{"id":"https://openalex.org/W4399293403","doi":"https://doi.org/10.56042/ijeb.v62i06.3788","title":"Inhibitory effect of thymoquinone and capsaicin on Blastocystis grown in vitro","display_name":"Inhibitory effect of thymoquinone and capsaicin on Blastocystis grown in vitro","publication_year":2024,"publication_date":"2024-06-03","ids":{"openalex":"https://openalex.org/W4399293403","doi":"https://doi.org/10.56042/ijeb.v62i06.3788"},"language":"en","primary_location":{"id":"doi:10.56042/ijeb.v62i06.3788","doi":"https://doi.org/10.56042/ijeb.v62i06.3788","is_oa":true,"landing_page_url":"https://doi.org/10.56042/ijeb.v62i06.3788","pdf_url":null,"source":{"id":"https://openalex.org/S188457412","display_name":"Indian Journal of Experimental Biology","issn_l":"0019-5189","issn":["0019-5189","0975-1009"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-70"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Experimental Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.56042/ijeb.v62i06.3788","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092555535","display_name":"SAADET YILDIZ","orcid":"https://orcid.org/0000-0003-1566-2931","observed_orcids":["https://orcid.org/0000-0003-1566-2931"]},"institutions":[{"id":"https://openalex.org/I118567650","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l \u00dcniversitesi","ror":"https://ror.org/041jyzp61","country_code":"TR","type":"education","lineage":["https://openalex.org/I118567650"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Saadet Y\u0131ld\u0131z","raw_affiliation_strings":["Department of Parasitology, Medical Faculty, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l UniversityVan, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Medical Faculty, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l UniversityVan, T\u00fcrkiye","institution_ids":["https://openalex.org/I118567650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033716071","display_name":"Selahattin Aydemir","orcid":"https://orcid.org/0000-0002-0941-2779","observed_orcids":["https://orcid.org/0000-0002-0941-2779"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Selahattin Aydemir","raw_affiliation_strings":["YES"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"YES","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079960177","display_name":"Abdurrahman Ekici","orcid":"https://orcid.org/0000-0001-6034-513X","observed_orcids":["https://orcid.org/0000-0001-6034-513X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abdurrahman Ekici","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076245663","display_name":"Naziye Y\u0131ld\u0131z Deniz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Naziye Y\u0131ld\u0131z Deniz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100637687","display_name":"Hasan Y\u0131lmaz","orcid":"https://orcid.org/0000-0001-6947-4499","observed_orcids":["https://orcid.org/0000-0001-6947-4499","https://orcid.org/0000-0002-3640-2621"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hasan Y\u0131lmaz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7495,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62832041,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"62","issue":"06","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.9160000085830688,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12750","display_name":"Nigella sativa pharmacological applications","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blastocystis","display_name":"Blastocystis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thymoquinone","display_name":"thymoquinone","score":1.0},{"id":"https://openalex.org/keywords/capsaicin","display_name":"capsaicin","score":1.0},{"id":"https://openalex.org/keywords/metronidazole","display_name":"metronidazole","score":0.7919999957084656},{"id":"https://openalex.org/keywords/antiparasitic-activity","display_name":"antiparasitic activity","score":0.8389999866485596}],"concepts":[{"id":"https://openalex.org/C2779034068","wikidata":"https://www.wikidata.org/wiki/Q7799650","display_name":"Thymoquinone","level":3,"score":0.985197126865387},{"id":"https://openalex.org/C2780051329","wikidata":"https://www.wikidata.org/wiki/Q273169","display_name":"Capsaicin","level":3,"score":0.7661992311477661},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.7483718395233154},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6206763982772827},{"id":"https://openalex.org/C2778092740","wikidata":"https://www.wikidata.org/wiki/Q1756496","display_name":"Blastocystis","level":3,"score":0.6080141663551331},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.46252119541168213},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.4499557316303253},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4443422555923462},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3267609179019928},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.317844033241272},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3137966990470886},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14786744117736816},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12025216221809387},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.06858444213867188},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.56042/ijeb.v62i06.3788","doi":"https://doi.org/10.56042/ijeb.v62i06.3788","is_oa":true,"landing_page_url":"https://doi.org/10.56042/ijeb.v62i06.3788","pdf_url":null,"source":{"id":"https://openalex.org/S188457412","display_name":"Indian Journal of Experimental Biology","issn_l":"0019-5189","issn":["0019-5189","0975-1009"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-70"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Experimental Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.56042/ijeb.v62i06.3788","doi":"https://doi.org/10.56042/ijeb.v62i06.3788","is_oa":true,"landing_page_url":"https://doi.org/10.56042/ijeb.v62i06.3788","pdf_url":null,"source":{"id":"https://openalex.org/S188457412","display_name":"Indian Journal of Experimental Biology","issn_l":"0019-5189","issn":["0019-5189","0975-1009"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-70"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Experimental Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W29759587","https://openalex.org/W75247640","https://openalex.org/W1974768397","https://openalex.org/W2015553609","https://openalex.org/W2052203472","https://openalex.org/W2056653443","https://openalex.org/W2091141094","https://openalex.org/W2156215259","https://openalex.org/W2334616152","https://openalex.org/W2346704000","https://openalex.org/W2584364866","https://openalex.org/W2600764640","https://openalex.org/W2796131579","https://openalex.org/W2797129711","https://openalex.org/W2909577203","https://openalex.org/W2943620586","https://openalex.org/W2944755431","https://openalex.org/W2997548566","https://openalex.org/W3011566388","https://openalex.org/W3018041402","https://openalex.org/W3109941432","https://openalex.org/W3126927562","https://openalex.org/W3136240553","https://openalex.org/W3152447897","https://openalex.org/W4310046295","https://openalex.org/W4318323729","https://openalex.org/W4362513778","https://openalex.org/W4366826131","https://openalex.org/W4387613860"],"related_works":["https://openalex.org/W4402669308","https://openalex.org/W4390846190","https://openalex.org/W4310046295","https://openalex.org/W3111602974","https://openalex.org/W4413949142","https://openalex.org/W4405672500","https://openalex.org/W4380864173","https://openalex.org/W2742257981","https://openalex.org/W2124206943","https://openalex.org/W2115096492"],"abstract_inverted_index":{"Blastocystis":[0,22,78,124,142,154],"is":[1,15],"enteric":[2],"parasites":[3],"that":[4,129,153,179],"live":[5],"in":[6,18,57,76,82,85,159],"both":[7],"humans":[8],"and":[9,32,71,96,105,113,120,134,147,161,191],"animals":[10],"gastrointestinal":[11],"tracts.":[12],"Metronidazole":[13],"(MTZ)":[14],"generally":[16],"preferred":[17],"the":[19,58,65,145,167,173],"treatment":[20,59],"of":[21,60,68,103,132,137,141],"infection.":[23],"However,":[24],"it":[25,150],"has":[26],"been":[27],"shown":[28],"to":[29,47,172,189],"have":[30,43],"teratogenic":[31],"carcinogenic":[33],"potential,":[34],"causing":[35],"various":[36],"side":[37,55],"effects.":[38,125],"In":[39,144],"this":[40,63],"study,":[41],"we":[42],"made":[44],"an":[45,49,164],"attempt":[46],"find":[48],"alternative":[50],"drug":[51,187],"with":[52,91,156],"less":[53],"toxic":[54],"effects":[56],"Blastocystis.":[61],"For":[62],"purpose,":[64],"anti-Blastocystis":[66,101,186],"activities":[67],"thymoquinone":[69],"(TQ)":[70],"capsaicin":[72],"(CAP)":[73],"were":[74],"evaluated":[75,108],"vitro.":[77],"isolate":[79],"was":[80,107,127,151,177],"inoculated":[81],"Jones":[83],"medium":[84],"1.5":[86],"mL":[87],"eppendorf":[88],"tubes":[89],"supplemented":[90],"fetal":[92],"calf":[93],"serum":[94],"(FCS)":[95],"incubated":[97],"at":[98],"37\u00b0C.":[99],"The":[100],"effect":[102,165],"TQ":[104,119,133,157,180],"CAP":[106,121,138,162],"by":[109],"light":[110],"microscopy":[111,116],"(LM)":[112],"scanning":[114],"electron":[115],"(SEM).":[117],"Both":[118],"had":[122,163],"anti":[123],"It":[126,176],"observed":[128,152],"500":[130],"ug/mL":[131,136],"1000":[135],"inhibited":[139],"100%":[140],"growth.":[143],"LM":[146],"SEM":[148],"images,":[149],"treated":[155],"decreased":[158],"size":[160],"on":[166],"cell":[168],"surface":[169],"when":[170],"compared":[171,188],"control":[174],"group.":[175],"concluded":[178],"could":[181],"be":[182,198],"a":[183],"more":[184,194],"reliable":[185],"MTZ":[190],"CAP,":[192],"but":[193],"comprehensive":[195],"studies":[196],"should":[197],"performed.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-06-04T00:00:00"}