{"id":"https://openalex.org/W4399201743","doi":"https://doi.org/10.21203/rs.3.rs-4384837/v1","title":"Surveillance of Antimicrobial resistance among organism causing Bacteremia in patients admitted in Mbarara Regional Referral Hospital, Mbarara, Southwestern Uganda","display_name":"Surveillance of Antimicrobial resistance among organism causing Bacteremia in patients admitted in Mbarara Regional Referral Hospital, Mbarara, Southwestern Uganda","publication_year":2024,"publication_date":"2024-05-31","ids":{"openalex":"https://openalex.org/W4399201743","doi":"https://doi.org/10.21203/rs.3.rs-4384837/v1"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-4384837/v1","doi":"https://doi.org/10.21203/rs.3.rs-4384837/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4384837/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.21203/rs.3.rs-4384837/v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050004367","display_name":"Joel Bazira","orcid":"https://orcid.org/0000-0001-7600-7514","observed_orcids":["https://orcid.org/0000-0001-7600-7514"]},"institutions":[{"id":"https://openalex.org/I141930137","display_name":"Mbarara University of Science and Technology","ror":"https://ror.org/01bkn5154","country_code":"UG","type":"education","lineage":["https://openalex.org/I141930137"]}],"countries":["UG"],"is_corresponding":true,"raw_author_name":"Joel bazira","raw_affiliation_strings":["Mbarara University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mbarara University of Science and Technology","institution_ids":["https://openalex.org/I141930137"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018454646","display_name":"Pauline Petra Nalumaga","orcid":"https://orcid.org/0009-0007-1264-4910","observed_orcids":["https://orcid.org/0009-0007-1264-4910"]},"institutions":[{"id":"https://openalex.org/I141930137","display_name":"Mbarara University of Science and Technology","ror":"https://ror.org/01bkn5154","country_code":"UG","type":"education","lineage":["https://openalex.org/I141930137"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Nalumaga Pauline Petra","raw_affiliation_strings":["Mbarara University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mbarara University of Science and Technology","institution_ids":["https://openalex.org/I141930137"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075807074","display_name":"Jacob Stanley Iramiot","orcid":"https://orcid.org/0000-0002-9239-6641","observed_orcids":["https://orcid.org/0000-0002-9239-6641"]},"institutions":[{"id":"https://openalex.org/I287756978","display_name":"Busitema University","ror":"https://ror.org/035d9jb31","country_code":"UG","type":"education","lineage":["https://openalex.org/I287756978"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Jacob Iramiot","raw_affiliation_strings":["Busitema University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Busitema University","institution_ids":["https://openalex.org/I287756978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098955773","display_name":"Baluku Kuraishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141930137","display_name":"Mbarara University of Science and Technology","ror":"https://ror.org/01bkn5154","country_code":"UG","type":"education","lineage":["https://openalex.org/I141930137"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Baluku Kuraishi","raw_affiliation_strings":["Mbarara University of Science and Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mbarara University of Science and Technology","institution_ids":["https://openalex.org/I141930137"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001033292","display_name":"Abel Wilson Walekhwa","orcid":"https://orcid.org/0000-0001-9690-4650","observed_orcids":["https://orcid.org/0000-0001-9690-4650"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Abel Walekhwa","raw_affiliation_strings":["University of Cambridge"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Cambridge","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058203404","display_name":"Derick Hope","orcid":"https://orcid.org/0000-0002-7775-1748","observed_orcids":["https://orcid.org/0000-0002-7775-1748"]},"institutions":[{"id":"https://openalex.org/I3132109944","display_name":"Muni University","ror":"https://ror.org/04wr6mz63","country_code":"UG","type":"education","lineage":["https://openalex.org/I3132109944"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Hope Derick","raw_affiliation_strings":["Muni University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Muni University","institution_ids":["https://openalex.org/I3132109944"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030383358","display_name":"Lawrence Mugisha","orcid":"https://orcid.org/0000-0003-4932-3356","observed_orcids":["https://orcid.org/0000-0003-4932-3356"]},"institutions":[{"id":"https://openalex.org/I72227227","display_name":"Makerere University","ror":"https://ror.org/03dmz0111","country_code":"UG","type":"education","lineage":["https://openalex.org/I72227227"]}],"countries":["UG"],"is_corresponding":false,"raw_author_name":"Lawrence Mugisha","raw_affiliation_strings":["Makerere University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Makerere University","institution_ids":["https://openalex.org/I72227227"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5050004367"],"corresponding_institution_ids":["https://openalex.org/I141930137"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.7943999767303467,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.7943999767303467,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.15119999647140503,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.02539999969303608,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.9739999771118164},{"id":"https://openalex.org/keywords/bacteremia","display_name":"bacteremia","score":0.9599999785423279},{"id":"https://openalex.org/keywords/bloodstream-infection","display_name":"bloodstream infection","score":0.9769999980926514},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9549999833106995},{"id":"https://openalex.org/keywords/gram-positive-bacteria","display_name":"Gram-positive bacteria","score":0.8009999990463257},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ceftriaxone-resistance","display_name":"ceftriaxone resistance","score":0.9789999723434448},{"id":"https://openalex.org/keywords/ampicillin-resistance","display_name":"ampicillin resistance","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antimicrobial-susceptibility-patterns","display_name":"antimicrobial susceptibility patterns","score":0.6899999976158142},{"id":"https://openalex.org/keywords/empirical-antibiotic-therapy","display_name":"empirical antibiotic therapy","score":0.8600000143051147},{"id":"https://openalex.org/keywords/mbarara-uganda","display_name":"Mbarara, Uganda","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C2779443120","wikidata":"https://www.wikidata.org/wiki/Q650912","display_name":"Bacteremia","level":3,"score":0.7504197359085083},{"id":"https://openalex.org/C2776135927","wikidata":"https://www.wikidata.org/wiki/Q5242559","display_name":"Referral","level":2,"score":0.7401501536369324},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6543973088264465},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.49507632851600647},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37531352043151855},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3279041051864624},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2819640338420868},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.2649688124656677},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.17548424005508423},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06825447082519531}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21203/rs.3.rs-4384837/v1","doi":"https://doi.org/10.21203/rs.3.rs-4384837/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4384837/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-4384837/v1","doi":"https://doi.org/10.21203/rs.3.rs-4384837/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4384837/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W26641785","https://openalex.org/W1501895899","https://openalex.org/W1872367053","https://openalex.org/W1980115510","https://openalex.org/W1981366484","https://openalex.org/W2014376165","https://openalex.org/W2038014125","https://openalex.org/W2040443954","https://openalex.org/W2048789388","https://openalex.org/W2087203965","https://openalex.org/W2088359912","https://openalex.org/W2100106336","https://openalex.org/W2122870532","https://openalex.org/W2129452342","https://openalex.org/W2168409658","https://openalex.org/W2311550304","https://openalex.org/W2564442660","https://openalex.org/W2586663647","https://openalex.org/W2782241387","https://openalex.org/W2794623497","https://openalex.org/W2895796856","https://openalex.org/W2913249397","https://openalex.org/W2921225068","https://openalex.org/W3011651479","https://openalex.org/W3036771796","https://openalex.org/W3048874793","https://openalex.org/W3091898281","https://openalex.org/W3108495270","https://openalex.org/W3162740820","https://openalex.org/W3164744071","https://openalex.org/W3169601472","https://openalex.org/W4205602907","https://openalex.org/W4235863568","https://openalex.org/W4247971812","https://openalex.org/W4295708924","https://openalex.org/W4385875320","https://openalex.org/W4389932972","https://openalex.org/W4391886795","https://openalex.org/W6903405491"],"related_works":["https://openalex.org/W4385875320","https://openalex.org/W3214325551","https://openalex.org/W4401251483","https://openalex.org/W2748706728","https://openalex.org/W4415652572","https://openalex.org/W4413055694","https://openalex.org/W4417200425","https://openalex.org/W4210745764","https://openalex.org/W2276831367","https://openalex.org/W4400422888"],"abstract_inverted_index":{"Abstract":[0],"Blood":[1],"stream":[2,205],"infections":[3,158,179],"are":[4,22],"the":[5,40,77,126,142,165,177,189,194,203,208],"major":[6],"cause":[7,29],"of":[8,10,18,30,42,61,73,80,87,96,104,112,122,135,188,202,232,247],"fevers":[9],"undetermined":[11],"origin":[12],"in":[13,45,109,147,161,176,235,242,250],"Africa.":[14],"The":[15],"continuing":[16],"emergence":[17,79],"pathogenic":[19],"microorganisms":[20],"that":[21,90],"resistant":[23,233],"to":[24,47,54,75,119,153,227],"first-line":[25],"antimicrobials":[26],"is":[27],"a":[28,50],"increasing":[31,216],"Anti-Microbial":[32],"Resistance":[33],"concern.":[34],"This":[35,83],"study":[36,84,143,167,228],"aimed":[37],"at":[38],"understanding":[39],"surveillance":[41],"antimicrobial":[43,62,81,229],"resistance":[44,63,217],"order":[46],"serve":[48],"as":[49],"quality":[51],"assurance":[52],"tool":[53],"determine":[55],"common":[56],"pathogens":[57,171,183],"causing":[58],"bacteremia,":[59],"trends":[60],"which":[64],"will":[65,239,256],"guide":[66],"drug-policy":[67],"decisions":[68],"and":[69,117,124,131,151,211,221,259],"facilitate":[70],"rational":[71],"use":[72],"drugs":[74],"prevent":[76],"further":[78],"resistance.":[82],"analyzed":[85,260],"results":[86],"blood":[88,204,236],"cultures":[89],"were":[91,145,159],"routinely":[92],"taken":[93],"from":[94,138],"patients":[95,107],"different":[97,110],"age":[98],"groups":[99],"with":[100],"fever":[101],"or":[102],"suspicion":[103],"sepsis":[105,249],"among":[106,219],"admitted":[108],"wards":[111],"Mbarara":[113,120],"Regional":[114],"Referral":[115],"Hospital":[116],"transported":[118],"University":[121],"Science":[123],"Technology,":[125],"microbiology":[127],"laboratory":[128,253],"between":[129],"2015":[130],"2022.":[132],"Bacterial":[133],"isolates":[134,238],"clinical":[136],"significance":[137],"specimens":[139],"received":[140],"during":[141],"period":[144],"recorded":[146],"WHONET":[148],"(surveillance":[149],"software)":[150],"exported":[152],"STATA":[154],"for":[155,173,185,199],"analysis.":[156],"Bloodstream":[157],"confirmed":[160,178],"259":[162],"cases":[163],"over":[164],"seven-year":[166],"period.":[168],"Gram":[169,209],"positive":[170,210],"accounted":[172,184],"160":[174],"(61.7%)":[175],"while":[180],"gram":[181,212],"negative":[182,213],"99":[186],"(38.2%)":[187],"cases.":[190],"Staphylococcus":[191],"aureus":[192],"was":[193],"most":[195],"isolated":[196],"pathogen":[197],"accounting":[198],"57.1%":[200],"(n=148)":[201],"infections.":[206],"Both":[207],"bacteria":[214,234],"demonstrated":[215],"towards":[218],"Ceftriaxone":[220],"Ampicillin.":[222],"Using":[223],"advanced":[224],"information":[225],"technology":[226],"susceptibility":[230],"patterns":[231],"culture":[237],"be":[240,257],"useful":[241],"directing":[243],"empiric":[244],"antibiotic":[245],"therapy":[246],"severe":[248],"Uganda":[251],"because":[252],"data":[254],"being":[255],"collected":[258],"rapidly.":[261]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2024-06-01T00:00:00"}
