{"id":"https://openalex.org/W4400510264","doi":"https://doi.org/10.1002/art.42929","title":"Air Pollution, Genetic Susceptibility, and Risk of Incident Systemic Lupus Erythematosus: A Prospective Cohort Study","display_name":"Air Pollution, Genetic Susceptibility, and Risk of Incident Systemic Lupus Erythematosus: A Prospective Cohort Study","publication_year":2024,"publication_date":"2024-07-10","ids":{"openalex":"https://openalex.org/W4400510264","doi":"https://doi.org/10.1002/art.42929","pmid":"https://pubmed.ncbi.nlm.nih.gov/38982844"},"language":"en","primary_location":{"id":"doi:10.1002/art.42929","doi":"https://doi.org/10.1002/art.42929","is_oa":true,"landing_page_url":"https://doi.org/10.1002/art.42929","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42929","source":{"id":"https://openalex.org/S4210186158","display_name":"Arthritis & Rheumatology","issn_l":"2326-5191","issn":["2326-5191","2326-5205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42929","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052196335","display_name":"Meiqi Xing","orcid":"https://orcid.org/0009-0002-9797-169X","observed_orcids":["https://orcid.org/0009-0002-9797-169X"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meiqi Xing","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":"https://orcid.org/0009-0002-9797-169X","affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082442574","display_name":"Yudiyang Ma","orcid":"https://orcid.org/0000-0001-6032-3862","observed_orcids":["https://orcid.org/0000-0001-6032-3862"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yudiyang Ma","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077299913","display_name":"Feipeng Cui","orcid":"https://orcid.org/0009-0000-4291-4028","observed_orcids":["https://orcid.org/0009-0000-4291-4028"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feipeng Cui","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049187659","display_name":"Dankang Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dankang Li","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111318473","display_name":"Jianing Wang","orcid":"https://orcid.org/0009-0002-5203-8767","observed_orcids":["https://orcid.org/0009-0002-5203-8767"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianing Wang","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011684209","display_name":"Linxi Tang","orcid":"https://orcid.org/0009-0006-8537-1143","observed_orcids":["https://orcid.org/0009-0006-8537-1143","https://orcid.org/0009-0009-4549-3674"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linxi Tang","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005824885","display_name":"Lei Zheng","orcid":"https://orcid.org/0000-0003-0131-3474","observed_orcids":["https://orcid.org/0000-0003-0131-3474"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Zheng","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100644503","display_name":"Jian Yang","orcid":"https://orcid.org/0000-0002-1391-1482","observed_orcids":["https://orcid.org/0000-0002-1391-1482"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]},{"id":"https://openalex.org/I4210152080","display_name":"Yichang Central People's Hospital","ror":"https://ror.org/04cr34a11","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152080"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Yang","raw_affiliation_strings":["The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital, Hubei Key Laboratory of Ischemic Cardiovascular Disease, and Hubei Provincial Clinical Research Center for Ischemic Cardiovascular Disease  Yichang China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital, Hubei Key Laboratory of Ischemic Cardiovascular Disease, and Hubei Provincial Clinical Research Center for Ischemic Cardiovascular Disease  Yichang China","institution_ids":["https://openalex.org/I161350542","https://openalex.org/I4210152080"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102067050","display_name":"Yaohua Tian","orcid":"https://orcid.org/0000-0002-9853-6991","observed_orcids":["https://orcid.org/0000-0002-9853-6991"]},"institutions":[{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yaohua Tian","raw_affiliation_strings":["Huazhong University of Science and Technology  Wuhan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Huazhong University of Science and Technology  Wuhan China","institution_ids":["https://openalex.org/I47720641"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100644503","https://openalex.org/A5102067050"],"corresponding_institution_ids":["https://openalex.org/I161350542","https://openalex.org/I4210152080","https://openalex.org/I47720641"],"apc_list":{"value":4940,"currency":"USD","value_usd":4940},"apc_paid":{"value":4940,"currency":"USD","value_usd":4940},"fwci":4.1008,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.9585318,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"76","issue":"10","first_page":"1530","last_page":"1537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.8452000021934509,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.8452000021934509,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.14419999718666077,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.996999979019165},{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.9819999933242798},{"id":"https://openalex.org/keywords/pm2-5","display_name":"PM2.5","score":0.9539999961853027},{"id":"https://openalex.org/keywords/pm10","display_name":"PM10","score":0.9919999837875366},{"id":"https://openalex.org/keywords/nitrogen-dioxide","display_name":"nitrogen dioxide","score":1.0},{"id":"https://openalex.org/keywords/nitrogen-oxides","display_name":"nitrogen oxides","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.8870000243186951},{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.8870000243186951},{"id":"https://openalex.org/keywords/environmental-risk-factors","display_name":"environmental risk factors","score":0.6740000247955322},{"id":"https://openalex.org/keywords/disease-incidence","display_name":"disease incidence","score":0.5139999985694885},{"id":"https://openalex.org/keywords/uk-biobank","display_name":"UK Biobank","score":0.7670000195503235},{"id":"https://openalex.org/keywords/land-use-regression","display_name":"land use regression","score":0.8960000276565552},{"id":"https://openalex.org/keywords/multiplicative-interaction","display_name":"multiplicative interaction","score":0.5809999704360962},{"id":"https://openalex.org/keywords/autoimmune-disease-susceptibility","display_name":"autoimmune disease susceptibility","score":0.44200000166893005},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.33399999141693115},{"id":"https://openalex.org/keywords/alcohol-consumption","display_name":"alcohol consumption","score":0.6539999842643738},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.6955846548080444},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6542521119117737},{"id":"https://openalex.org/C82685317","wikidata":"https://www.wikidata.org/wiki/Q19829510","display_name":"Pollutant","level":2,"score":0.5743371844291687},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5152192711830139},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5039545893669128},{"id":"https://openalex.org/C559116025","wikidata":"https://www.wikidata.org/wiki/Q131123","display_name":"Air pollution","level":2,"score":0.463113933801651},{"id":"https://openalex.org/C24245907","wikidata":"https://www.wikidata.org/wiki/Q498957","display_name":"Particulates","level":2,"score":0.4585859477519989},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.4524279534816742},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4209684729576111},{"id":"https://openalex.org/C2987853052","wikidata":"https://www.wikidata.org/wiki/Q131123","display_name":"Air pollutants","level":3,"score":0.4167667627334595},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.411375492811203},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25610095262527466},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1376015841960907},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.05816221237182617}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000393","descriptor_name":"Air Pollutants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000397","descriptor_name":"Air Pollution","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004781","descriptor_name":"Environmental Exposure","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009585","descriptor_name":"Nitrogen Dioxide","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D009585","descriptor_name":"Nitrogen Dioxide","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009589","descriptor_name":"Nitrogen Oxides","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D009589","descriptor_name":"Nitrogen Oxides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052638","descriptor_name":"Particulate Matter","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/art.42929","doi":"https://doi.org/10.1002/art.42929","is_oa":true,"landing_page_url":"https://doi.org/10.1002/art.42929","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42929","source":{"id":"https://openalex.org/S4210186158","display_name":"Arthritis & Rheumatology","issn_l":"2326-5191","issn":["2326-5191","2326-5205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & Rheumatology","raw_type":"journal-article"},{"id":"pmid:38982844","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38982844","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & rheumatology (Hoboken, N.J.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/art.42929","doi":"https://doi.org/10.1002/art.42929","is_oa":true,"landing_page_url":"https://doi.org/10.1002/art.42929","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.42929","source":{"id":"https://openalex.org/S4210186158","display_name":"Arthritis & Rheumatology","issn_l":"2326-5191","issn":["2326-5191","2326-5205"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arthritis & Rheumatology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4711465333","display_name":null,"funder_award_id":"YCJJ20230228","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400510264.pdf","grobid_xml":"https://content.openalex.org/works/W4400510264.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1998561407","https://openalex.org/W2057320665","https://openalex.org/W2066544083","https://openalex.org/W2067484351","https://openalex.org/W2071833767","https://openalex.org/W2072651272","https://openalex.org/W2082704080","https://openalex.org/W2100129058","https://openalex.org/W2106553167","https://openalex.org/W2145738328","https://openalex.org/W2159860161","https://openalex.org/W2486559230","https://openalex.org/W2509437552","https://openalex.org/W2747001950","https://openalex.org/W2762501827","https://openalex.org/W2766878940","https://openalex.org/W2769628177","https://openalex.org/W2783117893","https://openalex.org/W2795416164","https://openalex.org/W2799624238","https://openalex.org/W2889764344","https://openalex.org/W2912642129","https://openalex.org/W2920182969","https://openalex.org/W2935310973","https://openalex.org/W2980738033","https://openalex.org/W3003943436","https://openalex.org/W3011875420","https://openalex.org/W3101728843","https://openalex.org/W3127296780","https://openalex.org/W3179821770","https://openalex.org/W3189785095","https://openalex.org/W3213938066","https://openalex.org/W4211051788","https://openalex.org/W4296635715","https://openalex.org/W4307343800","https://openalex.org/W4307669964","https://openalex.org/W4318263662","https://openalex.org/W4402597735"],"related_works":["https://openalex.org/W4405617837","https://openalex.org/W2920182969","https://openalex.org/W4412513716","https://openalex.org/W4307343800","https://openalex.org/W4245907675","https://openalex.org/W4296635715","https://openalex.org/W3101728843","https://openalex.org/W7154617112","https://openalex.org/W4415471602","https://openalex.org/W4385631563"],"abstract_inverted_index":{"Objective":[0],"There":[1,146,243],"are":[2],"few":[3],"existing":[4],"studies":[5],"that":[6],"investigate":[7],"the":[8,118,158,201,266],"risk":[9,46,110,125,194,203,213,267],"of":[10,44,53,63,102,123,132,143,204,268],"systemic":[11],"lupus":[12],"erythematosus":[13],"(SLE)":[14],"associated":[15],"with":[16,69,135,191,208,210],"long\u2010term":[17,29],"exposure":[18,30,153,199,218,255],"to":[19,25,31,99,256],"air":[20,32,48,64,103,127,151,197,216,257],"pollutants.":[21,49,128],"This":[22],"study":[23],"aimed":[24],"explore":[26,100],"associations":[27,149],"between":[28,150,249],"pollutants":[33,65,104,258],"and":[34,37,41,47,83,105,120,126,154,174,186,195,214,237,251,262],"incident":[35,106,155,205],"SLE":[36,136,206],"further":[38,116],"evaluate":[39],"interactions":[40,119],"joint":[42,121],"effects":[43,122],"genetic":[45,124,193,212],"Methods":[50],"A":[51,130],"total":[52,131],"459,815":[54],"participants":[55,190],"were":[56,87,137,147,162],"included":[57],"from":[58],"UK":[59],"Biobank.":[60],"The":[61,108],"concentrations":[62],"(fine":[66],"particulate":[67,74],"matter":[68,75],"diameter":[70,76],"\u22642.5":[71],"\u03bcm":[72,78],"[PM2.5],":[73],"\u226410":[77],"[PM10],":[79],"nitrogen":[80,84],"dioxide":[81],"[NO2],":[82],"oxides":[85],"[NOx])":[86],"estimated":[88],"by":[89],"land\u2010use":[90],"regression":[91],"model.":[92],"We":[93],"applied":[94],"Cox":[95],"proportional":[96],"hazards":[97],"model":[98],"linkages":[101],"SLE.":[107,270],"polygenic":[109],"score":[111],"(PRS)":[112],"was":[113,244],"used":[114],"for":[115,177],"assessing":[117],"Results":[129],"399":[133],"patients":[134],"identified":[138],"during":[139],"a":[140,245],"median":[141],"follow\u2010up":[142],"11.77":[144],"years.":[145],"positive":[148],"pollutant":[152],"SLE,":[156],"as":[157],"adjusted":[159],"hazard":[160,220],"ratios":[161],"1.18":[163],"(95%":[164],"confidence":[165],"interval":[166],"[95%":[167,224,229,234,240],"CI]":[168],"1.06\u20131.32),":[169],"1.23":[170],"(1.10\u20131.39),":[171],"1.27":[172],"(1.14\u20131.41),":[173],"1.13":[175],"(1.03\u20131.23)":[176],"each":[178],"interquartile":[179],"range":[180],"increase":[181,265],"in":[182],"PM2.5,":[183,222],"PM10,":[184,227,260],"NO2,":[185,232,261],"NOx,":[187,238],"respectively.":[188],"Moreover,":[189],"high":[192,196],"pollution":[198,217],"had":[200],"highest":[202],"compared":[207],"those":[209],"low":[211,215],"(adjusted":[219],"ratio:":[221],"4.16":[223],"CI":[225,230,235,241],"2.67\u20136.49];":[226],"5.31":[228],"3.30,\u20138.55];":[231],"5.61":[233],"3.45\u20139.13];":[236],"4.80":[239],"3.00\u20137.66]).":[242],"significant":[246],"multiplicative":[247],"interaction":[248],"NO2":[250],"PRS.":[252],"Conclusion":[253],"Long\u2010term":[254],"(PM2.5,":[259],"NOx)":[263],"may":[264],"developing":[269]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-07-11T00:00:00"}