{"id":"https://openalex.org/W4396924072","doi":"https://doi.org/10.3390/biologics4020011","title":"Cell-Based Therapies for the Treatment of Traumatic Brain Injury: Promises and Trajectories","display_name":"Cell-Based Therapies for the Treatment of Traumatic Brain Injury: Promises and Trajectories","publication_year":2024,"publication_date":"2024-05-11","ids":{"openalex":"https://openalex.org/W4396924072","doi":"https://doi.org/10.3390/biologics4020011"},"language":"en","primary_location":{"id":"doi:10.3390/biologics4020011","doi":"https://doi.org/10.3390/biologics4020011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biologics4020011","pdf_url":null,"source":{"id":"https://openalex.org/S4210200733","display_name":"Biologics","issn_l":"2673-8449","issn":["2673-8449"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/biologics4020011","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070717906","display_name":"Karl John Habashy","orcid":"https://orcid.org/0000-0003-1210-378X","observed_orcids":["https://orcid.org/0000-0003-1210-378X"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210147348","display_name":"Northwestern Medicine","ror":"https://ror.org/04fzwnh64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348"]},{"id":"https://openalex.org/I4390039227","display_name":"Robert H. Lurie Comprehensive Cancer Center of Northwestern University","ror":"https://ror.org/02p4far57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karl J. Habashy","raw_affiliation_strings":["Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA"],"raw_orcid":"https://orcid.org/0000-0003-1210-378X","affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077795589","display_name":"Saad Omais","orcid":"https://orcid.org/0000-0003-3660-2794","observed_orcids":["https://orcid.org/0000-0003-3660-2794"]},"institutions":[{"id":"https://openalex.org/I56306041","display_name":"Lebanese American University","ror":"https://ror.org/00hqkan37","country_code":"LB","type":"education","lineage":["https://openalex.org/I56306041"]}],"countries":["LB"],"is_corresponding":false,"raw_author_name":"Saad Omais","raw_affiliation_strings":["Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Beirut 1102 2801, Lebanon"],"raw_orcid":"https://orcid.org/0000-0003-3660-2794","affiliations":[{"raw_affiliation_string":"Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Beirut 1102 2801, Lebanon","institution_ids":["https://openalex.org/I56306041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102941927","display_name":"Benedikt E. Haupt","orcid":"https://orcid.org/0009-0003-1757-8423","observed_orcids":["https://orcid.org/0009-0003-1757-8423"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210147348","display_name":"Northwestern Medicine","ror":"https://ror.org/04fzwnh64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348"]},{"id":"https://openalex.org/I4390039227","display_name":"Robert H. Lurie Comprehensive Cancer Center of Northwestern University","ror":"https://ror.org/02p4far57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benedikt Haupt","raw_affiliation_strings":["Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA"],"raw_orcid":"https://orcid.org/0009-0003-1757-8423","affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060408739","display_name":"Adam M. Sonabend","orcid":"https://orcid.org/0000-0002-8347-1945","observed_orcids":["https://orcid.org/0000-0002-8347-1945"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210147348","display_name":"Northwestern Medicine","ror":"https://ror.org/04fzwnh64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348"]},{"id":"https://openalex.org/I4390039227","display_name":"Robert H. Lurie Comprehensive Cancer Center of Northwestern University","ror":"https://ror.org/02p4far57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Adam M. Sonabend","raw_affiliation_strings":["Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009978031","display_name":"Christopher S. Ahuja","orcid":"https://orcid.org/0000-0002-9910-148X","observed_orcids":["https://orcid.org/0000-0002-9910-148X"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I4210147348","display_name":"Northwestern Medicine","ror":"https://ror.org/04fzwnh64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348"]},{"id":"https://openalex.org/I4390039227","display_name":"Robert H. Lurie Comprehensive Cancer Center of Northwestern University","ror":"https://ror.org/02p4far57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christopher S. Ahuja","raw_affiliation_strings":["Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA"],"raw_orcid":"https://orcid.org/0000-0002-9910-148X","affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Northwestern Medicine Lou & Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210147348","https://openalex.org/I4390039227"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5009978031","https://openalex.org/A5060408739"],"corresponding_institution_ids":["https://openalex.org/I111979921","https://openalex.org/I4210147348","https://openalex.org/I4390039227"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1137},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1137},"fwci":1.0096,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.73797082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"4","issue":"2","first_page":"161","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9502000212669373,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.03530000150203705,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.996999979019165},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.9440000057220459},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.8939999938011169},{"id":"https://openalex.org/keywords/endogenous-stem-cells","display_name":"endogenous stem cells","score":0.7639999985694885},{"id":"https://openalex.org/keywords/nerve-regeneration","display_name":"nerve regeneration","score":0.7879999876022339},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.6959999799728394},{"id":"https://openalex.org/keywords/age-related-inflammation","display_name":"age-related inflammation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/tbi-epidemiology","display_name":"TBI epidemiology","score":0.8059999942779541},{"id":"https://openalex.org/keywords/falls-in-older-adults","display_name":"falls in older adults","score":0.8539999723434448},{"id":"https://openalex.org/keywords/good-manufacturing-practices","display_name":"good manufacturing practices","score":0.8180000185966492},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.7960000038146973},{"id":"https://openalex.org/keywords/patient-selection","display_name":"patient selection","score":0.5590000152587891},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.7009999752044678}],"concepts":[{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.838385820388794},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4537995755672455},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.42346084117889404},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3205317258834839},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2703680992126465},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1450079381465912}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3390/biologics4020011","doi":"https://doi.org/10.3390/biologics4020011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biologics4020011","pdf_url":null,"source":{"id":"https://openalex.org/S4210200733","display_name":"Biologics","issn_l":"2673-8449","issn":["2673-8449"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologics","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:75663a668b13416c91d41cc62d7e0ca4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/75663a668b13416c91d41cc62d7e0ca4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biologics, Vol 4, Iss 2, Pp 161-176 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/biologics4020011","doi":"https://doi.org/10.3390/biologics4020011","is_oa":true,"landing_page_url":"https://doi.org/10.3390/biologics4020011","pdf_url":null,"source":{"id":"https://openalex.org/S4210200733","display_name":"Biologics","issn_l":"2673-8449","issn":["2673-8449"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W1529097742","https://openalex.org/W1544045643","https://openalex.org/W1969905245","https://openalex.org/W1985530230","https://openalex.org/W2001068966","https://openalex.org/W2012253237","https://openalex.org/W2017830127","https://openalex.org/W2022668968","https://openalex.org/W2024361882","https://openalex.org/W2025935987","https://openalex.org/W2027251820","https://openalex.org/W2031057488","https://openalex.org/W2039000484","https://openalex.org/W2045023286","https://openalex.org/W2045314069","https://openalex.org/W2048699935","https://openalex.org/W2064933785","https://openalex.org/W2067448822","https://openalex.org/W2067856703","https://openalex.org/W2070439522","https://openalex.org/W2071425128","https://openalex.org/W2083994698","https://openalex.org/W2084217262","https://openalex.org/W2099299143","https://openalex.org/W2102560467","https://openalex.org/W2109518992","https://openalex.org/W2110282732","https://openalex.org/W2115188551","https://openalex.org/W2115533079","https://openalex.org/W2128332802","https://openalex.org/W2138977668","https://openalex.org/W2142046859","https://openalex.org/W2163135664","https://openalex.org/W2167705610","https://openalex.org/W2279054921","https://openalex.org/W2287467308","https://openalex.org/W2318512980","https://openalex.org/W2319937456","https://openalex.org/W2324995304","https://openalex.org/W2330447290","https://openalex.org/W2338578301","https://openalex.org/W2406652806","https://openalex.org/W2529762510","https://openalex.org/W2548344299","https://openalex.org/W2557223458","https://openalex.org/W2585733759","https://openalex.org/W2588683679","https://openalex.org/W2606329317","https://openalex.org/W2611289724","https://openalex.org/W2743814168","https://openalex.org/W2777050377","https://openalex.org/W2788489832","https://openalex.org/W2792385954","https://openalex.org/W2838836918","https://openalex.org/W2890140105","https://openalex.org/W2903325146","https://openalex.org/W2913684613","https://openalex.org/W2915296249","https://openalex.org/W2962677494","https://openalex.org/W2990737501","https://openalex.org/W3009157977","https://openalex.org/W3033500765","https://openalex.org/W3045013597","https://openalex.org/W3097485069","https://openalex.org/W3119011816","https://openalex.org/W3157365547","https://openalex.org/W3194859363","https://openalex.org/W4214734598","https://openalex.org/W4220803358","https://openalex.org/W4241343595","https://openalex.org/W4297983178","https://openalex.org/W4306179939","https://openalex.org/W4317214690","https://openalex.org/W4320923599","https://openalex.org/W4387773145","https://openalex.org/W4388202328","https://openalex.org/W4390645976","https://openalex.org/W4391750150"],"related_works":["https://openalex.org/W7116779645","https://openalex.org/W4285265701","https://openalex.org/W3166993375","https://openalex.org/W3008581903","https://openalex.org/W4410311253","https://openalex.org/W2128916981","https://openalex.org/W4200463443","https://openalex.org/W4307890197","https://openalex.org/W4407942477","https://openalex.org/W7203616365"],"abstract_inverted_index":{"Traumatic":[0],"Brain":[1],"Injury":[2],"(TBI)":[3],"is":[4,179],"a":[5,10,155,175],"debilitating":[6],"condition":[7],"that":[8,84],"poses":[9],"significant":[11,124],"public":[12],"health":[13],"concern.":[14],"Historically":[15],"linked":[16],"to":[17,46,61,126,136,142,181],"motor":[18],"vehicle":[19],"accidents,":[20],"the":[21,31,89,119,134,140,169,183,188],"epidemiology":[22],"of":[23,106,121,171,177,190],"TBI":[24,122,192],"has":[25],"evolved.":[26],"Falls":[27],"now":[28],"emerge":[29],"as":[30,111],"predominant":[32],"cause,":[33],"particularly":[34],"among":[35],"older":[36],"adults.":[37],"Sport-related":[38],"TBIs":[39],"have":[40,59],"also":[41],"garnered":[42],"increased":[43],"attention":[44],"due":[45],"concerns":[47],"regarding":[48],"long-term":[49],"neurological":[50],"sequelae.":[51],"To":[52],"date,":[53],"therapeutic":[54,95,172],"interventions":[55],"remain":[56],"limited":[57],"and":[58,74,91,118,168],"yet":[60],"yield":[62,182],"substantial":[63],"clinical":[64,137,163],"benefits.":[65],"Cell-based":[66],"therapies":[67,79,101],"offer":[68],"promising":[69,185],"avenues":[70],"for":[71],"neural":[72],"repair":[73],"regeneration:":[75],"endogenous":[76,82],"stem":[77,130],"cell":[78,100,131],"capitalize":[80],"on":[81],"pools":[83],"can":[85],"be":[86],"triggered":[87],"by":[88,94],"injury":[90],"further":[92],"enhanced":[93],"approaches.":[96],"In":[97],"contrast,":[98],"exogenous":[99,104],"provide":[102],"an":[103],"source":[105],"cells.":[107],"However,":[108],"challenges":[109,153],"such":[110],"age-related":[112,116],"decline":[113],"in":[114,162,187],"neurogenesis,":[115],"inflammation,":[117],"heterogeneity":[120],"present":[123],"hurdles":[125],"overcome.":[127],"Moreover,":[128],"translating":[129],"research":[132],"from":[133],"laboratory":[135],"applications":[138],"necessitates":[139],"adherence":[141],"good":[143],"manufacturing":[144],"practice":[145],"standards,":[146],"which":[147],"presents":[148],"distinct":[149],"obstacles.":[150],"Addressing":[151],"these":[152],"requires":[154],"multifaceted":[156],"approach,":[157],"including":[158],"careful":[159],"patient":[160],"selection":[161],"trials,":[164],"appropriate":[165],"experimental":[166],"models,":[167],"optimization":[170],"techniques.":[173],"Ultimately,":[174],"combination":[176],"strategies":[178],"likely":[180],"most":[184],"outcomes":[186],"pursuit":[189],"effective":[191],"therapies.":[193]},"counts_by_year":[{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-05-16T00:00:00"}