{"id":"https://openalex.org/W4399725933","doi":"https://doi.org/10.4049/jimmunol.2400243","title":"NKT Cells and Other Innate T Cells: The Immune Cells That Do Not Follow the Rules","display_name":"NKT Cells and Other Innate T Cells: The Immune Cells That Do Not Follow the Rules","publication_year":2024,"publication_date":"2024-06-17","ids":{"openalex":"https://openalex.org/W4399725933","doi":"https://doi.org/10.4049/jimmunol.2400243","pmid":"https://pubmed.ncbi.nlm.nih.gov/38885470","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12305014"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.2400243","doi":"https://doi.org/10.4049/jimmunol.2400243","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.2400243","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12305014/pdf/nihms-2096979.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033614715","display_name":"Kalyani Pyaram","orcid":"https://orcid.org/0000-0003-2744-7470","observed_orcids":["https://orcid.org/0000-0003-2744-7470"]},"institutions":[{"id":"https://openalex.org/I4210128618","display_name":"University of Kansas Medical Center","ror":"https://ror.org/036c9yv20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210128618"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kalyani Pyaram","raw_affiliation_strings":["*Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS"],"raw_orcid":"https://orcid.org/0000-0003-2744-7470","affiliations":[{"raw_affiliation_string":"*Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS","institution_ids":["https://openalex.org/I4210128618"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051704016","display_name":"Cheong\u2010Hee Chang","orcid":"https://orcid.org/0000-0001-8725-852X","observed_orcids":["https://orcid.org/0000-0001-8725-852X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Cheong-Hee Chang","raw_affiliation_strings":["Department of Microbiology and Immunology"],"raw_orcid":"https://orcid.org/0000-0001-8725-852X","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5033614715","https://openalex.org/A5051704016"],"corresponding_institution_ids":["https://openalex.org/I4210128618"],"apc_list":{"value":3710,"currency":"USD","value_usd":3710},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08200507,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"213","issue":"1","first_page":"3","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nkt-cells","display_name":"NKT cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/innate-t-cells","display_name":"innate T cells","score":0.984000027179718},{"id":"https://openalex.org/keywords/cd4-thymocytes","display_name":"CD4+ thymocytes","score":0.9769999980926514},{"id":"https://openalex.org/keywords/thymocyte-selection","display_name":"thymic selection","score":0.7749999761581421},{"id":"https://openalex.org/keywords/t-cell-development","display_name":"T cell development","score":0.6759999990463257},{"id":"https://openalex.org/keywords/history-of-immunology","display_name":"history of immunology","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7195780277252197},{"id":"https://openalex.org/C139563560","wikidata":"https://www.wikidata.org/wiki/Q224930","display_name":"Natural killer T cell","level":4,"score":0.6329748034477234},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5560076236724854},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.49081405997276306},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.45792824029922485},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4316239655017853},{"id":"https://openalex.org/C37386791","wikidata":"https://www.wikidata.org/wiki/Q2248081","display_name":"CD1","level":5,"score":0.42995357513427734},{"id":"https://openalex.org/C47742525","wikidata":"https://www.wikidata.org/wiki/Q13418826","display_name":"Innate lymphoid cell","level":4,"score":0.4225192964076996},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.41062402725219727},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40641671419143677},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.3904629051685333},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.368174284696579},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.28384363651275635},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.24545997381210327},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.06966695189476013},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D055611","descriptor_name":"Natural Killer T-Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.4049/jimmunol.2400243","doi":"https://doi.org/10.4049/jimmunol.2400243","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.2400243","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:38885470","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38885470","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunology (Baltimore, Md. : 1950)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12305014","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12305014","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12305014/pdf/nihms-2096979.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Immunol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12305014","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12305014","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12305014/pdf/nihms-2096979.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Immunol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6067378579","display_name":"Regulation of metabolic pathways in NKT cells","funder_award_id":"R01AI148289","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4399725933.pdf","grobid_xml":"https://content.openalex.org/works/W4399725933.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1510858436","https://openalex.org/W1571056008","https://openalex.org/W1601061296","https://openalex.org/W1975137285","https://openalex.org/W1978757502","https://openalex.org/W1981751053","https://openalex.org/W2001958607","https://openalex.org/W2010366356","https://openalex.org/W2013255473","https://openalex.org/W2014805484","https://openalex.org/W2025795383","https://openalex.org/W2030817385","https://openalex.org/W2038057643","https://openalex.org/W2046746241","https://openalex.org/W2057812734","https://openalex.org/W2072581592","https://openalex.org/W2081913102","https://openalex.org/W2093497258","https://openalex.org/W2121477549","https://openalex.org/W2155255799","https://openalex.org/W2158117877","https://openalex.org/W2159130192","https://openalex.org/W2160069839","https://openalex.org/W2161307276","https://openalex.org/W2164259326","https://openalex.org/W2165246784","https://openalex.org/W2461304145","https://openalex.org/W2618404796","https://openalex.org/W2755270150","https://openalex.org/W2923756133","https://openalex.org/W2936344227","https://openalex.org/W2952411693","https://openalex.org/W4307584298","https://openalex.org/W4311707779","https://openalex.org/W4375955899","https://openalex.org/W4387670823"],"related_works":["https://openalex.org/W2066595032","https://openalex.org/W2946697493","https://openalex.org/W2401475969","https://openalex.org/W2085387086","https://openalex.org/W2779425331","https://openalex.org/W2148058784","https://openalex.org/W3007036799","https://openalex.org/W33924759","https://openalex.org/W4254570174","https://openalex.org/W2244314875"],"abstract_inverted_index":{"Abstract":[0],"This":[1],"Pillars":[2],"of":[3,12,42,54],"Immunology":[4],"article":[5,23],"is":[6],"a":[7,21],"commentary":[8],"on":[9],"\u201cA":[10],"subset":[11],"CD4+":[13],"thymocytes":[14],"selected":[15],"by":[16,24],"MHC":[17],"class":[18],"I":[19],"molecules,\u201d":[20],"pivotal":[22],"A.":[25],"Bendelac,":[26],"N.":[27],"Killeen,":[28],"D.R.":[29],"Littman,":[30],"and":[31,45,52],"R.H.":[32],"Schwartz":[33],"published":[34],"in":[35,37],"Science":[36],"1994,":[38],"marking":[39],"the":[40,47,50],"discovery":[41],"NKT":[43],"cells":[44],"paving":[46],"way":[48],"for":[49],"identification":[51],"characterization":[53],"other":[55],"innate":[56],"T":[57],"cells.":[58],"https://doi.org/10.1126/science.7907820.":[59]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-06-18T00:00:00"}