{"id":"https://openalex.org/W4400102083","doi":"https://doi.org/10.1016/j.cjac.2024.100414","title":"Radiosensitizer-based injectable hydrogel for enhanced radio-chemotherapy of TNBC","display_name":"Radiosensitizer-based injectable hydrogel for enhanced radio-chemotherapy of TNBC","publication_year":2024,"publication_date":"2024-06-27","ids":{"openalex":"https://openalex.org/W4400102083","doi":"https://doi.org/10.1016/j.cjac.2024.100414"},"language":"en","primary_location":{"id":"doi:10.1016/j.cjac.2024.100414","doi":"https://doi.org/10.1016/j.cjac.2024.100414","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cjac.2024.100414","pdf_url":null,"source":{"id":"https://openalex.org/S4394735505","display_name":"Chinese Journal of Analytical Chemistry","issn_l":"1872-2040","issn":["1872-2040"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Journal of Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.cjac.2024.100414","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018852939","display_name":"Jie An","orcid":"https://orcid.org/0000-0001-9260-9697","observed_orcids":["https://orcid.org/0000-0001-9260-9697","https://orcid.org/0009-0003-1790-4102"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie AN","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111241581","display_name":"Kaile CHU","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaile CHU","raw_affiliation_strings":["Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China","Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046393441","display_name":"Qin C Zhou","orcid":"https://orcid.org/0000-0003-1225-2902","observed_orcids":["https://orcid.org/0000-0003-1225-2902"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin ZHOU","raw_affiliation_strings":["Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China","Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy of Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Huizhu MA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huizhu MA","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063320976","display_name":"Qianwen He","orcid":"https://orcid.org/0009-0003-4779-0492","observed_orcids":["https://orcid.org/0009-0003-4779-0492"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianwen HE","raw_affiliation_strings":["Department of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Basic Medical Sciences, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101464007","display_name":"Yaqiong Zhang","orcid":"https://orcid.org/0000-0002-7673-4591","observed_orcids":["https://orcid.org/0000-0002-7673-4591"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"YaQiong ZHANG","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Junping LV","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junping LV","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015099801","display_name":"Hua Wei","orcid":"https://orcid.org/0000-0003-4341-8290","observed_orcids":["https://orcid.org/0000-0003-4341-8290","https://orcid.org/0000-0003-0023-2605","https://orcid.org/0009-0005-6345-7985"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua WEI","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100719013","display_name":"Min Li","orcid":"https://orcid.org/0000-0002-0188-1394","observed_orcids":["https://orcid.org/0000-0002-0188-1394"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min LI","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100667022","display_name":"Zhifang Wu","orcid":"https://orcid.org/0000-0001-9027-7051","observed_orcids":["https://orcid.org/0000-0001-9027-7051"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhifang WU","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100708326","display_name":"Sijin Li","orcid":"https://orcid.org/0000-0002-5867-8362","observed_orcids":["https://orcid.org/0000-0002-5867-8362"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I4210125748","display_name":"First Hospital of Shanxi Medical University","ror":"https://ror.org/02vzqaq35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125748"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Sijin LI","raw_affiliation_strings":["Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center for Molecular Imaging of Precision Medicine Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]},{"raw_affiliation_string":"Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Molecular Imaging, Shanxi Medical University, Taiyuan 030001, PR China","institution_ids":["https://openalex.org/I17721919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100667022","https://openalex.org/A5100708326","https://openalex.org/A5100719013"],"corresponding_institution_ids":["https://openalex.org/I17721919","https://openalex.org/I4210125748"],"apc_list":null,"apc_paid":null,"fwci":1.8671,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.84584358,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"52","issue":"7","first_page":"100414","last_page":"100414"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.8457000255584717,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.1128000020980835,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.029100000858306885,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radionuclide-therapy","display_name":"radionuclide therapy","score":0.8550000190734863},{"id":"https://openalex.org/keywords/radiosensitizers","display_name":"radiosensitizers","score":0.7689999938011169},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.8930000066757202},{"id":"https://openalex.org/keywords/injectable-hydrogel","display_name":"injectable hydrogel","score":0.8709999918937683},{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.7820000052452087},{"id":"https://openalex.org/keywords/polydopamine","display_name":"polydopamine","score":0.7990000247955322},{"id":"https://openalex.org/keywords/gemcitabine","display_name":"gemcitabine","score":0.9800000190734863},{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"chemoradiotherapy","score":0.7590000033378601},{"id":"https://openalex.org/keywords/chitosan","display_name":"chitosan","score":0.8489999771118164},{"id":"https://openalex.org/keywords/spect-imaging","display_name":"SPECT imaging","score":0.8399999737739563},{"id":"https://openalex.org/keywords/tumor-radioresistance","display_name":"tumor radioresistance","score":0.5979999899864197},{"id":"https://openalex.org/keywords/dna-repair-inhibition","display_name":"DNA repair inhibition","score":0.5799999833106995},{"id":"https://openalex.org/keywords/cell-cycle-redistribution","display_name":"cell cycle redistribution","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C2776428644","wikidata":"https://www.wikidata.org/wiki/Q2126468","display_name":"Radiosensitizer","level":3,"score":0.7013006806373596},{"id":"https://openalex.org/C2780258809","wikidata":"https://www.wikidata.org/wiki/Q414143","display_name":"Gemcitabine","level":3,"score":0.6341838836669922},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5846049189567566},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5285483598709106},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5071637630462646},{"id":"https://openalex.org/C58962609","wikidata":"https://www.wikidata.org/wiki/Q2353022","display_name":"Radioresistance","level":3,"score":0.47499457001686096},{"id":"https://openalex.org/C2993559085","wikidata":"https://www.wikidata.org/wiki/Q2126444","display_name":"Radionuclide therapy","level":2,"score":0.4725486934185028},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4005934000015259},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39159953594207764},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.373447060585022},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35287028551101685},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.31887900829315186},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11487624049186707},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0932685136795044},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.cjac.2024.100414","doi":"https://doi.org/10.1016/j.cjac.2024.100414","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cjac.2024.100414","pdf_url":null,"source":{"id":"https://openalex.org/S4394735505","display_name":"Chinese Journal of Analytical Chemistry","issn_l":"1872-2040","issn":["1872-2040"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Journal of Analytical Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.cjac.2024.100414","doi":"https://doi.org/10.1016/j.cjac.2024.100414","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cjac.2024.100414","pdf_url":null,"source":{"id":"https://openalex.org/S4394735505","display_name":"Chinese Journal of Analytical Chemistry","issn_l":"1872-2040","issn":["1872-2040"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chinese Journal of Analytical Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1043112586","display_name":null,"funder_award_id":"62005150","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G211115865","display_name":null,"funder_award_id":"81971655","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2263521804","display_name":null,"funder_award_id":"82027804","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G236055488","display_name":null,"funder_award_id":"(U22A6008)","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4045165141","display_name":null,"funder_award_id":"82203221","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7570020326","display_name":null,"funder_award_id":"20210302124175","funder_id":"https://openalex.org/F4320331088","funder_display_name":"Natural Science Foundation for Young Scientists of Shanxi Province"},{"id":"https://openalex.org/G980879365","display_name":null,"funder_award_id":"82102103","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320331088","display_name":"Natural Science Foundation for Young Scientists of Shanxi Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W2019378544","https://openalex.org/W2132124638","https://openalex.org/W2136162480","https://openalex.org/W2169365607","https://openalex.org/W2530072344","https://openalex.org/W2618955899","https://openalex.org/W2799978121","https://openalex.org/W2969065707","https://openalex.org/W2994826525","https://openalex.org/W3002941444","https://openalex.org/W3029701621","https://openalex.org/W3034049106","https://openalex.org/W3117191995","https://openalex.org/W3127698042","https://openalex.org/W3128646645","https://openalex.org/W3141589386","https://openalex.org/W3148713131","https://openalex.org/W3160921080","https://openalex.org/W3195414690","https://openalex.org/W4200503278","https://openalex.org/W4206243938","https://openalex.org/W4213360309","https://openalex.org/W4221067648","https://openalex.org/W4226156828","https://openalex.org/W4285241947","https://openalex.org/W4312195030","https://openalex.org/W4361276116","https://openalex.org/W4366772427","https://openalex.org/W4367833948","https://openalex.org/W4381033545","https://openalex.org/W4384522453","https://openalex.org/W4386865659","https://openalex.org/W4388802369","https://openalex.org/W4389322863","https://openalex.org/W6773113605","https://openalex.org/W6778584285","https://openalex.org/W6794214421"],"related_works":["https://openalex.org/W2118940674","https://openalex.org/W2913827242","https://openalex.org/W2766459017","https://openalex.org/W2398587680","https://openalex.org/W4388737332","https://openalex.org/W3081723185","https://openalex.org/W94590171","https://openalex.org/W2411480694","https://openalex.org/W2051227018","https://openalex.org/W2148311954"],"abstract_inverted_index":{"Radionuclide":[0],"therapy":[1,185,211],"(RNT)":[2],"stands":[3],"out":[4],"as":[5,84],"a":[6,48,67,85,148],"highly":[7],"effective":[8],"method":[9],"for":[10,80,170,208],"treating":[11],"solid":[12],"tumors.":[13],"However,":[14],"its":[15],"therapeutic":[16,196],"efficiency":[17],"faces":[18],"challenges":[19],"due":[20],"to":[21,91,96,117,143],"the":[22,26,61,107,127,132,138,158,188,213],"radioresistance":[23],"of":[24,33,41,131,140,190,216],"tumors,":[25],"limited":[27],"penetration":[28],"depth":[29],"and":[30,73,99,134,155,168],"intracellular":[31],"deposition":[32],"rays":[34],"in":[35,104,110,123,126,153,165,212],"tumor":[36,111,201],"tissue,":[37],"which":[38,103,146],"causes":[39],"residue":[40],"living":[42],"cancer":[43,81],"cells.":[44,112],"Herein,":[45],"we":[46],"report":[47],"novel":[49],"approach":[50],"by":[51],"utilizing":[52],"radionuclide":[53,166,210],"131I-labelled":[54],"polydopamine":[55],"encapsulated":[56],"gold":[57],"nanoparticle":[58],"co-loaded":[59],"with":[60,78,93,179],"classical":[62],"anticancer":[63],"drug":[64],"gemcitabine":[65,114,135],"within":[66],"hydrogel":[68,160],"formed":[69],"from":[70],"oxidized":[71],"glucan":[72],"chitosan":[74],"hydrochloride,":[75],"combining":[76],"RNT":[77,181],"chemotherapy":[79],"treatment.":[82],"Au,":[83],"high":[86],"Z":[87],"element,":[88],"is":[89,115],"able":[90,116],"interact":[92],"short-range":[94],"\u03b2-rays":[95],"emit":[97],"bremsstrahlung":[98],"secondary":[100],"charged":[101],"particles":[102],"turn":[105],"increase":[106,125],"dose":[108],"deposited":[109],"Simultaneously,":[113],"affect":[118],"cell":[119],"cycle":[120],"redistribution,":[121],"resulting":[122],"an":[124,199],"radiosensitive":[128],"cellular":[129,144],"component":[130],"cycle,":[133],"also":[136],"inhibits":[137,187],"repair":[139],"radioactive":[141],"damage":[142],"DNA,":[145],"has":[147],"radiosensitizing":[149],"effect.":[150],"In":[151],"both":[152],"vivo":[154],"vitro":[156],"experiments,":[157],"injectable":[159],"demonstrates":[161],"excellent":[162],"biosecurity,":[163],"stability":[164],"labeling,":[167],"capabilities":[169],"single-photon":[171],"emission":[172],"computed":[173],"tomography":[174],"(SPECT)":[175],"imaging.":[176],"Compared":[177],"analysis":[178],"single":[180],"revealed":[182],"that":[183],"combination":[184],"markedly":[186],"growth":[189],"triple-negative":[191],"breast":[192],"cancer.":[193,217],"This":[194],"integrated":[195],"strategy":[197],"establishes":[198],"efficient":[200],"synergistic":[202],"treatment":[203,215],"platform,":[204],"offering":[205],"new":[206],"avenues":[207],"advancing":[209],"clinical":[214]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2025-10-10T00:00:00"}