{"id":"https://openalex.org/W4399736378","doi":"https://doi.org/10.1158/2767-9764.26049370","title":"FIGURE 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation","display_name":"FIGURE 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation","publication_year":2024,"publication_date":"2024-06-17","ids":{"openalex":"https://openalex.org/W4399736378","doi":"https://doi.org/10.1158/2767-9764.26049370"},"language":"en","primary_location":{"id":"doi:10.1158/2767-9764.26049370","doi":"https://doi.org/10.1158/2767-9764.26049370","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.26049370","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2767-9764.26049370","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008460713","display_name":"Laura Bukavina","orcid":"https://orcid.org/0000-0001-7129-6230","observed_orcids":["https://orcid.org/0000-0001-7129-6230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura Bukavina","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7129-6230","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018610795","display_name":"Rashida Ginwala","orcid":"https://orcid.org/0009-0009-1283-3433","observed_orcids":["https://orcid.org/0009-0009-1283-3433"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rashida Ginwala","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-1283-3433","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093536840","display_name":"Mohamed Eltoukhi","orcid":"https://orcid.org/0009-0002-1578-0890","observed_orcids":["https://orcid.org/0009-0002-1578-0890"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohamed Eltoukhi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-1578-0890","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071084557","display_name":"Mohit Sindhani","orcid":"https://orcid.org/0009-0007-5950-2784","observed_orcids":["https://orcid.org/0009-0007-5950-2784"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohit Sindhani","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-5950-2784","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015886470","display_name":"Megan C. Prunty","orcid":"https://orcid.org/0000-0002-9150-6706","observed_orcids":["https://orcid.org/0000-0002-9150-6706"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Megan Prunty","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9150-6706","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033372450","display_name":"Daniel M. Geynisman","orcid":"https://orcid.org/0000-0002-1423-5295","observed_orcids":["https://orcid.org/0000-0002-1423-5295"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel M. Geynisman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1423-5295","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079166812","display_name":"Pooja Ghatalia","orcid":"https://orcid.org/0000-0001-6229-7581","observed_orcids":["https://orcid.org/0000-0001-6229-7581"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pooja Ghatalia","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6229-7581","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026525677","display_name":"Henkel Valentine","orcid":"https://orcid.org/0000-0001-6869-3497","observed_orcids":["https://orcid.org/0000-0001-6869-3497"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henkel Valentine","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6869-3497","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041167898","display_name":"Adam Christopher Calaway","orcid":"https://orcid.org/0000-0001-6716-3806","observed_orcids":["https://orcid.org/0000-0001-6716-3806"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adam Calaway","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6716-3806","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040964782","display_name":"Andres F. Correa","orcid":"https://orcid.org/0000-0001-8506-7324","observed_orcids":["https://orcid.org/0000-0001-8506-7324"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andres F. Correa","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8506-7324","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057674148","display_name":"Jason Robert Brown","orcid":"https://orcid.org/0000-0001-6225-7555","observed_orcids":["https://orcid.org/0000-0001-6225-7555"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jason R. Brown","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6225-7555","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033872684","display_name":"Kirtishri Mishra","orcid":"https://orcid.org/0000-0001-6468-7858","observed_orcids":["https://orcid.org/0000-0001-6468-7858"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kirtishri Mishra","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6468-7858","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032422193","display_name":"Elizabeth R. Plimack","orcid":"https://orcid.org/0000-0002-7618-0744","observed_orcids":["https://orcid.org/0000-0002-7618-0744"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elizabeth R. Plimack","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7618-0744","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091629756","display_name":"Alexander Kutikov","orcid":"https://orcid.org/0000-0003-1525-6247","observed_orcids":["https://orcid.org/0000-0003-1525-6247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Kutikov","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1525-6247","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089635085","display_name":"Mahmoud Afif Ghannoum","orcid":"https://orcid.org/0000-0002-8833-7323","observed_orcids":["https://orcid.org/0000-0002-8833-7323"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud Ghannoum","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8833-7323","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027731913","display_name":"Mohammed Youssef Saad Elshaer","orcid":"https://orcid.org/0000-0002-0179-2869","observed_orcids":["https://orcid.org/0000-0002-0179-2869"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammed Elshaer","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0179-2869","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019459050","display_name":"Mauricio Retuerto","orcid":"https://orcid.org/0009-0004-0612-6402","observed_orcids":["https://orcid.org/0009-0004-0612-6402"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mauricio Retuerto","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0004-0612-6402","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018694224","display_name":"Lee Evan Ponsky","orcid":"https://orcid.org/0000-0002-1252-3285","observed_orcids":["https://orcid.org/0000-0002-1252-3285"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lee Ponsky","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1252-3285","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043554307","display_name":"Robert G. Uzzo","orcid":"https://orcid.org/0000-0003-2398-6530","observed_orcids":["https://orcid.org/0000-0003-2398-6530"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert G. Uzzo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2398-6530","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5011122559","display_name":"Philip H. Abbosh","orcid":"https://orcid.org/0000-0003-3611-9532","observed_orcids":["https://orcid.org/0000-0003-3611-9532"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Philip H. Abbosh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3611-9532","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.48019999265670776,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.48019999265670776,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.4772999882698059,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neoadjuvant-chemotherapy","display_name":"neoadjuvant chemotherapy","score":0.9160000085830688},{"id":"https://openalex.org/keywords/urothelial-carcinoma","display_name":"urothelial carcinoma","score":0.9670000076293945},{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"bladder cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/complete-response","display_name":"complete response","score":0.7789999842643738},{"id":"https://openalex.org/keywords/microbial-taxa","display_name":"microbial taxa","score":0.45500001311302185},{"id":"https://openalex.org/keywords/alpha-diversity","display_name":"alpha diversity","score":0.7829999923706055},{"id":"https://openalex.org/keywords/unifrac","display_name":"UniFrac","score":0.6629999876022339},{"id":"https://openalex.org/keywords/lefse","display_name":"LEfSe","score":0.7749999761581421},{"id":"https://openalex.org/keywords/differentially-abundant-taxa","display_name":"differentially abundant taxa","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5897805094718933},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5585544109344482},{"id":"https://openalex.org/C3019882237","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Urothelial carcinoma","level":4,"score":0.553203821182251},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5512939691543579},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5481635928153992},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5422296524047852},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.5179837942123413},{"id":"https://openalex.org/C3019978661","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut microbiome","level":3,"score":0.4813597798347473},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4668102264404297},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15220028162002563},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.14305412769317627},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.14025285840034485},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.06247451901435852}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/2767-9764.26049370","doi":"https://doi.org/10.1158/2767-9764.26049370","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.26049370","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/2767-9764.26049370","doi":"https://doi.org/10.1158/2767-9764.26049370","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.26049370","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4396924601","https://openalex.org/W4399736445","https://openalex.org/W4399736153","https://openalex.org/W4399736376","https://openalex.org/W4399736426","https://openalex.org/W4394800999","https://openalex.org/W2338471384","https://openalex.org/W3170594206","https://openalex.org/W4399736374","https://openalex.org/W6927563914"],"abstract_inverted_index":{"Microbial":[0],"composition":[1,20],"variance":[2],"in":[3,8,21,31,77],"relation":[4],"to":[5,27],"chemotherapy":[6],"response":[7,39,57],"patients":[9,22],"with":[10,73,84],"bladder":[11],"cancer.":[12],"A,":[13],"Proportional":[14],"representation":[15],"of":[16,52],"the":[17,50],"GM's":[18],"phylogenetic":[19],"showing":[23],"CR":[24,79],"versus":[25],"NR":[26,81],"NAC":[28,74],"(Also":[29],"depicted":[30],"C).":[32],"B,":[33],"Alpha":[34],"diversity":[35],"metrics":[36],"compared":[37],"across":[38],"groups,":[40,82],"highlighting":[41],"minimal":[42],"statistical":[43],"disparities.":[44],"D,":[45],"Weighted":[46],"UniFrac":[47],"PCoA":[48],"depicting":[49],"lack":[51],"distinct":[53],"microbial":[54,70],"clustering":[55],"by":[56],"category.":[58],"E\u2013G,":[59],"Venn":[60],"diagram":[61],"and":[62,67],"LEfSe":[63],"analysis":[64],"illustrating":[65],"unique":[66],"differentially":[68],"abundant":[69],"taxa":[71],"associated":[72],"responses,":[75],"enriched":[76],"either":[78],"or":[80],"along":[83],"a":[85],"taxonomic":[86],"cladogram":[87],"delineating":[88],"these":[89],"associations.":[90]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2024-06-18T00:00:00"}