{"id":"https://openalex.org/W4400405802","doi":"https://doi.org/10.1186/s12967-024-05452-9","title":"Synergistic effect of FOXM1 and BCL-2 inhibition in a preclinical treatment study on multiple myeloma","display_name":"Synergistic effect of FOXM1 and BCL-2 inhibition in a preclinical treatment study on multiple myeloma","publication_year":2024,"publication_date":"2024-07-08","ids":{"openalex":"https://openalex.org/W4400405802","doi":"https://doi.org/10.1186/s12967-024-05452-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/38977990","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11232139"},"language":"en","primary_location":{"id":"doi:10.1186/s12967-024-05452-9","doi":"https://doi.org/10.1186/s12967-024-05452-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-024-05452-9","pdf_url":"https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-024-05452-9","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-024-05452-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113432019","display_name":"Vivian Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310546135","display_name":"Froedtert Hospital","ror":"https://ror.org/01nhrc260","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1310546135"]},{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]},{"id":"https://openalex.org/I4392738256","display_name":"Medical College of Wisconsin Cancer Center","ror":"https://ror.org/0115fxs14","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I204308271","https://openalex.org/I4392738256"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vivian Zhou","raw_affiliation_strings":["Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA","institution_ids":["https://openalex.org/I1310546135","https://openalex.org/I204308271","https://openalex.org/I4392738256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028533513","display_name":"Manya Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310546135","display_name":"Froedtert Hospital","ror":"https://ror.org/01nhrc260","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1310546135"]},{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]},{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]},{"id":"https://openalex.org/I4392738256","display_name":"Medical College of Wisconsin Cancer Center","ror":"https://ror.org/0115fxs14","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I204308271","https://openalex.org/I4392738256"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Manya Yu","raw_affiliation_strings":["Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA","The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA","institution_ids":["https://openalex.org/I1310546135","https://openalex.org/I204308271","https://openalex.org/I4392738256"]},{"raw_affiliation_string":"The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China","institution_ids":["https://openalex.org/I134738993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001130000","display_name":"Jiaqi Fu","orcid":"https://orcid.org/0000-0003-0081-6133","observed_orcids":["https://orcid.org/0000-0003-0081-6133","https://orcid.org/0000-0001-5353-6835","https://orcid.org/0000-0002-6542-4344"]},"institutions":[{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaqi Fu","raw_affiliation_strings":["The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China","institution_ids":["https://openalex.org/I134738993"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Siegfried Janz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1310546135","display_name":"Froedtert Hospital","ror":"https://ror.org/01nhrc260","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1310546135"]},{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]},{"id":"https://openalex.org/I4392738256","display_name":"Medical College of Wisconsin Cancer Center","ror":"https://ror.org/0115fxs14","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I204308271","https://openalex.org/I4392738256"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Siegfried Janz","raw_affiliation_strings":["Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA. sjanz@mcw.edu","Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA. sjanz@mcw.edu","institution_ids":["https://openalex.org/I1310546135","https://openalex.org/I204308271"]},{"raw_affiliation_string":"Department of Medicine, Cancer Center-Froedtert Hospital, Medical College of Wisconsin, Milwaukee, WI, 53226, USA","institution_ids":["https://openalex.org/I1310546135","https://openalex.org/I204308271","https://openalex.org/I4392738256"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100371795","display_name":"Xing Cui","orcid":"https://orcid.org/0000-0002-8771-5898","observed_orcids":["https://orcid.org/0000-0002-8771-5898","https://orcid.org/0000-0001-6788-1920"]},"institutions":[{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]},{"id":"https://openalex.org/I4210159257","display_name":"Affiliated Hospital of Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/052q26725","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159257"]},{"id":"https://openalex.org/I4210161139","display_name":"Second Affiliated Hospital of Shandong University of TCM","ror":"https://ror.org/057bhmh42","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161139"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xing Cui","raw_affiliation_strings":["Department of Oncology and Hematology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China. cdz45@foxmail.com","Department of Oncology and Hematology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China"],"raw_orcid":"https://orcid.org/0000-0002-8771-5898","affiliations":[{"raw_affiliation_string":"Department of Oncology and Hematology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China. cdz45@foxmail.com","institution_ids":["https://openalex.org/I134738993","https://openalex.org/I4210159257","https://openalex.org/I4210161139"]},{"raw_affiliation_string":"Department of Oncology and Hematology, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong Province, PRC, China","institution_ids":["https://openalex.org/I4210159257","https://openalex.org/I4210161139"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100371795"],"corresponding_institution_ids":["https://openalex.org/I1310546135","https://openalex.org/I134738993","https://openalex.org/I204308271","https://openalex.org/I4210159257","https://openalex.org/I4210161139","https://openalex.org/I4392738256"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":{"value":3790,"currency":"USD","value_usd":3790},"fwci":1.2324,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.79793421,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"22","issue":"1","first_page":"638","last_page":"638"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12835","display_name":"FOXO transcription factor regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/foxm1","display_name":"FOXM1","score":0.972000002861023},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.8889999985694885},{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/drug-synergy","display_name":"drug synergy","score":0.652999997138977},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.8610000014305115}],"concepts":[{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.7969934344291687},{"id":"https://openalex.org/C170240278","wikidata":"https://www.wikidata.org/wiki/Q17928773","display_name":"FOXM1","level":4,"score":0.6150720119476318},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5327954888343811},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5204658508300781},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.45856842398643494},{"id":"https://openalex.org/C2780108899","wikidata":"https://www.wikidata.org/wiki/Q15366934","display_name":"Carfilzomib","level":4,"score":0.4178803265094757},{"id":"https://openalex.org/C2993043200","wikidata":"https://www.wikidata.org/wiki/Q7239206","display_name":"Preclinical research","level":2,"score":0.4108624756336212},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.39985743165016174},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3611697852611542},{"id":"https://openalex.org/C2777478702","wikidata":"https://www.wikidata.org/wiki/Q419319","display_name":"Bortezomib","level":3,"score":0.25041553378105164},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.18542030453681946},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.17821639776229858},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.07862710952758789}],"mesh":[{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000072278","descriptor_name":"Forkhead Box Protein M1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019253","descriptor_name":"Proto-Oncogene Proteins c-bcl-2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12967-024-05452-9","doi":"https://doi.org/10.1186/s12967-024-05452-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-024-05452-9","pdf_url":"https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-024-05452-9","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},{"id":"pmid:38977990","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38977990","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of translational medicine","raw_type":"Letter"},{"id":"pmh:oai:pubmedcentral.nih.gov:11232139","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11232139","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11232139/pdf/12967_2024_Article_5452.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Transl Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:72b1c27649fd48949b89486c51f36d61","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/72b1c27649fd48949b89486c51f36d61","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-4 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12967-024-05452-9","doi":"https://doi.org/10.1186/s12967-024-05452-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-024-05452-9","pdf_url":"https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/s12967-024-05452-9","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.5,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1786749919","display_name":null,"funder_award_id":"82274491","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2539979675","display_name":null,"funder_award_id":"82074348","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2890710920","display_name":null,"funder_award_id":"ZR2023LZL009","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"}],"funders":[{"id":"https://openalex.org/F4320312904","display_name":"Marshfield Clinic Research Institute","ror":"https://ror.org/04ky5a503"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324174","display_name":"Natural Science Foundation of Shandong Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400405802.pdf","grobid_xml":"https://content.openalex.org/works/W4400405802.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W4281896809","https://openalex.org/W4283835017","https://openalex.org/W4289526272","https://openalex.org/W4353094386","https://openalex.org/W4389219847"],"related_works":["https://openalex.org/W6977077231","https://openalex.org/W6958811108","https://openalex.org/W3157226362","https://openalex.org/W4389219847","https://openalex.org/W7120638042","https://openalex.org/W4414302658","https://openalex.org/W2604895301","https://openalex.org/W3009522834","https://openalex.org/W4408095370","https://openalex.org/W3126834826"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2024-07-09T00:00:00"}