{"id":"https://openalex.org/W4397046321","doi":"https://doi.org/10.1681/asn.20223311s1913a","title":"Association Between Carotid Artery Plaque and Albuminuria in Individuals With Type 2 Diabetes and No Clinical Cardiovascular Disease","display_name":"Association Between Carotid Artery Plaque and Albuminuria in Individuals With Type 2 Diabetes and No Clinical Cardiovascular Disease","publication_year":2022,"publication_date":"2022-11-01","ids":{"openalex":"https://openalex.org/W4397046321","doi":"https://doi.org/10.1681/asn.20223311s1913a"},"language":"en","primary_location":{"id":"doi:10.1681/asn.20223311s1913a","doi":"https://doi.org/10.1681/asn.20223311s1913a","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.20223311s1913a","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072589219","display_name":"Luis Felipe Ferreira-Divino","orcid":"https://orcid.org/0000-0002-9258-1732","observed_orcids":["https://orcid.org/0000-0002-9258-1732"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Luis Felipe Ferreira-Divino","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069948018","display_name":"Viktor Rotbain Curovic","orcid":"https://orcid.org/0000-0002-4270-6701","observed_orcids":["https://orcid.org/0000-0002-4270-6701"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Viktor Rotbain Curovic","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040024539","display_name":"Christina Poulsen","orcid":"https://orcid.org/0000-0002-4355-3081","observed_orcids":["https://orcid.org/0000-0002-4355-3081"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Christina G. Poulsen","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030172497","display_name":"L\u00e6rke Urbak","orcid":"https://orcid.org/0000-0001-9539-1179","observed_orcids":["https://orcid.org/0000-0001-9539-1179"]},"institutions":[{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"L\u00e6rke Urbak","raw_affiliation_strings":["Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074649341","display_name":"Nete Tofte","orcid":"https://orcid.org/0000-0002-5331-9168","observed_orcids":["https://orcid.org/0000-0002-5331-9168"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Nete Tofte","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014215631","display_name":"Marie Frimodt\u2010M\u00f8ller","orcid":"https://orcid.org/0000-0002-8486-1515","observed_orcids":["https://orcid.org/0000-0002-8486-1515"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Marie Frimodt-Moller","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079493976","display_name":"Nikolaj Eldrup","orcid":"https://orcid.org/0000-0002-7980-5295","observed_orcids":["https://orcid.org/0000-0002-7980-5295"]},"institutions":[{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Nikolaj Eldrup","raw_affiliation_strings":["Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016588114","display_name":"Tine W. Hansen","orcid":"https://orcid.org/0000-0003-2274-0352","observed_orcids":["https://orcid.org/0000-0003-2274-0352","https://orcid.org/0000-0003-3241-047X"]},"institutions":[{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Tine Hansen","raw_affiliation_strings":["Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001628967","display_name":"Henrik Hegaard Sillesen","orcid":"https://orcid.org/0000-0002-3302-6288","observed_orcids":["https://orcid.org/0000-0002-3302-6288"]},"institutions":[{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Henrik H. Sillesen","raw_affiliation_strings":["Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085592050","display_name":"Peter R Rossing","orcid":"https://orcid.org/0000-0002-1531-4294","observed_orcids":["https://orcid.org/0000-0002-1531-4294","https://orcid.org/0009-0004-5073-0009"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I4405255865","display_name":"Steno Diabetes Center Copenhagen","ror":"https://ror.org/03gqzdg87","country_code":"DK","type":"funder","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385","https://openalex.org/I4405255865"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Peter Rossing","raw_affiliation_strings":["Kobenhavns Universitet, Kobenhavn, Denmark","Steno Diabetes Center Copenhagen, Herlev, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kobenhavns Universitet, Kobenhavn, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Steno Diabetes Center Copenhagen, Herlev, Denmark","institution_ids":["https://openalex.org/I4405255865"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":"11S","first_page":"913","last_page":"913"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9663000106811523,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.02669999934732914,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/albuminuria","display_name":"albuminuria","score":0.9860000014305115},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.972000002861023},{"id":"https://openalex.org/keywords/subclinical-atherosclerosis","display_name":"subclinical atherosclerosis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.7720000147819519},{"id":"https://openalex.org/keywords/urinary-albumin-excretion-rate","display_name":"urinary albumin excretion rate","score":0.7509999871253967},{"id":"https://openalex.org/keywords/albumin-creatinine-ratio","display_name":"albumin-creatinine ratio","score":0.8830000162124634},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.49000000953674316},{"id":"https://openalex.org/keywords/diabetic-vascular-disease","display_name":"diabetic vascular disease","score":0.546999990940094},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":0.6899999976158142},{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"diabetic retinopathy","score":0.5830000042915344},{"id":"https://openalex.org/keywords/diabetic-neuropathy","display_name":"diabetic neuropathy","score":0.7059999704360962},{"id":"https://openalex.org/keywords/diabetic-cardiomyopathy","display_name":"diabetic cardiomyopathy","score":0.5239999890327454},{"id":"https://openalex.org/keywords/diabetic-osteoporosis","display_name":"diabetic osteoporosis","score":0.32899999618530273}],"concepts":[{"id":"https://openalex.org/C2776174234","wikidata":"https://www.wikidata.org/wiki/Q974792","display_name":"Albuminuria","level":3,"score":0.9076777696609497},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7955648899078369},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6834101676940918},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6414728164672852},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5776826739311218},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5627914071083069},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5429745316505432},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5362222790718079},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.4644916355609894},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.4457293152809143},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.24951454997062683},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0663759708404541},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1681/asn.20223311s1913a","doi":"https://doi.org/10.1681/asn.20223311s1913a","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.20223311s1913a","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2051098568","https://openalex.org/W2117731929","https://openalex.org/W1986731158","https://openalex.org/W2380374668","https://openalex.org/W2013389081","https://openalex.org/W4397046284","https://openalex.org/W2042573788","https://openalex.org/W2996453574","https://openalex.org/W7168398709","https://openalex.org/W2370357836"],"abstract_inverted_index":{"Background:":[0],"The":[1,67,155],"association":[2,18],"between":[3,19,125],"albuminuria":[4,25,106,112,120,130,216,226,249,289],"and":[5,24,30,43,55,117,129,151,177,193,204],"subclinical":[6,300],"atherosclerosis":[7],"in":[8,26,46,77,257],"type":[9],"2":[10],"diabetes":[11,140,170],"(T2D)":[12],"remains":[13],"unclear.":[14],"We":[15],"investigated":[16],"the":[17,39,64,70,78,211,235],"carotid":[20,65,190,221,254,294],"artery":[21],"plaque":[22,72,127,191,222,255,295],"thickness":[23,73,128,256],"individuals":[27,52,188,280],"with":[28,53,69,133,219,253,281,293],"T2D":[29,54,282],"no":[31,56,284],"clinical":[32,57,285],"cardiovascular":[33],"disease":[34,45],"(CVD)":[35],"to":[36,224,275],"better":[37],"understand":[38],"pathophysiology":[40],"of":[41,63,93,96,101,163,172,185,288,299],"renal":[42],"vascular":[44],"T2D.":[47],"Methods:":[48],"In":[49,210,279],"total,":[50],"500":[51],"CVD":[58],"underwent":[59],"2-dimensional":[60],"ultrasound":[61],"scans":[62],"arteries.":[66],"side":[68],"highest":[71,126],"(mm)":[74],"was":[75,131,217,237,250,290],"included":[76,137],"analyses.":[79],"Albuminuria":[80],"measurements":[81,100],"were":[82,88,181],"available":[83],"for":[84],"466":[85],"individuals,":[86],"who":[87],"stratified":[89],"based":[90],"on":[91],"history":[92],"two":[94,178],"out":[95],"three":[97],"consecutively":[98],"recorded":[99],"UAER":[102],"or":[103,108,115,122],"UACR;":[104],"normal":[105,197,225,276],"(<30mg/24h":[107],"mg/g),":[109],"moderately":[110,201,214],"increased":[111,119,202,208,215,248],"(30-299":[113],"mg/24h":[114],"mg/g)":[116],"severely":[118,207],"(\u2265300mg/24h":[121],"mg/g).":[123],"Association":[124],"analyzed":[132],"linear":[134],"regression.":[135],"Adjustments":[136],"sex,":[138],"age,":[139],"duration,":[141],"systolic":[142],"blood":[143],"pressure,":[144],"eGFR,":[145],"LDL-cholesterol,":[146],"body":[147],"mass":[148],"index,":[149],"smoking,":[150],"statin":[152],"treatment.":[153],"Results:":[154],"study":[156],"population":[157],"had":[158,189,196],"a":[159,168,297],"mean":[160,169],"(\u00b1SD)":[161],"age":[162],"65":[164],"\u00b1":[165,174],"9":[166],"years,":[167,176],"duration":[171],"14":[173],"8":[175],"thirds":[179],"(67%)":[180],"males.":[182],"A":[183],"total":[184],"357":[186],"(71%)":[187],"(>1.5mm),":[192],"351":[194],"(75%)":[195],"albuminuria,":[198,203],"87":[199],"(19%)":[200],"28":[205],"(6%)":[206],"albuminuria.":[209,277],"unadjusted":[212,259],"analysis,":[213],"associated":[218,252,292],"thicker":[220],"compared":[223,274],"(0.27":[227],"mm,":[228,242,261],"95%CI:":[229],"(0.02":[230],"-":[231,244,263,270],"0.51);":[232],"p=0.03),":[233],"however,":[234],"significance":[236],"lost":[238],"after":[239],"adjustment":[240],"(0.13":[241],"(-0.13":[243],"0.38);":[245],"p=0.34).":[246],"Severely":[247],"not":[251,291],"neither":[258],"(0.35":[260],"(-0.04":[262],"0.75);":[264],"p=0.08)":[265],"nor":[266],"adjusted":[267],"(0.01mm,":[268],"(-0.35":[269],"0.50);":[271],"p=0.74)":[272],"models":[273],"Conclusions:":[278],"but":[283],"CVD,":[286],"presence":[287],"thickness,":[296],"measure":[298],"CVD.":[301]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2024-05-19T00:00:00"}
