{"id":"https://openalex.org/W4400616684","doi":"https://doi.org/10.21608/ejprs.2024.365335","title":"Use of Lyophilized Growth Factors Foam in Chronic Ulcers","display_name":"Use of Lyophilized Growth Factors Foam in Chronic Ulcers","publication_year":2024,"publication_date":"2024-07-01","ids":{"openalex":"https://openalex.org/W4400616684","doi":"https://doi.org/10.21608/ejprs.2024.365335"},"language":"en","primary_location":{"id":"doi:10.21608/ejprs.2024.365335","doi":"https://doi.org/10.21608/ejprs.2024.365335","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21608/ejprs.2024.365335","pdf_url":null,"source":{"id":"https://openalex.org/S4210204133","display_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","issn_l":"1110-0044","issn":["1110-0044","2974-4709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4323237894","host_organization_name":"Egypts Presidential Specialized Council for Education and Scientific Research","host_organization_lineage":["https://openalex.org/P4323237894"],"host_organization_lineage_names":["Egypts Presidential Specialized Council for Education and Scientific Research"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://dx.doi.org/10.21608/ejprs.2024.365335","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113288361","display_name":"Adel Mabrouk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Adel Mabrouk","raw_affiliation_strings":["The Department of Plastic, Burn and Maxillofacial Surgery, Faculty of Medicine, Ain Shams University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Plastic, Burn and Maxillofacial Surgery, Faculty of Medicine, Ain Shams University","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hossam M Fahmy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Hossam M Fahmy","raw_affiliation_strings":["The Department of Laboratory & Transfusion Medicine, Faculty of Medicine, Ain Shams University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Laboratory & Transfusion Medicine, Faculty of Medicine, Ain Shams University","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040777821","display_name":"Amr Reda Mabrouk","orcid":"https://orcid.org/0009-0000-6513-1077","observed_orcids":["https://orcid.org/0009-0000-6513-1077"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Amr Mabrouk","raw_affiliation_strings":["The Department of Plastic, Burn and Maxillofacial Surgery, Faculty of Medicine, Ain Shams University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Plastic, Burn and Maxillofacial Surgery, Faculty of Medicine, Ain Shams University","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103232288","display_name":"Mai Raafat Hammad","orcid":"https://orcid.org/0000-0002-0999-3040","observed_orcids":["https://orcid.org/0000-0002-0999-3040"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mai Raafat Hammad","raw_affiliation_strings":["The Department of Plastic, Burn, and Maxillofacial Surgery, \nFaculty of Medicine, Ain Shams University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Plastic, Burn, and Maxillofacial Surgery, \nFaculty of Medicine, Ain Shams University","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063332406","display_name":"Mohamed Samir Badawy","orcid":"https://orcid.org/0000-0002-7543-1679","observed_orcids":["https://orcid.org/0000-0002-7543-1679"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed Samir Badawy","raw_affiliation_strings":["The Department of Plastic, Burn and Maxillofacial Surgery, \nFaculty of Medicine, Ain Shams University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Department of Plastic, Burn and Maxillofacial Surgery, \nFaculty of Medicine, Ain Shams University","institution_ids":["https://openalex.org/I107720978"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I107720978"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"48","issue":"3","first_page":"211","last_page":"216"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-ulcers","display_name":"chronic ulcers","score":0.8420000076293945},{"id":"https://openalex.org/keywords/leg-ulcers","display_name":"leg ulcers","score":0.9290000200271606},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.9269999861717224},{"id":"https://openalex.org/keywords/platelet-rich-plasma","display_name":"platelet-rich plasma","score":0.9240000247955322},{"id":"https://openalex.org/keywords/growth-factor-delivery-systems","display_name":"growth factor delivery systems","score":0.7760000228881836},{"id":"https://openalex.org/keywords/topical-wound-dressing","display_name":"topical wound dressing","score":0.8069999814033508},{"id":"https://openalex.org/keywords/ulcer-size-reduction","display_name":"ulcer size reduction","score":0.9229999780654907}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32527899742126465}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.21608/ejprs.2024.365335","doi":"https://doi.org/10.21608/ejprs.2024.365335","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21608/ejprs.2024.365335","pdf_url":null,"source":{"id":"https://openalex.org/S4210204133","display_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","issn_l":"1110-0044","issn":["1110-0044","2974-4709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4323237894","host_organization_name":"Egypts Presidential Specialized Council for Education and Scientific Research","host_organization_lineage":["https://openalex.org/P4323237894"],"host_organization_lineage_names":["Egypts Presidential Specialized Council for Education and Scientific Research"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:0eb78de27321406f8aa17555a8c96012","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0eb78de27321406f8aa17555a8c96012","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Egyptian Journal of Plastic and Reconstructive Surgery, Vol 48, Iss 3, Pp 211-216 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.21608/ejprs.2024.365335","doi":"https://doi.org/10.21608/ejprs.2024.365335","is_oa":true,"landing_page_url":"http://dx.doi.org/10.21608/ejprs.2024.365335","pdf_url":null,"source":{"id":"https://openalex.org/S4210204133","display_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","issn_l":"1110-0044","issn":["1110-0044","2974-4709"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4323237894","host_organization_name":"Egypts Presidential Specialized Council for Education and Scientific Research","host_organization_lineage":["https://openalex.org/P4323237894"],"host_organization_lineage_names":["Egypts Presidential Specialized Council for Education and Scientific Research"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Egyptian Journal of Plastic and Reconstructive Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4391719388","https://openalex.org/W4416775781","https://openalex.org/W2994684949","https://openalex.org/W1965167103","https://openalex.org/W2888310681","https://openalex.org/W4241430630","https://openalex.org/W4416790632","https://openalex.org/W3189816802","https://openalex.org/W2782243154","https://openalex.org/W4391227626"],"abstract_inverted_index":{"Background:":[0],"Treatment":[1],"of":[2,14,31,39,64,77,104,108,119],"chronic":[3,32],"ulcers":[4,33,100,118,176],"involves":[5],"addressingthe":[6],"underlying":[7],"cause":[8],"and":[9,50],"interventions":[10],"to":[11,74,114,123],"improvethe":[12],"process":[13],"healing":[15,30,171],"such":[16,42],"as":[17,34,43,88,121,177],"autologous":[18],"platelet-rich":[19],"plasma.Platelet-rich":[20],"plasma":[21],"has":[22],"been":[23,59,68,136],"extensively":[24],"studied":[25],"for":[26,95,101,138,144,159],"its":[27,166],"potentialin":[28],"promoting":[29,169],"it":[35],"contains":[36],"ahigh":[37],"concentration":[38],"growth":[40,48,54,65,93,132],"factors":[41,133],"platelet":[44,79],"derivedgrowth":[45],"factor,":[46],"epithelial":[47],"factor":[49,55],"fibroblast":[51],"growthfactor.":[52],"Advanced":[53],"delivery":[56],"systems":[57],"have":[58,67,135],"developedto":[60],"prolong":[61],"the":[62,102,160],"bio-activity":[63],"factors.LGF":[66],"developed":[69,137],"by":[70],"a":[71,89,127,153,178],"patented":[72],"method":[73],"overcomethe":[75],"discrepancies":[76],"conventional":[78,124],"rich":[80],"plasma.Objective:":[81],"In":[82],"this":[83],"study,":[84,150],"we":[85],"present":[86],"LGFoam":[87,161],"topicalagent":[90],"containing":[91],"Lyophilized":[92],"factors,":[94],"use":[96,167],"in":[97,168,172],"chroniclower":[98],"limb":[99,117],"purpose":[103],"improving":[105],"healing.Methodology:":[106],"Comparison":[107],"ulcer":[109,157],"size":[110,158],"between":[111],"LGFoamtopically":[112],"applied":[113],"non-healing":[115,175],"lower":[116],"variousetiologies,":[120],"opposed":[122],"dressing":[125],"with":[126],"30-dayfollow-up":[128],"period.Conclusion:":[129],"Several":[130],"advanced":[131],"deliverysystems":[134],"topical":[139],"use.":[140],"However,":[141],"conflictingevidence":[142],"exists":[143],"their":[145],"efficacy,":[146],"warranting":[147],"furtherresearch.In":[148],"our":[149],"there":[151],"was":[152],"statistically":[154],"significant":[155],"decreasein":[156],"group,":[162],"encouraging":[163],"future":[164],"studiesinto":[165],"wound":[170],"general,":[173],"especiallychronic":[174],"problematic":[179],"entity.":[180]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-07-15T00:00:00"}
