{"id":"https://openalex.org/W4400599744","doi":"https://doi.org/10.3390/dna4030014","title":"Comparative Analysis of Five Forensic PCR Kits in Duplets","display_name":"Comparative Analysis of Five Forensic PCR Kits in Duplets","publication_year":2024,"publication_date":"2024-07-11","ids":{"openalex":"https://openalex.org/W4400599744","doi":"https://doi.org/10.3390/dna4030014"},"language":"en","primary_location":{"id":"doi:10.3390/dna4030014","doi":"https://doi.org/10.3390/dna4030014","is_oa":true,"landing_page_url":"https://doi.org/10.3390/dna4030014","pdf_url":null,"source":{"id":"https://openalex.org/S4210187882","display_name":"DNA","issn_l":"2673-8856","issn":["2673-8856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DNA","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/dna4030014","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093879710","display_name":"Tam\u00e1s Cseppent\u0151","orcid":"https://orcid.org/0009-0009-1267-4604","observed_orcids":["https://orcid.org/0009-0009-1267-4604"]},"institutions":[{"id":"https://openalex.org/I4210145592","display_name":"B\u0171n\u00fcgyi Szak\u00e9rt\u0151i \u00e9s Kutat\u00f3int\u00e9zet","ror":"https://ror.org/04fv4f289","country_code":"HU","type":"government","lineage":["https://openalex.org/I4210145592"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Tam\u00e1s Cseppent\u0151","raw_affiliation_strings":["Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary","institution_ids":["https://openalex.org/I4210145592"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099299825","display_name":"Norbert G. Valis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145592","display_name":"B\u0171n\u00fcgyi Szak\u00e9rt\u0151i \u00e9s Kutat\u00f3int\u00e9zet","ror":"https://ror.org/04fv4f289","country_code":"HU","type":"government","lineage":["https://openalex.org/I4210145592"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Norbert G. Valis","raw_affiliation_strings":["Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary","institution_ids":["https://openalex.org/I4210145592"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065116514","display_name":"Guszt\u00e1v B\u00e1r\u00e1ny","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145592","display_name":"B\u0171n\u00fcgyi Szak\u00e9rt\u0151i \u00e9s Kutat\u00f3int\u00e9zet","ror":"https://ror.org/04fv4f289","country_code":"HU","type":"government","lineage":["https://openalex.org/I4210145592"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Guszt\u00e1v B\u00e1r\u00e1ny","raw_affiliation_strings":["Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary","institution_ids":["https://openalex.org/I4210145592"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099299824","display_name":"B\u00e1lint Megadja","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B\u00e1lint Megadja","raw_affiliation_strings":["Department of Surgery, Szent Margit Hospital Budapest, B\u00e9csi u. 132, H-1032 Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Szent Margit Hospital Budapest, B\u00e9csi u. 132, H-1032 Budapest, Hungary","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Attila Heinrich","orcid":"https://orcid.org/0009-0001-9229-1508","observed_orcids":["https://orcid.org/0009-0001-9229-1508"]},"institutions":[{"id":"https://openalex.org/I4210145592","display_name":"B\u0171n\u00fcgyi Szak\u00e9rt\u0151i \u00e9s Kutat\u00f3int\u00e9zet","ror":"https://ror.org/04fv4f289","country_code":"HU","type":"government","lineage":["https://openalex.org/I4210145592"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Attila Heinrich","raw_affiliation_strings":["Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary"],"raw_orcid":"https://orcid.org/0009-0001-9229-1508","affiliations":[{"raw_affiliation_string":"Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary","institution_ids":["https://openalex.org/I4210145592"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055911882","display_name":"N\u00f3ra M. Magonyi","orcid":"https://orcid.org/0009-0007-9521-4368","observed_orcids":["https://orcid.org/0009-0007-9521-4368"]},"institutions":[{"id":"https://openalex.org/I4210145592","display_name":"B\u0171n\u00fcgyi Szak\u00e9rt\u0151i \u00e9s Kutat\u00f3int\u00e9zet","ror":"https://ror.org/04fv4f289","country_code":"HU","type":"government","lineage":["https://openalex.org/I4210145592"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"N\u00f3ra M. Magonyi","raw_affiliation_strings":["Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary"],"raw_orcid":"https://orcid.org/0009-0007-9521-4368","affiliations":[{"raw_affiliation_string":"Department of Genetics, Hungarian Institute for Forensic Sciences, Mosonyi u. 9, H-1087 Budapest, Hungary","institution_ids":["https://openalex.org/I4210145592"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5093879710"],"corresponding_institution_ids":["https://openalex.org/I4210145592"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1137},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1137},"fwci":0.1966,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.38257565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"4","issue":"3","first_page":"212","last_page":"220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiplex-pcr","display_name":"multiplex PCR","score":0.6639999747276306},{"id":"https://openalex.org/keywords/short-tandem-repeat-markers","display_name":"short tandem repeat loci","score":0.765999972820282},{"id":"https://openalex.org/keywords/low-copy-number-dna","display_name":"low copy number DNA","score":0.9710000157356262},{"id":"https://openalex.org/keywords/allele-dropout","display_name":"allele dropout","score":0.7459999918937683},{"id":"https://openalex.org/keywords/likelihood-ratios","display_name":"likelihood ratios","score":0.8450000286102295},{"id":"https://openalex.org/keywords/composite-profiles","display_name":"composite profiles","score":0.8149999976158142},{"id":"https://openalex.org/keywords/globalfiler","display_name":"GlobalFiler","score":0.9380000233650208}],"concepts":[{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.5301868319511414},{"id":"https://openalex.org/C140505726","wikidata":"https://www.wikidata.org/wiki/Q495304","display_name":"Forensic science","level":2,"score":0.48869588971138},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4292870759963989},{"id":"https://openalex.org/C2911193946","wikidata":"https://www.wikidata.org/wiki/Q476697","display_name":"Forensic genetics","level":5,"score":0.4256322979927063},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3655179738998413},{"id":"https://openalex.org/C61320498","wikidata":"https://www.wikidata.org/wiki/Q265193","display_name":"Microsatellite","level":4,"score":0.29410648345947266},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29254990816116333},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.20233160257339478},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08443939685821533}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/dna4030014","doi":"https://doi.org/10.3390/dna4030014","is_oa":true,"landing_page_url":"https://doi.org/10.3390/dna4030014","pdf_url":null,"source":{"id":"https://openalex.org/S4210187882","display_name":"DNA","issn_l":"2673-8856","issn":["2673-8856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DNA","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:046c7ca7ff4e481cb8b6fbdccd125774","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/046c7ca7ff4e481cb8b6fbdccd125774","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"DNA, Vol 4, Iss 3, Pp 212-220 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/dna4030014","doi":"https://doi.org/10.3390/dna4030014","is_oa":true,"landing_page_url":"https://doi.org/10.3390/dna4030014","pdf_url":null,"source":{"id":"https://openalex.org/S4210187882","display_name":"DNA","issn_l":"2673-8856","issn":["2673-8856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DNA","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1966490810","https://openalex.org/W2005447216","https://openalex.org/W2020942802","https://openalex.org/W2037279163","https://openalex.org/W2106359530","https://openalex.org/W2111517251","https://openalex.org/W2123665956","https://openalex.org/W2209919369","https://openalex.org/W2429349951","https://openalex.org/W2595797439","https://openalex.org/W2757550644","https://openalex.org/W2791890676","https://openalex.org/W2795343770","https://openalex.org/W2989606614","https://openalex.org/W4283329261","https://openalex.org/W4296044477","https://openalex.org/W4391601215","https://openalex.org/W4399867927"],"related_works":["https://openalex.org/W4401994814","https://openalex.org/W2739053071","https://openalex.org/W7135283897","https://openalex.org/W4296044477","https://openalex.org/W2018665803","https://openalex.org/W7220286350","https://openalex.org/W2467615581","https://openalex.org/W4414581412","https://openalex.org/W3036551064","https://openalex.org/W3158470837"],"abstract_inverted_index":{"In":[0,182],"forensic":[1,41],"DNA":[2,55],"laboratories,":[3],"it":[4],"is":[5,186],"important":[6],"to":[7,23,33,150,188],"conduct":[8],"internal":[9],"validations":[10],"of":[11,16,39,111,130,137,146,155,170,192,199],"the":[12,40,71,79,89,100,112,124,134,138,143,151,153,165,168,171,178,190,193],"commercially":[13],"available":[14],"kits":[15,42,63,113,176],"short":[17],"tandem":[18],"repeat":[19],"(STR)":[20],"loci":[21],"and":[22,27,47,99,133,160,174],"investigate":[24],"their":[25,48],"individual":[26],"combined":[28,144],"effectiveness.":[29],"This":[30],"study":[31,185],"aims":[32],"report":[34],"on":[35],"a":[36],"comparative":[37],"investigation":[38],"used":[43,58],"in":[44,50],"our":[45,184],"laboratory":[46],"combinations":[49],"analysing":[51],"low-copy-number":[52],"(LCN)":[53],"human":[54],"samples.":[56],"We":[57],"five":[59],"partly":[60],"overlapping":[61],"multiplex":[62],"with":[64],"different":[65,69,200],"marker":[66],"configurations":[67],"from":[68],"manufacturers:":[70],"NGM":[72,77,172],"SelectTM":[73],"PCR":[74],"Amplification":[75,81],"Kit,":[76],"DetectTM,":[78],"GlobalFilerTM":[80,175],"Kit":[82,104],"(Applied":[83],"BiosystemTM,":[84],"Foster":[85],"City,":[86],"CA,":[87],"USA),":[88],"PowerPlex\u00ae":[90,156],"Fusion":[91,157],"6C":[92,158],"System":[93,159],"(Promega":[94],"Co.,":[95],"Madison,":[96],"WI,":[97],"USA)":[98],"Investigator\u00ae":[101,161],"24plex":[102,162],"QS":[103,163],"(Qiagen":[105],"GmbH,":[106],"Hilden,":[107],"Germany).":[108],"The":[109],"efficacy":[110],"was":[114],"scrutinised":[115],"by":[116,142],"specific":[117],"criteria,":[118],"such":[119],"as":[120],"allelic":[121],"dropout":[122],"rate,":[123],"individually":[125],"calculated":[126],"Likelihood":[127],"Ratio":[128],"(LR)":[129],"consensus":[131],"profiles":[132,145],"LR":[135,180],"value":[136],"composite":[139],"profile":[140],"produced":[141,164],"two":[147],"kits.":[148],"According":[149],"results,":[152],"pairing":[154,169],"lowest,":[166],"while":[167],"DetectTM":[173],"provided":[177],"highest":[179],"value.":[181],"summary,":[183],"meant":[187],"aid":[189],"selection":[191],"optimal":[194],"kit":[195],"combination":[196],"for":[197],"samples":[198],"qualities.":[201]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2024-07-13T00:00:00"}