{"id":"https://openalex.org/W4400580484","doi":"https://doi.org/10.1186/s12903-024-04520-2","title":"Impact of concentrated growth factor (CGF) injection on acceleration of orthodontic tooth movement in rabbits","display_name":"Impact of concentrated growth factor (CGF) injection on acceleration of orthodontic tooth movement in rabbits","publication_year":2024,"publication_date":"2024-07-12","ids":{"openalex":"https://openalex.org/W4400580484","doi":"https://doi.org/10.1186/s12903-024-04520-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/38997695","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11245833"},"language":"en","primary_location":{"id":"doi:10.1186/s12903-024-04520-2","doi":"https://doi.org/10.1186/s12903-024-04520-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-024-04520-2","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12903-024-04520-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093455001","display_name":"Safa B. Alawy","orcid":"https://orcid.org/0000-0002-2761-1923","observed_orcids":["https://orcid.org/0000-0002-2761-1923"]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Safa B. Alawy","raw_affiliation_strings":["Orthodontics, Faculty of Dentistry, Tanta University, Tanta, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthodontics, Faculty of Dentistry, Tanta University, Tanta, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104423091","display_name":"Mona Al Ahmady El Meligy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mona Al Ahmady El Meligy","raw_affiliation_strings":["Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology Faculty of Dentistry, Tanta University, Tanta, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-4464-8653","affiliations":[{"raw_affiliation_string":"Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology Faculty of Dentistry, Tanta University, Tanta, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111349824","display_name":"eman mohamed salem","orcid":"https://orcid.org/0000-0003-4464-8653","observed_orcids":["https://orcid.org/0000-0003-4464-8653"]},"institutions":[{"id":"https://openalex.org/I146977602","display_name":"Pharos University in Alexandria","ror":"https://ror.org/04cgmbd24","country_code":"EG","type":"education","lineage":["https://openalex.org/I146977602"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Eman M. Salem","raw_affiliation_strings":["Oral Biology, Faculty of Dentistry, Pharos University in Alexandria, P. O. Box 37, Sidi Gaber, Alexandria, Egypt. Eman.salem@pua.edu.eg","Oral Biology, Faculty of Dentistry, Pharos University in Alexandria, P. O. Box 37, Sidi Gaber, Alexandria, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oral Biology, Faculty of Dentistry, Pharos University in Alexandria, P. O. Box 37, Sidi Gaber, Alexandria, Egypt. Eman.salem@pua.edu.eg","institution_ids":["https://openalex.org/I146977602"]},{"raw_affiliation_string":"Oral Biology, Faculty of Dentistry, Pharos University in Alexandria, P. O. Box 37, Sidi Gaber, Alexandria, Egypt","institution_ids":["https://openalex.org/I146977602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067821570","display_name":"Wafaa Yahia Alghonemy","orcid":"https://orcid.org/0000-0002-0452-2565","observed_orcids":["https://orcid.org/0000-0002-0452-2565"]},"institutions":[{"id":"https://openalex.org/I153687341","display_name":"Zarqa University","ror":"https://ror.org/01wf1es90","country_code":"JO","type":"education","lineage":["https://openalex.org/I153687341"]},{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG","JO"],"is_corresponding":false,"raw_author_name":"Wafaa Yahia Alghonemy","raw_affiliation_strings":["Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, 13110, Jordan","Oral Biology Department, Faculty of Dentistry, Tanta University, Tanta, 31527, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, 13110, Jordan","institution_ids":["https://openalex.org/I153687341"]},{"raw_affiliation_string":"Oral Biology Department, Faculty of Dentistry, Tanta University, Tanta, 31527, Egypt","institution_ids":["https://openalex.org/I21376657"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5111349824"],"corresponding_institution_ids":["https://openalex.org/I146977602"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":2.6854,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.87710135,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"24","issue":"1","first_page":"783","last_page":"783"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12367","display_name":"Dental Trauma and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/concentrated-growth-factor","display_name":"concentrated growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/orthodontic-tooth-movement","display_name":"orthodontic tooth movement","score":0.9879999756813049},{"id":"https://openalex.org/keywords/mesialization","display_name":"mesialization","score":0.7480000257492065},{"id":"https://openalex.org/keywords/maxillary-first-molar","display_name":"maxillary first molar","score":0.9010000228881836},{"id":"https://openalex.org/keywords/submucosal-injection","display_name":"submucosal injection","score":0.8820000290870667},{"id":"https://openalex.org/keywords/periodontal-ligament","display_name":"periodontal ligament","score":0.8140000104904175},{"id":"https://openalex.org/keywords/bone-resorption","display_name":"bone resorption","score":0.8389999866485596},{"id":"https://openalex.org/keywords/cementoblasts","display_name":"cementoblasts","score":0.6779999732971191},{"id":"https://openalex.org/keywords/osteoblasts","display_name":"osteoblasts","score":0.996999979019165},{"id":"https://openalex.org/keywords/fibroblasts","display_name":"fibroblasts","score":0.9150000214576721},{"id":"https://openalex.org/keywords/rabbit-model","display_name":"rabbit model","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8874307870864868},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.7778916358947754},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.6632406711578369},{"id":"https://openalex.org/C2780639617","wikidata":"https://www.wikidata.org/wiki/Q6516972","display_name":"Quadrant (abdomen)","level":2,"score":0.646605372428894},{"id":"https://openalex.org/C2778636310","wikidata":"https://www.wikidata.org/wiki/Q504033","display_name":"Oral and maxillofacial surgery","level":2,"score":0.5675874352455139},{"id":"https://openalex.org/C41868710","wikidata":"https://www.wikidata.org/wiki/Q540092","display_name":"Periodontal fiber","level":2,"score":0.5027425289154053},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.46773892641067505},{"id":"https://openalex.org/C146562846","wikidata":"https://www.wikidata.org/wiki/Q96649518","display_name":"Resorption","level":2,"score":0.4223650395870209},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15090641379356384},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07521894574165344}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001862","descriptor_name":"Bone Resorption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008437","descriptor_name":"Maxilla","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008963","descriptor_name":"Molar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014087","descriptor_name":"Tooth Movement Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D036341","descriptor_name":"Intercellular Signaling Peptides and Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12903-024-04520-2","doi":"https://doi.org/10.1186/s12903-024-04520-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-024-04520-2","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11245833","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11245833","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11245833/pdf/12903_2024_Article_4520.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"Text"},{"id":"pmid:38997695","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38997695","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC oral health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a39fdbe266aa4ae1924bb619385f990e","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a39fdbe266aa4ae1924bb619385f990e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Oral Health, Vol 24, Iss 1, Pp 1-9 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12903-024-04520-2","doi":"https://doi.org/10.1186/s12903-024-04520-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-024-04520-2","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400580484.pdf","grobid_xml":"https://content.openalex.org/works/W4400580484.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W173908020","https://openalex.org/W1526378667","https://openalex.org/W1545832524","https://openalex.org/W1576729112","https://openalex.org/W1807192274","https://openalex.org/W1961393689","https://openalex.org/W1967654423","https://openalex.org/W1988998621","https://openalex.org/W1995130128","https://openalex.org/W1997209485","https://openalex.org/W2004836604","https://openalex.org/W2006297354","https://openalex.org/W2007233978","https://openalex.org/W2018292027","https://openalex.org/W2034155482","https://openalex.org/W2035249720","https://openalex.org/W2048202061","https://openalex.org/W2052243139","https://openalex.org/W2053797170","https://openalex.org/W2075489098","https://openalex.org/W2081579820","https://openalex.org/W2088580357","https://openalex.org/W2088907820","https://openalex.org/W2096315654","https://openalex.org/W2096455093","https://openalex.org/W2099743160","https://openalex.org/W2104165505","https://openalex.org/W2108162594","https://openalex.org/W2111155031","https://openalex.org/W2129140427","https://openalex.org/W2129358933","https://openalex.org/W2150851241","https://openalex.org/W2154688513","https://openalex.org/W2163688233","https://openalex.org/W2170582387","https://openalex.org/W2524382081","https://openalex.org/W2551260288","https://openalex.org/W2562193069","https://openalex.org/W2606009676","https://openalex.org/W2806411965","https://openalex.org/W2915025758","https://openalex.org/W2948841445","https://openalex.org/W3187238766","https://openalex.org/W3195238129","https://openalex.org/W4200338959","https://openalex.org/W4220776920","https://openalex.org/W4311141018","https://openalex.org/W4362640966"],"related_works":["https://openalex.org/W404323924","https://openalex.org/W7096791724","https://openalex.org/W2380116752","https://openalex.org/W2354075540","https://openalex.org/W2352717572","https://openalex.org/W4214905868","https://openalex.org/W2298067645","https://openalex.org/W2361299811","https://openalex.org/W2387919934","https://openalex.org/W3151297749"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,63,71,82,97],"present":[2],"study":[3,72],"aimed":[4],"to":[5,113,216],"assess":[6],"how":[7],"a":[8,28,69,94],"concentrated":[9],"growth":[10],"factor":[11],"(CGF)":[12],"injection":[13],"affects":[14],"the":[15,35,48,54,106,120,132,139,153,156,168,174,180,183,192,200,208,214],"rate":[16],"of":[17,34,53,84,145],"orthodontic":[18,32,219],"tooth":[19,85,127,220],"movement":[20,86,128,221],"in":[21,58,131,138],"rabbits.":[22],"METHODS:":[23],"This":[24],"experimental":[25,133],"investigation":[26],"employed":[27],"split-mouth":[29],"configuration.":[30],"Before":[31],"mesialization":[33],"maxillary":[36,55,103,107],"first":[37,56,108,169,193],"molars,":[38,109],"CGF":[39,157,184,212],"was":[40,66,87,129],"prepared":[41],"and":[42,50,79,101,122,142,162,171,188,203],"administered":[43],"using":[44,93],"submucosal":[45],"injections":[46],"on":[47,118,152,179],"buccal":[49],"palatal":[51],"sides":[52,134,137],"molars":[57],"one":[59],"randomly":[60],"assigned":[61],"quadrant.":[62],"opposite":[64],"quadrant":[65],"used":[67],"as":[68],"control.":[70],"examined":[73],"four":[74],"time":[75],"points:1,":[76],"2,":[77],"3,":[78],"4":[80],"weeks.":[81,177],"measurement":[83],"conducted":[88],"at":[89],"each":[90],"follow-up":[91,146],"point":[92],"digital":[95],"caliper.":[96],"rabbits":[98],"were":[99,110],"euthanized,":[100],"their":[102],"segments,":[104],"specifically":[105],"studied":[111],"histologically":[112],"identify":[114],"any":[115],"alterations":[116],"occurring":[117],"both":[119],"tension":[121,181],"compression":[123,154],"sides.":[124],"RESULTS:":[125],"Significant":[126],"observed":[130],"versus":[135],"control":[136],"second,":[140],"third,":[141],"fourth":[143,209],"week":[144,170,194,202],"periods":[147],"(p":[148],"\u2264":[149],"0.05).":[150],"Histologically,":[151],"side,":[155,182],"group":[158,185],"showed":[159],"bone":[160],"resorption":[161],"periodontal":[163],"ligament":[164],"active":[165],"reactions":[166],"from":[167,191,199],"continued":[172,206],"throughout":[173],"next":[175],"three":[176],"Also,":[178],"depicted":[186],"cementoblastic":[187],"osteoblastic":[189],"activities":[190,198,205],"followed":[195],"by":[196],"fibroblastic":[197],"second":[201],"all":[204],"till":[207],"week.":[210],"CONCLUSIONS:":[211],"has":[213],"potential":[215],"effectively":[217],"enhance":[218],"without":[222],"adverse":[223],"clinical":[224],"or":[225],"histological":[226],"effects.":[227]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-07-13T00:00:00"}