{"id":"https://openalex.org/W4398210280","doi":"https://doi.org/10.1097/01.hjh.0001020632.96468.36","title":"LOW HIGH-DENSITY LIPOPROTEIN LEVEL PROMOTES INFLAMMATORY RESPONSE IN LONG COVID PATIENTS UNDERGOING HEMODIALYSIS ONE YEAR AFTER INFECTION","display_name":"LOW HIGH-DENSITY LIPOPROTEIN LEVEL PROMOTES INFLAMMATORY RESPONSE IN LONG COVID PATIENTS UNDERGOING HEMODIALYSIS ONE YEAR AFTER INFECTION","publication_year":2024,"publication_date":"2024-05-01","ids":{"openalex":"https://openalex.org/W4398210280","doi":"https://doi.org/10.1097/01.hjh.0001020632.96468.36"},"language":"en","primary_location":{"id":"doi:10.1097/01.hjh.0001020632.96468.36","doi":"https://doi.org/10.1097/01.hjh.0001020632.96468.36","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.hjh.0001020632.96468.36","pdf_url":null,"source":{"id":"https://openalex.org/S115964404","display_name":"Journal of Hypertension","issn_l":"0263-6352","issn":["0263-6352","1473-5598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hypertension","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067877860","display_name":"Natalia Stepanova","orcid":"https://orcid.org/0000-0002-1070-3602","observed_orcids":["https://orcid.org/0000-0002-1070-3602"]},"institutions":[{"id":"https://openalex.org/I4210085859","display_name":"Institute of Nephrology of the National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/000889019","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210085859","https://openalex.org/I4210144782","https://openalex.org/I4405285930"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Natalia Stepanova","raw_affiliation_strings":["State Institution Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, UKRAINE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Institution Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, UKRAINE","institution_ids":["https://openalex.org/I4210085859","https://openalex.org/I4210144782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111637602","display_name":"V. Driianska","orcid":"https://orcid.org/0000-0002-2586-5532","observed_orcids":["https://orcid.org/0000-0002-2586-5532"]},"institutions":[{"id":"https://openalex.org/I4210085859","display_name":"Institute of Nephrology of the National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/000889019","country_code":"UA","type":"facility","lineage":["https://openalex.org/I4210085859","https://openalex.org/I4210144782","https://openalex.org/I4405285930"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Victoria Driianska","raw_affiliation_strings":["State Institution Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, UKRAINE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Institution Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, UKRAINE","institution_ids":["https://openalex.org/I4210085859","https://openalex.org/I4210144782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066900734","display_name":"Andriy Rysyev","orcid":"https://orcid.org/0009-0008-0791-2631","observed_orcids":["https://orcid.org/0009-0008-0791-2631"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andriy Rysyev","raw_affiliation_strings":["Medical Center LLC Link-Medital, Odesa, UKRAINE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Center LLC Link-Medital, Odesa, UKRAINE","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022019705","display_name":"Lyudmyla Snisar","orcid":"https://orcid.org/0000-0002-2968-0885","observed_orcids":["https://orcid.org/0000-0002-2968-0885"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lyudmyla Snisar","raw_affiliation_strings":["Medical Center LLC Nephrocenter, Kyiv, UKRAINE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Center LLC Nephrocenter, Kyiv, UKRAINE","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034468538","display_name":"Daria Chernianu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daria Chernianu","raw_affiliation_strings":["Medical Center LLC Link-Medital, Odesa, UKRAINE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Center LLC Link-Medital, Odesa, UKRAINE","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"Suppl 1","first_page":"e130","last_page":"e130"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11892","display_name":"Kawasaki Disease and Coronary Complications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-covid","display_name":"long COVID","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.7919999957084656},{"id":"https://openalex.org/keywords/low-hdl-cholesterol","display_name":"low HDL cholesterol","score":0.9319999814033508},{"id":"https://openalex.org/keywords/high-density-lipoprotein","display_name":"high-density lipoprotein","score":0.878000020980835},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7070000171661377},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.8640000224113464},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9990000128746033},{"id":"https://openalex.org/keywords/il-17","display_name":"IL-17","score":1.0},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cardiovascular-complications","display_name":"cardiovascular complications","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.974529504776001},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.7314146757125854},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.6387410759925842},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.5654271841049194},{"id":"https://openalex.org/C3020196126","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammatory response","level":3,"score":0.5303871035575867},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5151978135108948},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4411117136478424},{"id":"https://openalex.org/C2909376813","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus Infections","level":5,"score":0.4150887131690979},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.35008978843688965},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3251795768737793},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.23531562089920044},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.06630578637123108},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.hjh.0001020632.96468.36","doi":"https://doi.org/10.1097/01.hjh.0001020632.96468.36","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.hjh.0001020632.96468.36","pdf_url":null,"source":{"id":"https://openalex.org/S115964404","display_name":"Journal of Hypertension","issn_l":"0263-6352","issn":["0263-6352","1473-5598"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hypertension","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4394926986","https://openalex.org/W4323820830","https://openalex.org/W4229063559","https://openalex.org/W4397041003","https://openalex.org/W4402692245","https://openalex.org/W4225538509","https://openalex.org/W4392292783","https://openalex.org/W4298140556","https://openalex.org/W3211177044","https://openalex.org/W4386242889"],"abstract_inverted_index":{"Objective:":[0],"Long":[1],"COVID,":[2,105],"a":[3,78,86,211],"syndrome":[4],"characterized":[5],"by":[6],"persistent":[7],"symptoms":[8],"post-acute":[9],"SARS-CoV-2":[10],"infection,":[11],"poses":[12],"unique":[13],"challenges":[14],"for":[15],"patients":[16,198,217,243],"undergoing":[17,247],"hemodialysis":[18,70],"(HD).":[19],"Low":[20],"levels":[21,163,183,226,236],"of":[22,68,81,88,188],"high-density":[23],"lipoprotein":[24],"(HDL)":[25],"(<1.2":[26,184],"mmol/L)":[27],"have":[28],"been":[29],"implicated":[30],"in":[31,39,57,92,195,216,242,277],"heightened":[32],"COVID-19":[33],"risk":[34],"and":[35,54,64,85,114,123,143,148,191,222,267,274],"associated":[36],"cardiovascular":[37,254],"complications":[38],"this":[40,93,265],"patient":[41],"population.":[42],"This":[43],"study":[44],"aimed":[45],"to":[46,165,197,271],"explore":[47],"the":[48,151,239,262],"potential":[49],"association":[50,266],"between":[51],"low":[52,181,224,234],"HDL":[53,162,182,200,225,235],"inflammatory":[55,115,214,240],"responses":[56],"long":[58,104,157,220,245,278],"COVID":[59,158,221,246,279],"among":[60,280],"HD":[61,248,281],"patients.":[62,282],"Design":[63],"method:":[65],"A":[66],"total":[67],"80":[69],"(HD)":[71],"patients,":[72],"aged":[73],"55":[74],"(44-62.5)":[75],"years,":[76],"with":[77,103,180,199,244],"dialysis":[79],"vintage":[80],"45":[82,99],"(21-78.6)":[83],"months":[84],"history":[87],"COVID-19,":[89],"were":[90,101,127,134,139,193],"enrolled":[91],"cross-sectional":[94],"cohort":[95],"study.":[96],"Among":[97,178],"them,":[98],"(56.2%)":[100],"diagnosed":[102],"while":[106],"35":[107],"(43.8%)":[108],"had":[109],"fully":[110,166],"recovered.":[111],"Lipid":[112],"profiles":[113],"markers,":[116],"such":[117],"as":[118,141],"serum":[119],"interleukin":[120],"(IL)-6,":[121],"IL-17,":[122],"C-reactive":[124],"protein":[125],"(CRP),":[126],"assessed":[128],"one":[129,249],"year":[130,250],"post-infection.":[131],"The":[132],"cytokines":[133],"measured":[135],"using":[136,150],"ELISA.":[137],"Data":[138],"presented":[140],"median":[142],"interquartile":[144],"interval":[145],"[Me":[146],"(Q25-Q75)]":[147],"compared":[149,164],"Mann-Whitney":[152],"test.":[153],"Results:":[154],"Patients":[155],"experiencing":[156,219],"exhibited":[159],"significantly":[160],"lower":[161],"recovered":[167],"individuals:":[168],"1.19":[169],"(1.06-1.76)":[170],"vs":[171],"1.66":[172],"(1.32-1.92)":[173],"mmol/L":[174,204],"(p":[175],"=":[176],"0.02).":[177],"those":[179],"mmol/L),":[185],"elevated":[186],"concentrations":[187,201],"CRP,":[189],"IL-6,":[190],"IL-17":[192],"evident":[194],"comparison":[196],"exceeding":[202],"1.2":[203],"(Fig.":[205,227],"1).":[206],"Subsequent":[207],"subgroup":[208],"analysis":[209],"revealed":[210],"more":[212],"pronounced":[213],"profile":[215],"concurrently":[218],"exhibiting":[223],"2).":[228],"Conclusions:":[229],"Our":[230],"findings":[231],"indicate":[232],"that":[233],"may":[237],"enhance":[238],"response":[241],"post-infection,":[251],"potentially":[252],"promoting":[253],"complications.":[255],"Future":[256],"research":[257],"should":[258],"focus":[259],"on":[260],"elucidating":[261],"pathways":[263],"underlying":[264],"exploring":[268],"novel":[269],"strategies":[270],"mitigate":[272],"inflammation":[273],"improve":[275],"outcomes":[276]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-23T00:00:00"}