https://www.wikidata.org/wiki/Q173710","display_name":"Esophagus","level":2,"score":0.4805772304534912},{"id":"https://openalex.org/C2779929431","wikidata":"https://www.wikidata.org/wiki/Q2948600","display_name":"High-power field","level":3,"score":0.4695834517478943},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4319435954093933},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40098804235458374},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.3867080509662628},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3224303722381592},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.19604837894439697}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004947","descriptor_name":"Esophagus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004947","descriptor_name":"Esophagus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019819","descriptor_name":"Budesonide","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019819","descriptor_name":"Budesonide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057765","descriptor_name":"Eosinophilic Esophagitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D057765","descriptor_name":"Eosinophilic Esophagitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/cei/uxae065","doi":"https://doi.org/10.1093/cei/uxae065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/cei/uxae065","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11404122","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11404122","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11404122/pdf/uxae065.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmid:39034635","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39034635","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"},{"id":"pmh:oai:DiVA.org:ri-75656","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-75656","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/cei/uxae065","doi":"https://doi.org/10.1093/cei/uxae065","is_oa":true,"landing_page_url":"https://doi.org/10.1093/cei/uxae065","pdf_url":null,"source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309605","display_name":"V\u00e4stra G\u00f6talandsregionen","ror":"https://ror.org/00a4x6777"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400895694.pdf","grobid_xml":"https://content.openalex.org/works/W4400895694.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1482505181","https://openalex.org/W1588650347","https://openalex.org/W1897577349","https://openalex.org/W1979320478","https://openalex.org/W1979850061","https://openalex.org/W1982729887","https://openalex.org/W1994763008","https://openalex.org/W1999229101","https://openalex.org/W1999272877","https://openalex.org/W2000741917","https://openalex.org/W2037836883","https://openalex.org/W2064326663","https://openalex.org/W2071617661","https://openalex.org/W2078475980","https://openalex.org/W2126302947","https://openalex.org/W2136248567","https://openalex.org/W2159553688","https://openalex.org/W2162528206","https://openalex.org/W2164161262","https://openalex.org/W2257010553","https://openalex.org/W2340128484","https://openalex.org/W2550188758","https://openalex.org/W2581091354","https://openalex.org/W2616331564","https://openalex.org/W2741654639","https://openalex.org/W2925319593","https://openalex.org/W2926346269","https://openalex.org/W2929224310","https://openalex.org/W3021183730","https://openalex.org/W3032341729","https://openalex.org/W3045151909","https://openalex.org/W3094199572","https://openalex.org/W3127200525","https://openalex.org/W3135344603","https://openalex.org/W3180437170","https://openalex.org/W3192570677","https://openalex.org/W4206942658","https://openalex.org/W4239894904","https://openalex.org/W4245181308","https://openalex.org/W4321367344","https://openalex.org/W4383873226","https://openalex.org/W6628946233"],"related_works":["https://openalex.org/W1897577349","https://openalex.org/W3032341729","https://openalex.org/W4393984991","https://openalex.org/W4413034854","https://openalex.org/W6977136751","https://openalex.org/W3093502755","https://openalex.org/W2466463186","https://openalex.org/W7204010297","https://openalex.org/W409429872","https://openalex.org/W7203986494"],"abstract_inverted_index":{"Eosinophilic":[0],"esophagitis":[1],"(EoE)":[2],"is":[3,35,230],"a":[4,86,213,231],"chronic":[5],"Th2-mediated":[6],"inflammatory":[7],"disease":[8],"of":[9,44,124,151,166,194],"the":[10,30,33,80,135,149,182,195,200,207],"esophagus":[11,34],"driven":[12],"by":[13,37,71],"dietary":[14],"or":[15],"inhalant":[16],"allergens":[17],"which":[18],"if":[19],"left":[20],"untreated,":[21],"leads":[22],"to":[23,134,242,245],"fibrosis":[24],"and":[25,46,57,63,98,108,111,156,203,222,228],"poor":[26],"esophageal":[27,174],"function.":[28],"Although":[29],"inflammation":[31],"in":[32,148,173,199,206,217],"dominated":[36],"eosinophils,":[38],"there":[39],"are":[40],"also":[41],"elevated":[42],"levels":[43,123,165],"T":[45,127],"B":[47],"cells.":[48],"Blood":[49],"samples":[50],"from":[51,176],"ten":[52],"patients":[53,118,153,196,218],"with":[54,60,85,95,119,131,170,189,219,225],"EoE":[55,120,152,177,220],"before":[56,154,221],"after":[58,129,162,187,223],"treatment":[59,130,155,188,224],"orodispersible":[61,132,190,226],"budesonide":[62,133,227],"10":[64],"healthy":[65,139],"controls":[66],"were":[67,146,160,185],"compared":[68],"using":[69],"cytometry":[70],"time-of-flight.":[72],"An":[73],"antibody":[74],"panel":[75],"was":[76,93,103],"designed":[77],"that":[78,117,238],"covers":[79],"major":[81],"immunological":[82],"cell":[83],"populations":[84],"particular":[87],"focus":[88],"on":[89],"eosinophils.":[90],"The":[91],"data":[92],"analyzed":[94],"multivariate":[96],"methods":[97],"cluster":[99],"analysis.":[100],"Correlation":[101],"analysis":[102,115],"done":[104],"between":[105],"immune":[106,215,236],"markers":[107],"endoscopic,":[109],"histological,":[110],"symptomatologic":[112],"assessments.":[113],"Our":[114],"revealed":[116],"had":[121,197],"lower":[122],"effector":[125],"memory":[126],"cells":[128],"same":[136],"level":[137],"as":[138],"subjects.":[140],"In":[141,179],"addition,":[142],"more":[143,157],"suppressive":[144],"eosinophils":[145,159,168,184],"present":[147,161],"circulation":[150],"immature":[158],"treatment.":[163,246],"Furthermore,":[164],"galectin-10+":[167],"correlated":[169],"histological":[171,201],"findings":[172],"tissue":[175],"patients.":[178],"all":[180],"patients,":[181],"peak":[183],"decreased":[186],"budesonide.":[191],"Intriguingly,":[192],"90%":[193],"remission":[198],"assessment":[202],"50%":[204],"improved":[205],"endoscopic":[208],"assessment.":[209],"This":[210],"study":[211],"reports":[212],"detailed":[214],"profile":[216],"it":[229],"step":[232],"toward":[233],"finding":[234],"blood-based":[235],"parameters":[237],"could":[239],"be":[240],"useful":[241],"monitor":[243],"response":[244]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-07-23T00:00:00"}
