{"id":"https://openalex.org/W4396977968","doi":"https://doi.org/10.1093/bjd/ljae194","title":"Downregulation of lysine 2-hydroxyisobutyrylation of ErbB3 binding protein 1 at amino acid 210 promotes keratinocyte proliferation via induction of transcription initiation factor IA-mediated rRNA synthesis","display_name":"Downregulation of lysine 2-hydroxyisobutyrylation of ErbB3 binding protein 1 at amino acid 210 promotes keratinocyte proliferation via induction of transcription initiation factor IA-mediated rRNA synthesis","publication_year":2024,"publication_date":"2024-05-16","ids":{"openalex":"https://openalex.org/W4396977968","doi":"https://doi.org/10.1093/bjd/ljae194","pmid":"https://pubmed.ncbi.nlm.nih.gov/38752336"},"language":"en","primary_location":{"id":"doi:10.1093/bjd/ljae194","doi":"https://doi.org/10.1093/bjd/ljae194","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bjd/ljae194","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/bjd/ljae194","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101847442","display_name":"Junqin Li","orcid":"https://orcid.org/0000-0003-1507-366X","observed_orcids":["https://orcid.org/0000-0003-1507-366X"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junqin Li","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ying Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Wang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103595646","display_name":"Xuping Niu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuping Niu","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079863268","display_name":"Jianxiao Xing","orcid":"https://orcid.org/0000-0003-2980-2704","observed_orcids":["https://orcid.org/0000-0003-2980-2704"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxiao Xing","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108145094","display_name":"Yu Dou","orcid":"https://orcid.org/0009-0000-7132-3817","observed_orcids":["https://orcid.org/0009-0000-7132-3817"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Dou","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006561445","display_name":"Yuanjun Yao","orcid":"https://orcid.org/0009-0006-3709-0216","observed_orcids":["https://orcid.org/0009-0006-3709-0216","https://orcid.org/0000-0003-3477-420X"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanjun Yao","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101380600","display_name":"Yanyang Liang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanyang Liang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zehong Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zehong Wang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100367064","display_name":"Qiang Wang","orcid":"https://orcid.org/0000-0003-2614-9201","observed_orcids":["https://orcid.org/0000-0003-2614-9201"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Wang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100298950","display_name":"Feng Haiyan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiyan Feng","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Aihong Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aihong Peng","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102547873","display_name":"Yi Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Guo","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103189612","display_name":"Huifang Liang","orcid":"https://orcid.org/0000-0001-6874-3634","observed_orcids":["https://orcid.org/0000-0001-6874-3634"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huifang Liang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yaxin Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaxin Guo","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071410707","display_name":"Juan Li","orcid":"https://orcid.org/0000-0002-2037-4654","observed_orcids":["https://orcid.org/0000-0002-2037-4654"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Li","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069461912","display_name":"Ruixia Hou","orcid":"https://orcid.org/0000-0001-5976-3000","observed_orcids":["https://orcid.org/0000-0001-5976-3000"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruixia Hou","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089473461","display_name":"Yueai Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueai Cheng","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104268543","display_name":"Tong Qu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tong Qu","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100640705","display_name":"Xinhua Li","orcid":"https://orcid.org/0000-0002-8048-963X","observed_orcids":["https://orcid.org/0000-0002-8048-963X","https://orcid.org/0000-0003-3484-4511"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhua Li","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011029233","display_name":"Guohua Yin","orcid":"https://orcid.org/0000-0001-8327-061X","observed_orcids":["https://orcid.org/0000-0001-8327-061X"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guohua Yin","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100754886","display_name":"Kaiming Zhang","orcid":"https://orcid.org/0000-0001-9525-9944","observed_orcids":["https://orcid.org/0000-0001-9525-9944"]},"institutions":[{"id":"https://openalex.org/I4210134092","display_name":"Taiyuan Central Hospital","ror":"https://ror.org/040f10867","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134092"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kaiming Zhang","raw_affiliation_strings":["Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan ,","institution_ids":["https://openalex.org/I4210134092"]},{"raw_affiliation_string":"Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan City Central Hospital , Taiyuan 030009 , China","institution_ids":["https://openalex.org/I4210134092"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100754886"],"corresponding_institution_ids":["https://openalex.org/I4210134092"],"apc_list":{"value":3918,"currency":"GBP","value_usd":5008},"apc_paid":{"value":3918,"currency":"GBP","value_usd":5008},"fwci":1.081,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7359875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"192","issue":"1","first_page":"92","last_page":"103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lysine-2-hydroxyisobutyrylation","display_name":"lysine 2-hydroxyisobutyrylation","score":0.9570000171661377},{"id":"https://openalex.org/keywords/ebp1","display_name":"Ebp1","score":0.8560000061988831},{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/keratinocyte-proliferation","display_name":"keratinocyte proliferation","score":1.0},{"id":"https://openalex.org/keywords/rrna-synthesis","display_name":"ribosomal RNA synthesis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.7680000066757202},{"id":"https://openalex.org/keywords/hdac2","display_name":"HDAC2","score":0.9879999756813049},{"id":"https://openalex.org/keywords/post-translational-modification","display_name":"post-translational modification","score":0.8769999742507935},{"id":"https://openalex.org/keywords/imiquimod-induced-psoriasis","display_name":"imiquimod-induced psoriasis","score":0.8960000276565552}],"concepts":[{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.8513091802597046},{"id":"https://openalex.org/C2777074287","wikidata":"https://www.wikidata.org/wiki/Q1473931","display_name":"Keratinocyte","level":3,"score":0.6331909894943237},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.528144121170044},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4277230501174927},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.367395281791687},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34359097480773926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29346975684165955},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.18545672297477722},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13988643884658813},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11690852046012878},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0771891176700592}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008239","descriptor_name":"Lysine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035463","descriptor_name":"Pol1 Transcription Initiation Complex Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035463","descriptor_name":"Pol1 Transcription Initiation Complex Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bjd/ljae194","doi":"https://doi.org/10.1093/bjd/ljae194","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bjd/ljae194","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},{"id":"pmid:38752336","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38752336","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of dermatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/bjd/ljae194","doi":"https://doi.org/10.1093/bjd/ljae194","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bjd/ljae194","pdf_url":null,"source":{"id":"https://openalex.org/S45720283","display_name":"British Journal of Dermatology","issn_l":"0007-0963","issn":["0007-0963","1365-2133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5031070509","display_name":null,"funder_award_id":"82273539","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5396074223","display_name":null,"funder_award_id":"81773336","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6434352618","display_name":null,"funder_award_id":"81401360","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W2015384203","https://openalex.org/W2016369789","https://openalex.org/W2020474748","https://openalex.org/W2045566232","https://openalex.org/W2046301798","https://openalex.org/W2050216825","https://openalex.org/W2051503534","https://openalex.org/W2056325595","https://openalex.org/W2094512702","https://openalex.org/W2095413974","https://openalex.org/W2097933346","https://openalex.org/W2107432039","https://openalex.org/W2126556619","https://openalex.org/W2130623329","https://openalex.org/W2135821923","https://openalex.org/W2151234510","https://openalex.org/W2154249395","https://openalex.org/W2161298201","https://openalex.org/W2162002416","https://openalex.org/W2181797758","https://openalex.org/W2260855118","https://openalex.org/W2344542847","https://openalex.org/W2516289891","https://openalex.org/W2519830843","https://openalex.org/W2591965465","https://openalex.org/W2605312736","https://openalex.org/W2740419787","https://openalex.org/W2774396895","https://openalex.org/W2774906913","https://openalex.org/W2801986698","https://openalex.org/W2803068765","https://openalex.org/W2806138737","https://openalex.org/W2885738309","https://openalex.org/W2886655229","https://openalex.org/W2915758493","https://openalex.org/W2918780294","https://openalex.org/W2952973737","https://openalex.org/W3012736398","https://openalex.org/W3016817101","https://openalex.org/W4211077900","https://openalex.org/W4233561050","https://openalex.org/W4389021881","https://openalex.org/W6674183397"],"related_works":["https://openalex.org/W4400826386","https://openalex.org/W4400825685","https://openalex.org/W7160418722","https://openalex.org/W2952973737","https://openalex.org/W2752604522","https://openalex.org/W2801653477","https://openalex.org/W3089416385","https://openalex.org/W4231131756","https://openalex.org/W7212258178","https://openalex.org/W2807627990"],"abstract_inverted_index":{"BACKGROUND:":[0],"Psoriasis":[1],"is":[2,19],"a":[3,20,119],"prevalent":[4],"chronic":[5],"inflammatory":[6],"dermatosis":[7],"characterized":[8],"by":[9,239],"the":[10,37,45,68,100,183,187,256],"excessive":[11],"proliferation":[12,156,238],"of":[13,39,70,85,103,112,128,140,219,234,255,258],"keratinocytes":[14],"(KCs).":[15],"Lysine":[16],"2-hydroxyisobutyrylation":[17],"(Khib)":[18],"newly":[21],"identified":[22],"post-translational":[23],"modification":[24,32,48,84,114,251],"that":[25,182],"regulates":[26],"various":[27],"biological":[28],"processes.":[29],"Abnormal":[30],"Khib":[31,47,83,113,250],"has":[33],"been":[34],"associated":[35],"with":[36,81,123,135,146,167],"development":[38],"autoimmune":[40],"diseases.":[41],"OBJECTIVES:":[42],"To":[43],"investigate":[44,99],"abnormal":[46],"profile":[49,121],"and":[50,73,79,133,157,175,191,209,215,243,260],"its":[51],"pathogenic":[52],"role":[53],"in":[54,67,105,115,130,144,162,211,227],"psoriasis.":[55,106,137],"METHODS:":[56],"Liquid":[57],"chromatography-tandem":[58],"mass":[59],"spectrometry":[60],"was":[61,142,221],"used":[62],"to":[63,98,223],"analyse":[64],"Khib-modified":[65],"proteins":[66],"epidermis":[69],"psoriasis":[71,147,259],"lesions":[72,132,174],"healthy":[74],"control":[75],"skin.":[76],"Mutated":[77],"cells":[78],"mice":[80,134,166],"downregulated":[82,168],"ErbB3":[86],"binding":[87],"protein":[88,193],"1":[89],"(EBP1)":[90],"at":[91],"amino":[92],"acid":[93],"210":[94],"(EBP1Khib210)":[95],"were":[96],"generated,":[97],"functional":[101],"effects":[102],"EBP1Khib210":[104,129,141,152,220,235],"RESULTS:":[107],"Omics":[108],"analysis":[109],"revealed":[110],"dysregulation":[111],"psoriatic":[116,131,173],"lesions,":[117],"exhibiting":[118],"distinct":[120],"compared":[122],"controls.":[124],"We":[125],"found":[126,181],"downregulation":[127],"imiquimod-induced":[136],"Notably,":[138],"expression":[139],"upregulated":[143],"patients":[145],"following":[148],"effective":[149],"treatment.":[150],"Decreased":[151],"enhanced":[153,176],"KC":[154,177,216,237],"viability,":[155],"survival":[158],"but":[159],"inhibited":[160],"apoptosis":[161],"vitro.":[163],"Additionally,":[164],"Pa2g4K210A":[165],"Ebp1Khib210":[169],"exhibited":[170],"more":[171],"severe":[172],"proliferation.":[178,217],"Moreover,":[179],"we":[180],"EBP1K210A":[184],"mutation":[185],"increased":[186,212],"interaction":[188],"between":[189],"EBP1":[190],"nuclear":[192],"kinase":[194],"B":[195],"(Akt),":[196],"thereby":[197],"inhibiting":[198],"mouse":[199],"double":[200],"minute":[201],"2-mediated":[202],"transcription":[203],"initiation":[204],"factor":[205],"IA":[206],"(TIF-IA)":[207],"ubiquitination":[208],"resulting":[210],"rRNA":[213,245],"synthesis":[214],"Downregulation":[218,233],"attributed":[222],"an":[224],"inflammation-induced":[225],"increase":[226],"histone":[228],"deacetylase":[229],"2":[230],"expression.":[231],"CONCLUSIONS:":[232],"promoted":[236],"modulating":[240],"Akt":[241],"signalling":[242],"TIF-IA-mediated":[244],"synthesis.":[246],"These":[247],"insights":[248],"into":[249],"provide":[252],"better":[253],"understanding":[254],"pathogenesis":[257],"suggest":[261],"potential":[262],"therapeutic":[263],"targets.":[264]},"counts_by_year":[{"year":2026,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-05-17T00:00:00"}