{"id":"https://openalex.org/W4400301062","doi":"https://doi.org/10.2147/tcrm.s462317","title":"Analysis of Oxygen Concentration in the Oral Cavity During Intravenous Sedation with Intranasal Oxygen Administration for Dental Treatment","display_name":"Analysis of Oxygen Concentration in the Oral Cavity During Intravenous Sedation with Intranasal Oxygen Administration for Dental Treatment","publication_year":2024,"publication_date":"2024-07-01","ids":{"openalex":"https://openalex.org/W4400301062","doi":"https://doi.org/10.2147/tcrm.s462317","pmid":"https://pubmed.ncbi.nlm.nih.gov/38974311","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11227857"},"language":"en","primary_location":{"id":"doi:10.2147/tcrm.s462317","doi":"https://doi.org/10.2147/tcrm.s462317","is_oa":true,"landing_page_url":"https://doi.org/10.2147/tcrm.s462317","pdf_url":"https://www.dovepress.com/article/download/93999","source":{"id":"https://openalex.org/S204453222","display_name":"Therapeutics and Clinical Risk Management","issn_l":"1176-6336","issn":["1176-6336","1178-203X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutics and Clinical Risk Management","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/article/download/93999","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029978010","display_name":"Shota Abe","orcid":"https://orcid.org/0000-0003-4597-3327","observed_orcids":["https://orcid.org/0000-0003-4597-3327"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shota Abe","raw_affiliation_strings":["Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan"],"raw_orcid":"https://orcid.org/0000-0003-4597-3327","affiliations":[{"raw_affiliation_string":"Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072259561","display_name":"Akira Furuyama","orcid":"https://orcid.org/0000-0002-9657-6367","observed_orcids":["https://orcid.org/0000-0002-9657-6367"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Furuyama","raw_affiliation_strings":["Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015768611","display_name":"Kenji Ohsuga","orcid":"https://orcid.org/0000-0002-3117-9758","observed_orcids":["https://orcid.org/0000-0002-3117-9758"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Ohsuga","raw_affiliation_strings":["Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076351619","display_name":"Shinya Yamazaki","orcid":"https://orcid.org/0000-0002-9273-3927","observed_orcids":["https://orcid.org/0000-0002-9273-3927"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinya Yamazaki","raw_affiliation_strings":["Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan"],"raw_orcid":"https://orcid.org/0000-0002-9273-3927","affiliations":[{"raw_affiliation_string":"Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091569160","display_name":"Hiroyoshi Kawaai","orcid":"https://orcid.org/0000-0002-4718-0550","observed_orcids":["https://orcid.org/0000-0002-4718-0550"]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiroyoshi Kawaai","raw_affiliation_strings":["Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Anesthesiology, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]},{"raw_affiliation_string":"Department of Oral Physiology and Biochemistry, Ohu University, School of Dentistry, Koriyama City, Fukushima Prefecture, Japan","institution_ids":["https://openalex.org/I30181195"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5091569160"],"corresponding_institution_ids":["https://openalex.org/I30181195"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"Volume 20","issue":null,"first_page":"405","last_page":"412"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.7724999785423279,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.7724999785423279,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":0.21220000088214874,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intravenous-sedation","display_name":"intravenous sedation","score":0.9620000123977661},{"id":"https://openalex.org/keywords/propofol","display_name":"propofol","score":0.9929999709129333},{"id":"https://openalex.org/keywords/airway-burns","display_name":"airway burns","score":0.5920000076293945},{"id":"https://openalex.org/keywords/dental-sedation","display_name":"dental sedation","score":0.7379999756813049},{"id":"https://openalex.org/keywords/respiratory-depression","display_name":"respiratory depression","score":0.7039999961853027},{"id":"https://openalex.org/keywords/dental-implant-surgery","display_name":"dental implant surgery","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9492303133010864},{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.7712763547897339},{"id":"https://openalex.org/C2776814716","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Sedation","level":2,"score":0.7453082203865051},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6098470687866211},{"id":"https://openalex.org/C2908848679","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Intravenous sedation","level":3,"score":0.5608178973197937},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.5320988893508911},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5207564830780029},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3540262281894684},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3498610854148865},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.31530511379241943},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/tcrm.s462317","doi":"https://doi.org/10.2147/tcrm.s462317","is_oa":true,"landing_page_url":"https://doi.org/10.2147/tcrm.s462317","pdf_url":"https://www.dovepress.com/article/download/93999","source":{"id":"https://openalex.org/S204453222","display_name":"Therapeutics and Clinical Risk Management","issn_l":"1176-6336","issn":["1176-6336","1178-203X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutics and Clinical Risk Management","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11227857","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11227857","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11227857/pdf/tcrm-20-405.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ther Clin Risk Manag","raw_type":"Text"},{"id":"pmid:38974311","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38974311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutics and clinical risk management","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:4416ccea49f846349eda6efbd2347ac5","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/4416ccea49f846349eda6efbd2347ac5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Therapeutics and Clinical Risk Management, Vol Volume 20, Pp 405-412 (2024)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/93999","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/analysis-of-oxygen-concentration-in-the-oral-cavity-during-intravenous-peer-reviewed-fulltext-article-TCRM","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/tcrm.s462317","doi":"https://doi.org/10.2147/tcrm.s462317","is_oa":true,"landing_page_url":"https://doi.org/10.2147/tcrm.s462317","pdf_url":"https://www.dovepress.com/article/download/93999","source":{"id":"https://openalex.org/S204453222","display_name":"Therapeutics and Clinical Risk Management","issn_l":"1176-6336","issn":["1176-6336","1178-203X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutics and Clinical Risk Management","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400301062.pdf","grobid_xml":"https://content.openalex.org/works/W4400301062.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1522566596","https://openalex.org/W1604760603","https://openalex.org/W1972994324","https://openalex.org/W1994524440","https://openalex.org/W1998903818","https://openalex.org/W1999135149","https://openalex.org/W2024565910","https://openalex.org/W2025553461","https://openalex.org/W2048874497","https://openalex.org/W2075197281","https://openalex.org/W2082118004","https://openalex.org/W2083169522","https://openalex.org/W2134407926","https://openalex.org/W2325518908","https://openalex.org/W2340207005","https://openalex.org/W2462030017","https://openalex.org/W2966286619","https://openalex.org/W3013728472","https://openalex.org/W4361278968"],"related_works":["https://openalex.org/W4414896764","https://openalex.org/W2262004711","https://openalex.org/W1994525549","https://openalex.org/W2156446331","https://openalex.org/W6989268254","https://openalex.org/W7162947095","https://openalex.org/W2269992225","https://openalex.org/W4361278968","https://openalex.org/W3092933559","https://openalex.org/W4282941062"],"abstract_inverted_index":{"Purpose:":[0],"Intravenous":[1],"sedation":[2],"(IVS)":[3],"with":[4,16,18,47,86,117,182,250,291],"propofol":[5],"(PPF)":[6],"is":[7,60],"commonly":[8],"performed":[9,277],"in":[10,14,62,80,99,189,201,210,243,257,282],"dental":[11],"treatment,":[12],"particular":[13],"patients":[15],"dentophobia,":[17],"gag":[19],"reflex,":[20],"or":[21,110],"undergoing":[22],"implant":[23],"surgeries,":[24],"as":[25,261],"PPF":[26,36,48,87,120,161,251,292],"has":[27],"the":[28,63,72,78,100,148,176,183,187,190,199,202,211,214,219,225,239,244,255,258,262,280,283],"advantages":[29],"of":[30,103,123,132,178,213,221],"rapid":[31],"induction":[32],"and":[33,37,66,88,92,154,164,170,217,246,252,273,293],"recovery.":[34],"However,":[35],"other":[38],"intravenous":[39],"sedatives":[40],"may":[41,55],"cause":[42],"respiratory":[43],"depression.":[44],"Thus,":[45],"IVS":[46,85,249,290],"requires":[49],"oxygen":[50,59,81,89,135,253,294],"administration.":[51,90],"But":[52],"airway":[53],"burn":[54],"occur":[56],"when":[57,286],"high-concentration":[58],"stored":[61],"oral":[64,284],"cavity":[65,285],"catches":[67],"fire.":[68],"For":[69],"these":[70],"reasons,":[71],"present":[73],"study":[74],"aimed":[75],"to":[76,278],"elucidate":[77],"changes":[79],"concentration":[82],"(OC)":[83],"under":[84],"Patients":[91],"methods:":[93],"Nineteen":[94],"healthy":[95],"male":[96],"volunteers":[97],"participated":[98],"study.":[101],"None":[102],"them":[104],"had":[105],"missing":[106],"teeth,":[107],"nasal":[108,138],"congestion,":[109],"temporomandibular":[111],"joint":[112],"dysfunction.":[113],"They":[114],"were":[115,236],"sedated":[116],"a":[118,137,222],"continuous":[119],"infusion":[121,162],"dose":[122],"6":[124],"mg/kg/hr":[125],"for":[126],"25":[127],"min,":[128],"followed":[129],"by":[130],"administration":[131,268,295],"3":[133],"L/min":[134],"via":[136],"cannula.":[139],"The":[140],"OC":[141,188,200,215,226,256,281],"was":[142],"measured":[143],"at":[144,185,194,206],"two":[145,240],"sites,":[146],"namely,":[147],"median":[149,155],"maxillary":[150,156],"anterior":[151],"teeth":[152],"(MMAT)":[153],"soft":[157],"palate":[158],"(MMSP),":[159],"before":[160,216],"(baseline)":[163],"14,":[165],"15-18":[166],"(Term":[167,172],"1),":[168],"19,":[169],"20-23":[171],"2)":[173],"min":[174],"after":[175,218],"start":[177],"infusion.":[179],"Results:":[180],"Compared":[181],"values":[184],"baseline,":[186],"MMSP":[191],"significantly":[192,204],"increased":[193,205],"each":[195],"time":[196,241],"point,":[197],"whereas":[198],"MMAT":[203,245],"Term":[207],"2.":[208],"Furthermore,":[209],"comparison":[212],"use":[220],"mouth":[223],"prop,":[224],"exhibited":[227],"an":[228],"upward":[229],"trend,":[230],"but":[231],"no":[232],"statistically":[233],"significant":[234],"differences":[235],"observed":[237],"between":[238],"points":[242],"MMSP.":[247],"In":[248],"administration,":[254],"pharynx":[259],"increases":[260],"sedative":[263],"level":[264],"deepens.":[265],"Conclusion:":[266],"Oxygen":[267],"should":[269,275],"be":[270,276],"temporarily":[271],"discontinued,":[272],"suction":[274],"decrease":[279],"sparking":[287],"procedures":[288],"during":[289],"are":[296],"performed.":[297]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-07-05T00:00:00"}