{"id":"https://openalex.org/W4396992843","doi":"https://doi.org/10.1681/asn.20213210s1712b","title":"Impact of Race/Ethnicity and Age on Survival in Advanced CKD Patients Treated with Conservative Management vs. Dialysis","display_name":"Impact of Race/Ethnicity and Age on Survival in Advanced CKD Patients Treated with Conservative Management vs. Dialysis","publication_year":2021,"publication_date":"2021-10-01","ids":{"openalex":"https://openalex.org/W4396992843","doi":"https://doi.org/10.1681/asn.20213210s1712b"},"language":"en","primary_location":{"id":"doi:10.1681/asn.20213210s1712b","doi":"https://doi.org/10.1681/asn.20213210s1712b","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1681/asn.20213210s1712b","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002706590","display_name":"Amy Seungsook You","orcid":"https://orcid.org/0000-0002-2916-117X","observed_orcids":["https://orcid.org/0000-0002-2916-117X"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy S. You","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047313234","display_name":"Kamyar Kalantar\u2010Zadeh","orcid":"https://orcid.org/0000-0002-8666-0725","observed_orcids":["https://orcid.org/0000-0002-8666-0725"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kamyar Kalantar-Zadeh","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057070330","display_name":"Yoko Narasaki","orcid":"https://orcid.org/0000-0002-2571-3803","observed_orcids":["https://orcid.org/0000-0002-2571-3803"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoko Narasaki","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074587712","display_name":"Csaba Pal Kovesdy","orcid":"https://orcid.org/0000-0002-8204-911X","observed_orcids":["https://orcid.org/0000-0002-8204-911X"]},"institutions":[{"id":"https://openalex.org/I160606119","display_name":"University of Tennessee Health Science Center","ror":"https://ror.org/0011qv509","country_code":"US","type":"education","lineage":["https://openalex.org/I160606119"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Csaba P. Kovesdy","raw_affiliation_strings":["The University of Tennessee Health Science Center, Memphis, TN;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Tennessee Health Science Center, Memphis, TN;","institution_ids":["https://openalex.org/I160606119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053936326","display_name":"Dana B. Mukamel","orcid":"https://orcid.org/0000-0003-4147-5785","observed_orcids":["https://orcid.org/0000-0003-4147-5785"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana B. Mukamel","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054772288","display_name":"Susan T. Crowley","orcid":"https://orcid.org/0000-0001-8143-5759","observed_orcids":["https://orcid.org/0000-0001-8143-5759"]},"institutions":[{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan T. Crowley","raw_affiliation_strings":["Veterans Health Administration, Washington, DC","Yale University School of Medicine, New Haven, CT;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterans Health Administration, Washington, DC","institution_ids":["https://openalex.org/I2799886695"]},{"raw_affiliation_string":"Yale University School of Medicine, New Haven, CT;","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098358189","display_name":"Alejandra Novoa-Vargas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alejandra Novoa-Vargas","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055319271","display_name":"Danh V. Nguyen","orcid":"https://orcid.org/0000-0002-4025-8239","observed_orcids":["https://orcid.org/0000-0002-4025-8239"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danh V. Nguyen","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044034699","display_name":"Connie M. Rhee","orcid":"https://orcid.org/0000-0002-9703-6469","observed_orcids":["https://orcid.org/0000-0002-9703-6469"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Connie Rhee","raw_affiliation_strings":["University of California Irvine, Irvine, CA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Irvine, Irvine, CA;","institution_ids":["https://openalex.org/I204250578"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"10S","first_page":"712","last_page":"712"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10177","display_name":"Palliative Care and End-of-Life Issues","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.009399999864399433,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-chronic-kidney-disease","display_name":"advanced chronic kidney disease","score":0.9729999899864197},{"id":"https://openalex.org/keywords/conservative-treatment","display_name":"conservative treatment","score":0.9800000190734863},{"id":"https://openalex.org/keywords/dialysis","display_name":"dialysis","score":0.9020000100135803},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9359999895095825},{"id":"https://openalex.org/keywords/racial-and-ethnic-disparities","display_name":"racial and ethnic disparities","score":0.7630000114440918},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.8610000014305115},{"id":"https://openalex.org/keywords/timing-of-dialysis-initiation","display_name":"dialysis initiation timing","score":0.8610000014305115},{"id":"https://openalex.org/keywords/end-of-life-care","display_name":"end-of-life care","score":0.5590000152587891},{"id":"https://openalex.org/keywords/treatment-selection","display_name":"treatment selection","score":0.3059999942779541}],"concepts":[{"id":"https://openalex.org/C76509639","wikidata":"https://www.wikidata.org/wiki/Q918036","display_name":"Race (biology)","level":2,"score":0.7706714868545532},{"id":"https://openalex.org/C137403100","wikidata":"https://www.wikidata.org/wiki/Q41710","display_name":"Ethnic group","level":2,"score":0.7463654279708862},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.7338921427726746},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7183165550231934},{"id":"https://openalex.org/C2780904754","wikidata":"https://www.wikidata.org/wiki/Q25104748","display_name":"Conservative management","level":2,"score":0.621180534362793},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.5234465003013611},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4407581388950348},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41122978925704956},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.33589524030685425},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2206236720085144},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.08374068140983582},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0689869225025177},{"id":"https://openalex.org/C107993555","wikidata":"https://www.wikidata.org/wiki/Q1662673","display_name":"Gender studies","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1681/asn.20213210s1712b","doi":"https://doi.org/10.1681/asn.20213210s1712b","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1681/asn.20213210s1712b","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.7317000031471252,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4396991690","https://openalex.org/W4397045408","https://openalex.org/W4396990514","https://openalex.org/W4397040861","https://openalex.org/W4396988938","https://openalex.org/W4397025261","https://openalex.org/W2019007701","https://openalex.org/W2618343618","https://openalex.org/W4252779133","https://openalex.org/W2898323495"],"abstract_inverted_index":{"Background:":[0],"Given":[1],"evidence":[2],"that":[3],"dialysis":[4,46,85,127,139,158,166,173,186,198,217,235,252,274,301],"may":[5],"not":[6,137],"offer":[7],"survival":[8,248],"benefit":[9,249],"nor":[10],"improved":[11],"quality":[12],"of":[13,43,63,126,142,157,264,298],"life":[14],"in":[15,24,79,183,205,212,254],"certain":[16],"groups":[17,253],"(elderly,":[18],"multi-morbid),":[19],"there":[20],"is":[21,38,284],"growing":[22],"interest":[23],"conservative":[25],"management":[26],"(CM)":[27],"as":[28,113,115,131,161],"an":[29],"alternative":[30],"treatment":[31],"strategy":[32],"for":[33,107],"advanced":[34,65],"CKD.":[35],"Yet":[36],"little":[37],"known":[39],"about":[40],"the":[41,89,143,150],"impact":[42],"CM":[44,83,184,204,215,232,246,272,299],"vs.":[45,84,128,135,164,170,185,233,250,273,300],"on":[47,275],"CKD":[48,66,265],"outcomes,":[49],"including":[50,99],"mortality,":[51],"across":[52,188,208,222,278],"different":[53],"racial/ethnic":[54],"and":[55,101,104,109,190,196,216,229,280,291,296],"age":[56,210],"groups.":[57],"Methods:":[58],"In":[59,225,258],"a":[60,259,304],"national":[61],"cohort":[62,263],"309,188":[64],"patients":[67,80,187,214],"(\u22652":[68],"eGFRs":[69],"<25":[70],"separated":[71],"by":[72],"\u226590":[73],"days),":[74],"we":[75,267],"compared":[76],"mortality":[77,181,201,220,238,276],"rates":[78,182,202,221,239,277],"treated":[81],"with":[82,149],"from":[86,88],"1/1/07-6/30/20":[87],"OptumLabs\u00ae":[90],"Data":[91],"Warehouse":[92],"(OLDW),":[93],"which":[94,288],"contains":[95],"de-identified":[96],"administrative":[97],"claims,":[98],"medical":[100],"pharmacy":[102],"claims":[103],"enrollment":[105],"records":[106],"commercial":[108],"Medicare":[110],"Advantage":[111],"enrollees":[112],"well":[114],"electronic":[116],"health":[117,292],"record":[118],"data.":[119],"Patients":[120],"were":[121],"categorized":[122],"according":[123,154],"to":[124,155,179,286,302],"receipt":[125],"CM,":[129],"defined":[130,160],"those":[132,241],"who":[133],"did":[134,136],"receive":[138],"within":[140],"2-yrs":[141],"index":[144],"eGFR":[145,147],"(1st":[146],"<25),":[148],"former":[151],"group":[152],"parsed":[153],"timing":[156],"initiation,":[159],"late,":[162,194],"intermediate,":[163,195],"early":[165,197],"(eGFRs":[167],"<5,":[168],"5-<10,":[169],"\u226510":[171],"at":[172],"transition).":[174],"We":[175],"used":[176],"Poisson":[177],"regression":[178],"compare":[180],"race/ethnicity":[189,279],"age.":[191,281],"Results:":[192],"Whereas":[193],"had":[199,218,236],"higher":[200],"than":[203],"Non-Hispanic":[206,226],"Whites":[207],"all":[209,223,251],"groups,":[211],"Hispanic":[213],"similar":[219,237],"ages.":[224,256],"Blacks,":[227],"Asians,":[228],"Other":[230],"races/ethnicities,":[231],"late":[234],"among":[240],"\u226575":[242],"yrs":[243],"old,":[244],"whereas":[245],"demonstrated":[247],"younger":[255],"Conclusions:":[257],"diverse,":[260],"nationally":[261],"representative":[262],"patients,":[266],"observed":[268],"differential":[269],"relationships":[270],"between":[271],"Further":[282],"research":[283],"needed":[285],"determine":[287],"patient":[289],"characteristics":[290],"services":[293],"optimize":[294],"candidacy":[295],"choice":[297],"enable":[303],"personalized":[305],"approach.":[306],"Funding:":[307],"NIDDK":[308],"Support":[309]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2024-05-18T00:00:00"}