{"id":"https://openalex.org/W4398141017","doi":"https://doi.org/10.3390/ijms25105514","title":"Bifidobacterium longum and Chlorella sorokiniana Combination Modulates IFN-\u03b3, IL-10, and SOCS3 in Rotavirus-Infected Cells","display_name":"Bifidobacterium longum and Chlorella sorokiniana Combination Modulates IFN-\u03b3, IL-10, and SOCS3 in Rotavirus-Infected Cells","publication_year":2024,"publication_date":"2024-05-18","ids":{"openalex":"https://openalex.org/W4398141017","doi":"https://doi.org/10.3390/ijms25105514","pmid":"https://pubmed.ncbi.nlm.nih.gov/38791551","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11122607"},"language":"en","primary_location":{"id":"doi:10.3390/ijms25105514","doi":"https://doi.org/10.3390/ijms25105514","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25105514","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4398141017"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/ijms25105514","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5098710687","display_name":"Felizardo Velderrain-Armenta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4061448","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34","country_code":"MX","type":"education","lineage":["https://openalex.org/I4061448"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Felizardo Velderrain-Armenta","raw_affiliation_strings":["Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico","institution_ids":["https://openalex.org/I4061448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013183407","display_name":"Guadalupe Gonz\u00e1lez-Ochoa","orcid":"https://orcid.org/0000-0001-5041-0786","observed_orcids":["https://orcid.org/0000-0001-5041-0786"]},"institutions":[{"id":"https://openalex.org/I4061448","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34","country_code":"MX","type":"education","lineage":["https://openalex.org/I4061448"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Guadalupe Gonz\u00e1lez-Ochoa","raw_affiliation_strings":["Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico","institution_ids":["https://openalex.org/I4061448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086031673","display_name":"Patricia Tamez\u2010Guerra","orcid":"https://orcid.org/0000-0002-4831-2340","observed_orcids":["https://orcid.org/0000-0002-4831-2340"]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Patricia Tamez-Guerra","raw_affiliation_strings":["Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-4831-2340","affiliations":[{"raw_affiliation_string":"Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060835964","display_name":"Ricardo Romero-Arg\u00fcelles","orcid":"https://orcid.org/0000-0002-6153-7835","observed_orcids":["https://orcid.org/0000-0002-6153-7835"]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ricardo Romero-Arguelles","raw_affiliation_strings":["Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-6153-7835","affiliations":[{"raw_affiliation_string":"Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062887322","display_name":"C\u00e9sar I. Romo-S\u00e1enz","orcid":"https://orcid.org/0000-0002-4013-8974","observed_orcids":["https://orcid.org/0000-0002-4013-8974"]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"C\u00e9sar I. Romo-S\u00e1enz","raw_affiliation_strings":["Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007892649","display_name":"Ricardo Gomez\u2010Flores","orcid":"https://orcid.org/0000-0002-9518-4433","observed_orcids":["https://orcid.org/0000-0002-9518-4433"]},"institutions":[{"id":"https://openalex.org/I169046204","display_name":"Universidad Aut\u00f3noma de Nuevo Le\u00f3n","ror":"https://ror.org/01fh86n78","country_code":"MX","type":"education","lineage":["https://openalex.org/I169046204"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ricardo Gomez-Flores","raw_affiliation_strings":["Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunology and Virology, Falculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicol\u00e1s de los Garza C.P. 66455, Mexico","institution_ids":["https://openalex.org/I169046204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033372094","display_name":"Lilian Karem Flores-Mendoza","orcid":"https://orcid.org/0000-0002-6490-1364","observed_orcids":["https://orcid.org/0000-0002-6490-1364"]},"institutions":[{"id":"https://openalex.org/I4061448","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34","country_code":"MX","type":"education","lineage":["https://openalex.org/I4061448"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Lilian Flores-Mendoza","raw_affiliation_strings":["Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico","institution_ids":["https://openalex.org/I4061448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084527636","display_name":"Ramona Icedo-Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4061448","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34","country_code":"MX","type":"education","lineage":["https://openalex.org/I4061448"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ramona Icedo-Garc\u00eda","raw_affiliation_strings":["Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico","institution_ids":["https://openalex.org/I4061448"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071118917","display_name":"Jos\u00e9 G. So\u00f1anez\u2010Organis","orcid":"https://orcid.org/0000-0002-8742-3262","observed_orcids":["https://orcid.org/0000-0002-8742-3262"]},"institutions":[{"id":"https://openalex.org/I4061448","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34","country_code":"MX","type":"education","lineage":["https://openalex.org/I4061448"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 G. So\u00f1anez-Organis","raw_affiliation_strings":["Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry-Biology and Agriculture, Interdisciplinary Faculty of Biology Sciences and Health, University of Sonora, Navojoa C.P. 85880, Mexico","institution_ids":["https://openalex.org/I4061448"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5013183407","https://openalex.org/A5086031673"],"corresponding_institution_ids":["https://openalex.org/I169046204","https://openalex.org/I4061448"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3296},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3296},"fwci":0.9833,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.69628283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"25","issue":"10","first_page":"5514","last_page":"5514"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9204000234603882,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9204000234603882,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.01269999984651804,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bifidobacterium-longum","display_name":"Bifidobacterium longum","score":0.9869999885559082},{"id":"https://openalex.org/keywords/chlorella-sorokiniana","display_name":"Chlorella sorokiniana","score":1.0},{"id":"https://openalex.org/keywords/rotavirus","display_name":"rotavirus","score":0.7850000262260437},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.9549999833106995},{"id":"https://openalex.org/keywords/antiviral-immunity","display_name":"antiviral immunity","score":0.7910000085830688},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.972000002861023},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9990000128746033},{"id":"https://openalex.org/keywords/socs3","display_name":"SOCS3","score":1.0},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.996999979019165},{"id":"https://openalex.org/keywords/stat2","display_name":"STAT2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-i-interferon","display_name":"type I interferon","score":0.8009999990463257},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.8450000286102295},{"id":"https://openalex.org/keywords/viral-gastroenteritis","display_name":"viral gastroenteritis","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C2776996202","wikidata":"https://www.wikidata.org/wiki/Q4904768","display_name":"Bifidobacterium longum","level":5,"score":0.8776057958602905},{"id":"https://openalex.org/C2779375934","wikidata":"https://www.wikidata.org/wiki/Q19596359","display_name":"Chlorella sorokiniana","level":4,"score":0.8197830319404602},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7044002413749695},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6357499361038208},{"id":"https://openalex.org/C2781367151","wikidata":"https://www.wikidata.org/wiki/Q164778","display_name":"Rotavirus","level":3,"score":0.6035373210906982},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5373780727386475},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5062457919120789},{"id":"https://openalex.org/C2781154746","wikidata":"https://www.wikidata.org/wiki/Q1431408","display_name":"Neospora caninum","level":4,"score":0.4195854663848877},{"id":"https://openalex.org/C2780305828","wikidata":"https://www.wikidata.org/wiki/Q132656","display_name":"Bifidobacterium","level":4,"score":0.3438403010368347},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.2750239968299866},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24307331442832947},{"id":"https://openalex.org/C2778128430","wikidata":"https://www.wikidata.org/wiki/Q131003","display_name":"Toxoplasma gondii","level":3,"score":0.143997460603714},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.13250887393951416},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.07380473613739014},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C2781144631","wikidata":"https://www.wikidata.org/wiki/Q133017","display_name":"Chlorella","level":3,"score":0.0},{"id":"https://openalex.org/C559758991","wikidata":"https://www.wikidata.org/wiki/Q37868","display_name":"Algae","level":2,"score":0.0},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000069978","descriptor_name":"Bifidobacterium longum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071223","descriptor_name":"Suppressor of Cytokine Signaling 3 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002708","descriptor_name":"Chlorella","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012400","descriptor_name":"Rotavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D012401","descriptor_name":"Rotavirus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019073","descriptor_name":"HT29 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D050794","descriptor_name":"STAT1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3390/ijms25105514","doi":"https://doi.org/10.3390/ijms25105514","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25105514","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11122607","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11122607","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11122607/pdf/ijms-25-05514.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:38791551","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38791551","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/ijms25105514","doi":"https://doi.org/10.3390/ijms25105514","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms25105514","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3221571929","display_name":null,"funder_award_id":"USO513006130","funder_id":"https://openalex.org/F4320326407","funder_display_name":"Universidad de Sonora"},{"id":"https://openalex.org/G5888738330","display_name":null,"funder_award_id":"16614","funder_id":"https://openalex.org/F4320336053","funder_display_name":"Sistema Nacional de Investigadores"},{"id":"https://openalex.org/G5982780797","display_name":null,"funder_award_id":"SNII-9942","funder_id":"https://openalex.org/F4320321739","funder_display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda"},{"id":"https://openalex.org/G6636051521","display_name":null,"funder_award_id":"SNII-16614","funder_id":"https://openalex.org/F4320321739","funder_display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda"},{"id":"https://openalex.org/G6923087729","display_name":null,"funder_award_id":"16614","funder_id":"https://openalex.org/F4320321739","funder_display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda"},{"id":"https://openalex.org/G7032624841","display_name":null,"funder_award_id":"USO513007912","funder_id":"https://openalex.org/F4320326407","funder_display_name":"Universidad de Sonora"},{"id":"https://openalex.org/G928410869","display_name":null,"funder_award_id":"USO513006130 and USO513007912","funder_id":"https://openalex.org/F4320326407","funder_display_name":"Universidad de Sonora"}],"funders":[{"id":"https://openalex.org/F4320321739","display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","ror":"https://ror.org/059ex5q34"},{"id":"https://openalex.org/F4320326407","display_name":"Universidad de Sonora","ror":"https://ror.org/00c32gy34"},{"id":"https://openalex.org/F4320336053","display_name":"Sistema Nacional de Investigadores","ror":"https://ror.org/02h3fqt03"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4398141017.pdf","grobid_xml":"https://content.openalex.org/works/W4398141017.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1566810327","https://openalex.org/W1908103064","https://openalex.org/W1970880532","https://openalex.org/W1980273154","https://openalex.org/W1989678448","https://openalex.org/W1997477860","https://openalex.org/W2001275070","https://openalex.org/W2011837553","https://openalex.org/W2028484557","https://openalex.org/W2047915395","https://openalex.org/W2048510645","https://openalex.org/W2059952282","https://openalex.org/W2086551357","https://openalex.org/W2096372976","https://openalex.org/W2107851344","https://openalex.org/W2109847101","https://openalex.org/W2114918609","https://openalex.org/W2129783463","https://openalex.org/W2135573034","https://openalex.org/W2139133827","https://openalex.org/W2141143436","https://openalex.org/W2175122451","https://openalex.org/W2187056800","https://openalex.org/W2333230870","https://openalex.org/W2596232252","https://openalex.org/W2617139746","https://openalex.org/W2787293545","https://openalex.org/W2892787249","https://openalex.org/W2896180430","https://openalex.org/W2931761017","https://openalex.org/W2952207780","https://openalex.org/W2960816097","https://openalex.org/W2970278391","https://openalex.org/W3005336214","https://openalex.org/W3025225937","https://openalex.org/W3164118705","https://openalex.org/W3203259152","https://openalex.org/W4214842595","https://openalex.org/W4214848203","https://openalex.org/W4224301478","https://openalex.org/W4224322688","https://openalex.org/W4283808127","https://openalex.org/W4283836502","https://openalex.org/W4293194480","https://openalex.org/W4306949646","https://openalex.org/W4308568638","https://openalex.org/W4318485532","https://openalex.org/W4375865868"],"related_works":["https://openalex.org/W4375865868","https://openalex.org/W3111803417","https://openalex.org/W2461711386","https://openalex.org/W3006927875","https://openalex.org/W2941917299","https://openalex.org/W789199676","https://openalex.org/W2091000580","https://openalex.org/W2333230870","https://openalex.org/W2903848779"],"abstract_inverted_index":{"Rotavirus":[0],"is":[1],"the":[2,59,69,88,141,150],"main":[3],"cause":[4],"of":[5,14,34,61,92,143,170],"acute":[6],"diarrhea":[7],"in":[8,83,107],"children":[9],"up":[10],"to":[11,23,57],"five":[12],"years":[13],"age.":[15],"In":[16,113],"this":[17],"regard,":[18],"probiotics":[19],"are":[20],"commonly":[21],"used":[22,129],"treat":[24],"or":[25,106,179],"prevent":[26],"gastroenteritis":[27],"including":[28],"viral":[29,42],"infections.":[30],"The":[31,53,168],"anti-rotavirus":[32],"effect":[33,60],"Bifidobacterium":[35],"longum":[36,63,101,121,145],"and":[37,44,80,102,133,146,158,166,187],"Chlorella":[38],"sorokiniana,":[39,178],"by":[40,75,110,135,155,163],"reducing":[41],"infectivity":[43],"improving":[45],"IFN-type":[46],"I":[47],"response,":[48],"has":[49],"been":[50],"previously":[51],"reported.":[52],"present":[54],"study":[55,58,172],"aimed":[56],"B.":[62,100,120,144,175],"and/or":[64,122],"C.":[65,103,123,147,177],"sorokiniana":[66,104,148],"on":[67],"modulating":[68],"antiviral":[70,151,183],"cellular":[71,152,184],"immune":[72,153,185],"response":[73,154,186],"mediated":[74],"IFN-\u03b3,":[76],"IL-10,":[77],"SOCS3,":[78],"STAT1,":[79],"STAT2":[81],"genes":[82],"rotavirus-infected":[84],"cells.":[85],"To":[86],"determine":[87],"mRNA":[89],"relative":[90],"expression":[91],"these":[93],"genes,":[94],"HT-29":[95],"cells":[96,116],"were":[97,117],"treated":[98,118],"with":[99,119],"alone":[105],"combination,":[108],"followed":[109],"rotavirus":[111],"infection.":[112],"addition,":[114],"infected":[115],"sorokiniana.":[124],"Cellular":[125],"RNA":[126],"was":[127],"purified,":[128],"for":[130],"cDNA":[131],"synthesis,":[132],"amplified":[134],"qPCR.":[136],"Our":[137],"results":[138,169],"demonstrated":[139],"that":[140,174],"combination":[142,181],"stimulates":[149],"upregulating":[156,164],"IFN-\u03b3":[157],"may":[159],"block":[160],"pro-inflammatory":[161,190],"cytokines":[162],"IL-10":[165],"SOCS3.":[167],"our":[171],"indicated":[173],"longum,":[176],"their":[180],"improve":[182],"might":[188],"modulate":[189],"responses.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2024-05-21T00:00:00"}