{"id":"https://openalex.org/W4399472187","doi":"https://doi.org/10.1002/hon.3282","title":"Clonal dynamics of Richter transformation in chronic lymphocytic leukemia","display_name":"Clonal dynamics of Richter transformation in chronic lymphocytic leukemia","publication_year":2024,"publication_date":"2024-06-09","ids":{"openalex":"https://openalex.org/W4399472187","doi":"https://doi.org/10.1002/hon.3282","pmid":"https://pubmed.ncbi.nlm.nih.gov/38852069"},"language":"en","primary_location":{"id":"doi:10.1002/hon.3282","doi":"https://doi.org/10.1002/hon.3282","is_oa":false,"landing_page_url":"https://doi.org/10.1002/hon.3282","pdf_url":null,"source":{"id":"https://openalex.org/S23714410","display_name":"Hematological Oncology","issn_l":"0278-0232","issn":["0278-0232","1099-1069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematological Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101491465","display_name":"Hanyin Wang","orcid":"https://orcid.org/0000-0001-7649-0892","observed_orcids":["https://orcid.org/0000-0001-7649-0892"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4210123409","display_name":"Mayo Clinic Health System","ror":"https://ror.org/02zzw8g45","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210123409"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hanyin Wang","raw_affiliation_strings":["Division of Hospital Internal Medicine, Mayo Clinic Health System, Mankato, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0001-7649-0892","affiliations":[{"raw_affiliation_string":"Division of Hospital Internal Medicine, Mayo Clinic Health System, Mankato, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210123409"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112893135","display_name":"Shulan Tian","orcid":"https://orcid.org/0000-0002-3348-7439","observed_orcids":["https://orcid.org/0000-0002-3348-7439"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shulan Tian","raw_affiliation_strings":["Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041539604","display_name":"Charla R. Secreto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charla R. Secreto","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088390990","display_name":"Sutapa Sinha","orcid":"https://orcid.org/0000-0002-7274-9622","observed_orcids":["https://orcid.org/0000-0002-7274-9622"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sutapa Sinha","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029811322","display_name":"Min Shi","orcid":"https://orcid.org/0000-0002-5741-4293","observed_orcids":["https://orcid.org/0000-0002-5741-4293"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Min Shi","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0002-5741-4293","affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051752737","display_name":"Timothy G. Call","orcid":"https://orcid.org/0000-0002-8465-9587","observed_orcids":["https://orcid.org/0000-0002-8465-9587"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Call","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102945222","display_name":"Yucai Wang","orcid":"https://orcid.org/0000-0002-1576-8341","observed_orcids":["https://orcid.org/0000-0002-1576-8341"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yucai Wang","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0002-1576-8341","affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009747339","display_name":"Sameer Ashok Parikh","orcid":"https://orcid.org/0000-0002-3221-7314","observed_orcids":["https://orcid.org/0000-0002-3221-7314"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sameer A. Parikh","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0002-3221-7314","affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054196868","display_name":"Saad S. Kenderian","orcid":"https://orcid.org/0000-0003-2767-3830","observed_orcids":["https://orcid.org/0000-0003-2767-3830"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saad S. Kenderian","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0003-2767-3830","affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079731167","display_name":"Rong Lucy He","orcid":"https://orcid.org/0000-0001-6116-8163","observed_orcids":["https://orcid.org/0000-0001-6116-8163","https://orcid.org/0000-0002-6011-5964"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rong He","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0001-6116-8163","affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112062579","display_name":"Jose Francisco Leis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4210127938","display_name":"Mayo Clinic Hospital","ror":"https://ror.org/03660jn93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4210127938"]},{"id":"https://openalex.org/I4390039332","display_name":"Mayo Clinic Comprehensive Cancer Center (Arizona)","ror":"https://ror.org/003xpy695","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4390039332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose F. Leis","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210127938","https://openalex.org/I4390039332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111985257","display_name":"Daniel L. VanDyke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel L. VanDyke","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044058635","display_name":"Eric W. Klee","orcid":"https://orcid.org/0000-0003-2946-5795","observed_orcids":["https://orcid.org/0000-0003-2946-5795"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric W. Klee","raw_affiliation_strings":["Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067100969","display_name":"Susan L. Slager","orcid":"https://orcid.org/0000-0002-5173-4712","observed_orcids":["https://orcid.org/0000-0002-5173-4712"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan L. Slager","raw_affiliation_strings":["Division of Computational Biology, Mayo Clinic, Rochester, Minnesota, USA","Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Computational Biology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082845313","display_name":"Esteban Braggio","orcid":"https://orcid.org/0000-0003-3860-4830","observed_orcids":["https://orcid.org/0000-0003-3860-4830"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4210127938","display_name":"Mayo Clinic Hospital","ror":"https://ror.org/03660jn93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4210127938"]},{"id":"https://openalex.org/I4390039332","display_name":"Mayo Clinic Comprehensive Cancer Center (Arizona)","ror":"https://ror.org/003xpy695","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4390039332"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esteban Braggio","raw_affiliation_strings":["Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210127938","https://openalex.org/I4390039332"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085730035","display_name":"Huihuang Yan","orcid":"https://orcid.org/0000-0003-0756-2922","observed_orcids":["https://orcid.org/0000-0003-0756-2922"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huihuang Yan","raw_affiliation_strings":["Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075005037","display_name":"Wei Ding","orcid":"https://orcid.org/0000-0001-9811-4601","observed_orcids":["https://orcid.org/0000-0001-9811-4601"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Ding","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":"https://orcid.org/0000-0001-9811-4601","affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101491465"],"corresponding_institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210123409"],"apc_list":{"value":4430,"currency":"USD","value_usd":4430},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10050586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"4","first_page":"e3282","last_page":"e3282"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/richter-transformation","display_name":"Richter transformation","score":0.9710000157356262},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.9950000047683716},{"id":"https://openalex.org/keywords/clonal-dynamics","display_name":"clonal dynamics","score":0.9269999861717224},{"id":"https://openalex.org/keywords/b-cell-lymphoma","display_name":"B-cell lymphoma","score":0.5619999766349792},{"id":"https://openalex.org/keywords/clonal-evolution","display_name":"clonal evolution","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C2777938653","wikidata":"https://www.wikidata.org/wiki/Q1088156","display_name":"Chronic lymphocytic leukemia","level":3,"score":0.7774335145950317},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.5588419437408447},{"id":"https://openalex.org/C113968399","wikidata":"https://www.wikidata.org/wiki/Q7559241","display_name":"Somatic evolution in cancer","level":3,"score":0.5434281229972839},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4233381152153015},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.4113304615020752},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4041270911693573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.315669447183609},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2645217776298523},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.262426495552063},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21147772669792175},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.15119710564613342},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.08874443173408508},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015451","descriptor_name":"Leukemia, Lymphocytic, Chronic, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D060965","descriptor_name":"Clonal Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/hon.3282","doi":"https://doi.org/10.1002/hon.3282","is_oa":false,"landing_page_url":"https://doi.org/10.1002/hon.3282","pdf_url":null,"source":{"id":"https://openalex.org/S23714410","display_name":"Hematological Oncology","issn_l":"0278-0232","issn":["0278-0232","1099-1069"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematological Oncology","raw_type":"journal-article"},{"id":"pmid:38852069","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38852069","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematological oncology","raw_type":"Letter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7160429521","display_name":"Targeting Akt Activation in CLL","funder_award_id":"K23CA160345","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8549715945","display_name":"Lymphoma Specialized Program of Research Excellence (SPORE) in Human Cancer","funder_award_id":"P50CA097274","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000128122","display_name":null,"funder_award_id":"CA97274","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000868933","display_name":"Mayo Clinic Center for Clinical and Translational Science (CCaTS)","funder_award_id":"UL1TR002377","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000881388","display_name":"Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic","funder_award_id":"K12CA090628","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320307776","display_name":"Merck","ror":"https://ror.org/02891sr49"},{"id":"https://openalex.org/F4320309501","display_name":"Richard M. Schulze Family Foundation","ror":"https://ror.org/01jm2xz84"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1982158899","https://openalex.org/W2066764749","https://openalex.org/W2088580309","https://openalex.org/W2129650489","https://openalex.org/W2136272158","https://openalex.org/W2561792671","https://openalex.org/W2610704467","https://openalex.org/W2654931540","https://openalex.org/W2773946416","https://openalex.org/W2899369036","https://openalex.org/W2909227549","https://openalex.org/W3041932899","https://openalex.org/W3106137033","https://openalex.org/W3210809682","https://openalex.org/W4225091971","https://openalex.org/W4313830893"],"related_works":["https://openalex.org/W4292363624","https://openalex.org/W2981138891","https://openalex.org/W4292243363","https://openalex.org/W3206701489","https://openalex.org/W6982382750","https://openalex.org/W2253032999","https://openalex.org/W3202971565","https://openalex.org/W7128810270","https://openalex.org/W1999470438","https://openalex.org/W2001025559"],"abstract_inverted_index":{"The":[0,23],"peer":[1],"review":[2],"history":[3],"for":[4,28,54],"this":[5],"article":[6],"is":[7,13,25],"available":[8,14],"at":[9],"https://www.webofscience.com/api/gateway/wos/peer-review/10.1002/hon.3282.":[10],"All":[11],"data":[12],"on":[15],"request":[16],"from":[17],"the":[18,29,39,51,55],"corresponding":[19,52],"author.":[20],"Please":[21],"note:":[22],"publisher":[24],"not":[26],"responsible":[27],"content":[30],"or":[31],"functionality":[32],"of":[33],"any":[34],"supporting":[35],"information":[36],"supplied":[37],"by":[38],"authors.":[40],"Any":[41],"queries":[42],"(other":[43],"than":[44],"missing":[45],"content)":[46],"should":[47],"be":[48],"directed":[49],"to":[50],"author":[53],"article.":[56]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-06-10T00:00:00"}