{"id":"https://openalex.org/W4400105917","doi":"https://doi.org/10.1007/s42250-024-01021-1","title":"Cassia siamea Role in Diabetes Management: Insights from In vitro and In silico Investigations on \u03b1-Glucosidase and \u03b1-Amylase Inhibition","display_name":"Cassia siamea Role in Diabetes Management: Insights from In vitro and In silico Investigations on \u03b1-Glucosidase and \u03b1-Amylase Inhibition","publication_year":2024,"publication_date":"2024-06-28","ids":{"openalex":"https://openalex.org/W4400105917","doi":"https://doi.org/10.1007/s42250-024-01021-1"},"language":"en","primary_location":{"id":"doi:10.1007/s42250-024-01021-1","doi":"https://doi.org/10.1007/s42250-024-01021-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s42250-024-01021-1","pdf_url":null,"source":{"id":"https://openalex.org/S4210187402","display_name":"Chemistry Africa","issn_l":"2522-5758","issn":["2522-5758","2522-5766"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry Africa","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005125436","display_name":"Manish Ramchandani","orcid":"https://orcid.org/0000-0003-1738-8788","observed_orcids":["https://orcid.org/0000-0003-1738-8788"]},"institutions":[{"id":"https://openalex.org/I76777374","display_name":"Central University of Rajasthan","ror":"https://ror.org/056y7zx62","country_code":"IN","type":"education","lineage":["https://openalex.org/I76777374"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manish Ramchandani","raw_affiliation_strings":["Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India","institution_ids":["https://openalex.org/I76777374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058104020","display_name":"Rakesh Kumar Paul","orcid":"https://orcid.org/0000-0002-2269-3181","observed_orcids":["https://orcid.org/0000-0002-2269-3181"]},"institutions":[{"id":"https://openalex.org/I76777374","display_name":"Central University of Rajasthan","ror":"https://ror.org/056y7zx62","country_code":"IN","type":"education","lineage":["https://openalex.org/I76777374"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rakesh Kumar Paul","raw_affiliation_strings":["Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India","institution_ids":["https://openalex.org/I76777374"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Virendra Nath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76777374","display_name":"Central University of Rajasthan","ror":"https://ror.org/056y7zx62","country_code":"IN","type":"education","lineage":["https://openalex.org/I76777374"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Virendra Nath","raw_affiliation_strings":["Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India","institution_ids":["https://openalex.org/I76777374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070611428","display_name":"Vipin Kumar","orcid":"https://orcid.org/0000-0002-1484-0137","observed_orcids":["https://orcid.org/0000-0002-1484-0137","https://orcid.org/0009-0009-0274-1041"]},"institutions":[{"id":"https://openalex.org/I76777374","display_name":"Central University of Rajasthan","ror":"https://ror.org/056y7zx62","country_code":"IN","type":"education","lineage":["https://openalex.org/I76777374"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Vipin Kumar","raw_affiliation_strings":["Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India"],"raw_orcid":"https://orcid.org/0000-0002-1484-0137","affiliations":[{"raw_affiliation_string":"Department of Pharmacy, School of Chemical Sciences & Pharmacy, Central University of Rajasthan, Ajmer, 301817, India","institution_ids":["https://openalex.org/I76777374"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070611428"],"corresponding_institution_ids":["https://openalex.org/I76777374"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":null,"fwci":0.5237,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.6256982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"7","issue":"8","first_page":"4297","last_page":"4310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cassia-siamea","display_name":"Cassia siamea","score":1.0},{"id":"https://openalex.org/keywords/diabetes-management","display_name":"diabetes management","score":0.8980000019073486},{"id":"https://openalex.org/keywords/alpha-glucosidase-inhibition","display_name":"\u03b1-glucosidase inhibition","score":0.9559999704360962},{"id":"https://openalex.org/keywords/alpha-amylase-inhibition","display_name":"\u03b1-amylase inhibition","score":1.0},{"id":"https://openalex.org/keywords/antidiabetic-activity","display_name":"antidiabetic activity","score":0.7519999742507935},{"id":"https://openalex.org/keywords/leaf-extract","display_name":"leaf extract","score":0.7269999980926514},{"id":"https://openalex.org/keywords/percolation-extraction","display_name":"percolation extraction","score":0.8690000176429749},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.8679999709129333},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.9240000247955322}],"concepts":[{"id":"https://openalex.org/C2775939860","wikidata":"https://www.wikidata.org/wiki/Q162882","display_name":"Cassia","level":4,"score":0.9060503244400024},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.8903836011886597},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6545575261116028},{"id":"https://openalex.org/C170835558","wikidata":"https://www.wikidata.org/wiki/Q17153","display_name":"Amylase","level":3,"score":0.44193124771118164},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4042726755142212},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3521308898925781},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29756665229797363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23059287667274475},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21940401196479797},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19556212425231934},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.054778486490249634},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C188947578","wikidata":"https://www.wikidata.org/wiki/Q200253","display_name":"Traditional Chinese medicine","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s42250-024-01021-1","doi":"https://doi.org/10.1007/s42250-024-01021-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s42250-024-01021-1","pdf_url":null,"source":{"id":"https://openalex.org/S4210187402","display_name":"Chemistry Africa","issn_l":"2522-5758","issn":["2522-5758","2522-5766"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry Africa","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3403586909","display_name":null,"funder_award_id":"7(3) S&T/R&D/2016/2282","funder_id":"https://openalex.org/F4320326265","funder_display_name":"Department of Science and Technology, Government of Rajasthan"}],"funders":[{"id":"https://openalex.org/F4320326265","display_name":"Department of Science and Technology, Government of Rajasthan","ror":"https://ror.org/000830238"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W94930305","https://openalex.org/W1589514561","https://openalex.org/W1718201877","https://openalex.org/W1867945356","https://openalex.org/W1946502985","https://openalex.org/W1955434848","https://openalex.org/W2054931962","https://openalex.org/W2096965060","https://openalex.org/W2105289722","https://openalex.org/W2114657169","https://openalex.org/W2127670645","https://openalex.org/W2136505424","https://openalex.org/W2138432502","https://openalex.org/W2186161454","https://openalex.org/W2516886717","https://openalex.org/W2539864052","https://openalex.org/W2560449325","https://openalex.org/W2597582142","https://openalex.org/W2912616188","https://openalex.org/W2979250377","https://openalex.org/W2995371808"],"related_works":["https://openalex.org/W7217623173","https://openalex.org/W3032524704","https://openalex.org/W4387018314","https://openalex.org/W7136143256","https://openalex.org/W2791618004","https://openalex.org/W2149635161","https://openalex.org/W4320927208","https://openalex.org/W4367846456","https://openalex.org/W2750319727","https://openalex.org/W4205203844"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2024-06-29T00:00:00"}