{"id":"https://openalex.org/W4399802407","doi":"https://doi.org/10.7554/elife.91398.4","title":"Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology","display_name":"Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology","publication_year":2024,"publication_date":"2024-06-19","ids":{"openalex":"https://openalex.org/W4399802407","doi":"https://doi.org/10.7554/elife.91398.4"},"language":"en","primary_location":{"id":"doi:10.7554/elife.91398.4","doi":"https://doi.org/10.7554/elife.91398.4","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.91398.4","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.91398.4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073527268","display_name":"Harshvardhan Gazula","orcid":"https://orcid.org/0000-0001-9318-8871","observed_orcids":["https://orcid.org/0000-0001-9318-8871"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harshvardhan Gazula","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015372912","display_name":"Henry F. J. Tregidgo","orcid":"https://orcid.org/0000-0002-3509-8154","observed_orcids":["https://orcid.org/0000-0002-3509-8154"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Henry FJ Tregidgo","raw_affiliation_strings":["Centre for Medical Image Computing, University College London"],"raw_orcid":"https://orcid.org/0000-0002-3509-8154","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036774610","display_name":"Benjamin Billot","orcid":"https://orcid.org/0000-0002-3018-1282","observed_orcids":["https://orcid.org/0000-0002-3018-1282"]},"institutions":[{"id":"https://openalex.org/I4405258931","display_name":"MIT Computer Science and Artificial Intelligence Laboratory","ror":"https://ror.org/01e85r662","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Billot","raw_affiliation_strings":["Computer Science and Artificial Intelligence Laboratory, MIT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science and Artificial Intelligence Laboratory, MIT","institution_ids":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089640308","display_name":"Ya\u00ebl Balbastre","orcid":"https://orcid.org/0000-0001-8758-9978","observed_orcids":["https://orcid.org/0000-0001-8758-9978"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yael Balbastre","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099244506","display_name":"Jonathan Williams-Ramirez","orcid":"https://orcid.org/0009-0008-8645-5773","observed_orcids":["https://orcid.org/0009-0008-8645-5773"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Williams-Ramirez","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092130313","display_name":"Rogeny Herisse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rogeny Herisse","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093474611","display_name":"Lucas J Deden-Binder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucas J Deden-Binder","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063668258","display_name":"Adri\u00e0 Casamitjana","orcid":"https://orcid.org/0000-0002-0539-3638","observed_orcids":["https://orcid.org/0000-0002-0539-3638"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES","GB"],"is_corresponding":false,"raw_author_name":"Adria Casamitjana","raw_affiliation_strings":["Biomedical Imaging Group, Universitat Polit\u00e8cnica de Catalunya","Centre for Medical Image Computing, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Imaging Group, Universitat Polit\u00e8cnica de Catalunya","institution_ids":["https://openalex.org/I9617848"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025936663","display_name":"Erica J. Melief","orcid":"https://orcid.org/0000-0002-3570-3289","observed_orcids":["https://orcid.org/0000-0002-3570-3289"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erica J Melief","raw_affiliation_strings":["BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035909512","display_name":"Caitlin S. Latimer","orcid":"https://orcid.org/0000-0003-3727-4278","observed_orcids":["https://orcid.org/0000-0003-3727-4278"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caitlin S Latimer","raw_affiliation_strings":["BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072713575","display_name":"Mitchell D. Kilgore","orcid":"https://orcid.org/0000-0003-1101-6924","observed_orcids":["https://orcid.org/0000-0003-1101-6924"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell D Kilgore","raw_affiliation_strings":["BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine"],"raw_orcid":"https://orcid.org/0000-0003-1101-6924","affiliations":[{"raw_affiliation_string":"BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092130310","display_name":"Mark Montine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Montine","raw_affiliation_strings":["BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016778344","display_name":"Eleanor Robinson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Eleanor Robinson","raw_affiliation_strings":["Centre for Medical Image Computing, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015567903","display_name":"Emily Blackburn","orcid":"https://orcid.org/0000-0003-4009-2715","observed_orcids":["https://orcid.org/0000-0003-4009-2715"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emily Blackburn","raw_affiliation_strings":["Centre for Medical Image Computing, University College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael S Marshall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S Marshall","raw_affiliation_strings":["Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042568470","display_name":"Theresa R. Connors","orcid":"https://orcid.org/0000-0002-9706-8217","observed_orcids":["https://orcid.org/0000-0002-9706-8217"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa R Connors","raw_affiliation_strings":["Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074495346","display_name":"Derek H. Oakley","orcid":"https://orcid.org/0000-0002-6998-9510","observed_orcids":["https://orcid.org/0000-0002-6998-9510"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Derek H Oakley","raw_affiliation_strings":["Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005004760","display_name":"Matthew P. Frosch","orcid":"https://orcid.org/0000-0002-3940-9861","observed_orcids":["https://orcid.org/0000-0002-3940-9861"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew P Frosch","raw_affiliation_strings":["Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102909580","display_name":"Sean I. Young","orcid":"https://orcid.org/0000-0002-4304-1959","observed_orcids":["https://orcid.org/0000-0002-4304-1959"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sean I Young","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047520245","display_name":"Koen Van Leemput","orcid":"https://orcid.org/0000-0001-6466-5309","observed_orcids":["https://orcid.org/0000-0001-6466-5309"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI","US"],"is_corresponding":false,"raw_author_name":"Koen Van Leemput","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","Neuroscience and Biomedical Engineering, Aalto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Neuroscience and Biomedical Engineering, Aalto University","institution_ids":["https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091409910","display_name":"Adrian Vasile Dalca","orcid":"https://orcid.org/0000-0002-8422-0136","observed_orcids":["https://orcid.org/0000-0002-8422-0136"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4405258931","display_name":"MIT Computer Science and Artificial Intelligence Laboratory","ror":"https://ror.org/01e85r662","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adrian V Dalca","raw_affiliation_strings":["Computer Science and Artificial Intelligence Laboratory, MIT","Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science and Artificial Intelligence Laboratory, MIT","institution_ids":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022799533","display_name":"Bruce R. Fischl","orcid":"https://orcid.org/0000-0002-2413-1115","observed_orcids":["https://orcid.org/0000-0002-2413-1115"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce Fischl","raw_affiliation_strings":["Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108694759","display_name":"Christine MacDonald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine L MacDonald","raw_affiliation_strings":["Department of Neurological Surgery, UW School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031692016","display_name":"Christopher Dirk Keene","orcid":"https://orcid.org/0000-0002-5291-1469","observed_orcids":["https://orcid.org/0000-0002-5291-1469"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Dirk Keene","raw_affiliation_strings":["BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine"],"raw_orcid":"https://orcid.org/0000-0002-5291-1469","affiliations":[{"raw_affiliation_string":"BioRepository and Integrated Neuropathology (BRaIN) Laboratory and Precision Neuropathology Core, UW School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068688487","display_name":"Bradley T. Hyman","orcid":"https://orcid.org/0000-0002-7959-9401","observed_orcids":["https://orcid.org/0000-0002-7959-9401"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradley T Hyman","raw_affiliation_strings":["Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School"],"raw_orcid":"https://orcid.org/0000-0002-7959-9401","affiliations":[{"raw_affiliation_string":"Massachusetts Alzheimer Disease Research Center, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054888342","display_name":"Juan Eugenio Iglesias","orcid":"https://orcid.org/0000-0001-7569-173X","observed_orcids":["https://orcid.org/0000-0001-7569-173X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I4405258931","display_name":"MIT Computer Science and Artificial Intelligence Laboratory","ror":"https://ror.org/01e85r662","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Juan E Iglesias","raw_affiliation_strings":["Centre for Medical Image Computing, University College London","Computer Science and Artificial Intelligence Laboratory, MIT","Martinos Center for Biomedical Imaging, MGH and Harvard Medical School"],"raw_orcid":"https://orcid.org/0000-0001-7569-173X","affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Computer Science and Artificial Intelligence Laboratory, MIT","institution_ids":["https://openalex.org/I4405258931","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Martinos Center for Biomedical Imaging, MGH and Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":0.1393,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.38503023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"12","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11984","display_name":"Anatomy and Medical Technology","score":0.02239999920129776,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surface-scanning","display_name":"surface scanning","score":0.7440000176429749},{"id":"https://openalex.org/keywords/3d-reconstruction","display_name":"3D reconstruction","score":0.8600000143051147},{"id":"https://openalex.org/keywords/brain-structure-segmentation","display_name":"brain structure segmentation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/volume-measurement","display_name":"volume measurement","score":0.7929999828338623},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8389999866485596},{"id":"https://openalex.org/keywords/brain-banks","display_name":"brain banks","score":0.7110000252723694},{"id":"https://openalex.org/keywords/freesurfer","display_name":"FreeSurfer","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6272397041320801},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.6191814541816711},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6117972135543823},{"id":"https://openalex.org/C2780130745","wikidata":"https://www.wikidata.org/wiki/Q1650750","display_name":"Neuropathology","level":3,"score":0.6107453107833862},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.568108856678009},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5659266710281372},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5399290323257446},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.46191051602363586},{"id":"https://openalex.org/C2779751349","wikidata":"https://www.wikidata.org/wiki/Q1474480","display_name":"Scanner","level":2,"score":0.41436833143234253},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3711695671081543},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3643202781677246},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.35309505462646484},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30046266317367554},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.26080602407455444},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23481935262680054},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.19900396466255188},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1660841703414917},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.15244555473327637},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08836627006530762},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.7554/elife.91398.4","doi":"https://doi.org/10.7554/elife.91398.4","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.91398.4","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},{"id":"pmh:oai:upcommons.upc.edu:2117/464899","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2117/464899","pdf_url":null,"source":{"id":"https://openalex.org/S4377196262","display_name":"UPCommons institutional repository (Universitat Polit\u00e8cnica de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I9617848","host_organization_name":"Universitat Polit\u00e8cnica de Catalunya","host_organization_lineage":["https://openalex.org/I9617848"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.7554/elife.91398.4","doi":"https://doi.org/10.7554/elife.91398.4","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.91398.4","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7246000170707703,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2326022803","display_name":"Molecular Mechanisms of Synergistic TDP-43 and Tau Proteotoxicity in Alzheimer's Disease","funder_award_id":"K08AG065426","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2923474247","display_name":"Computational Imaging Biomarkers of Multiple Sclerosis","funder_award_id":"R01NS112161","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3417970972","display_name":"Segmenting Brain Structures for Neurological Disorders","funder_award_id":"R01NS105820","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4062758774","display_name":"Inferring in Vivo Cytoarchitectural Borders in the Medial Temporal Lobe","funder_award_id":"R01EB006758","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G4216980111","display_name":"Algorithms for MR and OCT-based Architectonic and Laminar Segmentation","funder_award_id":"R01EB019956","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G4259104258","display_name":"The Human Connectome Project (HCP)","funder_award_id":"U01MH093765","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G461408552","display_name":"OCTology: histology using optical coherence tomography","funder_award_id":"R21EB018907","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G4688137892","display_name":"Deep Learning Algorithms for FreeSurfer","funder_award_id":"R56AG064027","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G5769766104","display_name":"Accelerated Software Tools for Neuroimaging Analysis","funder_award_id":"R21NS072652","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5870051173","display_name":"Nobrainer: A robust and validated neural network tool suite for imagers","funder_award_id":"RF1MH121885","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6073090889","display_name":null,"funder_award_id":"ARUK-IRG2019A-003","funder_id":"https://openalex.org/F4320321081","funder_display_name":"Alzheimer\u2019s Research UK"},{"id":"https://openalex.org/G6097830111","display_name":"Computeserver Structural &Functional Image Analysis","funder_award_id":"1s10rr019307-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6296793415","display_name":null,"funder_award_id":"R01NS0525851","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6382590792","display_name":"MRI, Genetics & Cognitive Precursors of AD and Dementia","funder_award_id":"R01AG016495","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6657296360","display_name":"Open-source software for multi-scale mapping of the human brain","funder_award_id":"1rf1mh123195-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7621422906","display_name":"Software Tools for Automated Modeling of White Matter Fascicles from Diffusion MR","funder_award_id":"R01NS070963","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8779974883","display_name":"Epidemiology of Dementia in the Framingham Study","funder_award_id":"R01AG008122","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G8801679355","display_name":"A Storage Area Network for Structural and Functional Image Analysis","funder_award_id":"S10RR023401","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G8953057465","display_name":"Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain","funder_award_id":"U01MH117023","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000163195","display_name":null,"funder_award_id":"5U01NS086625","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000287168","display_name":null,"funder_award_id":"P30AG066509 (UW ADRC)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000300321","display_name":null,"funder_award_id":"1R01AG064027","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000859074","display_name":"A Longitudinal Analysis Stream for FreeSurfer","funder_award_id":"R01NS083534","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000870417","display_name":"Functionally guided adult whole brain cell atlas in human and NHP","funder_award_id":"UM1MH130981","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000872788","display_name":"Adult Changes in Thought (ACT) Research Program","funder_award_id":"U19AG066567","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000877543","display_name":"VCID Biomarkers Coordinating Center","funder_award_id":"U24NS100591","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000881276","display_name":"FreeSurfer Development, Maintenance, and Hardening","funder_award_id":"R01EB023281","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G9000881766","display_name":"Center for Mesoscale Mapping","funder_award_id":"P41EB030006","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G9000888481","display_name":"Portable, Low Field Brain Magnetic Resonance Imaging (MRI) for Acute Stroke","funder_award_id":"R01EB031114","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G9000903406","display_name":"Diagnosing the undiagnosable: studies of Alzheimer disease mimics and confounders via \"neuropathometry\" of dissection photos with 3D scanning","funder_award_id":"R01AG070988","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000916845","display_name":"Massachusetts Alzheimer's Disease Research Center (MADRC)","funder_award_id":"P30AG062421","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000921292","display_name":"A multimodal brain cell atlas and community resource of Alzheimer's disease and comorbid dementias.","funder_award_id":"U19AG060909","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G95811799","display_name":"Silicon Graphics Prism Extreme 128P/1TB","funder_award_id":"1s10rr023043-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321081","display_name":"Alzheimer\u2019s Research UK","ror":"https://ror.org/02ymzm013"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1522301498","https://openalex.org/W1529992670","https://openalex.org/W1587800983","https://openalex.org/W1836465849","https://openalex.org/W1972978214","https://openalex.org/W1987869189","https://openalex.org/W2004293194","https://openalex.org/W2020519533","https://openalex.org/W2028158228","https://openalex.org/W2035079822","https://openalex.org/W2035464869","https://openalex.org/W2071076969","https://openalex.org/W2077658674","https://openalex.org/W2083099567","https://openalex.org/W2096931656","https://openalex.org/W2101135654","https://openalex.org/W2101487986","https://openalex.org/W2115167851","https://openalex.org/W2118386984","https://openalex.org/W2124386111","https://openalex.org/W2133584444","https://openalex.org/W2143017382","https://openalex.org/W2147555557","https://openalex.org/W2156875677","https://openalex.org/W2176412452","https://openalex.org/W2432481613","https://openalex.org/W2514101822","https://openalex.org/W2559207392","https://openalex.org/W2605102758","https://openalex.org/W2606708158","https://openalex.org/W2621028221","https://openalex.org/W2737094118","https://openalex.org/W2741171560","https://openalex.org/W2793622148","https://openalex.org/W2956916445","https://openalex.org/W2982697854","https://openalex.org/W3048650577","https://openalex.org/W3086534490","https://openalex.org/W3195593055","https://openalex.org/W4241074797","https://openalex.org/W4296580612","https://openalex.org/W4309583361","https://openalex.org/W4318767763","https://openalex.org/W4321440702","https://openalex.org/W4321760728","https://openalex.org/W6783726833"],"related_works":["https://openalex.org/W3086534490","https://openalex.org/W7144035361","https://openalex.org/W4416038046","https://openalex.org/W7098835132","https://openalex.org/W7203628080","https://openalex.org/W4390196290","https://openalex.org/W7116855383","https://openalex.org/W7126735666","https://openalex.org/W2132457274","https://openalex.org/W1989432482"],"abstract_inverted_index":{"We":[0,96],"present":[1],"open-source":[2],"tools":[3,30,67,99,150],"for":[4,26,74],"three-dimensional":[5],"(3D)":[6],"analysis":[7],"of":[8,10,13,62],"photographs":[9,39],"dissected":[11],"slices":[12],"human":[14],"brains,":[15],"which":[16,81],"are":[17,127,151],"routinely":[18],"acquired":[19],"in":[20,59,153],"brain":[21,54],"banks":[22],"but":[23],"seldom":[24],"used":[25,70],"quantitative":[27],"analysis.":[28],"Our":[29,66,134],"can:":[31],"(1)":[32],"3D":[33,50,120],"reconstruct":[34],"a":[35,42,48,72],"volume":[36],"from":[37,105,132],"the":[38,63],"and,":[40],"optionally,":[41],"surface":[43],"scan;":[44],"and":[45,92,102,123,147],"(2)":[46],"produce":[47],"high-resolution":[49],"segmentation":[51],"into":[52],"11":[53],"regions":[55],"per":[56],"hemisphere":[57],"(22":[58],"total),":[60],"independently":[61],"slice":[64],"thickness.":[65],"can":[68],"be":[69],"as":[71],"substitute":[73],"ex":[75,88],"vivo":[76,89],"magnetic":[77],"resonance":[78],"imaging":[79],"(MRI),":[80],"requires":[82],"access":[83],"to":[84,130],"an":[85],"MRI":[86],"scanner,":[87],"scanning":[90],"expertise,":[91],"considerable":[93],"\ufb01nancial":[94],"resources.":[95],"tested":[97],"our":[98,116,154],"on":[100],"synthetic":[101],"real":[103],"data":[104],"two":[106],"NIH":[107],"Alzheimer\u2019s":[108,144],"Disease":[109],"Research":[110],"Centers.":[111],"The":[112,149],"results":[113],"show":[114],"that":[115,126],"methodology":[117],"yields":[118],"accurate":[119],"reconstructions,":[121],"segmentations,":[122],"volumetric":[124],"measurements":[125],"highly":[128],"correlated":[129],"those":[131],"MRI.":[133],"method":[135],"also":[136],"detects":[137],"expected":[138],"di\ufb00erences":[139],"between":[140],"post":[141],"mortem":[142],"con\ufb01rmed":[143],"disease":[145],"cases":[146],"controls.":[148],"available":[152],"widespread":[155],"neuroimaging":[156],"suite":[157],"\u2018FreeSurfer\u2019":[158],"(":[159],"https://surfer.nmr.mgh.harvard.edu/fswiki/PhotoTools":[160],").":[161]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-06-20T00:00:00"}