{"id":"https://openalex.org/W4400826111","doi":"https://doi.org/10.1016/j.jid.2024.06.612","title":"596 Uncovering minimal pathways in melanoma initiation","display_name":"596 Uncovering minimal pathways in melanoma initiation","publication_year":2024,"publication_date":"2024-07-19","ids":{"openalex":"https://openalex.org/W4400826111","doi":"https://doi.org/10.1016/j.jid.2024.06.612"},"language":"en","primary_location":{"id":"doi:10.1016/j.jid.2024.06.612","doi":"https://doi.org/10.1016/j.jid.2024.06.612","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jid.2024.06.612","pdf_url":"http://www.jidonline.org/article/S0022202X24010613/pdf","source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jidonline.org/article/S0022202X24010613/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"H. Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Xiao","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045715345","display_name":"Jessica Shiu","orcid":"https://orcid.org/0000-0002-2264-8372","observed_orcids":["https://orcid.org/0000-0002-2264-8372"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Shiu","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032200694","display_name":"C. Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Chen","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Wu","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072894189","display_name":"Peijie Zhou","orcid":"https://orcid.org/0000-0002-4585-2923","observed_orcids":["https://orcid.org/0000-0002-4585-2923"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Zhou","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030125759","display_name":"Arthur D. Lander","orcid":"https://orcid.org/0000-0002-4380-5525","observed_orcids":["https://orcid.org/0000-0002-4380-5525"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Lander","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078269386","display_name":"Anand K. Ganesan","orcid":"https://orcid.org/0000-0003-4944-9274","observed_orcids":["https://orcid.org/0000-0003-4944-9274"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Ganesan","raw_affiliation_strings":["University of California, Irvine, Irvine, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Irvine, Irvine, California, United States","institution_ids":["https://openalex.org/I204250578"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204250578"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0823202,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"144","issue":"8","first_page":"S104","last_page":"S104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cutaneous-melanoma","display_name":"cutaneous melanoma","score":0.9279999732971191},{"id":"https://openalex.org/keywords/melanoma-initiation","display_name":"melanoma initiation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/nras","display_name":"NRAS","score":0.6069999933242798},{"id":"https://openalex.org/keywords/pten-loss","display_name":"PTEN loss","score":0.6800000071525574},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.8429999947547913},{"id":"https://openalex.org/keywords/pigmentation-genes","display_name":"pigmentation genes","score":0.6570000052452087},{"id":"https://openalex.org/keywords/mouse-tumor-model","display_name":"mouse tumor model","score":0.6399999856948853},{"id":"https://openalex.org/keywords/tumor-heterogeneity","display_name":"tumor heterogeneity","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.5393405556678772},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4134783148765564},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3578260838985443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32245850563049316},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3165619671344757}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jid.2024.06.612","doi":"https://doi.org/10.1016/j.jid.2024.06.612","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jid.2024.06.612","pdf_url":"http://www.jidonline.org/article/S0022202X24010613/pdf","source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jid.2024.06.612","doi":"https://doi.org/10.1016/j.jid.2024.06.612","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jid.2024.06.612","pdf_url":"http://www.jidonline.org/article/S0022202X24010613/pdf","source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400826111.pdf","grobid_xml":"https://content.openalex.org/works/W4400826111.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4411668766","https://openalex.org/W819200961","https://openalex.org/W1970195561","https://openalex.org/W2047432020","https://openalex.org/W2093924594","https://openalex.org/W1971571835","https://openalex.org/W2318725744","https://openalex.org/W2028752124","https://openalex.org/W7148809330","https://openalex.org/W2740959424"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2024-07-20T00:00:00"}