{"id":"https://openalex.org/W4400106029","doi":"https://doi.org/10.3168/jds.2024-24762","title":"Metabolic clusters of early-lactating dairy cows based on blood \u03b2-hydroxybutyrate trajectories and predicted from milk compounds","display_name":"Metabolic clusters of early-lactating dairy cows based on blood \u03b2-hydroxybutyrate trajectories and predicted from milk compounds","publication_year":2024,"publication_date":"2024-06-28","ids":{"openalex":"https://openalex.org/W4400106029","doi":"https://doi.org/10.3168/jds.2024-24762","pmid":"https://pubmed.ncbi.nlm.nih.gov/38945267"},"language":"en","primary_location":{"id":"doi:10.3168/jds.2024-24762","doi":"https://doi.org/10.3168/jds.2024-24762","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2024-24762","pdf_url":null,"source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3168/jds.2024-24762","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045387482","display_name":"Muluken Mulat Girma","orcid":"https://orcid.org/0000-0003-4744-4357","observed_orcids":["https://orcid.org/0000-0003-4744-4357"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Muluken Girma","raw_affiliation_strings":["Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium. Electronic address: markosethio@yahoo.com","Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium. Electronic address: markosethio@yahoo.com","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027387266","display_name":"Stijn Heirbaut","orcid":"https://orcid.org/0000-0002-0432-2635","observed_orcids":["https://orcid.org/0000-0002-0432-2635"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"S. Heirbaut","raw_affiliation_strings":["Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium","Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":null,"display_name":"K. Hertogs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109617","display_name":"Inagro (Belgium)","ror":"https://ror.org/024wc1x05","country_code":"BE","type":"company","lineage":["https://openalex.org/I4210109617"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"K. Hertogs","raw_affiliation_strings":["Inagro, 8800 Rumbeke-Beitem, Belgium","Inagro, Ieperseweg 87, 8800 Rumbeke-Beitem, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inagro, 8800 Rumbeke-Beitem, Belgium","institution_ids":["https://openalex.org/I4210109617"]},{"raw_affiliation_string":"Inagro, Ieperseweg 87, 8800 Rumbeke-Beitem, Belgium","institution_ids":["https://openalex.org/I4210109617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062532592","display_name":"Xiaoping Jing","orcid":"https://orcid.org/0000-0003-1759-9366","observed_orcids":["https://orcid.org/0000-0003-1759-9366"]},"institutions":[{"id":"https://openalex.org/I4391768087","display_name":"State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems","ror":"https://ror.org/036xfaa94","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768087","https://openalex.org/I76214153"]},{"id":"https://openalex.org/I76214153","display_name":"Lanzhou University","ror":"https://ror.org/01mkqqe32","country_code":"CN","type":"education","lineage":["https://openalex.org/I76214153"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"X.P. Jing","raw_affiliation_strings":["State Key Laboratory of Grassland and Agro-Ecosystems, International Centre for Tibetan Plateau Ecosystem Management, School of Life Sciences, Lanzhou University, Lanzhou 730000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Grassland and Agro-Ecosystems, International Centre for Tibetan Plateau Ecosystem Management, School of Life Sciences, Lanzhou University, Lanzhou 730000, China","institution_ids":["https://openalex.org/I4391768087","https://openalex.org/I76214153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111241783","display_name":"Mengzhenyu Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"M.Q. Zhang","raw_affiliation_strings":["Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium","Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079720426","display_name":"P. Lutakome","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]},{"id":"https://openalex.org/I72227227","display_name":"Makerere University","ror":"https://ror.org/03dmz0111","country_code":"UG","type":"education","lineage":["https://openalex.org/I72227227"]}],"countries":["BE","UG"],"is_corresponding":false,"raw_author_name":"P. Lutakome","raw_affiliation_strings":["Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium; Department of Agricultural Production, College of Agricultural and Environmental Science, Makerere University, PO Box 7062, Kampala, Uganda","Department of Agricultureal Production, College of Agricultureal and Environmental Science, Makerere University, Kampala, Uganda","Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium; Department of Agricultural Production, College of Agricultural and Environmental Science, Makerere University, PO Box 7062, Kampala, Uganda","institution_ids":["https://openalex.org/I32597200","https://openalex.org/I72227227"]},{"raw_affiliation_string":"Department of Agricultureal Production, College of Agricultureal and Environmental Science, Makerere University, Kampala, Uganda","institution_ids":["https://openalex.org/I72227227"]},{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044731579","display_name":"Katleen Geerinckx","orcid":"https://orcid.org/0000-0002-9633-6670","observed_orcids":["https://orcid.org/0000-0002-9633-6670"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Geerinckx","raw_affiliation_strings":["Hooibeekhoeve, 2440 Geel, Belgium","Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hooibeekhoeve, 2440 Geel, Belgium","institution_ids":[]},{"raw_affiliation_string":"Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"S. Els","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Els","raw_affiliation_strings":["Hooibeekhoeve, 2440 Geel, Belgium","Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hooibeekhoeve, 2440 Geel, Belgium","institution_ids":[]},{"raw_affiliation_string":"Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038466387","display_name":"Ben Aernouts","orcid":"https://orcid.org/0000-0001-6266-3019","observed_orcids":["https://orcid.org/0000-0001-6266-3019"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Aernouts","raw_affiliation_strings":["Hooibeekhoeve, 2440 Geel, Belgium","Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hooibeekhoeve, 2440 Geel, Belgium","institution_ids":[]},{"raw_affiliation_string":"Hooibeekhoeve, Hooibeeksedijk 1, 2440 Geel, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037453409","display_name":"Leen Vandaele","orcid":"https://orcid.org/0000-0002-4563-6796","observed_orcids":["https://orcid.org/0000-0002-4563-6796"]},"institutions":[{"id":"https://openalex.org/I4210145253","display_name":"Instituut voor Landbouw en Visserijonderzoek","ror":"https://ror.org/05cjt1n05","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210145253"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"L. Vandaele","raw_affiliation_strings":["ILVO, 9090 Melle, Belgium","ILVO, Scheldeweg 68, 9090 Melle, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ILVO, 9090 Melle, Belgium","institution_ids":["https://openalex.org/I4210145253"]},{"raw_affiliation_string":"ILVO, Scheldeweg 68, 9090 Melle, Belgium","institution_ids":["https://openalex.org/I4210145253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054059771","display_name":"Veerle Fievez","orcid":"https://orcid.org/0000-0001-5042-6200","observed_orcids":["https://orcid.org/0000-0001-5042-6200"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"V. Fievez","raw_affiliation_strings":["Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium. Electronic address: veerle.fievez@ugent.be","Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, 9000 Ghent, Belgium. Electronic address: veerle.fievez@ugent.be","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Coupure Links 653, 9000, Gent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5045387482","https://openalex.org/A5054059771"],"corresponding_institution_ids":["https://openalex.org/I32597200"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":1.1397,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.7236814,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"107","issue":"11","first_page":"9719","last_page":"9734"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.9560999870300293,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10098","display_name":"Ruminant Nutrition and Digestive Physiology","score":0.021900000050663948,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-lactation","display_name":"early lactation","score":0.6520000100135803},{"id":"https://openalex.org/keywords/dairy-cows","display_name":"dairy cattle","score":0.6899999976158142},{"id":"https://openalex.org/keywords/blood-beta-hydroxybutyrate","display_name":"blood beta-hydroxybutyrate","score":0.8140000104904175},{"id":"https://openalex.org/keywords/metabolic-state","display_name":"metabolic status","score":0.5329999923706055},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.9490000009536743},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.9760000109672546},{"id":"https://openalex.org/keywords/milk-composition","display_name":"milk composition","score":0.796999990940094},{"id":"https://openalex.org/keywords/milk-fatty-acids","display_name":"milk fatty acids","score":0.8119999766349792},{"id":"https://openalex.org/keywords/milk-yield","display_name":"milk yield","score":0.7850000262260437},{"id":"https://openalex.org/keywords/dry-matter-intake","display_name":"dry matter intake","score":0.8820000290870667},{"id":"https://openalex.org/keywords/growth-mixture-modeling","display_name":"growth mixture modeling","score":0.7170000076293945},{"id":"https://openalex.org/keywords/holstein-cattle","display_name":"Holstein cows","score":0.7480000257492065},{"id":"https://openalex.org/keywords/inter-individual-variability","display_name":"interindividual variability","score":0.4909999966621399},{"id":"https://openalex.org/keywords/intra-individual-variability","display_name":"within-person variability","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C2779772378","wikidata":"https://www.wikidata.org/wiki/Q6953452","display_name":"NEFA","level":3,"score":0.7388932704925537},{"id":"https://openalex.org/C2776659692","wikidata":"https://www.wikidata.org/wiki/Q719426","display_name":"Lactation","level":3,"score":0.6194400191307068},{"id":"https://openalex.org/C2776977481","wikidata":"https://www.wikidata.org/wiki/Q2915","display_name":"Dairy cattle","level":2,"score":0.5408719778060913},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.53593510389328},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4908633828163147},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.4590207040309906},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3073671758174896},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.24353036284446716},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.11359885334968567},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005230","descriptor_name":"Fatty Acids, Nonesterified","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007774","descriptor_name":"Lactation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020155","descriptor_name":"3-Hydroxybutyric Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.3168/jds.2024-24762","doi":"https://doi.org/10.3168/jds.2024-24762","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2024-24762","pdf_url":null,"source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},{"id":"pmid:38945267","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38945267","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of dairy science","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:01JKWVHT6C0WX6HRGVG6GBDYXX","doi":null,"is_oa":true,"landing_page_url":"https://biblio.ugent.be/publication/01JKWVHT6C0WX6HRGVG6GBDYXX","pdf_url":"https://biblio.ugent.be/publication/01JKWVHT6C0WX6HRGVG6GBDYXX/file/01JKWVKJTXXC86E0YDPX68HDXH.pdf","source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1525-3198","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:20.500.12942/753495","doi":null,"is_oa":true,"landing_page_url":"https://lirias.kuleuven.be/handle/20.500.12942/753495","pdf_url":"https://lirias.kuleuven.be/retrieve/53f2ed14-e548-4e2b-840d-2d6f2abbbf6e","source":{"id":"https://openalex.org/S7407055369","display_name":"Lirias","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal Of Dairy Science, vol. 107 (11), (9719-9734)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3168/jds.2024-24762","doi":"https://doi.org/10.3168/jds.2024-24762","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2024-24762","pdf_url":null,"source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.8409000039100647,"id":"https://metadata.un.org/sdg/2"},{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4011635219","display_name":null,"funder_award_id":"2018/329","funder_id":"https://openalex.org/F4320337251","funder_display_name":"Instituut voor Landbouw-, Visserij- en Voedingsonderzoek, Vlaamse Overheid"},{"id":"https://openalex.org/G6684333953","display_name":null,"funder_award_id":"LA170830","funder_id":"https://openalex.org/F4320313460","funder_display_name":"Agentschap Innoveren en Ondernemen"}],"funders":[{"id":"https://openalex.org/F4320313460","display_name":"Agentschap Innoveren en Ondernemen","ror":"https://ror.org/032xdry56"},{"id":"https://openalex.org/F4320322603","display_name":"Universiteit Gent","ror":"https://ror.org/00cv9y106"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null},{"id":"https://openalex.org/F4320335227","display_name":"Bijzonder Onderzoeksfonds UGent","ror":"https://ror.org/00cv9y106"},{"id":"https://openalex.org/F4320337235","display_name":"Faculty of Veterinary Medicine, Kasetsart University","ror":null},{"id":"https://openalex.org/F4320337251","display_name":"Instituut voor Landbouw-, Visserij- en Voedingsonderzoek, Vlaamse Overheid","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4400106029.pdf","grobid_xml":"https://content.openalex.org/works/W4400106029.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W45547521","https://openalex.org/W83408023","https://openalex.org/W164651585","https://openalex.org/W626100886","https://openalex.org/W1480271113","https://openalex.org/W1774548452","https://openalex.org/W1817375627","https://openalex.org/W1971800738","https://openalex.org/W1972504489","https://openalex.org/W1983842902","https://openalex.org/W1986175730","https://openalex.org/W1986565721","https://openalex.org/W1989277554","https://openalex.org/W1993243925","https://openalex.org/W2003946092","https://openalex.org/W2013376826","https://openalex.org/W2018204863","https://openalex.org/W2018722560","https://openalex.org/W2038026694","https://openalex.org/W2043701337","https://openalex.org/W2055551138","https://openalex.org/W2057469323","https://openalex.org/W2060779558","https://openalex.org/W2074686769","https://openalex.org/W2088758496","https://openalex.org/W2102254164","https://openalex.org/W2104078534","https://openalex.org/W2114445980","https://openalex.org/W2115625532","https://openalex.org/W2117662946","https://openalex.org/W2121212588","https://openalex.org/W2121943809","https://openalex.org/W2155821018","https://openalex.org/W2157590687","https://openalex.org/W2159135906","https://openalex.org/W2159449865","https://openalex.org/W2165460886","https://openalex.org/W2168992001","https://openalex.org/W2188232396","https://openalex.org/W2204433279","https://openalex.org/W2473210296","https://openalex.org/W2477971128","https://openalex.org/W2770122864","https://openalex.org/W2916967667","https://openalex.org/W2996034883","https://openalex.org/W3003090043","https://openalex.org/W3005250480","https://openalex.org/W3094699016","https://openalex.org/W3110963935","https://openalex.org/W3157285591","https://openalex.org/W3164574598","https://openalex.org/W4308769522","https://openalex.org/W4376131254","https://openalex.org/W6624260203","https://openalex.org/W7033876411"],"related_works":["https://openalex.org/W4308769522","https://openalex.org/W7080236673","https://openalex.org/W2911886673","https://openalex.org/W6991085278","https://openalex.org/W2970380333","https://openalex.org/W7005423231","https://openalex.org/W4376131254","https://openalex.org/W2067726331","https://openalex.org/W2559833880","https://openalex.org/W3005152066"],"abstract_inverted_index":{"High-yielding":[0],"dairy":[1],"cows":[2,25,354,390,414,439,463,528],"encounter":[3],"metabolic":[4,22,68,89,173,187,214,234,335,370,525],"challenges":[5],"in":[6,32,43,65,145,172,344,388,451,472,498,502,539],"early":[7,33,540],"lactation.":[8,165,382,458,541],"Typically,":[9],"BHB,":[10,115],"measured":[11],"at":[12,126,292,299],"a":[13,28,93,100,202,244,277],"specific":[14],"time":[15,45],"point,":[16],"is":[17,36,508],"employed":[18,197],"to":[19,62,82,373],"diagnose":[20],"the":[21,50,53,63,78,161,176,183,198,212,223,236,268,288,300,303,307,315,329,333,365,378,424,454,461,478,485,490,496,503,506,511,515,534],"status":[23,69],"of":[24,52,80,102,114,137,164,178,185,225,259,302,381,430,444,457,460,492,510,514,527,536],"based":[26,189,532],"on":[27,190,253,533],"predetermined":[29],"threshold.":[30],"However,":[31],"lactation,":[34],"BHB":[35,81,180,227,239,247,258,271,279,290,298,309,318,321,385,426,538],"highly":[37],"dynamic,":[38],"with":[39,70,134,276,314,364,393,400,419],"high":[40],"interindividual":[41,168],"variability":[42],"its":[44],"profile.":[46],"This":[47,75],"could":[48,60,529],"limit":[49],"effectiveness":[51],"single":[54],"measurement":[55],"and":[56,59,72,86,120,130,140,154,169,181,222,262,286,306,324,347,352,358,375,396,402,422,447,467,495,517],"threshold-based":[57],"diagnosis":[58],"contribute":[61],"disparities":[64],"reports":[66],"linking":[67],"productive":[71],"reproductive":[73],"outcomes.":[74],"research":[76],"examines":[77],"trajectories":[79,177,535],"unveil":[83,208],"intercow":[84],"variations":[85,171],"identify":[87],"latent":[88,233],"groups.":[90],"We":[91,166],"compiled":[92],"dataset":[94,111],"from":[95,105,122],"2":[96],"observational":[97],"studies":[98],"involving":[99],"total":[101,448],"195":[103],"lactations":[104],"multiparous":[106],"Holstein":[107],"Friesian":[108],"cows.":[109,367,404,436],"The":[110,350,383,437],"encompasses":[112],"measurements":[113],"nonesterified":[116],"fatty":[117,141],"acids":[118,142],"(NEFA),":[119],"insulin":[121,348,360],"blood":[123,179,226,345,537],"samples":[124,501],"collected":[125],"3,":[127],"6,":[128],"9,":[129,285],"21":[131,294],"DIM,":[132],"along":[133,418],"weekly":[135],"determinations":[136],"milk":[138,146,151,452],"composition":[139],"(FA)":[143],"proportions":[144,443],"fat.":[147],"In":[148,522],"both":[149,219],"experiments,":[150],"yield":[152],"(MY)":[153],"feed":[155],"intake":[156],"were":[157,342,391,408],"recorded":[158],"daily":[159],"during":[160,377,453],"first":[162,379,455],"month":[163,380],"explored":[167],"intraindividual":[170],"responses":[174,215],"using":[175,464],"evaluated":[182],"presence":[184],"distinct":[186,524],"groups":[188,336,526],"such":[191],"variations.":[192],"For":[193],"this":[194],"purpose,":[195],"we":[196,230],"growth":[199],"mixture":[200],"model,":[201],"trajectory":[203,220],"clustering":[204],"technique.":[205],"Our":[206],"findings":[207],"novel":[209],"insights":[210],"into":[211],"diverse":[213],"among":[216,500],"cows,":[217],"encompassing":[218],"patterns":[221],"magnitude":[224],"concentrations.":[228,349],"Specifically,":[229],"identified":[231,531],"3":[232,334],"groups:":[235],"quickly":[237],"increasing":[238,270],"(QuiBHB)":[240],"cluster":[241,273,311],"(\u224810%)":[242],"exhibited":[243,337,355],"higher":[245,356,416,442],"initial":[246],"concentration":[248,291,319],"than":[249],"other":[250],"clusters,":[251],"peaked":[252],"d":[254,266,284,293],"9":[255],"(average":[256],"maximum":[257],"2.4":[260],"mM)":[261,323],"then":[263],"declined":[264],"by":[265],"21;":[267],"slowly":[269],"(SloBHB)":[272],"(\u224823%)":[274],"started":[275],"lower":[278,359,394],"concentration,":[280],"gradually":[281],"increased":[282,420],"until":[283],"reached":[287],"highest":[289],"(1.6":[295],"mM":[296],"serum":[297,317],"end":[301],"experimental":[304],"period);":[305],"low":[308],"(LoBHB)":[310],"(\u224867%)":[312],"began":[313],"lowest":[316],"(serum":[320],"<0.75":[322],"remained":[325],"relatively":[326],"stable":[327],"throughout":[328],"sampling":[330],"period.":[331],"Notably,":[332],"significant":[338],"physiological":[339],"disparities,":[340],"which":[341],"evident":[343],"NEFA":[346,357],"QuiBHB":[351,389,438,462],"SloBHB":[353,401,413],"concentrations":[361,386],"as":[362,398],"compared":[363,399],"LoBHB":[366,403],"Interestingly,":[368],"these":[369,406,435,465],"differences":[371],"extended":[372],"MY":[374,397,417],"DMI":[376,395],"elevated":[384,425],"observed":[387],"linked":[392],"Accordingly,":[405],"animals":[407],"considered":[409],"metabolically":[410],"impaired.":[411],"Conversely,":[412],"displayed":[415,441],"DMI,":[421],"thus":[423],"might":[427],"be":[428,530],"indicative":[429,509],"an":[431],"adaptive":[432],"response":[433],"for":[434,489,519],"also":[440],"UFA,":[445],"MUFA,":[446],"C18:1":[449],"FA":[450,466],"week":[456],"Prediction":[459],"test":[468],"day":[469],"variables":[470],"resulted":[471],"moderate":[473],"predictive":[474,512],"accuracy":[475],"(area":[476],"under":[477],"receiver":[479],"operating":[480],"characteristic":[481],"curve":[482],">0.7).":[483],"Given":[484],"limited":[486],"sample":[487],"size":[488],"development":[491],"prediction":[493],"models":[494],"variation":[497],"DIM":[499],"same":[504],"week,":[505],"result":[507],"potential":[513],"model":[516,520],"room":[518],"optimization.":[521],"summary,":[523]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2024-06-29T00:00:00"}
