{"id":"https://openalex.org/W4400260909","doi":"https://doi.org/10.1038/s41467-024-49852-3","title":"Environmental circadian disruption re-writes liver circadian proteomes","display_name":"Environmental circadian disruption re-writes liver circadian proteomes","publication_year":2024,"publication_date":"2024-07-01","ids":{"openalex":"https://openalex.org/W4400260909","doi":"https://doi.org/10.1038/s41467-024-49852-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/37693605","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10491124"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-024-49852-3","doi":"https://doi.org/10.1038/s41467-024-49852-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-49852-3","pdf_url":null,"source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1038/s41467-024-49852-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011552317","display_name":"Hao A. Duong","orcid":"https://orcid.org/0000-0002-2460-5915","observed_orcids":["https://orcid.org/0000-0002-2460-5915"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hao A. Duong","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA. hduong@msm.edu","Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA. hduong@msm.edu"],"raw_orcid":"https://orcid.org/0000-0002-2460-5915","affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA. hduong@msm.edu","institution_ids":["https://openalex.org/I6332465"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA. hduong@msm.edu","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029520164","display_name":"Kenkichi Baba","orcid":"https://orcid.org/0009-0007-2382-5231","observed_orcids":["https://orcid.org/0009-0007-2382-5231","https://orcid.org/0000-0002-7697-3170"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenkichi Baba","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057843180","display_name":"Jason P. DeBruyne","orcid":"https://orcid.org/0000-0001-9803-9568","observed_orcids":["https://orcid.org/0000-0001-9803-9568"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason P. DeBruyne","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":"https://orcid.org/0000-0001-9803-9568","affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085655452","display_name":"Alec J. Davidson","orcid":"https://orcid.org/0000-0003-4205-1968","observed_orcids":["https://orcid.org/0000-0003-4205-1968"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alec J. Davidson","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":"https://orcid.org/0000-0003-4205-1968","affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5096830099","display_name":"Christopher Ehlen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Ehlen","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":"https://orcid.org/0000-0003-3223-9262","affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008199496","display_name":"Michael D. Powell","orcid":"https://orcid.org/0000-0001-7698-4841","observed_orcids":["https://orcid.org/0000-0001-7698-4841"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Powell","raw_affiliation_strings":["Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087080862","display_name":"Gianluca Tosini","orcid":"https://orcid.org/0000-0003-3645-4533","observed_orcids":["https://orcid.org/0000-0003-3645-4533"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gianluca Tosini","raw_affiliation_strings":["Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA"],"raw_orcid":"https://orcid.org/0000-0003-3645-4533","affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]},{"raw_affiliation_string":"Department of Pharmacology and Toxicology, Morehouse School of Medicine, Atlanta, GA, 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5011552317"],"corresponding_institution_ids":["https://openalex.org/I6332465"],"apc_list":{"value":6790,"currency":"USD","value_usd":6790},"apc_paid":{"value":6790,"currency":"USD","value_usd":6790},"fwci":4.27,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.95760345,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"5537","last_page":"5537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circadian-clock","display_name":"circadian clock","score":0.8230000138282776},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.7620000243186951},{"id":"https://openalex.org/keywords/circadian-gene-expression","display_name":"circadian gene expression","score":0.8659999966621399},{"id":"https://openalex.org/keywords/shift-work","display_name":"shift work","score":0.8169999718666077},{"id":"https://openalex.org/keywords/jet-lag","display_name":"jet lag","score":0.9950000047683716},{"id":"https://openalex.org/keywords/post-translational-regulation","display_name":"post-translational regulation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/nuclear-proteome","display_name":"nuclear proteome","score":0.8059999942779541},{"id":"https://openalex.org/keywords/transcriptome","display_name":"transcriptome","score":0.777999997138977},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.8330000042915344},{"id":"https://openalex.org/keywords/rna-processing","display_name":"RNA processing","score":0.9459999799728394},{"id":"https://openalex.org/keywords/protein-localization","display_name":"protein localization","score":0.9890000224113464},{"id":"https://openalex.org/keywords/fat-metabolism","display_name":"fat metabolism","score":0.8410000205039978},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.9470000267028809}],"concepts":[{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.8996647596359253},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.8964723944664001},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.7804140448570251},{"id":"https://openalex.org/C38606739","wikidata":"https://www.wikidata.org/wiki/Q5121352","display_name":"Circadian clock","level":3,"score":0.6866165399551392},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6576073169708252},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38805556297302246},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3783424496650696},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33045244216918945},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.26126816868782043},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23863250017166138},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1739344298839569}],"mesh":[],"locations_count":8,"locations":[{"id":"doi:10.1038/s41467-024-49852-3","doi":"https://doi.org/10.1038/s41467-024-49852-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-49852-3","pdf_url":null,"source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"doi:10.1101/2023.08.28.555175","doi":"https://doi.org/10.1101/2023.08.28.555175","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.08.28.555175","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/08/29/2023.08.28.555175.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:11220080","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11220080","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:37693605","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37693605","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Preprint"},{"id":"pmid:38956413","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38956413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10491124","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10491124","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10491124/pdf/nihpp-2023.08.28.555175v1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-49852-3","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-024-49852-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:411877eea5cd4b39a0cc9ac097d58b2b","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/411877eea5cd4b39a0cc9ac097d58b2b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-024-49852-3","doi":"https://doi.org/10.1038/s41467-024-49852-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-024-49852-3","pdf_url":null,"source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2543901735","display_name":null,"funder_award_id":"1R16GM146703-01","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G4395214910","display_name":"The retinal clock modulates cell viability, retinal circuitry and locomotor activity rhythm","funder_award_id":"SC1GM135112","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4582713732","display_name":"Visualizing hierarchical processing of photic input to the circadian clock in vivo","funder_award_id":"R35GM136661","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4658142325","display_name":"Morehouse School of Medicine G12 Multidisciplinary Biomedical Research Center","funder_award_id":"G12RR003034","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G5341639710","display_name":"Melatonin Signaling in Photoreceptors","funder_award_id":"R21EY031821","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G6577187650","display_name":"Circadian regulation of RPE functions","funder_award_id":"R01EY026291","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G699655321","display_name":"Defining the role of sleep in resilience to social stress","funder_award_id":"SC1GM127260","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000867750","display_name":"Role of sex and protein degradation in the circadian clock","funder_award_id":"R35GM127044","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000883586","display_name":"Center for Translational Research in Health Disparities","funder_award_id":"U54MD007602","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"},{"id":"https://openalex.org/G9000893630","display_name":"Potential Role of Compass H3K4 Methyltransferase Complexes in Environmental Circadian-Alignment","funder_award_id":"R16GM146703","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337534","display_name":"National Institute on Minority Health and Health Disparities","ror":"https://ror.org/0493hgw16"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400260909.pdf","grobid_xml":"https://content.openalex.org/works/W4400260909.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W31275902","https://openalex.org/W108996981","https://openalex.org/W1259627718","https://openalex.org/W1761274245","https://openalex.org/W1970657971","https://openalex.org/W1971883897","https://openalex.org/W1979385177","https://openalex.org/W1984091490","https://openalex.org/W1989011389","https://openalex.org/W1989198547","https://openalex.org/W1991298209","https://openalex.org/W2000487298","https://openalex.org/W2009132775","https://openalex.org/W2011368229","https://openalex.org/W2012932442","https://openalex.org/W2024493318","https://openalex.org/W2027410128","https://openalex.org/W2033140176","https://openalex.org/W2036024950","https://openalex.org/W2036927231","https://openalex.org/W2044458189","https://openalex.org/W2051145352","https://openalex.org/W2053802535","https://openalex.org/W2056395995","https://openalex.org/W2078978479","https://openalex.org/W2091531174","https://openalex.org/W2092477191","https://openalex.org/W2101600063","https://openalex.org/W2107281049","https://openalex.org/W2111607030","https://openalex.org/W2115377255","https://openalex.org/W2126254382","https://openalex.org/W2133918896","https://openalex.org/W2135887929","https://openalex.org/W2140832481","https://openalex.org/W2140964378","https://openalex.org/W2152482858","https://openalex.org/W2154333461","https://openalex.org/W2156003764","https://openalex.org/W2164617868","https://openalex.org/W2345890567","https://openalex.org/W2436099095","https://openalex.org/W2523226413","https://openalex.org/W2556811098","https://openalex.org/W2567503091","https://openalex.org/W2743588819","https://openalex.org/W2752741846","https://openalex.org/W2777639606","https://openalex.org/W2786930746","https://openalex.org/W2788593837","https://openalex.org/W2795189268","https://openalex.org/W2801070441","https://openalex.org/W2903691731","https://openalex.org/W2928665623","https://openalex.org/W2950430276","https://openalex.org/W2991440671","https://openalex.org/W3006519311","https://openalex.org/W3043683397","https://openalex.org/W3081752501","https://openalex.org/W3107527779","https://openalex.org/W3117158612","https://openalex.org/W3139376559","https://openalex.org/W3165851349","https://openalex.org/W3178013431","https://openalex.org/W3199843879","https://openalex.org/W3216013705","https://openalex.org/W4280573294","https://openalex.org/W4291020590","https://openalex.org/W4294762760","https://openalex.org/W4297502053","https://openalex.org/W4376867268"],"related_works":["https://openalex.org/W4386243502","https://openalex.org/W1970657971","https://openalex.org/W2051145352","https://openalex.org/W7099857877","https://openalex.org/W2164498509","https://openalex.org/W2569303236","https://openalex.org/W7161734025","https://openalex.org/W2942603973","https://openalex.org/W2098132264","https://openalex.org/W7167335302"],"abstract_inverted_index":{"Circadian":[0],"gene":[1,48],"expression":[2],"is":[3,23,70,113],"fundamental":[4],"to":[5,74,88],"the":[6,11,71,85,98],"establishment":[7],"and":[8,16,32,41,54,59,81,106,122,130,133],"functions":[9],"of":[10,44,100,117,128,138],"circadian":[12,47,75,92,118,126],"clock,":[13],"a":[14,39],"cell-autonomous":[15],"evolutionary-conserved":[17],"timing":[18],"system.":[19],"Yet,":[20],"how":[21],"it":[22],"affected":[24],"by":[25],"environmental-circadian":[26],"disruption":[27],"(ECD)":[28],"such":[29],"as":[30],"shiftwork":[31],"jetlag":[33],"are":[34,84],"ill-defined.":[35],"Here,":[36],"we":[37],"provided":[38],"comprehensive":[40],"comparative":[42],"description":[43],"male":[45],"liver":[46],"expression,":[49],"encompassing":[50],"transcriptomes,":[51],"whole-cell":[52,89,104],"proteomes":[53],"nuclear":[55,91,108],"proteomes,":[56],"under":[57],"normal":[58],"after":[60,135],"ECD":[61,96],"conditions.":[62],"Under":[63],"both":[64],"conditions,":[65],"post-translation,":[66],"rather":[67],"than":[68],"transcription,":[69],"dominant":[72],"contributor":[73],"functional":[76],"outputs.":[77],"After":[78],"ECD,":[79],"post-transcriptional":[80],"post-translational":[82],"processes":[83],"major":[86],"contributors":[87],"or":[90],"proteome,":[93],"respectively.":[94],"Furthermore,":[95],"re-writes":[97],"rhythmicity":[99],"64%":[101],"transcriptome,":[102],"98%":[103],"proteome":[105],"95%":[107],"proteome.":[109],"The":[110],"re-writing,":[111],"which":[112],"associated":[114],"with":[115],"changes":[116],"regulatory":[119],"cis-elements,":[120],"RNA-processing":[121],"protein":[123],"localization,":[124],"diminishes":[125],"regulation":[127],"fat":[129],"carbohydrate":[131],"metabolism":[132],"persists":[134],"one":[136],"week":[137],"ECD-recovery.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2024-07-03T00:00:00"}
